{"id":"https://openalex.org/W2099485242","doi":"https://doi.org/10.1006/jmcc.1996.0300","title":"Altered Expression of Atrial Natriuretic Peptide and Contractile Protein Genes in Hypertrophied Ventricle of JVS Mice with Systemic Carnitine Deficiency","display_name":"Altered Expression of Atrial Natriuretic Peptide and Contractile Protein Genes in Hypertrophied Ventricle of JVS Mice with Systemic Carnitine Deficiency","publication_year":1997,"publication_date":"1997-02-01","ids":{"openalex":"https://openalex.org/W2099485242","doi":"https://doi.org/10.1006/jmcc.1996.0300","mag":"2099485242","pmid":"https://pubmed.ncbi.nlm.nih.gov/9140816"},"language":"en","primary_location":{"id":"doi:10.1006/jmcc.1996.0300","doi":"https://doi.org/10.1006/jmcc.1996.0300","is_oa":false,"landing_page_url":"https://doi.org/10.1006/jmcc.1996.0300","pdf_url":null,"source":{"id":"https://openalex.org/S111163638","display_name":"Journal of Molecular and Cellular Cardiology","issn_l":"0022-2828","issn":["0022-2828","1095-8584"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular and Cellular Cardiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005203226","display_name":"Kosei Yoshimine","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107139324","display_name":"Kagoshima University","ror":"https://ror.org/03ss88z23","country_code":"JP","type":"education","lineage":["https://openalex.org/I107139324"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kosei Yoshimine","raw_affiliation_strings":["Department of Biochemistry, Faculty of Medicine, Kagoshima University, Japan","Department of Biochemistry, Kagoshima University, Kagoshima, 890","Department of Internal Medicine, Kagoshima University, Kagoshima, 890"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Faculty of Medicine, Kagoshima University, Japan","institution_ids":["https://openalex.org/I107139324"]},{"raw_affiliation_string":"Department of Biochemistry, Kagoshima University, Kagoshima, 890","institution_ids":["https://openalex.org/I107139324"]},{"raw_affiliation_string":"Department of Internal Medicine, Kagoshima University, Kagoshima, 890","institution_ids":["https://openalex.org/I107139324"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046666678","display_name":"Masahisa Horiuchi","orcid":"https://orcid.org/0000-0003-1852-7495","observed_orcids":["https://orcid.org/0000-0003-1852-7495"]},"institutions":[{"id":"https://openalex.org/I107139324","display_name":"Kagoshima University","ror":"https://ror.org/03ss88z23","country_code":"JP","type":"education","lineage":["https://openalex.org/I107139324"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Masahisa Horiuchi","raw_affiliation_strings":["Department of Biochemistry, Kagoshima University, Kagoshima, 890"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Kagoshima University, Kagoshima, 890","institution_ids":["https://openalex.org/I107139324"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111752387","display_name":"Syusaku SUZUKI","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107139324","display_name":"Kagoshima University","ror":"https://ror.org/03ss88z23","country_code":"JP","type":"education","lineage":["https://openalex.org/I107139324"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Syusaku Suzuki","raw_affiliation_strings":["Institute of Laboratory Animal Sciences, Kagoshima University, Kagoshima, 890"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Laboratory Animal Sciences, Kagoshima University, Kagoshima, 890","institution_ids":["https://openalex.org/I107139324"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101914434","display_name":"Keiko Kobayashi","orcid":"https://orcid.org/0000-0002-2975-5082","observed_orcids":["https://orcid.org/0000-0002-2975-5082"]},"institutions":[{"id":"https://openalex.org/I107139324","display_name":"Kagoshima University","ror":"https://ror.org/03ss88z23","country_code":"JP","type":"education","lineage":["https://openalex.org/I107139324"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Keiko Kobayashi","raw_affiliation_strings":["Department of Biochemistry, Kagoshima University, Kagoshima, 890"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Kagoshima University, Kagoshima, 890","institution_ids":["https://openalex.org/I107139324"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111977863","display_name":"Jalil Md. Abdul","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107139324","display_name":"Kagoshima University","ror":"https://ror.org/03ss88z23","country_code":"JP","type":"education","lineage":["https://openalex.org/I107139324"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Jalil Md. Abdul","raw_affiliation_strings":["Department of Biochemistry, Kagoshima University, Kagoshima, 890"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Kagoshima University, Kagoshima, 890","institution_ids":["https://openalex.org/I107139324"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014980661","display_name":"Mina Masuda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107139324","display_name":"Kagoshima University","ror":"https://ror.org/03ss88z23","country_code":"JP","type":"education","lineage":["https://openalex.org/I107139324"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mina Masuda","raw_affiliation_strings":["Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Kagoshima University, Kagoshima, 890","Department of Biochemistry, Kagoshima University, Kagoshima, 890"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Kagoshima University, Kagoshima, 890","institution_ids":["https://openalex.org/I107139324"]},{"raw_affiliation_string":"Department of Biochemistry, Kagoshima University, Kagoshima, 890","institution_ids":["https://openalex.org/I107139324"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047574380","display_name":"Mineko Tomomura","orcid":"https://orcid.org/0000-0002-4960-4679","observed_orcids":["https://orcid.org/0000-0002-4960-4679"]},"institutions":[{"id":"https://openalex.org/I107139324","display_name":"Kagoshima University","ror":"https://ror.org/03ss88z23","country_code":"JP","type":"education","lineage":["https://openalex.org/I107139324"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mineko Tomomura","raw_affiliation_strings":["Department of Biochemistry, Kagoshima University, Kagoshima, 890"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Kagoshima University, Kagoshima, 890","institution_ids":["https://openalex.org/I107139324"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074060371","display_name":"Yoshihiro Ogawa","orcid":"https://orcid.org/0000-0002-0834-2836","observed_orcids":["https://orcid.org/0000-0002-0834-2836"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshihiro Ogawa","raw_affiliation_strings":["Second Division, Department of Medicine, Kyoto University School of Medicine, Kyoto, 606, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Second Division, Department of Medicine, Kyoto University School of Medicine, Kyoto, 606, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109981066","display_name":"Hiroshi Itoh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroshi Itoh","raw_affiliation_strings":["Second Division, Department of Medicine, Kyoto University School of Medicine, Kyoto, 606, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Second Division, Department of Medicine, Kyoto University School of Medicine, Kyoto, 606, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105832217","display_name":"Kazuwa Nakao","orcid":"https://orcid.org/0000-0003-3483-4196","observed_orcids":["https://orcid.org/0000-0003-3483-4196"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuwa Nakao","raw_affiliation_strings":["Second Division, Department of Medicine, Kyoto University School of Medicine, Kyoto, 606, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Second Division, Department of Medicine, Kyoto University School of Medicine, Kyoto, 606, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110191950","display_name":"Mituhiro Osame","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107139324","display_name":"Kagoshima University","ror":"https://ror.org/03ss88z23","country_code":"JP","type":"education","lineage":["https://openalex.org/I107139324"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mituhiro Osame","raw_affiliation_strings":["Department of Internal Medicine, Kagoshima University, Kagoshima, 890"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Kagoshima University, Kagoshima, 890","institution_ids":["https://openalex.org/I107139324"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006070257","display_name":"Takeyori Saheki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107139324","display_name":"Kagoshima University","ror":"https://ror.org/03ss88z23","country_code":"JP","type":"education","lineage":["https://openalex.org/I107139324"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takeyori Saheki","raw_affiliation_strings":["Department of Biochemistry, Kagoshima University, Kagoshima, 890"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Kagoshima University, Kagoshima, 890","institution_ids":["https://openalex.org/I107139324"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5046666678"],"corresponding_institution_ids":["https://openalex.org/I107139324"],"apc_list":{"value":4120,"currency":"USD","value_usd":4120},"apc_paid":null,"fwci":1.7863,"has_fulltext":false,"cited_by_count":21,"citation_normalized_percentile":{"value":0.86513986,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"29","issue":"2","first_page":"571","last_page":"578"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.6083999872207642,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.6083999872207642,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.24040000140666962,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.04500000178813934,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/carnitine-deficiency","display_name":"carnitine deficiency","score":0.9210000038146973},{"id":"https://openalex.org/keywords/cardiac-hypertrophy","display_name":"cardiac hypertrophy","score":0.9549999833106995},{"id":"https://openalex.org/keywords/atrial-natriuretic-peptide","display_name":"atrial natriuretic peptide","score":0.9940000176429749},{"id":"https://openalex.org/keywords/beta-myosin-heavy-chain","display_name":"beta-myosin heavy chain","score":0.9589999914169312},{"id":"https://openalex.org/keywords/alpha-myosin-heavy-chain","display_name":"alpha-myosin heavy chain","score":0.9259999990463257},{"id":"https://openalex.org/keywords/l-carnitine-supplementation","display_name":"carnitine supplementation","score":0.8330000042915344},{"id":"https://openalex.org/keywords/aortic-constriction","display_name":"aortic constriction","score":0.6890000104904175}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.847747802734375},{"id":"https://openalex.org/C2778921608","wikidata":"https://www.wikidata.org/wiki/Q2002035","display_name":"Ventricle","level":2,"score":0.7180795669555664},{"id":"https://openalex.org/C2778069365","wikidata":"https://www.wikidata.org/wiki/Q78185357","display_name":"Atrial natriuretic peptide","level":2,"score":0.6596644520759583},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.636400580406189},{"id":"https://openalex.org/C8741621","wikidata":"https://www.wikidata.org/wiki/Q18030203","display_name":"NPR1","level":4,"score":0.6109137535095215},{"id":"https://openalex.org/C3156946","wikidata":"https://www.wikidata.org/wiki/Q18030205","display_name":"NPR2","level":4,"score":0.604952871799469},{"id":"https://openalex.org/C2778435403","wikidata":"https://www.wikidata.org/wiki/Q243309","display_name":"Carnitine","level":2,"score":0.5870919227600098},{"id":"https://openalex.org/C2775915353","wikidata":"https://www.wikidata.org/wiki/Q1571529","display_name":"Natriuretic peptide","level":3,"score":0.4679478704929352},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.37121567130088806},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3290095031261444},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.18906477093696594}],"mesh":[{"descriptor_ui":"D000199","descriptor_name":"Actins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000199","descriptor_name":"Actins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001835","descriptor_name":"Body Weight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002331","descriptor_name":"Carnitine","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":true},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006332","descriptor_name":"Cardiomegaly","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008809","descriptor_name":"Mice, Inbred C3H","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008817","descriptor_name":"Mice, Mutant Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009200","descriptor_name":"Myocardial Contraction","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009320","descriptor_name":"Atrial Natriuretic Factor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009320","descriptor_name":"Atrial Natriuretic Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009929","descriptor_name":"Organ Size","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018507","descriptor_name":"Gene Expression Regulation, Developmental","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018995","descriptor_name":"Myosin Heavy Chains","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018995","descriptor_name":"Myosin Heavy Chains","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1006/jmcc.1996.0300","doi":"https://doi.org/10.1006/jmcc.1996.0300","is_oa":false,"landing_page_url":"https://doi.org/10.1006/jmcc.1996.0300","pdf_url":null,"source":{"id":"https://openalex.org/S111163638","display_name":"Journal of Molecular and Cellular Cardiology","issn_l":"0022-2828","issn":["0022-2828","1095-8584"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular and Cellular Cardiology","raw_type":"journal-article"},{"id":"pmid:9140816","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9140816","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of molecular and cellular cardiology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9476000070571899,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320912","display_name":"Ministry of Education, Culture, Sports, Science and Technology","ror":"https://ror.org/048rj2z13"},{"id":"https://openalex.org/F4320325284","display_name":"Ono Medical Research Foundation","ror":"https://ror.org/00krdxg91"},{"id":"https://openalex.org/F4320328055","display_name":"Kimura Memorial Heart Foundation","ror":"https://ror.org/04rafes67"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":3,"referenced_works":["https://openalex.org/W1581398592","https://openalex.org/W1971437635","https://openalex.org/W2289140497"],"related_works":["https://openalex.org/W2290676543","https://openalex.org/W2019366767","https://openalex.org/W1592812956","https://openalex.org/W2111099596","https://openalex.org/W1992832034","https://openalex.org/W2078221029","https://openalex.org/W2433812919","https://openalex.org/W1977160397","https://openalex.org/W7095680767","https://openalex.org/W1985633127"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}