{"id":"https://openalex.org/W2099178172","doi":"https://doi.org/10.2337/diabetes.53.1.209","title":"Genetic Variation at the Adiponectin Locus and Risk of Type 2 Diabetes in Women","display_name":"Genetic Variation at the Adiponectin Locus and Risk of Type 2 Diabetes in Women","publication_year":2004,"publication_date":"2004-01-01","ids":{"openalex":"https://openalex.org/W2099178172","doi":"https://doi.org/10.2337/diabetes.53.1.209","mag":"2099178172","pmid":"https://pubmed.ncbi.nlm.nih.gov/14693717"},"language":"en","primary_location":{"id":"doi:10.2337/diabetes.53.1.209","doi":"https://doi.org/10.2337/diabetes.53.1.209","is_oa":false,"landing_page_url":"https://doi.org/10.2337/diabetes.53.1.209","pdf_url":null,"source":{"id":"https://openalex.org/S129060628","display_name":"Diabetes","issn_l":"0012-1797","issn":["0012-1797","1939-327X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320274","host_organization_name":"American Diabetes Association","host_organization_lineage":["https://openalex.org/P4310320274"],"host_organization_lineage_names":["American Diabetes Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056459536","display_name":"Frank B. Hu","orcid":"https://orcid.org/0000-0002-8233-6274","observed_orcids":["https://orcid.org/0000-0002-8233-6274","https://orcid.org/0000-0002-8412-2261"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Frank B. Hu","raw_affiliation_strings":["Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women\u2019s Hospital, Boston, Masachusetts","Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts","Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women\u2019s Hospital, Boston, Masachusetts","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021108498","display_name":"Alessandro Doria","orcid":"https://orcid.org/0000-0002-3830-4304","observed_orcids":["https://orcid.org/0000-0002-3830-4304"]},"institutions":[{"id":"https://openalex.org/I1293231726","display_name":"Joslin Diabetes Center","ror":"https://ror.org/0280a3n32","country_code":"US","type":"facility","lineage":["https://openalex.org/I1293231726"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alessandro Doria","raw_affiliation_strings":["Research Division, Joslin Diabetes Center, Department of Medicine, Harvard Medical School, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Division, Joslin Diabetes Center, Department of Medicine, Harvard Medical School, Boston, Massachusetts","institution_ids":["https://openalex.org/I1293231726","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011028097","display_name":"Tricia Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tricia Li","raw_affiliation_strings":["Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035126983","display_name":"James B. Meigs","orcid":"https://orcid.org/0000-0002-2439-2657","observed_orcids":["https://orcid.org/0000-0002-2439-2657"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James B. Meigs","raw_affiliation_strings":["General Medicine Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"General Medicine Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100607135","display_name":"Simin Liu","orcid":"https://orcid.org/0000-0003-2098-3844","observed_orcids":["https://orcid.org/0000-0003-2098-3844"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Simin Liu","raw_affiliation_strings":["Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts","Division of Preventive Medicine, Department of Medicine, Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Division of Preventive Medicine, Department of Medicine, Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, Massachusetts","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070554640","display_name":"Asl\u0131 Memi\u015fo\u011flu","orcid":"https://orcid.org/0000-0003-2579-9480","observed_orcids":["https://orcid.org/0000-0003-2579-9480"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Asli Memisoglu","raw_affiliation_strings":["Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":null,"display_name":"David Hunter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Hunter","raw_affiliation_strings":["Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women\u2019s Hospital, Boston, Masachusetts","Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts","Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women\u2019s Hospital, Boston, Masachusetts","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049411008","display_name":"JoAnn Elisabeth Manson","orcid":"https://orcid.org/0000-0002-9426-7595","observed_orcids":["https://orcid.org/0000-0002-9426-7595"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"JoAnn E. Manson","raw_affiliation_strings":["Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts","Division of Preventive Medicine, Department of Medicine, Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Division of Preventive Medicine, Department of Medicine, Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, Massachusetts","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":7.5824,"has_fulltext":false,"cited_by_count":103,"citation_normalized_percentile":{"value":0.97746925,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"53","issue":"1","first_page":"209","last_page":"213"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.9175000190734863,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.9175000190734863,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.06080000102519989,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11072","display_name":"Peroxisome Proliferator-Activated Receptors","score":0.005100000184029341,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adiponectin-gene","display_name":"adiponectin gene","score":0.9089999794960022},{"id":"https://openalex.org/keywords/type-2-diabetes-risk","display_name":"type 2 diabetes risk","score":0.9380000233650208},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.9760000109672546},{"id":"https://openalex.org/keywords/haplotype-tagging-snps","display_name":"haplotype-tagging SNPs","score":0.878000020980835},{"id":"https://openalex.org/keywords/gene-gene-interaction","display_name":"gene-gene interaction","score":0.8199999928474426},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.9869999885559082},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.7870000004768372},{"id":"https://openalex.org/keywords/women","display_name":"women","score":0.6200000047683716},{"id":"https://openalex.org/keywords/nurses-health-study","display_name":"Nurses' Health Study","score":0.9620000123977661}],"concepts":[{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.8271654844284058},{"id":"https://openalex.org/C2776782570","wikidata":"https://www.wikidata.org/wiki/Q357439","display_name":"Adiponectin","level":4,"score":0.8180211186408997},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.7934287786483765},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.7627658843994141},{"id":"https://openalex.org/C197754878","wikidata":"https://www.wikidata.org/wiki/Q80711","display_name":"Haplotype","level":4,"score":0.7176339626312256},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5740389823913574},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.5708580017089844},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.5527898669242859},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.49624496698379517},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.48842042684555054},{"id":"https://openalex.org/C37463918","wikidata":"https://www.wikidata.org/wiki/Q387981","display_name":"Allele frequency","level":4,"score":0.42456528544425964},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.4192041754722595},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.41231152415275574},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.36671000719070435},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3557104468345642},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.20670366287231445}],"mesh":[{"descriptor_ui":"D000428","descriptor_name":"Alcohol Drinking","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012907","descriptor_name":"Smoking","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015992","descriptor_name":"Body Mass Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018160","descriptor_name":"Receptors, Cytoplasmic and Nuclear","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D036341","descriptor_name":"Intercellular Signaling Peptides and Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D052242","descriptor_name":"Adiponectin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.2337/diabetes.53.1.209","doi":"https://doi.org/10.2337/diabetes.53.1.209","is_oa":false,"landing_page_url":"https://doi.org/10.2337/diabetes.53.1.209","pdf_url":null,"source":{"id":"https://openalex.org/S129060628","display_name":"Diabetes","issn_l":"0012-1797","issn":["0012-1797","1939-327X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320274","host_organization_name":"American Diabetes Association","host_organization_lineage":["https://openalex.org/P4310320274"],"host_organization_lineage_names":["American Diabetes Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes","raw_type":"journal-article"},{"id":"pmid:14693717","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14693717","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.939.6579","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.939.6579","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://diabetes.diabetesjournals.org/content/diabetes/53/1/209.full.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G2979075132","display_name":"Biochemical and Genetic Markers of Type 2 Diabetes Risk","funder_award_id":"R01DK058845","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G3965309116","display_name":"Dietary and Hormonal Determinants of Cancer in Women","funder_award_id":"P01CA087969","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G6983023206","display_name":"Search for new MODY genes and molecular studies of their function in beta cells","funder_award_id":"R01DK055523","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320306089","display_name":"American Diabetes Association","ror":"https://ror.org/04f6cgz95"},{"id":"https://openalex.org/F4320306230","display_name":"American Heart Association","ror":"https://ror.org/013kjyp64"},{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1485161311","https://openalex.org/W2006174703","https://openalex.org/W2015899437","https://openalex.org/W2065697164","https://openalex.org/W2068491028","https://openalex.org/W2091759162","https://openalex.org/W2106550052","https://openalex.org/W2120462461","https://openalex.org/W2130670158","https://openalex.org/W2131702141","https://openalex.org/W2138334499","https://openalex.org/W2147921895","https://openalex.org/W2159829835","https://openalex.org/W2320856221","https://openalex.org/W2345903479","https://openalex.org/W4233562854","https://openalex.org/W4243841175"],"related_works":["https://openalex.org/W7096563244","https://openalex.org/W2385422971","https://openalex.org/W2999758554","https://openalex.org/W2407884685","https://openalex.org/W2319148348","https://openalex.org/W2061793689","https://openalex.org/W2371800065","https://openalex.org/W2112652696","https://openalex.org/W2150455199","https://openalex.org/W3006860480"],"abstract_inverted_index":{"Previous":[0],"data":[1,184],"suggesting":[2],"that":[3],"polymorphisms":[4,31],"in":[5,33,74,86,210],"the":[6,23,34,49,75,92,96,107,124,138,165,190],"adiponectin":[7,35,191],"gene":[8,36],"were":[9],"associated":[10,112,143],"with":[11,113,123,144,150,164],"insulin":[12],"resistance":[13],"or":[14,88,174,197],"type":[15,52,66],"2":[16,53,67],"diabetes":[17,54,68,104,118,145],"have":[18],"been":[19],"inconsistent.":[20],"We":[21],"assessed":[22],"relationship":[24],"between":[25,95,189],"five":[26,93],"common":[27],"haplotype-tagging":[28],"single":[29],"nucleotide":[30],"(SNPs)":[32],"(-11365C>G,":[37],"-4034A>C,":[38],"-3964A>G,":[39],"+45T>G,":[40],"and":[41,48,69,98,193,206],"+276G>T),":[42],"haplotypes":[43],"defined":[44],"by":[45,55],"these":[46,200],"SNPs,":[47],"risk":[50,105,116,146],"of":[51,61,65,117],"conducting":[56],"a":[57,114,186],"nested":[58],"case-control":[59],"study":[60],"642":[62],"incident":[63],"cases":[64],"995":[70],"matching":[71],"control":[72,99],"subjects":[73,149,177],"Nurses'":[76],"Health":[77],"Study.":[78],"Overall,":[79],"we":[80],"did":[81],"not":[82],"observe":[83],"significant":[84],"differences":[85],"genotype":[87,110,126,140,167,192,196],"allele":[89,158],"frequencies":[90],"for":[91,103],"SNPs":[94],"case":[97],"subjects.":[100],"After":[101],"adjustment":[102],"factors,":[106],"-4034":[108],"C/C":[109],"was":[111,141],"reduced":[115],"(odds":[119],"ratio":[120],"[OR]":[121],"compared":[122],"A/A":[125],"=":[127,133,168,172,181],"0.70,":[128],"95%":[129],"CI":[130],"0.50-0.99,":[131],"P":[132,171,180],"0.04).":[134],"In":[135],"subgroup":[136],"analyses,":[137],"+276":[139,161],"significantly":[142],"only":[147],"among":[148,175],"peroxisome":[151],"proliferator-activated":[152],"receptor-gamma":[153],"(PPAR":[154],"gamma)":[155],"variant":[156],"12Ala":[157],"(OR":[159],"comparing":[160],"T":[162],"alleles":[163],"G/G":[166],"1.69,":[169],"1.04-2.75,":[170],"0.035)":[173],"obese":[176],"(1.46,":[178],"1.03-2.08,":[179],"0.03).":[182],"These":[183],"suggest":[185],"potential":[187],"interaction":[188],"PPAR":[194],"gamma":[195],"obesity,":[198],"but":[199],"analyses":[201],"should":[202],"be":[203],"considered":[204],"exploratory":[205],"require":[207],"further":[208],"investigation":[209],"larger":[211],"studies.":[212]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":7}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}