{"id":"https://openalex.org/W2098650593","doi":"https://doi.org/10.1016/j.biomag.2010.09.002","title":"Neuroendocrine axes function in healthy aging: Evaluation of predictive and manipulable blood serum indexes","display_name":"Neuroendocrine axes function in healthy aging: Evaluation of predictive and manipulable blood serum indexes","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W2098650593","doi":"https://doi.org/10.1016/j.biomag.2010.09.002","mag":"2098650593"},"language":"en","primary_location":{"id":"doi:10.1016/j.biomag.2010.09.002","doi":"https://doi.org/10.1016/j.biomag.2010.09.002","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.biomag.2010.09.002","pdf_url":null,"source":{"id":"https://openalex.org/S2898381501","display_name":"Biomedicine & Aging Pathology","issn_l":"2210-5220","issn":["2210-5220"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedicine &amp; Aging Pathology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030238472","display_name":"Gianluigi Mazzoccoli","orcid":"https://orcid.org/0000-0003-3535-7635","observed_orcids":["https://orcid.org/0000-0003-3535-7635"]},"institutions":[{"id":"https://openalex.org/I2800188116","display_name":"Casa Sollievo della Sofferenza","ror":"https://ror.org/00md77g41","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2800188116","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"G. Mazzoccoli","raw_affiliation_strings":["Department of Internal Medicine and Chronobiology Unit, Scientific Institute and Regional General Hospital \u00ab\u00a0Casa Sollievo della Sofferenza\u00a0\u00bb, Cappuccini Avenue, 71013 S.Giovanni Rotondo (FG), Italy","Department of Internal Medicine and Chronobiology Unit, Scientific Institute and Regional General Hospital 'Casa Sollievo della Sofferenza', Cappuccini Avenue, 71013 S. Giovanni Rotondo (FG), Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine and Chronobiology Unit, Scientific Institute and Regional General Hospital \u00ab\u00a0Casa Sollievo della Sofferenza\u00a0\u00bb, Cappuccini Avenue, 71013 S.Giovanni Rotondo (FG), Italy","institution_ids":["https://openalex.org/I2800188116"]},{"raw_affiliation_string":"Department of Internal Medicine and Chronobiology Unit, Scientific Institute and Regional General Hospital 'Casa Sollievo della Sofferenza', Cappuccini Avenue, 71013 S. Giovanni Rotondo (FG), Italy","institution_ids":["https://openalex.org/I2800188116"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105508902","display_name":"Gianluigi Vendemiale","orcid":"https://orcid.org/0000-0002-7951-0219","observed_orcids":["https://orcid.org/0000-0002-7951-0219"]},"institutions":[{"id":"https://openalex.org/I106296451","display_name":"University of Foggia","ror":"https://ror.org/01xtv3204","country_code":"IT","type":"education","lineage":["https://openalex.org/I106296451"]},{"id":"https://openalex.org/I2800188116","display_name":"Casa Sollievo della Sofferenza","ror":"https://ror.org/00md77g41","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2800188116","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"G. Vendemiale","raw_affiliation_strings":["Department of Internal Medicine and Chronobiology Unit, Scientific Institute and Regional General Hospital \u00ab\u00a0Casa Sollievo della Sofferenza\u00a0\u00bb, Cappuccini Avenue, 71013 S.Giovanni Rotondo (FG), Italy","Geriatrics Unit, Department of Medical Sciences, University of Foggia, Foggia (FG), Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine and Chronobiology Unit, Scientific Institute and Regional General Hospital \u00ab\u00a0Casa Sollievo della Sofferenza\u00a0\u00bb, Cappuccini Avenue, 71013 S.Giovanni Rotondo (FG), Italy","institution_ids":["https://openalex.org/I2800188116"]},{"raw_affiliation_string":"Geriatrics Unit, Department of Medical Sciences, University of Foggia, Foggia (FG), Italy","institution_ids":["https://openalex.org/I106296451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062775755","display_name":"Matilde Inglese","orcid":"https://orcid.org/0000-0002-9610-0297","observed_orcids":["https://orcid.org/0000-0002-9610-0297"]},"institutions":[{"id":"https://openalex.org/I2800188116","display_name":"Casa Sollievo della Sofferenza","ror":"https://ror.org/00md77g41","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2800188116","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"M. Inglese","raw_affiliation_strings":["Department of Internal Medicine and Chronobiology Unit, Scientific Institute and Regional General Hospital \u00ab\u00a0Casa Sollievo della Sofferenza\u00a0\u00bb, Cappuccini Avenue, 71013 S.Giovanni Rotondo (FG), Italy","Department of Internal Medicine and Chronobiology Unit, Scientific Institute and Regional General Hospital 'Casa Sollievo della Sofferenza', Cappuccini Avenue, 71013 S. Giovanni Rotondo (FG), Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine and Chronobiology Unit, Scientific Institute and Regional General Hospital \u00ab\u00a0Casa Sollievo della Sofferenza\u00a0\u00bb, Cappuccini Avenue, 71013 S.Giovanni Rotondo (FG), Italy","institution_ids":["https://openalex.org/I2800188116"]},{"raw_affiliation_string":"Department of Internal Medicine and Chronobiology Unit, Scientific Institute and Regional General Hospital 'Casa Sollievo della Sofferenza', Cappuccini Avenue, 71013 S. Giovanni Rotondo (FG), Italy","institution_ids":["https://openalex.org/I2800188116"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112718907","display_name":"A. De Cata","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800188116","display_name":"Casa Sollievo della Sofferenza","ror":"https://ror.org/00md77g41","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2800188116","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A. De Cata","raw_affiliation_strings":["Department of Internal Medicine and Chronobiology Unit, Scientific Institute and Regional General Hospital \u00ab\u00a0Casa Sollievo della Sofferenza\u00a0\u00bb, Cappuccini Avenue, 71013 S.Giovanni Rotondo (FG), Italy","Department of Internal Medicine and Chronobiology Unit, Scientific Institute and Regional General Hospital 'Casa Sollievo della Sofferenza', Cappuccini Avenue, 71013 S. Giovanni Rotondo (FG), Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine and Chronobiology Unit, Scientific Institute and Regional General Hospital \u00ab\u00a0Casa Sollievo della Sofferenza\u00a0\u00bb, Cappuccini Avenue, 71013 S.Giovanni Rotondo (FG), Italy","institution_ids":["https://openalex.org/I2800188116"]},{"raw_affiliation_string":"Department of Internal Medicine and Chronobiology Unit, Scientific Institute and Regional General Hospital 'Casa Sollievo della Sofferenza', Cappuccini Avenue, 71013 S. Giovanni Rotondo (FG), Italy","institution_ids":["https://openalex.org/I2800188116"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063023531","display_name":"Ada Piepoli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800188116","display_name":"Casa Sollievo della Sofferenza","ror":"https://ror.org/00md77g41","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2800188116","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A. Piepoli","raw_affiliation_strings":["Research Laboratory of Gastroenterology and Oncology, Scientific Institute and Regional General Hospital \u00ab\u00a0Casa Sollievo della Sofferenza\u00a0\u00bb, S.Giovanni Rotondo (FG), Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Laboratory of Gastroenterology and Oncology, Scientific Institute and Regional General Hospital \u00ab\u00a0Casa Sollievo della Sofferenza\u00a0\u00bb, S.Giovanni Rotondo (FG), Italy","institution_ids":["https://openalex.org/I2800188116"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085445167","display_name":"Valerio Pazienza","orcid":"https://orcid.org/0000-0002-3492-1153","observed_orcids":["https://orcid.org/0000-0002-3492-1153"]},"institutions":[{"id":"https://openalex.org/I2800188116","display_name":"Casa Sollievo della Sofferenza","ror":"https://ror.org/00md77g41","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2800188116","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"V. Pazienza","raw_affiliation_strings":["Research Laboratory of Gastroenterology and Oncology, Scientific Institute and Regional General Hospital \u00ab\u00a0Casa Sollievo della Sofferenza\u00a0\u00bb, S.Giovanni Rotondo (FG), Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Laboratory of Gastroenterology and Oncology, Scientific Institute and Regional General Hospital \u00ab\u00a0Casa Sollievo della Sofferenza\u00a0\u00bb, S.Giovanni Rotondo (FG), Italy","institution_ids":["https://openalex.org/I2800188116"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036881691","display_name":"Lucia Anna Muscarella","orcid":"https://orcid.org/0000-0002-1866-8151","observed_orcids":["https://orcid.org/0000-0002-1866-8151"]},"institutions":[{"id":"https://openalex.org/I2800188116","display_name":"Casa Sollievo della Sofferenza","ror":"https://ror.org/00md77g41","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2800188116","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"L.A. Muscarella","raw_affiliation_strings":["Research Laboratory of Gastroenterology and Oncology, Scientific Institute and Regional General Hospital \u00ab\u00a0Casa Sollievo della Sofferenza\u00a0\u00bb, S.Giovanni Rotondo (FG), Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Laboratory of Gastroenterology and Oncology, Scientific Institute and Regional General Hospital \u00ab\u00a0Casa Sollievo della Sofferenza\u00a0\u00bb, S.Giovanni Rotondo (FG), Italy","institution_ids":["https://openalex.org/I2800188116"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082642205","display_name":"Roberto Tarquini","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I45084792","display_name":"University of Florence","ror":"https://ror.org/04jr1s763","country_code":"IT","type":"education","lineage":["https://openalex.org/I45084792"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"R. Tarquini","raw_affiliation_strings":["Department of Internal Medicine, University of Florence, Florence (FI), Italy","Department of Internal Medicine, University of Florence,Florence (FI),Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, University of Florence, Florence (FI), Italy","institution_ids":["https://openalex.org/I45084792"]},{"raw_affiliation_string":"Department of Internal Medicine, University of Florence,Florence (FI),Italy","institution_ids":["https://openalex.org/I45084792"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5030238472"],"corresponding_institution_ids":["https://openalex.org/I2800188116"],"apc_list":null,"apc_paid":null,"fwci":0.297,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.57395598,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"1","issue":"1","first_page":"16","last_page":"21"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.9282000064849854,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.9282000064849854,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10748","display_name":"Growth Hormone and Insulin-like Growth Factors","score":0.026399999856948853,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.01140000019222498,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/healthy-aging","display_name":"healthy aging","score":0.9850000143051147},{"id":"https://openalex.org/keywords/circadian-rhythm","display_name":"circadian rhythm","score":0.7699999809265137},{"id":"https://openalex.org/keywords/melatonin","display_name":"melatonin","score":0.6959999799728394},{"id":"https://openalex.org/keywords/cortisol","display_name":"cortisol","score":1.0},{"id":"https://openalex.org/keywords/thyrotropin-releasing-hormone","display_name":"thyrotropin-releasing hormone","score":0.871999979019165},{"id":"https://openalex.org/keywords/thyroid-stimulating-hormone","display_name":"thyroid-stimulating hormone","score":0.8529999852180481},{"id":"https://openalex.org/keywords/free-thyroxine","display_name":"free thyroxine","score":0.9449999928474426},{"id":"https://openalex.org/keywords/growth-hormone","display_name":"growth hormone","score":0.9980000257492065},{"id":"https://openalex.org/keywords/insulin-like-growth-factor-i","display_name":"insulin-like growth factor I","score":0.8289999961853027},{"id":"https://openalex.org/keywords/mesor","display_name":"mesor","score":0.753000020980835},{"id":"https://openalex.org/keywords/acrophase","display_name":"acrophase","score":0.8600000143051147},{"id":"https://openalex.org/keywords/photoperiod","display_name":"photoperiod","score":0.7919999957084656},{"id":"https://openalex.org/keywords/healthy-older-adults","display_name":"healthy older adults","score":0.45100000500679016}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8579326272010803},{"id":"https://openalex.org/C2778182776","wikidata":"https://www.wikidata.org/wiki/Q180912","display_name":"Melatonin","level":2,"score":0.8520479202270508},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.8340110778808594},{"id":"https://openalex.org/C121446783","wikidata":"https://www.wikidata.org/wiki/Q208353","display_name":"Circadian rhythm","level":2,"score":0.6147866249084473},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.562251627445221},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.5133385062217712}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.biomag.2010.09.002","doi":"https://doi.org/10.1016/j.biomag.2010.09.002","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.biomag.2010.09.002","pdf_url":null,"source":{"id":"https://openalex.org/S2898381501","display_name":"Biomedicine & Aging Pathology","issn_l":"2210-5220","issn":["2210-5220"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedicine &amp; Aging Pathology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.699999988079071}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W14082013","https://openalex.org/W1964005327","https://openalex.org/W1966396750","https://openalex.org/W1978916721","https://openalex.org/W1983346465","https://openalex.org/W1986300150","https://openalex.org/W1996400421","https://openalex.org/W2022097084","https://openalex.org/W2028490033","https://openalex.org/W2029041205","https://openalex.org/W2042626693","https://openalex.org/W2066861741","https://openalex.org/W2068203152","https://openalex.org/W2069869036","https://openalex.org/W2090123343","https://openalex.org/W2093047158","https://openalex.org/W2096971852","https://openalex.org/W2097958456","https://openalex.org/W2100538764","https://openalex.org/W2103328299","https://openalex.org/W2114824887","https://openalex.org/W2117123178","https://openalex.org/W2130237579","https://openalex.org/W2144121151","https://openalex.org/W2146271348","https://openalex.org/W2148113299","https://openalex.org/W2166021020","https://openalex.org/W2170344274","https://openalex.org/W2323516874","https://openalex.org/W2407151642"],"related_works":["https://openalex.org/W2234554388","https://openalex.org/W2049560229","https://openalex.org/W2051156726","https://openalex.org/W2337544336","https://openalex.org/W2055969274","https://openalex.org/W2164865501","https://openalex.org/W2043982245","https://openalex.org/W1776470977","https://openalex.org/W6991601022","https://openalex.org/W2036931212"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-06-24T00:00:00"}
