{"id":"https://openalex.org/W2099529971","doi":"https://doi.org/10.1111/j.1365-2958.2008.06477.x","title":"Sinorhizobium meliloti, a bacterium lacking the autoinducer\u20102 (AI\u20102) synthase, responds to AI\u20102 supplied by other bacteria","display_name":"Sinorhizobium meliloti, a bacterium lacking the autoinducer\u20102 (AI\u20102) synthase, responds to AI\u20102 supplied by other bacteria","publication_year":2008,"publication_date":"2008-10-13","ids":{"openalex":"https://openalex.org/W2099529971","doi":"https://doi.org/10.1111/j.1365-2958.2008.06477.x","mag":"2099529971","pmid":"https://pubmed.ncbi.nlm.nih.gov/18990189","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2759681"},"language":"en","primary_location":{"id":"doi:10.1111/j.1365-2958.2008.06477.x","doi":"https://doi.org/10.1111/j.1365-2958.2008.06477.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1365-2958.2008.06477.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-2958.2008.06477.x","source":{"id":"https://openalex.org/S102549058","display_name":"Molecular Microbiology","issn_l":"0950-382X","issn":["0950-382X","1365-2958"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Microbiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-2958.2008.06477.x","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091098373","display_name":"Catarina S. Pereira","orcid":"https://orcid.org/0000-0002-8437-7432","observed_orcids":["https://orcid.org/0000-0002-8437-7432"]},"institutions":[{"id":"https://openalex.org/I48057805","display_name":"Instituto Gulbenkian de Ci\u00eancia","ror":"https://ror.org/04b08hq31","country_code":"PT","type":"education","lineage":["https://openalex.org/I4405252639","https://openalex.org/I48057805"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Catarina S. Pereira","raw_affiliation_strings":["Bacterial Signaling Laboratory, Instituto Gulbenkian de Ci\u00eancia, Oeiras, Portugal","Bacterial Signaling Laboratory, Instituto de Tecnologia Qu\u00edmica e Biol\u00f3gica, Oeiras, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bacterial Signaling Laboratory, Instituto Gulbenkian de Ci\u00eancia, Oeiras, Portugal","institution_ids":["https://openalex.org/I48057805"]},{"raw_affiliation_string":"Bacterial Signaling Laboratory, Instituto de Tecnologia Qu\u00edmica e Biol\u00f3gica, Oeiras, Portugal","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049799621","display_name":"J. Randall McAuley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I118020396","display_name":"Swarthmore College","ror":"https://ror.org/012dg8a96","country_code":"US","type":"education","lineage":["https://openalex.org/I118020396"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Randall McAuley","raw_affiliation_strings":["Department of Chemistry and Biochemistry, Swarthmore College, Swarthmore, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, Swarthmore College, Swarthmore, PA, USA","institution_ids":["https://openalex.org/I118020396"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031848177","display_name":"Michiko E. Taga","orcid":"https://orcid.org/0000-0002-9148-5925","observed_orcids":["https://orcid.org/0000-0002-9148-5925"]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michiko E. Taga","raw_affiliation_strings":["Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001177688","display_name":"Karina B. Xavier","orcid":"https://orcid.org/0000-0001-5210-1434","observed_orcids":["https://orcid.org/0000-0001-5210-1434"]},"institutions":[{"id":"https://openalex.org/I48057805","display_name":"Instituto Gulbenkian de Ci\u00eancia","ror":"https://ror.org/04b08hq31","country_code":"PT","type":"education","lineage":["https://openalex.org/I4405252639","https://openalex.org/I48057805"]}],"countries":["PT"],"is_corresponding":true,"raw_author_name":"Karina B. Xavier","raw_affiliation_strings":["**E-mail [email protected] ; Tel. (+1) 610 957 6063;","*E-mail [email protected] ; Tel. +351 21 4464655;","Bacterial Signaling Laboratory, Instituto Gulbenkian de Cie\u0302ncia, Oeiras, Portugal","Bacterial Signaling Laboratory, Instituto de Tecnologia Qui\u0301mica e Biolo\u0301gica, Oeiras, Portugal","**E-mail [email protected]","Bacterial Signaling Laboratory, Instituto Gulbenkian de Ci\u00eancia, Oeiras, Portugal","Bacterial Signaling Laboratory, Instituto de Tecnologia Qu\u00edmica e Biol\u00f3gica, Oeiras, Portugal","Tel. (+1) 610 957 6063","Tel. +351 21 4464655"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"**E-mail [email protected] ; Tel. (+1) 610 957 6063;","institution_ids":[]},{"raw_affiliation_string":"*E-mail [email protected] ; Tel. +351 21 4464655;","institution_ids":[]},{"raw_affiliation_string":"Bacterial Signaling Laboratory, Instituto Gulbenkian de Cie\u0302ncia, Oeiras, Portugal","institution_ids":["https://openalex.org/I48057805"]},{"raw_affiliation_string":"Bacterial Signaling Laboratory, Instituto de Tecnologia Qui\u0301mica e Biolo\u0301gica, Oeiras, Portugal","institution_ids":[]},{"raw_affiliation_string":"**E-mail [email protected]","institution_ids":[]},{"raw_affiliation_string":"Bacterial Signaling Laboratory, Instituto Gulbenkian de Ci\u00eancia, Oeiras, Portugal","institution_ids":["https://openalex.org/I48057805"]},{"raw_affiliation_string":"Bacterial Signaling Laboratory, Instituto de Tecnologia Qu\u00edmica e Biol\u00f3gica, Oeiras, Portugal","institution_ids":[]},{"raw_affiliation_string":"Tel. (+1) 610 957 6063","institution_ids":[]},{"raw_affiliation_string":"Tel. +351 21 4464655","institution_ids":[]}]},{"author_position":"last","author":{"id":null,"display_name":"Stephen T. Miller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I118020396","display_name":"Swarthmore College","ror":"https://ror.org/012dg8a96","country_code":"US","type":"education","lineage":["https://openalex.org/I118020396"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Stephen T. Miller","raw_affiliation_strings":["**E-mail [email protected] ; Tel. (+1) 610 957 6063;","*E-mail [email protected] ; Tel. +351 21 4464655;","Department of Chemistry and Biochemistry, Swarthmore College, Swarthmore, PA, USA","**E-mail [email protected]","Tel. (+1) 610 957 6063","Tel. +351 21 4464655"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"**E-mail [email protected] ; Tel. (+1) 610 957 6063;","institution_ids":[]},{"raw_affiliation_string":"*E-mail [email protected] ; Tel. +351 21 4464655;","institution_ids":[]},{"raw_affiliation_string":"Department of Chemistry and Biochemistry, Swarthmore College, Swarthmore, PA, USA","institution_ids":["https://openalex.org/I118020396"]},{"raw_affiliation_string":"**E-mail [email protected]","institution_ids":[]},{"raw_affiliation_string":"Tel. (+1) 610 957 6063","institution_ids":[]},{"raw_affiliation_string":"Tel. +351 21 4464655","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5001177688"],"corresponding_institution_ids":["https://openalex.org/I118020396","https://openalex.org/I48057805"],"apc_list":{"value":4430,"currency":"USD","value_usd":4430},"apc_paid":null,"fwci":3.0135,"has_fulltext":true,"cited_by_count":79,"citation_normalized_percentile":{"value":0.91833989,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"70","issue":"5","first_page":"1223","last_page":"1235"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10593","display_name":"Bacterial biofilms and quorum sensing","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10593","display_name":"Bacterial biofilms and quorum sensing","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10076","display_name":"Plant-Microbe Interactions and Immunity","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sinorhizobium-meliloti","display_name":"Sinorhizobium meliloti","score":0.9929999709129333},{"id":"https://openalex.org/keywords/autoinducer-2","display_name":"autoinducer-2","score":0.996999979019165},{"id":"https://openalex.org/keywords/quorum-sensing","display_name":"quorum sensing","score":0.9599999785423279},{"id":"https://openalex.org/keywords/periplasmic-binding-protein","display_name":"periplasmic binding protein","score":0.8560000061988831},{"id":"https://openalex.org/keywords/pectobacterium-carotovorum","display_name":"Erwinia carotovora","score":0.9139999747276306},{"id":"https://openalex.org/keywords/virulence-regulation","display_name":"virulence regulation","score":0.8460000157356262},{"id":"https://openalex.org/keywords/plant-symbionts","display_name":"plant symbionts","score":0.8130000233650208}],"concepts":[{"id":"https://openalex.org/C2777304268","wikidata":"https://www.wikidata.org/wiki/Q2696072","display_name":"Sinorhizobium meliloti","level":4,"score":0.9612343311309814},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8832212686538696},{"id":"https://openalex.org/C203075996","wikidata":"https://www.wikidata.org/wiki/Q139677","display_name":"Operon","level":4,"score":0.7271321415901184},{"id":"https://openalex.org/C95282255","wikidata":"https://www.wikidata.org/wiki/Q4826353","display_name":"Autoinducer","level":5,"score":0.5699533820152283},{"id":"https://openalex.org/C60987743","wikidata":"https://www.wikidata.org/wiki/Q1460232","display_name":"Virulence","level":3,"score":0.5084013342857361},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.46175527572631836},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.42895883321762085},{"id":"https://openalex.org/C2778495000","wikidata":"https://www.wikidata.org/wiki/Q134827","display_name":"Erwinia","level":3,"score":0.4276081919670105},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4257311224937439},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.416675865650177},{"id":"https://openalex.org/C118687296","wikidata":"https://www.wikidata.org/wiki/Q905754","display_name":"Quorum sensing","level":4,"score":0.3886658549308777},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3702741265296936},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.36880457401275635}],"mesh":[{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005798","descriptor_name":"Genes, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006714","descriptor_name":"Homoserine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D006714","descriptor_name":"Homoserine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007783","descriptor_name":"Lactones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009876","descriptor_name":"Operon","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010429","descriptor_name":"Pentoses","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011956","descriptor_name":"Receptors, Cell Surface","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011956","descriptor_name":"Receptors, Cell Surface","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012329","descriptor_name":"RNA, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012486","descriptor_name":"Salmonella typhimurium","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012486","descriptor_name":"Salmonella typhimurium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015964","descriptor_name":"Gene Expression Regulation, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016962","descriptor_name":"Sinorhizobium meliloti","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016962","descriptor_name":"Sinorhizobium meliloti","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020133","descriptor_name":"Reverse Transcriptase Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053038","descriptor_name":"Quorum Sensing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1111/j.1365-2958.2008.06477.x","doi":"https://doi.org/10.1111/j.1365-2958.2008.06477.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1365-2958.2008.06477.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-2958.2008.06477.x","source":{"id":"https://openalex.org/S102549058","display_name":"Molecular Microbiology","issn_l":"0950-382X","issn":["0950-382X","1365-2958"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Microbiology","raw_type":"journal-article"},{"id":"pmid:18990189","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18990189","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular microbiology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2759681","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2759681","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Mol Microbiol","raw_type":"Text"},{"id":"pmh:oai:works.swarthmore.edu:fac-chemistry-1054","doi":null,"is_oa":false,"landing_page_url":"https://works.swarthmore.edu/fac-chemistry/55","pdf_url":null,"source":{"id":"https://openalex.org/S4377196506","display_name":"Works - Scholarship, Research, & Creative Expression (Swarthmore College)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I118020396","host_organization_name":"Swarthmore College","host_organization_lineage":["https://openalex.org/I118020396"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Chemistry & Biochemistry Faculty Works","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1111/j.1365-2958.2008.06477.x","doi":"https://doi.org/10.1111/j.1365-2958.2008.06477.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1365-2958.2008.06477.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-2958.2008.06477.x","source":{"id":"https://openalex.org/S102549058","display_name":"Molecular Microbiology","issn_l":"0950-382X","issn":["0950-382X","1365-2958"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Microbiology","raw_type":"journal-article"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/15","display_name":"Life on land","score":0.4699999988079071}],"study_designs":[],"awards":[{"id":"https://openalex.org/G44154009","display_name":"Characterization of receptors of the bacterial signaling molecule autoinducer-2","funder_award_id":"R15AI074041","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G5469844544","display_name":"Identifica\u00e7\u00e3o e caracteriza\u00e7\u00e3o de sistemas de detec\u00e7\u00e3o de qu\u00f3rum envolvidos na comunica\u00e7\u00e3o entre diferentes esp\u00e9cies de bact\u00e9rias","funder_award_id":"PTDC/BIA-BCM/73676/2006","funder_id":"https://openalex.org/F4320334779","funder_display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia"},{"id":"https://openalex.org/G59962948","display_name":"AI-2 QUORUM SENSING: ITS FUNCTION IN BACTERIAL INTER-SPECIES COMMUNICATION","funder_award_id":"SFRH/BD/28543/2006","funder_id":"https://openalex.org/F4320334779","funder_display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia"},{"id":"https://openalex.org/G7561149228","display_name":null,"funder_award_id":"AI074041","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320306279","display_name":"Jane Coffin Childs Memorial Fund for Medical Research","ror":"https://ror.org/04yhme281"},{"id":"https://openalex.org/F4320306315","display_name":"Camille and Henry Dreyfus Foundation","ror":"https://ror.org/019p8h045"},{"id":"https://openalex.org/F4320309292","display_name":"Princeton University","ror":"https://ror.org/00hx57361"},{"id":"https://openalex.org/F4320324459","display_name":"Funda\u00e7\u00e3o Luso-Americana para o Desenvolvimento","ror":"https://ror.org/03jgmp057"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320334779","display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","ror":"https://ror.org/00snfqn58"},{"id":"https://openalex.org/F4320335265","display_name":"Institute of Molecular and Cell Biology","ror":"https://ror.org/04xpsrn94"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2099529971.pdf","grobid_xml":"https://content.openalex.org/works/W2099529971.grobid-xml"},"referenced_works_count":48,"referenced_works":["https://openalex.org/W255996521","https://openalex.org/W1530687839","https://openalex.org/W1561454240","https://openalex.org/W1851276803","https://openalex.org/W1927570869","https://openalex.org/W1946514467","https://openalex.org/W1959548112","https://openalex.org/W1972435034","https://openalex.org/W1991095439","https://openalex.org/W1992058164","https://openalex.org/W1993616876","https://openalex.org/W1994462493","https://openalex.org/W1996872292","https://openalex.org/W2001641653","https://openalex.org/W2002276562","https://openalex.org/W2008119892","https://openalex.org/W2016402044","https://openalex.org/W2018093936","https://openalex.org/W2022959719","https://openalex.org/W2025248886","https://openalex.org/W2026819839","https://openalex.org/W2043213635","https://openalex.org/W2050833028","https://openalex.org/W2052255348","https://openalex.org/W2057802070","https://openalex.org/W2069228394","https://openalex.org/W2080655266","https://openalex.org/W2100460169","https://openalex.org/W2102635879","https://openalex.org/W2103359264","https://openalex.org/W2108808336","https://openalex.org/W2109184569","https://openalex.org/W2113490404","https://openalex.org/W2115335630","https://openalex.org/W2115682970","https://openalex.org/W2126055663","https://openalex.org/W2137887161","https://openalex.org/W2138307476","https://openalex.org/W2144081223","https://openalex.org/W2144640625","https://openalex.org/W2146537129","https://openalex.org/W2153076508","https://openalex.org/W2161746138","https://openalex.org/W2166345625","https://openalex.org/W2167637231","https://openalex.org/W2168557435","https://openalex.org/W2320616319","https://openalex.org/W4229932570"],"related_works":["https://openalex.org/W2380960518","https://openalex.org/W2011102133","https://openalex.org/W2168940509","https://openalex.org/W2052255348","https://openalex.org/W2411014110","https://openalex.org/W2527496728","https://openalex.org/W2112476086","https://openalex.org/W4408956674","https://openalex.org/W2914292693","https://openalex.org/W2127347791"],"abstract_inverted_index":{"Many":[0],"bacterial":[1],"species":[2,183],"respond":[3,39],"to":[4,40,161,164],"the":[5,25,28,77,98,151,178],"quorum-sensing":[6],"signal":[7,141],"autoinducer-2":[8],"(AI-2)":[9],"by":[10,43,82,154],"regulating":[11],"different":[12],"niche-specific":[13],"genes.":[14],"Here,":[15],"we":[16],"show":[17],"that":[18,48,56,72,136,170],"Sinorhizobium":[19],"meliloti,":[20],"a":[21,52,129,140,157],"plant":[22,158],"symbiont":[23],"lacking":[24],"gene":[26,88],"for":[27,102],"AI-2":[29,36,41,79,103,122,137,152,163,179],"synthase,":[30],"while":[31],"not":[32,127],"capable":[33,174],"of":[34,62,84,97,175,181],"producing":[35],"can":[37,148],"nonetheless":[38],"produced":[42],"other":[44,182],"species.":[45],"We":[46],"demonstrate":[47],"S.":[49,109,124,143,146,171],"meliloti":[50,110,125,147,172],"has":[51],"periplasmic":[53],"binding":[54],"protein":[55,64],"binds":[57,74],"AI-2.":[58],"The":[59,87],"crystal":[60],"structure":[61],"this":[63,117],"(here":[65],"named":[66],"SmlsrB)":[67],"with":[68,95,186],"its":[69],"ligand":[70],"reveals":[71],"it":[73],"(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran":[75],"(R-THMF),":[76],"identical":[78],"isomer":[80],"recognized":[81],"LsrB":[83],"Salmonella":[85],"typhimurium.":[86],"encoding":[89],"SmlsrB":[90],"is":[91,173],"in":[92,105,116,121,142],"an":[93],"operon":[94,118],"orthologues":[96],"lsr":[99],"genes":[100],"required":[101],"internalization":[104],"enteric":[106],"bacteria.":[107],"Accordingly,":[108],"internalizes":[111],"exogenous":[112],"AI-2,":[113,134],"and":[114,184],"mutants":[115],"are":[119],"defective":[120],"internalization.":[123],"does":[126],"gain":[128],"metabolic":[130],"benefit":[131],"from":[132],"internalizing":[133],"suggesting":[135],"functions":[138],"as":[139,190],"meliloti.":[144],"Furthermore,":[145],"completely":[149],"eliminate":[150],"secreted":[153],"Erwinia":[155],"carotovora,":[156],"pathogen":[159],"shown":[160],"use":[162],"regulate":[165],"virulence.":[166,191],"Our":[167],"findings":[168],"suggest":[169],"'eavesdropping'":[176],"on":[177],"signalling":[180],"interfering":[185],"AI-2-regulated":[187],"behaviours":[188],"such":[189]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":9}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}