{"id":"https://openalex.org/W2098448352","doi":"https://doi.org/10.1080/10635150600755453","title":"Approximate Likelihood-Ratio Test for Branches: A Fast, Accurate, and Powerful Alternative","display_name":"Approximate Likelihood-Ratio Test for Branches: A Fast, Accurate, and Powerful Alternative","publication_year":2006,"publication_date":"2006-06-19","ids":{"openalex":"https://openalex.org/W2098448352","doi":"https://doi.org/10.1080/10635150600755453","mag":"2098448352","pmid":"https://pubmed.ncbi.nlm.nih.gov/16785212"},"language":"en","primary_location":{"id":"doi:10.1080/10635150600755453","doi":"https://doi.org/10.1080/10635150600755453","is_oa":true,"landing_page_url":"https://doi.org/10.1080/10635150600755453","pdf_url":"https://academic.oup.com/sysbio/article-pdf/55/4/539/24200256/55-4-539.pdf","source":{"id":"https://openalex.org/S65478581","display_name":"Systematic Biology","issn_l":"1063-5157","issn":["1063-5157","1076-836X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-1","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Systematic Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/sysbio/article-pdf/55/4/539/24200256/55-4-539.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046692009","display_name":"Maria O. Anisimova","orcid":"https://orcid.org/0000-0001-8145-7966","observed_orcids":["https://orcid.org/0000-0001-8145-7966","https://orcid.org/0000-0001-6508-0249"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210101743","display_name":"Laboratoire d'Informatique, de Robotique et de Micro\u00e9lectronique de Montpellier","ror":"https://ror.org/013yean28","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1326498283","https://openalex.org/I151295451","https://openalex.org/I19894307","https://openalex.org/I4210101743","https://openalex.org/I4210159245","https://openalex.org/I4405261681"]},{"id":"https://openalex.org/I4387154756","display_name":"Universit\u00e9 Montpellier 2","ror":"https://ror.org/00wh4bp03","country_code":"FR","type":"education","lineage":["https://openalex.org/I19894307","https://openalex.org/I4387154756"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Maria Anisimova","raw_affiliation_strings":["Equipe M\u00e9thodes et Algorithmes pour la Bioinformatique LIRMM-CNRS, Universit\u00e9 Montpellier II Montpellier, 34392, France E-mail: manisimova@hotmail.com (M.A.); gascuel@lirmm.fr (O.G.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Equipe M\u00e9thodes et Algorithmes pour la Bioinformatique LIRMM-CNRS, Universit\u00e9 Montpellier II Montpellier, 34392, France E-mail: manisimova@hotmail.com (M.A.); gascuel@lirmm.fr (O.G.)","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210101743","https://openalex.org/I4387154756"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078068308","display_name":"Olivier Gascuel","orcid":"https://orcid.org/0000-0002-9412-9723","observed_orcids":["https://orcid.org/0000-0002-9412-9723"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210101743","display_name":"Laboratoire d'Informatique, de Robotique et de Micro\u00e9lectronique de Montpellier","ror":"https://ror.org/013yean28","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1326498283","https://openalex.org/I151295451","https://openalex.org/I19894307","https://openalex.org/I4210101743","https://openalex.org/I4210159245","https://openalex.org/I4405261681"]},{"id":"https://openalex.org/I4387154756","display_name":"Universit\u00e9 Montpellier 2","ror":"https://ror.org/00wh4bp03","country_code":"FR","type":"education","lineage":["https://openalex.org/I19894307","https://openalex.org/I4387154756"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Olivier Gascuel","raw_affiliation_strings":["Equipe M\u00e9thodes et Algorithmes pour la Bioinformatique LIRMM-CNRS, Universit\u00e9 Montpellier II Montpellier, 34392, France E-mail: manisimova@hotmail.com (M.A.); gascuel@lirmm.fr (O.G.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Equipe M\u00e9thodes et Algorithmes pour la Bioinformatique LIRMM-CNRS, Universit\u00e9 Montpellier II Montpellier, 34392, France E-mail: manisimova@hotmail.com (M.A.); gascuel@lirmm.fr (O.G.)","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210101743","https://openalex.org/I4387154756"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5046692009","https://openalex.org/A5078068308"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210101743","https://openalex.org/I4387154756"],"apc_list":{"value":2166,"currency":"USD","value_usd":2166},"apc_paid":null,"fwci":15.6072,"has_fulltext":true,"cited_by_count":2730,"citation_normalized_percentile":{"value":0.99720363,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"55","issue":"4","first_page":"539","last_page":"552"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11354","display_name":"Evolution and Paleontology Studies","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1911","display_name":"Paleontology"},"field":{"id":"https://openalex.org/fields/19","display_name":"Earth and Planetary Sciences"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/branch-support","display_name":"branch support","score":0.902999997138977},{"id":"https://openalex.org/keywords/phylogenetic-tree","display_name":"phylogenetic tree","score":0.8840000033378601},{"id":"https://openalex.org/keywords/maximum-likelihood-estimation","display_name":"maximum likelihood estimation","score":0.4779999852180481},{"id":"https://openalex.org/keywords/bootstrap-method","display_name":"bootstrapping","score":0.32600000500679016},{"id":"https://openalex.org/keywords/bayesian-posterior-probability","display_name":"Bayesian posterior probability","score":0.6779999732971191},{"id":"https://openalex.org/keywords/asymptotic-distribution","display_name":"asymptotic distribution","score":0.6190000176429749},{"id":"https://openalex.org/keywords/chi-square-distribution","display_name":"chi-square distribution","score":0.5849999785423279},{"id":"https://openalex.org/keywords/phyml","display_name":"PhyML","score":0.597000002861023},{"id":"https://openalex.org/keywords/molecular-phylogeny","display_name":"molecular phylogeny","score":0.5099999904632568},{"id":"https://openalex.org/keywords/statistical-significance-testing","display_name":"statistical significance testing","score":0.4950000047683716}],"concepts":[{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.737362265586853},{"id":"https://openalex.org/C9483764","wikidata":"https://www.wikidata.org/wiki/Q585740","display_name":"Likelihood-ratio test","level":2,"score":0.6559457778930664},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.5904478430747986},{"id":"https://openalex.org/C113174947","wikidata":"https://www.wikidata.org/wiki/Q2859736","display_name":"Tree (set theory)","level":2,"score":0.5407183170318604},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.5073718428611755},{"id":"https://openalex.org/C169857963","wikidata":"https://www.wikidata.org/wiki/Q1461038","display_name":"Test statistic","level":3,"score":0.4780200719833374},{"id":"https://openalex.org/C87007009","wikidata":"https://www.wikidata.org/wiki/Q210832","display_name":"Statistical hypothesis testing","level":2,"score":0.4778668284416199},{"id":"https://openalex.org/C102366305","wikidata":"https://www.wikidata.org/wiki/Q1097688","display_name":"Nonparametric statistics","level":2,"score":0.4373984634876251},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.27988117933273315}],"mesh":[{"descriptor_ui":"D002965","descriptor_name":"Classification","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016013","descriptor_name":"Likelihood Functions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1080/10635150600755453","doi":"https://doi.org/10.1080/10635150600755453","is_oa":true,"landing_page_url":"https://doi.org/10.1080/10635150600755453","pdf_url":"https://academic.oup.com/sysbio/article-pdf/55/4/539/24200256/55-4-539.pdf","source":{"id":"https://openalex.org/S65478581","display_name":"Systematic Biology","issn_l":"1063-5157","issn":["1063-5157","1076-836X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-1","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Systematic Biology","raw_type":"journal-article"},{"id":"pmid:16785212","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16785212","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Systematic biology","raw_type":"Comparative Study"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.320.346","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.320.346","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://people.inf.ethz.ch/anmaria/papers/AnisimovaGascuel_SystBiol-small.pdf","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.335.5101","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.335.5101","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www2.lirmm.fr/mab/IMG/pdf/AnisimovaGascuel_SystBiol.pdf","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.470.6200","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.470.6200","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://hal-lirmm.ccsd.cnrs.fr/docs/00/13/66/58/PDF/AnisimovaGascuel_SystBiol.pdf","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.538.9784","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.538.9784","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://sysbio.oxfordjournals.org/content/55/4/539.full.pdf","raw_type":"text"},{"id":"pmh:oai:HAL:lirmm-00136658v1","doi":null,"is_oa":true,"landing_page_url":"https://hal-lirmm.ccsd.cnrs.fr/lirmm-00136658","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Systematic Biology, 2006, 55 (4), pp.539-552. ⟨10.1080/10635150600755453⟩","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1080/10635150600755453","doi":"https://doi.org/10.1080/10635150600755453","is_oa":true,"landing_page_url":"https://doi.org/10.1080/10635150600755453","pdf_url":"https://academic.oup.com/sysbio/article-pdf/55/4/539/24200256/55-4-539.pdf","source":{"id":"https://openalex.org/S65478581","display_name":"Systematic Biology","issn_l":"1063-5157","issn":["1063-5157","1076-836X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-1","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Systematic Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2098448352.pdf","grobid_xml":"https://content.openalex.org/works/W2098448352.grobid-xml"},"referenced_works_count":60,"referenced_works":["https://openalex.org/W186942286","https://openalex.org/W791550880","https://openalex.org/W823964433","https://openalex.org/W1966972227","https://openalex.org/W1977606907","https://openalex.org/W1981509964","https://openalex.org/W1982447955","https://openalex.org/W1983002447","https://openalex.org/W1985175395","https://openalex.org/W1990611835","https://openalex.org/W1995945562","https://openalex.org/W2009570821","https://openalex.org/W2010814032","https://openalex.org/W2019032222","https://openalex.org/W2021415417","https://openalex.org/W2022261649","https://openalex.org/W2029423003","https://openalex.org/W2030966943","https://openalex.org/W2031211350","https://openalex.org/W2045951268","https://openalex.org/W2046076301","https://openalex.org/W2048971218","https://openalex.org/W2051992638","https://openalex.org/W2057293816","https://openalex.org/W2057303183","https://openalex.org/W2064028310","https://openalex.org/W2068225247","https://openalex.org/W2082928585","https://openalex.org/W2102736136","https://openalex.org/W2102862543","https://openalex.org/W2103546861","https://openalex.org/W2106750393","https://openalex.org/W2109225629","https://openalex.org/W2120927723","https://openalex.org/W2125359798","https://openalex.org/W2126843316","https://openalex.org/W2126999711","https://openalex.org/W2133724975","https://openalex.org/W2141913814","https://openalex.org/W2147021949","https://openalex.org/W2148530335","https://openalex.org/W2150098563","https://openalex.org/W2150783480","https://openalex.org/W2151527745","https://openalex.org/W2152886327","https://openalex.org/W2154723180","https://openalex.org/W2159098268","https://openalex.org/W2160364329","https://openalex.org/W2161444534","https://openalex.org/W2161647617","https://openalex.org/W2162421185","https://openalex.org/W2325940284","https://openalex.org/W2331304652","https://openalex.org/W3009906763","https://openalex.org/W3022255685","https://openalex.org/W3106889297","https://openalex.org/W4206702770","https://openalex.org/W4233815609","https://openalex.org/W4245668478","https://openalex.org/W4297568210"],"related_works":["https://openalex.org/W7099485902","https://openalex.org/W2139146574","https://openalex.org/W7095940945","https://openalex.org/W2067806453","https://openalex.org/W2069359429","https://openalex.org/W2111211467","https://openalex.org/W1985175395","https://openalex.org/W2185521588","https://openalex.org/W7145890809","https://openalex.org/W2962157070"],"abstract_inverted_index":{"We":[0,64],"revisit":[1],"statistical":[2],"tests":[3],"for":[4,20,96],"branches":[5,21],"of":[6,35,45,76,90,138,158,182,198,214],"evolutionary":[7],"trees":[8],"reconstructed":[9],"upon":[10],"molecular":[11],"data.":[12],"A":[13],"new,":[14],"fast,":[15],"approximate":[16],"likelihood-ratio":[17],"test":[18,101,142,185],"(aLRT)":[19],"is":[22,40,70,103,143,150,203,219],"presented":[23],"here":[24],"as":[25,73,112],"a":[26,74,106,141],"competitive":[27],"alternative":[28],"to":[29,54,125,175,205,211],"nonparametric":[30],"bootstrap":[31],"and":[32,129,160,192,209,236],"Bayesian":[33],"estimation":[34,232],"branch":[36,60,92,137,157],"support.":[37],"The":[38,87,180,201,217],"aLRT":[39,89,202,218],"based":[41],"on":[42,188],"the":[43,46,50,55,58,67,82,100,117,120,126,130,136,146,156,161,176,183,222,226],"idea":[44],"conventional":[47],"LRT,":[48],"with":[49,196],"null":[51],"hypothesis":[52],"corresponding":[53,124,174],"assumption":[56],"that":[57,66],"inferred":[59],"has":[61],"length":[62],"0.":[63],"show":[65],"LRT":[68],"statistic":[69,102],"asymptotically":[71],"distributed":[72],"maximum":[75,121,229],"three":[77],"random":[78],"variables":[79],"drawn":[80],"from":[81],"chi(0)2":[83],"+":[84],"chi(1)2":[85],"distribution.":[86],"new":[88,184],"interior":[91],"uses":[93],"this":[94],"distribution":[95],"significance":[97],"testing,":[98],"but":[99,109],"approximated":[104],"in":[105],"slightly":[107],"conservative":[108],"practical":[110],"way":[111],"2(l1-":[113],"l2),":[114],"i.e.,":[115],"double":[116],"difference":[118],"between":[119],"log-likelihood":[122,147],"values":[123,173],"best":[127,132,177],"tree":[128,231],"second":[131],"topological":[133],"arrangement":[134],"around":[135],"interest.":[139],"Such":[140],"fast":[144,228],"because":[145],"value":[148],"l2":[149],"computed":[151],"by":[152,225],"optimizing":[153],"only":[154],"over":[155],"interest":[159],"four":[162],"adjacent":[163],"branches,":[164],"whereas":[165],"other":[166],"parameters":[167],"are":[168],"fixed":[169],"at":[170],"their":[171],"optimal":[172],"ML":[178],"tree.":[179],"performance":[181],"was":[186],"studied":[187],"simulated":[189],"4-,":[190],"12-,":[191],"100-taxon":[193],"data":[194],"sets":[195],"sequences":[197],"different":[199],"lengths.":[200],"shown":[204],"be":[206],"accurate,":[207],"powerful,":[208],"robust":[210],"certain":[212],"violations":[213],"model":[215],"assumptions.":[216],"implemented":[220],"within":[221],"algorithm":[223],"used":[224],"recent":[227],"likelihood":[230],"program":[233],"PHYML":[234],"(Guindon":[235],"Gascuel,":[237],"2003).":[238]},"counts_by_year":[{"year":2026,"cited_by_count":71},{"year":2025,"cited_by_count":98},{"year":2024,"cited_by_count":129},{"year":2023,"cited_by_count":135},{"year":2022,"cited_by_count":153},{"year":2021,"cited_by_count":176},{"year":2020,"cited_by_count":178},{"year":2019,"cited_by_count":151},{"year":2018,"cited_by_count":163},{"year":2017,"cited_by_count":159},{"year":2016,"cited_by_count":149},{"year":2015,"cited_by_count":179},{"year":2014,"cited_by_count":210},{"year":2013,"cited_by_count":181},{"year":2012,"cited_by_count":175}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}