{"id":"https://openalex.org/W2098345480","doi":"https://doi.org/10.1002/adhm.201400687","title":"Coupling Freshly Isolated CD44 + Infrapatellar Fat Pad\u2010Derived Stromal Cells with a TGF\u2010\u03b23 Eluting Cartilage ECM\u2010Derived Scaffold as a Single\u2010Stage Strategy for Promoting Chondrogenesis","display_name":"Coupling Freshly Isolated CD44 + Infrapatellar Fat Pad\u2010Derived Stromal Cells with a TGF\u2010\u03b23 Eluting Cartilage ECM\u2010Derived Scaffold as a Single\u2010Stage Strategy for Promoting Chondrogenesis","publication_year":2015,"publication_date":"2015-02-06","ids":{"openalex":"https://openalex.org/W2098345480","doi":"https://doi.org/10.1002/adhm.201400687","mag":"2098345480","pmid":"https://pubmed.ncbi.nlm.nih.gov/25656563"},"language":"en","primary_location":{"id":"doi:10.1002/adhm.201400687","doi":"https://doi.org/10.1002/adhm.201400687","is_oa":false,"landing_page_url":"https://doi.org/10.1002/adhm.201400687","pdf_url":null,"source":{"id":"https://openalex.org/S2500736452","display_name":"Advanced Healthcare Materials","issn_l":"2192-2640","issn":["2192-2640","2192-2659"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced Healthcare Materials","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/2262/82240","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036901558","display_name":"Henrique Vaz\u00e3o de Almeida","orcid":"https://orcid.org/0000-0001-9123-4475","observed_orcids":["https://orcid.org/0000-0001-9123-4475"]},"institutions":[{"id":"https://openalex.org/I205274468","display_name":"Trinity College Dublin","ror":"https://ror.org/02tyrky19","country_code":"IE","type":"education","lineage":["https://openalex.org/I205274468"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Henrique V. Almeida","raw_affiliation_strings":["Department of Mechanical and Manufacturing Engineering, School of Engineering, Trinity College Dublin, Dublin 2, Ireland","Trinity Centre for Bioengineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mechanical and Manufacturing Engineering, School of Engineering, Trinity College Dublin, Dublin 2, Ireland","institution_ids":["https://openalex.org/I205274468"]},{"raw_affiliation_string":"Trinity Centre for Bioengineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland","institution_ids":["https://openalex.org/I205274468"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082792190","display_name":"Gr\u00e1inne M. Cunniffe","orcid":"https://orcid.org/0000-0001-7085-1706","observed_orcids":["https://orcid.org/0000-0001-7085-1706"]},"institutions":[{"id":"https://openalex.org/I205274468","display_name":"Trinity College Dublin","ror":"https://ror.org/02tyrky19","country_code":"IE","type":"education","lineage":["https://openalex.org/I205274468"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Gr\u00e1inne M. Cunniffe","raw_affiliation_strings":["Department of Mechanical and Manufacturing Engineering, School of Engineering, Trinity College Dublin, Dublin 2, Ireland","Trinity Centre for Bioengineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mechanical and Manufacturing Engineering, School of Engineering, Trinity College Dublin, Dublin 2, Ireland","institution_ids":["https://openalex.org/I205274468"]},{"raw_affiliation_string":"Trinity Centre for Bioengineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland","institution_ids":["https://openalex.org/I205274468"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023142004","display_name":"Tatiana Vinardell","orcid":"https://orcid.org/0000-0002-4902-6725","observed_orcids":["https://orcid.org/0000-0002-4902-6725"]},"institutions":[{"id":"https://openalex.org/I100930933","display_name":"University College Dublin","ror":"https://ror.org/05m7pjf47","country_code":"IE","type":"education","lineage":["https://openalex.org/I100930933"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Tatiana Vinardell","raw_affiliation_strings":["School of Agriculture and Food Science, University College Dublin, Belfield, Dublin 4, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Agriculture and Food Science, University College Dublin, Belfield, Dublin 4, Ireland","institution_ids":["https://openalex.org/I100930933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081947117","display_name":"Conor Timothy Buckley","orcid":"https://orcid.org/0000-0001-7452-4534","observed_orcids":["https://orcid.org/0000-0001-7452-4534"]},"institutions":[{"id":"https://openalex.org/I205274468","display_name":"Trinity College Dublin","ror":"https://ror.org/02tyrky19","country_code":"IE","type":"education","lineage":["https://openalex.org/I205274468"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Conor T. Buckley","raw_affiliation_strings":["Department of Mechanical and Manufacturing Engineering, School of Engineering, Trinity College Dublin, Dublin 2, Ireland","Trinity Centre for Bioengineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mechanical and Manufacturing Engineering, School of Engineering, Trinity College Dublin, Dublin 2, Ireland","institution_ids":["https://openalex.org/I205274468"]},{"raw_affiliation_string":"Trinity Centre for Bioengineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland","institution_ids":["https://openalex.org/I205274468"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066974810","display_name":"Fergal J. O\u2019Brien","orcid":"https://orcid.org/0000-0003-2030-8005","observed_orcids":["https://orcid.org/0000-0003-2030-8005"]},"institutions":[{"id":"https://openalex.org/I142762351","display_name":"Royal College of Surgeons in Ireland","ror":"https://ror.org/01hxy9878","country_code":"IE","type":"education","lineage":["https://openalex.org/I142762351"]},{"id":"https://openalex.org/I205274468","display_name":"Trinity College Dublin","ror":"https://ror.org/02tyrky19","country_code":"IE","type":"education","lineage":["https://openalex.org/I205274468"]},{"id":"https://openalex.org/I4210112033","display_name":"Advanced Materials and BioEngineering Research","ror":"https://ror.org/01c4rxk68","country_code":"IE","type":"facility","lineage":["https://openalex.org/I142762351","https://openalex.org/I188760350","https://openalex.org/I205274468","https://openalex.org/I230495080","https://openalex.org/I27577105","https://openalex.org/I4210112033","https://openalex.org/I42934936"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Fergal J. O'Brien","raw_affiliation_strings":["Advanced Materials and Bioengineering Research Centre (AMBER), Trinity College Dublin and RCSI, Dublin 2, Ireland","Department of Anatomy, Royal College of Surgeons in Ireland, Dublin 2, Ireland","Trinity Centre for Bioengineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Advanced Materials and Bioengineering Research Centre (AMBER), Trinity College Dublin and RCSI, Dublin 2, Ireland","institution_ids":["https://openalex.org/I205274468","https://openalex.org/I4210112033"]},{"raw_affiliation_string":"Department of Anatomy, Royal College of Surgeons in Ireland, Dublin 2, Ireland","institution_ids":["https://openalex.org/I142762351"]},{"raw_affiliation_string":"Trinity Centre for Bioengineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland","institution_ids":["https://openalex.org/I205274468"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045482826","display_name":"Daniel John Kelly","orcid":"https://orcid.org/0000-0003-4091-0992","observed_orcids":["https://orcid.org/0000-0003-4091-0992"]},"institutions":[{"id":"https://openalex.org/I142762351","display_name":"Royal College of Surgeons in Ireland","ror":"https://ror.org/01hxy9878","country_code":"IE","type":"education","lineage":["https://openalex.org/I142762351"]},{"id":"https://openalex.org/I205274468","display_name":"Trinity College Dublin","ror":"https://ror.org/02tyrky19","country_code":"IE","type":"education","lineage":["https://openalex.org/I205274468"]},{"id":"https://openalex.org/I4210112033","display_name":"Advanced Materials and BioEngineering Research","ror":"https://ror.org/01c4rxk68","country_code":"IE","type":"facility","lineage":["https://openalex.org/I142762351","https://openalex.org/I188760350","https://openalex.org/I205274468","https://openalex.org/I230495080","https://openalex.org/I27577105","https://openalex.org/I4210112033","https://openalex.org/I42934936"]}],"countries":["IE"],"is_corresponding":true,"raw_author_name":"Daniel J. Kelly","raw_affiliation_strings":["Advanced Materials and Bioengineering Research Centre (AMBER), Trinity College Dublin and RCSI, Dublin 2, Ireland","Department of Anatomy, Royal College of Surgeons in Ireland, Dublin 2, Ireland","Department of Mechanical and Manufacturing Engineering, School of Engineering, Trinity College Dublin, Dublin 2, Ireland","Trinity Centre for Bioengineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Advanced Materials and Bioengineering Research Centre (AMBER), Trinity College Dublin and RCSI, Dublin 2, Ireland","institution_ids":["https://openalex.org/I205274468","https://openalex.org/I4210112033"]},{"raw_affiliation_string":"Department of Anatomy, Royal College of Surgeons in Ireland, Dublin 2, Ireland","institution_ids":["https://openalex.org/I142762351"]},{"raw_affiliation_string":"Department of Mechanical and Manufacturing Engineering, School of Engineering, Trinity College Dublin, Dublin 2, Ireland","institution_ids":["https://openalex.org/I205274468"]},{"raw_affiliation_string":"Trinity Centre for Bioengineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland","institution_ids":["https://openalex.org/I205274468"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5045482826"],"corresponding_institution_ids":["https://openalex.org/I142762351","https://openalex.org/I205274468","https://openalex.org/I4210112033"],"apc_list":{"value":4880,"currency":"USD","value_usd":4880},"apc_paid":null,"fwci":8.0811,"has_fulltext":true,"cited_by_count":81,"citation_normalized_percentile":{"value":0.98087804,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"4","issue":"7","first_page":"1043","last_page":"1053"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.4611999988555908,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.4611999988555908,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.42579999566078186,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.04690000042319298,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cd44-cells","display_name":"CD44+ cells","score":0.8820000290870667},{"id":"https://openalex.org/keywords/freeze-drying","display_name":"freeze-drying","score":0.5419999957084656},{"id":"https://openalex.org/keywords/cryomilling","display_name":"cryomilling","score":0.746999979019165},{"id":"https://openalex.org/keywords/chondrogenic-differentiation","display_name":"chondrogenic differentiation","score":0.8840000033378601},{"id":"https://openalex.org/keywords/sulfated-glycosaminoglycans","display_name":"sulfated glycosaminoglycans","score":0.9079999923706055},{"id":"https://openalex.org/keywords/type-ii-collagen","display_name":"type II collagen","score":0.7730000019073486},{"id":"https://openalex.org/keywords/scaffold-porosity","display_name":"scaffold porosity","score":0.9100000262260437},{"id":"https://openalex.org/keywords/joint-regeneration","display_name":"joint regeneration","score":0.8320000171661377},{"id":"https://openalex.org/keywords/cartilage-tissue-engineering","display_name":"cartilage tissue engineering","score":0.6510000228881836}],"concepts":[{"id":"https://openalex.org/C35496256","wikidata":"https://www.wikidata.org/wiki/Q5104524","display_name":"Chondrogenesis","level":3,"score":0.9087272882461548},{"id":"https://openalex.org/C2776610510","wikidata":"https://www.wikidata.org/wiki/Q2624131","display_name":"Infrapatellar fat pad","level":4,"score":0.7300878763198853},{"id":"https://openalex.org/C89429830","wikidata":"https://www.wikidata.org/wiki/Q735710","display_name":"Scaffold","level":2,"score":0.6338576674461365},{"id":"https://openalex.org/C16930146","wikidata":"https://www.wikidata.org/wiki/Q4381253","display_name":"Stromal cell","level":2,"score":0.6286463141441345},{"id":"https://openalex.org/C2780932548","wikidata":"https://www.wikidata.org/wiki/Q1056532","display_name":"CD44","level":3,"score":0.5854814648628235},{"id":"https://openalex.org/C2780550940","wikidata":"https://www.wikidata.org/wiki/Q502730","display_name":"Cartilage","level":2,"score":0.5701205134391785},{"id":"https://openalex.org/C131584629","wikidata":"https://www.wikidata.org/wiki/Q4308705","display_name":"Coupling (piping)","level":2,"score":0.5294979214668274},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.5209683179855347},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.4346140921115875},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4204443693161011},{"id":"https://openalex.org/C2776363554","wikidata":"https://www.wikidata.org/wiki/Q14907085","display_name":"RUNX2","level":4,"score":0.41019272804260254},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3523913323879242},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3373286724090576},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.24253660440444946},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.20395207405090332},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.1905466914176941},{"id":"https://openalex.org/C2778260815","wikidata":"https://www.wikidata.org/wiki/Q917177","display_name":"Osteoblast","level":3,"score":0.17713457345962524},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.17315611243247986},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.17061945796012878},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.16163262724876404},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.12406843900680542},{"id":"https://openalex.org/C2776164576","wikidata":"https://www.wikidata.org/wiki/Q62736","display_name":"Osteoarthritis","level":3,"score":0.10250359773635864},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09491086006164551},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000273","descriptor_name":"Adipose Tissue","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000273","descriptor_name":"Adipose Tissue","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002358","descriptor_name":"Cartilage, Articular","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002358","descriptor_name":"Cartilage, Articular","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005109","descriptor_name":"Extracellular Matrix","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005109","descriptor_name":"Extracellular Matrix","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012038","descriptor_name":"Regeneration","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017154","descriptor_name":"Stromal Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018960","descriptor_name":"Hyaluronan Receptors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020219","descriptor_name":"Chondrogenesis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D023822","descriptor_name":"Tissue Engineering","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D024043","descriptor_name":"Collagen Type II","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D044968","descriptor_name":"Regenerative Medicine","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D053782","descriptor_name":"Transforming Growth Factor beta3","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D054457","descriptor_name":"Tissue Scaffolds","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1002/adhm.201400687","doi":"https://doi.org/10.1002/adhm.201400687","is_oa":false,"landing_page_url":"https://doi.org/10.1002/adhm.201400687","pdf_url":null,"source":{"id":"https://openalex.org/S2500736452","display_name":"Advanced Healthcare Materials","issn_l":"2192-2640","issn":["2192-2640","2192-2659"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced Healthcare Materials","raw_type":"journal-article"},{"id":"pmid:25656563","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25656563","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced healthcare materials","raw_type":"Journal Article"},{"id":"pmh:http://www.rian.ie/146627/","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2262/82240","pdf_url":"http://hdl.handle.net/2262/82240","source":{"id":"https://openalex.org/S4306400033","display_name":"Arrow@dit (Dublin Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210144925","host_organization_name":"Technological University Dublin","host_organization_lineage":["https://openalex.org/I4210144925"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Almeida, A.V, Cunniffe, G.M., Vinardell, T., Buckley, C.T., O?Brien, F.J., Kelly, D.J., Coupling freshly isolated CD44+ infrapatellar fat pad derived stromal cells with a tgf-&amp;#946;3 eluting cartilage ecm-derived scaffold as a single stage strategy for promoting chondrogenesis., Advanced Healthcare Materials, 4, 7, 2015, 1043-1053","raw_type":"Journal article"},{"id":"pmh:oai:epubs.rcsi.ie:anatart-1078","doi":null,"is_oa":true,"landing_page_url":"https://epubs.rcsi.ie/cgi/viewcontent.cgi?article=1078&context=anatart","pdf_url":null,"source":null,"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Anatomy Articles","raw_type":"text"},{"id":"pmh:oai:figshare.com:article/10766417","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Coupling_Freshly_Isolated_CD44_Infrapatellar_Fat_Pad-Derived_Stromal_Cells_with_a_TGF-_3_Eluting_Cartilage_ECM-Derived_Scaffold_as_a_Single-Stage_Strategy_for_Promoting_Chondrogenesis_/10766417","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:tara.tcd.ie:2262/82240","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2262/82240","pdf_url":null,"source":{"id":"https://openalex.org/S4306400387","display_name":"Trinity's Access to Research Output (TARA) (Trinity College Dublin)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205274468","host_organization_name":"Trinity College Dublin","host_organization_lineage":["https://openalex.org/I205274468"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:http://www.rian.ie/146627/","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2262/82240","pdf_url":"http://hdl.handle.net/2262/82240","source":{"id":"https://openalex.org/S4306400033","display_name":"Arrow@dit (Dublin Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210144925","host_organization_name":"Technological University Dublin","host_organization_lineage":["https://openalex.org/I4210144925"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Almeida, A.V, Cunniffe, G.M., Vinardell, T., Buckley, C.T., O?Brien, F.J., Kelly, D.J., Coupling freshly isolated CD44+ infrapatellar fat pad derived stromal cells with a tgf-&amp;#946;3 eluting cartilage ecm-derived scaffold as a single stage strategy for promoting chondrogenesis., Advanced Healthcare Materials, 4, 7, 2015, 1043-1053","raw_type":"Journal article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320864","display_name":"Trinity College Dublin","ror":"https://ror.org/02tyrky19"},{"id":"https://openalex.org/F4320332194","display_name":"Johnson and Johnson","ror":"https://ror.org/03qd7mz70"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2098345480.pdf","grobid_xml":"https://content.openalex.org/works/W2098345480.grobid-xml"},"referenced_works_count":62,"referenced_works":["https://openalex.org/W422406947","https://openalex.org/W1197465675","https://openalex.org/W1800455829","https://openalex.org/W1923710437","https://openalex.org/W1968222609","https://openalex.org/W1974128523","https://openalex.org/W1974638778","https://openalex.org/W1979149897","https://openalex.org/W1993718448","https://openalex.org/W1996087228","https://openalex.org/W2000084305","https://openalex.org/W2002230244","https://openalex.org/W2003465548","https://openalex.org/W2008565536","https://openalex.org/W2018752568","https://openalex.org/W2020248562","https://openalex.org/W2021219047","https://openalex.org/W2026747501","https://openalex.org/W2032515788","https://openalex.org/W2039792565","https://openalex.org/W2041016801","https://openalex.org/W2046425583","https://openalex.org/W2047803062","https://openalex.org/W2050192951","https://openalex.org/W2051400613","https://openalex.org/W2057685431","https://openalex.org/W2059912755","https://openalex.org/W2060657670","https://openalex.org/W2063931687","https://openalex.org/W2071167287","https://openalex.org/W2072079099","https://openalex.org/W2072366127","https://openalex.org/W2072712108","https://openalex.org/W2074528940","https://openalex.org/W2074895129","https://openalex.org/W2077515150","https://openalex.org/W2078594660","https://openalex.org/W2078828283","https://openalex.org/W2081619465","https://openalex.org/W2083251136","https://openalex.org/W2084849128","https://openalex.org/W2084917141","https://openalex.org/W2093453395","https://openalex.org/W2101471690","https://openalex.org/W2104360963","https://openalex.org/W2105364331","https://openalex.org/W2110477578","https://openalex.org/W2115023398","https://openalex.org/W2116831801","https://openalex.org/W2120267080","https://openalex.org/W2123772237","https://openalex.org/W2127471027","https://openalex.org/W2128174450","https://openalex.org/W2142720627","https://openalex.org/W2144492173","https://openalex.org/W2146582187","https://openalex.org/W2147220928","https://openalex.org/W2152861671","https://openalex.org/W2155900557","https://openalex.org/W2160991148","https://openalex.org/W2161230998","https://openalex.org/W2326254565"],"related_works":["https://openalex.org/W2115023398","https://openalex.org/W3139558220","https://openalex.org/W2263013034","https://openalex.org/W7017706874","https://openalex.org/W3119213906","https://openalex.org/W2072079099","https://openalex.org/W2105364331","https://openalex.org/W2057685431","https://openalex.org/W2971154836","https://openalex.org/W2027740838"],"abstract_inverted_index":{"An":[0],"alternative":[1],"strategy":[2],"to":[3,28,33,46,79,124,161],"the":[4,15,57,103],"use":[5,16],"of":[6,17,42,63,73,85,94,105,172],"in":[7,11,38,115,146,176],"vitro":[8],"expanded":[9,158],"cells":[10,99,169],"regenerative":[12],"medicine":[13],"is":[14,26,45,77,121],"freshly":[18,64,127,163],"isolated":[19,65,128,164],"stromal":[20,66,131,168],"cells,":[21,132,165],"where":[22],"a":[23,48,83,135,149,174],"bioactive":[24],"scaffold":[25,53],"used":[27],"provide":[29],"an":[30],"environment":[31],"conducive":[32],"proliferation":[34,59],"and":[35,60,91,183],"tissue-specific":[36],"differentiation":[37,62,93],"vivo.":[39,147],"The":[40,88],"objective":[41],"this":[43],"study":[44],"develop":[47],"cartilage":[49,71],"extracellular":[50],"matrix":[51],"(ECM)-derived":[52],"that":[54,178],"could":[55,143,153],"facilitate":[56],"rapid":[58],"chondrogenic":[61,92],"cells.":[67],"By":[68],"freeze-drying":[69],"cryomilled":[70],"ECM":[72],"differing":[74],"concentrations,":[75],"it":[76],"possible":[78],"produce":[80],"scaffolds":[81,116],"with":[82,108,117],"range":[84],"pore":[86],"sizes.":[87],"migration,":[89],"proliferation,":[90],"infrapatellar":[95],"fat":[96,129],"pad-derived":[97,130],"stem":[98],"(FPSCs)":[100],"depend":[101],"on":[102],"concentration/porosity":[104],"these":[106],"scaffolds,":[107],"greater":[109],"sulphated":[110],"glycosaminoglycan":[111],"(sGAG)":[112],"accumulation":[113],"observed":[114],"larger-sized":[118],"pores.":[119],"It":[120],"then":[122],"sought":[123],"determine":[125],"if":[126],"seeded":[133],"onto":[134],"transforming":[136],"growth":[137],"factor":[138],"(TGF)-\u03b23":[139],"eluting":[140],"ECM-derived":[141],"scaffold,":[142],"promote":[144],"chondrogenesis":[145],"While":[148],"more":[150],"cartilage-like":[151],"tissue":[152,175],"be":[154],"generated":[155],"using":[156],"culture":[157],"FPSCs":[159],"compared":[160],"nonenriched":[162],"fresh":[166],"CD44(+)":[167],"are":[170],"capable":[171],"producing":[173],"vivo":[177],"stained":[179],"strongly":[180],"for":[181,193,197],"sGAGs":[182],"type":[184],"II":[185],"collagen.":[186],"These":[187],"findings":[188],"open":[189],"up":[190],"new":[191],"possibilities":[192],"in-theatre":[194],"cell-based":[195],"therapies":[196],"joint":[198],"regeneration.":[199]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":10},{"year":2018,"cited_by_count":12},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}
