{"id":"https://openalex.org/W20987123","doi":null,"title":"Vascular remodeling: mechanisms and implications.","display_name":"Vascular remodeling: mechanisms and implications.","publication_year":1993,"publication_date":"1993-01-01","ids":{"openalex":"https://openalex.org/W20987123","mag":"20987123","pmid":"https://pubmed.ncbi.nlm.nih.gov/7681124"},"language":"en","primary_location":{"id":"pmid:7681124","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7681124","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of cardiovascular pharmacology","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090663343","display_name":"Victor J. Dzau","orcid":"https://orcid.org/0000-0002-8280-519X","observed_orcids":["https://orcid.org/0000-0002-8280-519X"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"V J Dzau","raw_affiliation_strings":["Division of Cardiovascular Medicine, Falk Cardiovascular Research Center, Stanford University Medical Center, California 94305-5246"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular Medicine, Falk Cardiovascular Research Center, Stanford University Medical Center, California 94305-5246","institution_ids":["https://openalex.org/I4210137306"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112742186","display_name":"Gary H. Gibbons","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G H Gibbons","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":5.3109,"has_fulltext":false,"cited_by_count":99,"citation_normalized_percentile":{"value":0.95768229,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"21 Suppl 1","issue":null,"first_page":"S1","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.30660000443458557,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.30660000443458557,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14486","display_name":"Cardiovascular, Neuropeptides, and Oxidative Stress Research","score":0.1386999934911728,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.08860000222921371,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vascular-remodeling","display_name":"vascular remodeling","score":1.0},{"id":"https://openalex.org/keywords/blood-vessel-structure","display_name":"blood vessel structure","score":0.7730000019073486},{"id":"https://openalex.org/keywords/hemodynamic-adaptation","display_name":"hemodynamic adaptation","score":0.7940000295639038},{"id":"https://openalex.org/keywords/humoral-factors","display_name":"humoral factors","score":0.9150000214576721},{"id":"https://openalex.org/keywords/vascular-disease","display_name":"vascular disease","score":0.8009999990463257},{"id":"https://openalex.org/keywords/circulatory-diseases","display_name":"circulatory diseases","score":0.9490000009536743},{"id":"https://openalex.org/keywords/vascular-tone","display_name":"vascular tone","score":0.5490000247955322}],"concepts":[{"id":"https://openalex.org/C72859922","wikidata":"https://www.wikidata.org/wiki/Q11068","display_name":"Circulatory system","level":2,"score":0.5923476815223694},{"id":"https://openalex.org/C2994227525","wikidata":"https://www.wikidata.org/wiki/Q456026","display_name":"Vascular tone","level":3,"score":0.518518328666687},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5054850578308105},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.4945654571056366},{"id":"https://openalex.org/C2777663904","wikidata":"https://www.wikidata.org/wiki/Q988343","display_name":"Blood vessel","level":2,"score":0.46052059531211853},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.324019193649292},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2791295051574707},{"id":"https://openalex.org/C120770815","wikidata":"https://www.wikidata.org/wiki/Q14859627","display_name":"Vasodilation","level":2,"score":0.08466082811355591}],"mesh":[{"descriptor_ui":"D001808","descriptor_name":"Blood Vessels","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D001808","descriptor_name":"Blood Vessels","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001808","descriptor_name":"Blood Vessels","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D003326","descriptor_name":"Coronary Circulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005109","descriptor_name":"Extracellular Matrix","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009131","descriptor_name":"Muscle, Smooth, Vascular","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009131","descriptor_name":"Muscle, Smooth, Vascular","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:7681124","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7681124","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of cardiovascular pharmacology","raw_type":"Journal Article"},{"id":"mag:20987123","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7681124","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8048999905586243}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1936313808","display_name":"ANP RECEPTOR SUBTYPE EXPRESSION DURING VASCULAR GROWTH","funder_award_id":"R01HL042663","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G358260634","display_name":"EC RENIN ANGIOTENSIN INTERACTION IN VASCULAR DISEASE","funder_award_id":"R01HL035252","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2329961439","https://openalex.org/W2284520507","https://openalex.org/W7096778584","https://openalex.org/W2054970268","https://openalex.org/W2064693920","https://openalex.org/W2939928497","https://openalex.org/W2403056852","https://openalex.org/W2009372345","https://openalex.org/W2567144856","https://openalex.org/W2001667321"],"abstract_inverted_index":{"It":[0,51],"is":[1,18,31,52],"now":[2],"recognized":[3],"that,":[4],"in":[5,25,41,44,57,62,93,115],"addition":[6],"to":[7,10,27,59,74,98,108],"being":[8],"able":[9],"change":[11,43],"its":[12,22],"tone":[13],"acutely,":[14],"the":[15,45,48,75,91,100],"blood":[16,49],"vessel":[17],"capable":[19],"of":[20,47,77,85,90,104,121],"altering":[21],"structure":[23],"chronically":[24],"response":[26,58],"specific":[28],"conditions.":[29],"This":[30],"mediated":[32],"by":[33],"vascular":[34,70,78,105],"remodeling,":[35],"an":[36,54],"active":[37],"process":[38,56],"that":[39],"results":[40],"a":[42,110],"geometry":[46],"vessel.":[50],"usually":[53],"adaptive":[55],"chronic":[60],"changes":[61],"hemodynamic":[63],"conditions":[64],"and/or":[65],"humoral":[66],"factors.":[67],"Subsequently,":[68],"however,":[69],"remodeling":[71,106],"may":[72],"contribute":[73],"pathophysiology":[76],"diseases":[79],"and":[80,89,102,107,118],"circulatory":[81],"disorders.":[82],"The":[83],"purposes":[84],"this":[86,94,116],"overview":[87],"article":[88],"manuscripts":[92],"journal":[95],"supplement":[96],"are":[97],"review":[99],"pathobiology":[101],"consequences":[103],"provide":[109],"framework":[111],"for":[112],"future":[113],"research":[114],"emerging":[117],"important":[119],"field":[120],"cardiovascular":[122],"investigation.":[123]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-06-24T00:00:00"}