{"id":"https://openalex.org/W2099190822","doi":"https://doi.org/10.1136/bcr.05.2011.4243","title":"Severe consequences of carbamazepine exposure in utero: Figure 1","display_name":"Severe consequences of carbamazepine exposure in utero: Figure 1","publication_year":2011,"publication_date":"2011-08-05","ids":{"openalex":"https://openalex.org/W2099190822","doi":"https://doi.org/10.1136/bcr.05.2011.4243","mag":"2099190822","pmid":"https://pubmed.ncbi.nlm.nih.gov/22687674","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4545117"},"language":"en","primary_location":{"id":"doi:10.1136/bcr.05.2011.4243","doi":"https://doi.org/10.1136/bcr.05.2011.4243","is_oa":true,"landing_page_url":"https://doi.org/10.1136/bcr.05.2011.4243","pdf_url":"https://casereports.bmj.com/content/casereports/2011/bcr.05.2011.4243.full.pdf","source":{"id":"https://openalex.org/S141953298","display_name":"BMJ Case Reports","issn_l":"1757-790X","issn":["1757-790X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ Case Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://casereports.bmj.com/content/casereports/2011/bcr.05.2011.4243.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Antonio Bravo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210110176","display_name":"Hospital Central Dr. Ignacio Morones Prieto","ror":"https://ror.org/01m7mrx20","country_code":"MX","type":"healthcare","lineage":["https://openalex.org/I4210110176"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Antonio Bravo","raw_affiliation_strings":["Department of Child Neurology, Hospital Central Dr Ignacio Morones Prieto, San Luis Potos\u00ed, M\u00e9xico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Child Neurology, Hospital Central Dr Ignacio Morones Prieto, San Luis Potos\u00ed, M\u00e9xico","institution_ids":["https://openalex.org/I4210110176"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Dolores Hernandez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I169046204","display_name":"Universidad Aut\u00f3noma de Nuevo Le\u00f3n","ror":"https://ror.org/01fh86n78","country_code":"MX","type":"education","lineage":["https://openalex.org/I169046204"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Dolores Hernandez","raw_affiliation_strings":["Department of Genetics, School of Medicine, UANL, Nuevo Le\u00f3n, M\u00e9xico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, School of Medicine, UANL, Nuevo Le\u00f3n, M\u00e9xico","institution_ids":["https://openalex.org/I169046204"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059113261","display_name":"Laura Mart\u00ednez-Villarreal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I169046204","display_name":"Universidad Aut\u00f3noma de Nuevo Le\u00f3n","ror":"https://ror.org/01fh86n78","country_code":"MX","type":"education","lineage":["https://openalex.org/I169046204"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Laura Martinez-Villarreal","raw_affiliation_strings":["Department of Genetics, School of Medicine, UANL, Nuevo Le\u00f3n, M\u00e9xico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, School of Medicine, UANL, Nuevo Le\u00f3n, M\u00e9xico","institution_ids":["https://openalex.org/I169046204"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Gabriela Elizondo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I169046204","display_name":"Universidad Aut\u00f3noma de Nuevo Le\u00f3n","ror":"https://ror.org/01fh86n78","country_code":"MX","type":"education","lineage":["https://openalex.org/I169046204"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Gabriela Elizondo","raw_affiliation_strings":["Department of Genetics, School of Medicine, UANL, Nuevo Le\u00f3n, M\u00e9xico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, School of Medicine, UANL, Nuevo Le\u00f3n, M\u00e9xico","institution_ids":["https://openalex.org/I169046204"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090984896","display_name":"Carmen Esmer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210110176","display_name":"Hospital Central Dr. Ignacio Morones Prieto","ror":"https://ror.org/01m7mrx20","country_code":"MX","type":"healthcare","lineage":["https://openalex.org/I4210110176"]}],"countries":["MX"],"is_corresponding":true,"raw_author_name":"Carmen Esmer","raw_affiliation_strings":["Department of Genetics, Hospital Central \u2018Dr Ignacio Morones Prieto\u2019, San Luis Potos\u00ed, M\u00e9xico","carmenesmer{at}hotmail.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Hospital Central \u2018Dr Ignacio Morones Prieto\u2019, San Luis Potos\u00ed, M\u00e9xico","institution_ids":["https://openalex.org/I4210110176"]},{"raw_affiliation_string":"carmenesmer{at}hotmail.com","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5090984896"],"corresponding_institution_ids":["https://openalex.org/I4210110176"],"apc_list":null,"apc_paid":null,"fwci":0.6081,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.74031008,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"2011","issue":null,"first_page":"bcr0520114243","last_page":"bcr0520114243"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12229","display_name":"Pharmacological Effects and Toxicity Studies","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12229","display_name":"Pharmacological Effects and Toxicity Studies","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11633","display_name":"Prenatal Substance Exposure Effects","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11964","display_name":"Pregnancy and Medication Impact","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/carbamazepine","display_name":"carbamazepine","score":0.9629999995231628},{"id":"https://openalex.org/keywords/anticonvulsant-teratogenicity","display_name":"anticonvulsant teratogenicity","score":0.8339999914169312},{"id":"https://openalex.org/keywords/facial-dysmorphism","display_name":"facial dysmorphism","score":0.7649999856948853},{"id":"https://openalex.org/keywords/myelomeningocele","display_name":"myelomeningocele","score":0.9509999752044678},{"id":"https://openalex.org/keywords/hypoplastic-nails","display_name":"hypoplastic nails","score":0.7409999966621399},{"id":"https://openalex.org/keywords/neonatal-neutropenia","display_name":"neonatal neutropenia","score":0.8450000286102295},{"id":"https://openalex.org/keywords/pulmonary-hypertension","display_name":"pulmonary hypertension","score":0.9919999837875366},{"id":"https://openalex.org/keywords/multiple-organ-failure","display_name":"multiple organ failure","score":0.9599999785423279},{"id":"https://openalex.org/keywords/epilepsy-in-pregnancy","display_name":"epilepsy in pregnancy","score":0.753000020980835},{"id":"https://openalex.org/keywords/congenital-malformations","display_name":"congenital malformations","score":0.6019999980926514}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9112545251846313},{"id":"https://openalex.org/C2779253243","wikidata":"https://www.wikidata.org/wiki/Q410412","display_name":"Carbamazepine","level":3,"score":0.908095121383667},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.5362901091575623},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.4836929440498352},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.36673325300216675},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.07435178756713867},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000014","descriptor_name":"Abnormalities, Drug-Induced","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000927","descriptor_name":"Anticonvulsants","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D000927","descriptor_name":"Anticonvulsants","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D002220","descriptor_name":"Carbamazepine","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D002220","descriptor_name":"Carbamazepine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011248","descriptor_name":"Pregnancy Complications","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1136/bcr.05.2011.4243","doi":"https://doi.org/10.1136/bcr.05.2011.4243","is_oa":true,"landing_page_url":"https://doi.org/10.1136/bcr.05.2011.4243","pdf_url":"https://casereports.bmj.com/content/casereports/2011/bcr.05.2011.4243.full.pdf","source":{"id":"https://openalex.org/S141953298","display_name":"BMJ Case Reports","issn_l":"1757-790X","issn":["1757-790X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ Case Reports","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3524267","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4545117","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4545117","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4545117","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ Case Rep","raw_type":"Text"},{"id":"pmid:22687674","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22687674","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ case reports","raw_type":"Case Reports"}],"best_oa_location":{"id":"doi:10.1136/bcr.05.2011.4243","doi":"https://doi.org/10.1136/bcr.05.2011.4243","is_oa":true,"landing_page_url":"https://doi.org/10.1136/bcr.05.2011.4243","pdf_url":"https://casereports.bmj.com/content/casereports/2011/bcr.05.2011.4243.full.pdf","source":{"id":"https://openalex.org/S141953298","display_name":"BMJ Case Reports","issn_l":"1757-790X","issn":["1757-790X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ Case Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2099190822.pdf","grobid_xml":"https://content.openalex.org/works/W2099190822.grobid-xml"},"referenced_works_count":5,"referenced_works":["https://openalex.org/W2100387857","https://openalex.org/W2106628243","https://openalex.org/W2121891611","https://openalex.org/W2138732494","https://openalex.org/W2162933447"],"related_works":["https://openalex.org/W15443130","https://openalex.org/W2069279852","https://openalex.org/W1964566456","https://openalex.org/W2051047506","https://openalex.org/W2891201941","https://openalex.org/W2415932341","https://openalex.org/W4255365037","https://openalex.org/W2415437940","https://openalex.org/W2608269909","https://openalex.org/W2007013380"],"abstract_inverted_index":{"The":[0,19,51,88,117],"'foetal":[1,114],"carbamazepine":[2,37,115,122],"syndrome'":[3],"is":[4],"characterised":[5],"by":[6,55],"facial":[7,63],"dysmorphism":[8],"associated":[9],"to":[10,28,45,107,146],"cardiovascular,":[11],"nervous":[12],"system,":[13],"urinary":[14],"tract":[15],"and":[16,68,86,105],"skeletal":[17],"anomalies.":[18],"authors":[20],"present":[21],"the":[22,46,75,99,103,109,113,120,130,136,148],"case":[23,94],"of":[24,41,73,98,102,112,119,129,138,152],"a":[25,29,58],"neonate":[26],"born":[27,61],"33-year-old":[30],"epileptic":[31],"woman":[32],"treated":[33],"with":[34,135],"long":[35],"term":[36],"(CMZ)":[38],"therapy.":[39],"Four":[40],"her":[42],"pregnancies":[43],"exposed":[44],"drug":[47],"showed":[48],"bad":[49],"outcomes.":[50],"actual":[52],"pregnancy":[53],"ended":[54],"caesarean":[56],"section,":[57],"female":[59],"was":[60,90],"showing":[62],"dysmorphism,":[64],"hypoplasic":[65],"nails,":[66],"xyphosis":[67],"myelomeningocele.":[69],"After":[70],"7":[71],"days":[72],"birth,":[74],"infant":[76],"developed":[77],"severe":[78],"neutropenia,":[79],"moderate":[80],"pulmonary":[81],"hypertension,":[82],"multiple":[83],"organ":[84],"failure":[85],"died.":[87],"karyotype":[89],"46,":[91],"XX.":[92],"This":[93],"represents":[95],"an":[96],"example":[97],"wide":[100],"spectrum":[101],"syndrome":[104],"contributes":[106],"describe":[108],"clinical":[110,131],"profile":[111],"syndrome'.":[116],"delineation":[118],"foetal":[121],"syndrome's":[123],"phenotype":[124],"remains":[125],"incomplete,":[126],"since":[127],"many":[128],"manifestations":[132],"are":[133,144],"shared":[134],"effect":[137],"others":[139],"anticonvulsants,":[140],"therefore":[141],"further":[142],"studies":[143],"needed":[145],"determine":[147],"specific":[149],"noxious":[150],"effects":[151],"CMZ":[153],"in":[154],"utero.":[155]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2016-06-24T00:00:00"}