{"id":"https://openalex.org/W2099178442","doi":"https://doi.org/10.1177/0961203314520842","title":"Severe multiorganic flare of systemic lupus erythematosus successfully treated with rituximab and cyclophosphamide avoiding high doses of prednisone","display_name":"Severe multiorganic flare of systemic lupus erythematosus successfully treated with rituximab and cyclophosphamide avoiding high doses of prednisone","publication_year":2014,"publication_date":"2014-02-14","ids":{"openalex":"https://openalex.org/W2099178442","doi":"https://doi.org/10.1177/0961203314520842","mag":"2099178442","pmid":"https://pubmed.ncbi.nlm.nih.gov/24531426"},"language":"en","primary_location":{"id":"doi:10.1177/0961203314520842","doi":"https://doi.org/10.1177/0961203314520842","is_oa":false,"landing_page_url":"https://doi.org/10.1177/0961203314520842","pdf_url":null,"source":{"id":"https://openalex.org/S115920904","display_name":"Lupus","issn_l":"0961-2033","issn":["0961-2033","1477-0962"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lupus","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073716458","display_name":"Cristina Gonz\u00e1lez-Ech\u00e1varri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I169108374","display_name":"University of the Basque Country","ror":"https://ror.org/000xsnr85","country_code":"ES","type":"education","lineage":["https://openalex.org/I169108374"]},{"id":"https://openalex.org/I4210089430","display_name":"BioCruces Health research Institute","ror":"https://ror.org/0061s4v88","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I4210089430"]},{"id":"https://openalex.org/I4210137412","display_name":"Hospital de Cruces","ror":"https://ror.org/03nzegx43","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210125364","https://openalex.org/I4210137412"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"C Gonzalez-Echavarri","raw_affiliation_strings":["Autoimmune Diseases Research Unit, Department of Internal Medicine, Biocruces Health Research Institute, Hospital Universitario Cruces, University of The Basque Country, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Autoimmune Diseases Research Unit, Department of Internal Medicine, Biocruces Health Research Institute, Hospital Universitario Cruces, University of The Basque Country, Spain","institution_ids":["https://openalex.org/I169108374","https://openalex.org/I4210089430","https://openalex.org/I4210137412"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047057771","display_name":"Berta Pernas","orcid":"https://orcid.org/0000-0002-2061-3096","observed_orcids":["https://orcid.org/0000-0002-2061-3096"]},"institutions":[{"id":"https://openalex.org/I169108374","display_name":"University of the Basque Country","ror":"https://ror.org/000xsnr85","country_code":"ES","type":"education","lineage":["https://openalex.org/I169108374"]},{"id":"https://openalex.org/I4210089430","display_name":"BioCruces Health research Institute","ror":"https://ror.org/0061s4v88","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I4210089430"]},{"id":"https://openalex.org/I4210137412","display_name":"Hospital de Cruces","ror":"https://ror.org/03nzegx43","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210125364","https://openalex.org/I4210137412"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"B Pernas","raw_affiliation_strings":["Autoimmune Diseases Research Unit, Department of Internal Medicine, Biocruces Health Research Institute, Hospital Universitario Cruces, University of The Basque Country, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Autoimmune Diseases Research Unit, Department of Internal Medicine, Biocruces Health Research Institute, Hospital Universitario Cruces, University of The Basque Country, Spain","institution_ids":["https://openalex.org/I169108374","https://openalex.org/I4210089430","https://openalex.org/I4210137412"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000168500","display_name":"A. Ugarte","orcid":"https://orcid.org/0000-0002-1753-4186","observed_orcids":["https://orcid.org/0000-0002-1753-4186"]},"institutions":[{"id":"https://openalex.org/I169108374","display_name":"University of the Basque Country","ror":"https://ror.org/000xsnr85","country_code":"ES","type":"education","lineage":["https://openalex.org/I169108374"]},{"id":"https://openalex.org/I4210089430","display_name":"BioCruces Health research Institute","ror":"https://ror.org/0061s4v88","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I4210089430"]},{"id":"https://openalex.org/I4210137412","display_name":"Hospital de Cruces","ror":"https://ror.org/03nzegx43","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210125364","https://openalex.org/I4210137412"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"A Ugarte","raw_affiliation_strings":["Autoimmune Diseases Research Unit, Department of Internal Medicine, Biocruces Health Research Institute, Hospital Universitario Cruces, University of The Basque Country, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Autoimmune Diseases Research Unit, Department of Internal Medicine, Biocruces Health Research Institute, Hospital Universitario Cruces, University of The Basque Country, Spain","institution_ids":["https://openalex.org/I169108374","https://openalex.org/I4210089430","https://openalex.org/I4210137412"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5001878991","display_name":"Guillermo Ruiz\u2010Irastorza","orcid":"https://orcid.org/0000-0001-7788-1043","observed_orcids":["https://orcid.org/0000-0001-7788-1043"]},"institutions":[{"id":"https://openalex.org/I169108374","display_name":"University of the Basque Country","ror":"https://ror.org/000xsnr85","country_code":"ES","type":"education","lineage":["https://openalex.org/I169108374"]},{"id":"https://openalex.org/I4210089430","display_name":"BioCruces Health research Institute","ror":"https://ror.org/0061s4v88","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I4210089430"]},{"id":"https://openalex.org/I4210137412","display_name":"Hospital de Cruces","ror":"https://ror.org/03nzegx43","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210125364","https://openalex.org/I4210137412"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"G Ruiz-Irastorza","raw_affiliation_strings":["Autoimmune Diseases Research Unit, Department of Internal Medicine, Biocruces Health Research Institute, Hospital Universitario Cruces, University of The Basque Country, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Autoimmune Diseases Research Unit, Department of Internal Medicine, Biocruces Health Research Institute, Hospital Universitario Cruces, University of The Basque Country, Spain","institution_ids":["https://openalex.org/I169108374","https://openalex.org/I4210089430","https://openalex.org/I4210137412"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4150,"currency":"USD","value_usd":4150},"apc_paid":null,"fwci":1.8525,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.82979498,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"23","issue":"3","first_page":"323","last_page":"326"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10697","display_name":"Vasculitis and related conditions","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11330","display_name":"Systemic Sclerosis and Related Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/systemic-lupus-erythematosus","display_name":"systemic lupus erythematosus","score":0.9779999852180481},{"id":"https://openalex.org/keywords/lupus-flares","display_name":"lupus flares","score":0.8709999918937683},{"id":"https://openalex.org/keywords/diffuse-alveolar-hemorrhage","display_name":"diffuse alveolar hemorrhage","score":0.9580000042915344},{"id":"https://openalex.org/keywords/acute-respiratory-failure","display_name":"acute respiratory failure","score":0.871999979019165},{"id":"https://openalex.org/keywords/rituximab","display_name":"rituximab","score":0.9210000038146973},{"id":"https://openalex.org/keywords/cyclophosphamide","display_name":"cyclophosphamide","score":0.996999979019165},{"id":"https://openalex.org/keywords/methylprednisolone-pulse-therapy","display_name":"methylprednisolone pulse therapy","score":0.8529999852180481},{"id":"https://openalex.org/keywords/hydroxychloroquine","display_name":"hydroxychloroquine","score":0.9160000085830688},{"id":"https://openalex.org/keywords/azathioprine","display_name":"azathioprine","score":0.906000018119812},{"id":"https://openalex.org/keywords/corticosteroid-sparing-immunosuppression","display_name":"corticosteroid-sparing immunosuppression","score":0.6510000228881836}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9577552676200867},{"id":"https://openalex.org/C2779123688","wikidata":"https://www.wikidata.org/wiki/Q421094","display_name":"Hydroxychloroquine","level":5,"score":0.8470895886421204},{"id":"https://openalex.org/C2778720950","wikidata":"https://www.wikidata.org/wiki/Q424972","display_name":"Prednisone","level":2,"score":0.7619571685791016},{"id":"https://openalex.org/C2776755627","wikidata":"https://www.wikidata.org/wiki/Q408524","display_name":"Cyclophosphamide","level":3,"score":0.7477837800979614},{"id":"https://openalex.org/C2780653079","wikidata":"https://www.wikidata.org/wiki/Q412323","display_name":"Rituximab","level":3,"score":0.732783317565918},{"id":"https://openalex.org/C2776760755","wikidata":"https://www.wikidata.org/wiki/Q18939","display_name":"Azathioprine","level":3,"score":0.6429186463356018},{"id":"https://openalex.org/C2776715498","wikidata":"https://www.wikidata.org/wiki/Q11426176","display_name":"Prednisolone","level":2,"score":0.6173560619354248},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.493477463722229},{"id":"https://openalex.org/C2780372218","wikidata":"https://www.wikidata.org/wiki/Q417222","display_name":"Methylprednisolone","level":2,"score":0.4310756325721741},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.42743220925331116},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4209389388561249},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.15141361951828003},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.1193993091583252},{"id":"https://openalex.org/C2779338263","wikidata":"https://www.wikidata.org/wiki/Q208414","display_name":"Lymphoma","level":2,"score":0.10200002789497375},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.0},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000069283","descriptor_name":"Rituximab","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000208","descriptor_name":"Acute Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003520","descriptor_name":"Cyclophosphamide","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D003520","descriptor_name":"Cyclophosphamide","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D004359","descriptor_name":"Drug Therapy, Combination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006470","descriptor_name":"Hemorrhage","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007166","descriptor_name":"Immunosuppressive Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D007166","descriptor_name":"Immunosuppressive Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D010195","descriptor_name":"Pancreatitis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D010195","descriptor_name":"Pancreatitis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D011241","descriptor_name":"Prednisone","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D011241","descriptor_name":"Prednisone","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D012074","descriptor_name":"Remission Induction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012131","descriptor_name":"Respiratory Insufficiency","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D012131","descriptor_name":"Respiratory Insufficiency","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058846","descriptor_name":"Antibodies, Monoclonal, Murine-Derived","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D058846","descriptor_name":"Antibodies, Monoclonal, Murine-Derived","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1177/0961203314520842","doi":"https://doi.org/10.1177/0961203314520842","is_oa":false,"landing_page_url":"https://doi.org/10.1177/0961203314520842","pdf_url":null,"source":{"id":"https://openalex.org/S115920904","display_name":"Lupus","issn_l":"0961-2033","issn":["0961-2033","1477-0962"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lupus","raw_type":"journal-article"},{"id":"pmid:24531426","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24531426","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lupus","raw_type":"Case Reports"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1968279976","https://openalex.org/W1977224359","https://openalex.org/W2002097391","https://openalex.org/W2004135257","https://openalex.org/W2026355082","https://openalex.org/W2028398341","https://openalex.org/W2036917673","https://openalex.org/W2063467177","https://openalex.org/W2078378639","https://openalex.org/W2100144020","https://openalex.org/W2103509618","https://openalex.org/W2135514984","https://openalex.org/W2143645568","https://openalex.org/W2187344213"],"related_works":["https://openalex.org/W119665574","https://openalex.org/W2414955148","https://openalex.org/W2161559054","https://openalex.org/W2429361158","https://openalex.org/W1980400081","https://openalex.org/W2418450229","https://openalex.org/W2792815644","https://openalex.org/W2107172991","https://openalex.org/W1597457583","https://openalex.org/W2769007516"],"abstract_inverted_index":{"Both":[0],"acute":[1,45,223],"pancreatitis":[2,29,149,224],"and":[3,35,63,69,97,150,225,238],"diffuse":[4,51,151,226],"alveolar":[5,52,152,227],"haemorrhage":[6,153],"are":[7,154],"rare":[8,155],"conditions":[9,156],"associated":[10,141],"with":[11,23,27,39,67,79,88,105,142,166,219,233,241],"systemic":[12],"lupus":[13],"erythematosus":[14],"(SLE).":[15],"In":[16],"this":[17],"case":[18,121,214],"report,":[19],"a":[20,32,50,163,182,213,216],"23-year-old":[21],"female":[22],"SLE":[24,78,129,178],"was":[25,56,65,230],"diagnosed":[26],"lupus-associated":[28],"and,":[30],"within":[31],"few":[33],"days":[34],"despite":[36],"initial":[37,100,193],"therapy":[38],"pulse":[40,234],"methyl-prednisolone,":[41,235],"subsequently":[42],"suffered":[43],"an":[44,167],"respiratory":[46],"failure":[47],"due":[48],"to":[49,58,108,134,185],"haemorrhage.":[53],"The":[54],"patient":[55],"admitted":[57],"the":[59,74,114,117,192,206],"intensive":[60],"care":[61],"unit":[62],"treatment":[64,87],"intensified":[66],"cyclophosphamide":[68,92,237],"rituximab,":[70,239],"which":[71,138],"shortly":[72],"induced":[73],"complete":[75],"remission":[76],"of":[77,81,91,102,113,170,189,202,215,244],"resolution":[80],"both":[82],"clinical":[83,207],"conditions.":[84],"She":[85],"completed":[86],"six":[89],"pulses":[90],"followed":[93],"by":[94,158],"azathioprine,":[95],"hydroxychloroquine":[96],"prednisone":[98,190],"at":[99,171],"doses":[101,188,198,243],"20":[103],"mg/d":[104],"rapid":[106],"tapering":[107],"5":[109],"mg/d,":[110],"without":[111],"relapse":[112],"disease":[115],"during":[116],"following":[118],"year.":[119],"This":[120],"can":[122,161],"illustrate":[123],"that,":[124],"even":[125,204],"in":[126],"severe,":[127],"life-threatening":[128,164],"flares,":[130],"it":[131],"is":[132,181],"possible":[133],"avoid":[135],"high-dose":[136],"prednisone,":[137],"has":[139,209],"been":[140],"severe":[143,177],"side":[144],"effects,":[145],"including":[146],"infections.":[147],"Acute":[148],"caused":[157],"SLE.":[159],"DAH":[160],"be":[162],"complication,":[165],"early":[168],"mortality":[169],"least":[172],"50%.":[173],"When":[174],"facing":[175],"such":[176,196],"activity,":[179],"there":[180],"general":[183],"tendency":[184],"use":[186],"high":[187,197],"as":[191],"therapy,":[194],"maintaining":[195],"for":[199],"long":[200],"periods":[201],"time,":[203],"after":[205],"situation":[208],"subsided.":[210],"We":[211],"report":[212],"young":[217],"woman":[218],"SLE,":[220],"suffering":[221],"from":[222],"haemorrhage,":[228],"who":[229],"successfully":[231],"treated":[232],"hydroxychloroquine,":[236],"combined":[240],"medium":[242],"prednisone.":[245]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}