{"id":"https://openalex.org/W2098488170","doi":"https://doi.org/10.1016/j.bbmt.2013.04.006","title":"Graft-versus-Host-Disease after Double Cord Blood Transplantation: A New Look at Its Characteristics","display_name":"Graft-versus-Host-Disease after Double Cord Blood Transplantation: A New Look at Its Characteristics","publication_year":2013,"publication_date":"2013-04-10","ids":{"openalex":"https://openalex.org/W2098488170","doi":"https://doi.org/10.1016/j.bbmt.2013.04.006","mag":"2098488170","pmid":"https://pubmed.ncbi.nlm.nih.gov/23583824"},"language":"en","primary_location":{"id":"doi:10.1016/j.bbmt.2013.04.006","doi":"https://doi.org/10.1016/j.bbmt.2013.04.006","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbmt.2013.04.006","pdf_url":"http://www.astctjournal.org/article/S1083879113001511/pdf","source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Blood and Marrow Transplantation","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"http://www.astctjournal.org/article/S1083879113001511/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055685996","display_name":"Filippo Milano","orcid":"https://orcid.org/0000-0003-3573-2159","observed_orcids":["https://orcid.org/0000-0003-3573-2159"]},"institutions":[{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Filippo Milano","raw_affiliation_strings":["Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98103, USA. fmilano@fhcrc.org","Clinical Research Division, Fred Hutchinson Cancer research Center, Seattle, Washington"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98103, USA. fmilano@fhcrc.org","institution_ids":["https://openalex.org/I4210089486"]},{"raw_affiliation_string":"Clinical Research Division, Fred Hutchinson Cancer research Center, Seattle, Washington","institution_ids":["https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025632410","display_name":"Colleen S. Delaney","orcid":"https://orcid.org/0000-0002-1044-2801","observed_orcids":["https://orcid.org/0000-0002-1044-2801"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Colleen Delaney","raw_affiliation_strings":["Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington","Department of Pediatrics, University of Washington, Seattle, Washington"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington","institution_ids":["https://openalex.org/I4210089486"]},{"raw_affiliation_string":"Department of Pediatrics, University of Washington, Seattle, Washington","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085787488","display_name":"Rainer F Storb","orcid":"https://orcid.org/0000-0002-9343-4099","observed_orcids":["https://orcid.org/0000-0002-9343-4099"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rainer Storb","raw_affiliation_strings":["Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington","Department of Medicine, University of Washington, Seattle, Washington"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington","institution_ids":["https://openalex.org/I4210089486"]},{"raw_affiliation_string":"Department of Medicine, University of Washington, Seattle, Washington","institution_ids":["https://openalex.org/I201448701"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5055685996"],"corresponding_institution_ids":["https://openalex.org/I4210089486"],"apc_list":{"value":3650,"currency":"USD","value_usd":3650},"apc_paid":{"value":3650,"currency":"USD","value_usd":3650},"fwci":0.4779,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.70805328,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"19","issue":"6","first_page":"847","last_page":"848"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12900","display_name":"Organ and Tissue Transplantation Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/graft-versus-host-disease","display_name":"graft-versus-host disease","score":0.9980000257492065},{"id":"https://openalex.org/keywords/double-cord-blood-transplantation","display_name":"double cord blood transplantation","score":0.8450000286102295},{"id":"https://openalex.org/keywords/cord-blood-transplantation","display_name":"cord blood transplantation","score":0.9810000061988831},{"id":"https://openalex.org/keywords/acute-graft-versus-host-disease","display_name":"acute graft-versus-host disease","score":0.9660000205039978},{"id":"https://openalex.org/keywords/chronic-graft-versus-host-disease","display_name":"chronic graft-versus-host disease","score":0.996999979019165},{"id":"https://openalex.org/keywords/hematopoietic-stem-cell-transplantation","display_name":"hematopoietic stem cell transplantation","score":0.8809999823570251},{"id":"https://openalex.org/keywords/cord-blood-donors","display_name":"cord blood donors","score":0.37299999594688416}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8959347009658813},{"id":"https://openalex.org/C2776955114","wikidata":"https://www.wikidata.org/wiki/Q172563","display_name":"Umbilical cord","level":2,"score":0.7429254651069641},{"id":"https://openalex.org/C2908824208","wikidata":"https://www.wikidata.org/wiki/Q914952","display_name":"Umbilical Cord Blood Transplantation","level":4,"score":0.6945531964302063},{"id":"https://openalex.org/C2780914630","wikidata":"https://www.wikidata.org/wiki/Q914952","display_name":"Cord blood","level":2,"score":0.6218315958976746},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.6095411777496338},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.5571202039718628},{"id":"https://openalex.org/C2777408962","wikidata":"https://www.wikidata.org/wiki/Q1128050","display_name":"Hematopoietic stem cell transplantation","level":3,"score":0.5433955192565918},{"id":"https://openalex.org/C2779972918","wikidata":"https://www.wikidata.org/wiki/Q1194520","display_name":"Graft-versus-host disease","level":3,"score":0.5128705501556396},{"id":"https://openalex.org/C109159458","wikidata":"https://www.wikidata.org/wiki/Q919283","display_name":"Haematopoiesis","level":3,"score":0.48264819383621216},{"id":"https://openalex.org/C2778461978","wikidata":"https://www.wikidata.org/wiki/Q29496","display_name":"Leukemia","level":2,"score":0.468546986579895},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4559933841228485},{"id":"https://openalex.org/C83867959","wikidata":"https://www.wikidata.org/wiki/Q371467","display_name":"Scopus","level":3,"score":0.4165585935115814},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.40503570437431335},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3733125329017639},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3489254415035248},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.07426467537879944},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.047054678201675415},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006086","descriptor_name":"Graft vs Host Disease","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D006680","descriptor_name":"HLA Antigens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019172","descriptor_name":"Transplantation Conditioning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019337","descriptor_name":"Hematologic Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D019653","descriptor_name":"Myeloablative Agonists","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D036101","descriptor_name":"Cord Blood Stem Cell Transplantation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D041981","descriptor_name":"Gastrointestinal Tract","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.bbmt.2013.04.006","doi":"https://doi.org/10.1016/j.bbmt.2013.04.006","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbmt.2013.04.006","pdf_url":"http://www.astctjournal.org/article/S1083879113001511/pdf","source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Blood and Marrow Transplantation","raw_type":"journal-article"},{"id":"pmid:23583824","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23583824","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.bbmt.2013.04.006","doi":"https://doi.org/10.1016/j.bbmt.2013.04.006","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbmt.2013.04.006","pdf_url":"http://www.astctjournal.org/article/S1083879113001511/pdf","source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Blood and Marrow Transplantation","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2098488170.pdf"},"referenced_works_count":20,"referenced_works":["https://openalex.org/W1965613868","https://openalex.org/W1968205826","https://openalex.org/W1973881356","https://openalex.org/W2014503294","https://openalex.org/W2018953748","https://openalex.org/W2028795322","https://openalex.org/W2034253271","https://openalex.org/W2039964265","https://openalex.org/W2045254759","https://openalex.org/W2091975228","https://openalex.org/W2106428824","https://openalex.org/W2111717354","https://openalex.org/W2135067231","https://openalex.org/W2141557403","https://openalex.org/W2317259161","https://openalex.org/W2330713242","https://openalex.org/W2333162405","https://openalex.org/W2379365975","https://openalex.org/W2618073389","https://openalex.org/W3150257811"],"related_works":["https://openalex.org/W2910585512","https://openalex.org/W2039964265","https://openalex.org/W2041720137","https://openalex.org/W2065770071","https://openalex.org/W2590912865","https://openalex.org/W2143465292","https://openalex.org/W2593027648","https://openalex.org/W921425538","https://openalex.org/W2551247308","https://openalex.org/W2988406024"],"abstract_inverted_index":{"Umbilical":[0],"cord":[1],"blood":[2,63],"transplantation":[3,69],"(UCBT)":[4],"has":[5],"become":[6],"a":[7],"widely":[8],"available":[9],"and":[10,18,23,49],"accepted":[11],"alternative":[12],"stem":[13],"cell":[14,68],"source":[15],"for":[16],"pediatric":[17],"adult":[19],"patients":[20],"with":[21,57],"malignant":[22],"nonmalignant":[24],"hematologic":[25],"diseases":[26],"[1-4].":[27],"Over":[28],"the":[29],"last":[30],"several":[31],"years,":[32],"multiple":[33],"studies":[34],"have":[35],"reported":[36],"lower":[37],"rates":[38],"of":[39,59],"graft-versus-host":[40],"disease":[41],"(GVHD),":[42],"both":[43],"grade":[44],"III-IV":[45],"acute":[46],"GVHD":[47,51],"(aGVHD)":[48],"chronic":[50],"(cGVHD),":[52],"in":[53],"UCBT":[54],"recipients":[55,58],"compared":[56],"unrelated":[60],"donor":[61],"peripheral":[62],"or":[64],"bone":[65],"marrow":[66],"hematopoietic":[67],"(HCT)":[70],"[5-7].":[71]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}