{"id":"https://openalex.org/W2098646490","doi":"https://doi.org/10.1200/jco.2006.07.6356","title":"A Prospective Study of Plasma Prolactin Concentrations and Risk of Premenopausal and Postmenopausal Breast Cancer","display_name":"A Prospective Study of Plasma Prolactin Concentrations and Risk of Premenopausal and Postmenopausal Breast Cancer","publication_year":2007,"publication_date":"2007-03-20","ids":{"openalex":"https://openalex.org/W2098646490","doi":"https://doi.org/10.1200/jco.2006.07.6356","mag":"2098646490","pmid":"https://pubmed.ncbi.nlm.nih.gov/17372279"},"language":"en","primary_location":{"id":"doi:10.1200/jco.2006.07.6356","doi":"https://doi.org/10.1200/jco.2006.07.6356","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2006.07.6356","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054091966","display_name":"Shelley S. Tworoger","orcid":"https://orcid.org/0000-0002-6986-7046","observed_orcids":["https://orcid.org/0000-0002-6986-7046"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shelley S. Tworoger","raw_affiliation_strings":["From the Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School; Department of Epidemiology, Harvard School of Public Health; Reproductive Endocrinology Unit Laboratory, Massachusetts General Hospital, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School; Department of Epidemiology, Harvard School of Public Health; Reproductive Endocrinology Unit Laboratory, Massachusetts General Hospital, Boston, MA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014551852","display_name":"A. Heather Eliassen","orcid":"https://orcid.org/0000-0002-3961-6609","observed_orcids":["https://orcid.org/0000-0002-3961-6609"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Heather Eliassen","raw_affiliation_strings":["From the Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School; Department of Epidemiology, Harvard School of Public Health; Reproductive Endocrinology Unit Laboratory, Massachusetts General Hospital, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School; Department of Epidemiology, Harvard School of Public Health; Reproductive Endocrinology Unit Laboratory, Massachusetts General Hospital, Boston, MA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021696245","display_name":"Patrick M. Sluss","orcid":"https://orcid.org/0000-0003-2536-134X","observed_orcids":["https://orcid.org/0000-0003-2536-134X"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patrick Sluss","raw_affiliation_strings":["From the Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School; Department of Epidemiology, Harvard School of Public Health; Reproductive Endocrinology Unit Laboratory, Massachusetts General Hospital, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School; Department of Epidemiology, Harvard School of Public Health; Reproductive Endocrinology Unit Laboratory, Massachusetts General Hospital, Boston, MA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008373933","display_name":"Susan E. Hankinson","orcid":"https://orcid.org/0000-0001-9155-3767","observed_orcids":["https://orcid.org/0000-0001-9155-3767"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan E. Hankinson","raw_affiliation_strings":["From the Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School; Department of Epidemiology, Harvard School of Public Health; Reproductive Endocrinology Unit Laboratory, Massachusetts General Hospital, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School; Department of Epidemiology, Harvard School of Public Health; Reproductive Endocrinology Unit Laboratory, Massachusetts General Hospital, Boston, MA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":12.1792,"has_fulltext":false,"cited_by_count":215,"citation_normalized_percentile":{"value":0.99193376,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"25","issue":"12","first_page":"1482","last_page":"1488"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12103","display_name":"Cancer Risks and Factors","score":0.9164999723434448,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12103","display_name":"Cancer Risks and Factors","score":0.9164999723434448,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10748","display_name":"Growth Hormone and Insulin-like Growth Factors","score":0.031300000846385956,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.02850000001490116,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prolactin","display_name":"prolactin","score":0.9980000257492065},{"id":"https://openalex.org/keywords/breast-cancer-risk","display_name":"breast cancer risk","score":0.9710000157356262},{"id":"https://openalex.org/keywords/premenopausal-women","display_name":"premenopausal women","score":0.8970000147819519},{"id":"https://openalex.org/keywords/postmenopausal-women","display_name":"postmenopausal women","score":0.9890000224113464},{"id":"https://openalex.org/keywords/estrogen-receptor-positive-tumors","display_name":"estrogen receptor-positive tumors","score":0.8949999809265137},{"id":"https://openalex.org/keywords/menopausal-status","display_name":"menopausal status","score":0.8529999852180481},{"id":"https://openalex.org/keywords/plasma-prolactin-concentration","display_name":"plasma prolactin concentration","score":0.6579999923706055},{"id":"https://openalex.org/keywords/breast-cancer-etiology","display_name":"breast cancer etiology","score":0.8270000219345093},{"id":"https://openalex.org/keywords/nurses-health-study","display_name":"Nurses' Health Study","score":0.9539999961853027}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9386038780212402},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.7666553258895874},{"id":"https://openalex.org/C68443243","wikidata":"https://www.wikidata.org/wiki/Q2786686","display_name":"Quartile","level":3,"score":0.6583424210548401},{"id":"https://openalex.org/C82789193","wikidata":"https://www.wikidata.org/wiki/Q2142611","display_name":"Relative risk","level":3,"score":0.6219172477722168},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.6159653067588806},{"id":"https://openalex.org/C148759681","wikidata":"https://www.wikidata.org/wiki/Q2005375","display_name":"Nurses' Health Study","level":3,"score":0.6040595769882202},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5345377922058105},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.5247371792793274},{"id":"https://openalex.org/C2779064019","wikidata":"https://www.wikidata.org/wiki/Q66590068","display_name":"Prolactin","level":3,"score":0.4980611801147461},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.4955340623855591},{"id":"https://openalex.org/C2778562196","wikidata":"https://www.wikidata.org/wiki/Q177708","display_name":"Menopause","level":2,"score":0.4763094186782837},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.47381487488746643},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3741484582424164},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.23982417583465576},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.2244214117527008}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011336","descriptor_name":"Probability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011388","descriptor_name":"Prolactin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D015994","descriptor_name":"Incidence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016001","descriptor_name":"Confidence Intervals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016015","descriptor_name":"Logistic Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016019","descriptor_name":"Survival Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017677","descriptor_name":"Age Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017697","descriptor_name":"Premenopause","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D017698","descriptor_name":"Postmenopause","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D018570","descriptor_name":"Risk Assessment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1200/jco.2006.07.6356","doi":"https://doi.org/10.1200/jco.2006.07.6356","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2006.07.6356","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},{"id":"pmid:17372279","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17372279","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical oncology : official journal of the American Society of Clinical Oncology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[{"id":"https://openalex.org/G151562090","display_name":null,"funder_award_id":"CA-49449","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G3602225402","display_name":null,"funder_award_id":"CA67262","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G3965309116","display_name":"Dietary and Hormonal Determinants of Cancer in Women","funder_award_id":"P01CA087969","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G7141723403","display_name":"Nutritional Epidemiology of Cancer Education and Career Development Program","funder_award_id":"R25CA098566","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G756856000","display_name":"Risk Factors for Breast Cancer in Younger Nurses","funder_award_id":"R01CA050385","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G7880683311","display_name":"Dana-Farber/Harvard SPORE in Breast Cancer","funder_award_id":"P50CA089393","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W1511930757","https://openalex.org/W1525217135","https://openalex.org/W1878492789","https://openalex.org/W1918579068","https://openalex.org/W1951670987","https://openalex.org/W1952381273","https://openalex.org/W1969456163","https://openalex.org/W1973948212","https://openalex.org/W1991186704","https://openalex.org/W1995797698","https://openalex.org/W1999070019","https://openalex.org/W2004914398","https://openalex.org/W2015220984","https://openalex.org/W2018280013","https://openalex.org/W2018405736","https://openalex.org/W2023523424","https://openalex.org/W2032516148","https://openalex.org/W2034072513","https://openalex.org/W2042464257","https://openalex.org/W2042504507","https://openalex.org/W2047909114","https://openalex.org/W2054339472","https://openalex.org/W2062084226","https://openalex.org/W2067465054","https://openalex.org/W2075733559","https://openalex.org/W2087670482","https://openalex.org/W2089279843","https://openalex.org/W2091131538","https://openalex.org/W2099328865","https://openalex.org/W2102587794","https://openalex.org/W2105028526","https://openalex.org/W2106837218","https://openalex.org/W2106869339","https://openalex.org/W2107255080","https://openalex.org/W2107880424","https://openalex.org/W2108432765","https://openalex.org/W2112025328","https://openalex.org/W2113635885","https://openalex.org/W2122100237","https://openalex.org/W2132807638","https://openalex.org/W2135387097","https://openalex.org/W2153216542","https://openalex.org/W2161200908","https://openalex.org/W2288834458","https://openalex.org/W2331269392","https://openalex.org/W2410866476","https://openalex.org/W2797295276"],"related_works":["https://openalex.org/W2015220984","https://openalex.org/W2106869339","https://openalex.org/W2402628572","https://openalex.org/W4404716645","https://openalex.org/W2372908695","https://openalex.org/W2129542104","https://openalex.org/W2069303308","https://openalex.org/W2113635885","https://openalex.org/W2105028526","https://openalex.org/W2979124885"],"abstract_inverted_index":{"PURPOSE:":[0],"Epidemiologic":[1],"studies":[2],"suggest":[3],"that":[4,270],"prolactin":[5,27,243,271],"is":[6,273],"associated":[7,30,134],"with":[8,31,107,135,212,266],"breast":[9,32,67,138,276],"cancer":[10,33,68,139,277],"risk":[11,34,140,142,207],"in":[12,21,264,275],"older":[13],"women.":[14],"Because":[15],"of":[16,55,66,96,100,237,286],"limited":[17],"prospective":[18],"data,":[19,263],"particularly":[20,279],"younger":[22],"women,":[23],"we":[24],"examined":[25],"whether":[26],"concentrations":[28],"were":[29,79,105],"among":[35],"women":[36,211,252],"42":[37],"to":[38,127,153,187,221,248,256],"55":[39],"years":[40],"(68%":[41],"premenopausal)":[42],"from":[43,113,246,254],"the":[44,114,176,179,232,235,238,241],"Nurses'":[45],"Health":[46],"Study":[47],"(NHS),":[48],"and":[49,73,90,94,98,116,194,253],"then":[50],"conducted":[51],"a":[52,283],"pooled":[53,106,177],"analysis":[54,62],"three":[56],"studies.":[57],"PATIENTS":[58],"AND":[59],"METHODS:":[60],"The":[61,206],"included":[63],"377":[64],"cases":[65],"diagnosed":[69],"after":[70],"blood":[71,88,101],"draw":[72,89],"before":[74],"June":[75],"2000;":[76],"two":[77,108],"controls":[78],"matched":[80],"per":[81],"case":[82],"on":[83],"age,":[84],"menopausal":[85,166,199],"status":[86,200],"at":[87],"diagnosis,":[91],"fasting":[92],"status,":[93,167],"time":[95],"day":[97],"month":[99],"collection.":[102],"These":[103,262],"data":[104,111],"previously":[109],"published":[110],"sets":[112],"NHS":[115],"NHSII":[117],"cohorts":[118],"(n":[119],"=":[120,148,158,192,204,216],"1,539":[121],"cases,":[122],"2,681":[123],"controls;":[124],"ages":[125],"32":[126],"70":[128],"years).":[129],"RESULTS:":[130],"Prolactin":[131],"was":[132,182,208],"modestly":[133],"an":[136],"increased":[137,245],"(relative":[141],"[RR],":[143],"top":[144,239],"v":[145],"bottom":[146,242],"quartile":[147,244],"1.3;":[149],"95%":[150,218],"CI,":[151,185,219],"0.9":[152],"1.9;":[154],"P":[155,189,223],"for":[156,190,202,210,224,229,250,258],"trend":[157,191,225],".12).":[159],"Risk":[160],"estimates":[161],"did":[162,195],"not":[163,196],"vary":[164,197],"by":[165,198],"tumor":[168],"invasiveness,":[169],"or":[170],"estrogen":[171],"receptor":[172],"(ER)":[173],"status.":[174],"In":[175],"analysis,":[178],"overall":[180],"RR":[181,233],"1.3":[183,247],"(95%":[184],"1.1":[186],"1.6;":[188,217],".002),":[193],"(P":[201],"interaction":[203],".95).":[205],"strongest":[209],"ER+":[213,259,280],"tumors":[214],"(RR":[215],"1.2":[220],"2.0;":[222],"<":[226],".001).":[227],"Correcting":[228],"within-person":[230],"variability,":[231],"comparing":[234],"median":[236],"versus":[240],"1.7":[249],"all":[251],"1.5":[255],"2.1":[257],"cases.":[260],"CONCLUSION:":[261],"conjunction":[265],"experimental":[267],"studies,":[268],"indicate":[269],"likely":[272],"important":[274],"etiology,":[278],"tumors,":[281],"over":[282],"wide":[284],"range":[285],"ages.":[287]},"counts_by_year":[{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":11},{"year":2017,"cited_by_count":10},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":11},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":20},{"year":2012,"cited_by_count":15}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}