{"id":"https://openalex.org/W2098153293","doi":"https://doi.org/10.1002/jmv.23810","title":"Cellular interplay among Th17, Th1, and Treg cells in HIV\u20101 subtype \u201cC\u201d infection","display_name":"Cellular interplay among Th17, Th1, and Treg cells in HIV\u20101 subtype \u201cC\u201d infection","publication_year":2013,"publication_date":"2013-11-19","ids":{"openalex":"https://openalex.org/W2098153293","doi":"https://doi.org/10.1002/jmv.23810","mag":"2098153293","pmid":"https://pubmed.ncbi.nlm.nih.gov/24249618"},"language":"en","primary_location":{"id":"doi:10.1002/jmv.23810","doi":"https://doi.org/10.1002/jmv.23810","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jmv.23810","pdf_url":null,"source":{"id":"https://openalex.org/S49828768","display_name":"Journal of Medical Virology","issn_l":"0146-6615","issn":["0146-6615","1096-9071"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medical Virology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044848727","display_name":"Alpana Singh","orcid":"https://orcid.org/0000-0001-6532-8654","observed_orcids":["https://orcid.org/0000-0001-6532-8654"]},"institutions":[{"id":"https://openalex.org/I464993","display_name":"Barkatullah University","ror":"https://ror.org/02ax13658","country_code":"IN","type":"education","lineage":["https://openalex.org/I464993"]},{"id":"https://openalex.org/I63739035","display_name":"All India Institute of Medical Sciences","ror":"https://ror.org/02dwcqs71","country_code":"IN","type":"education","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210148677","https://openalex.org/I63739035"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Alpana Singh","raw_affiliation_strings":["Department of Microbiology; All India Institute of Medical Sciences; New Delhi India","Saifia College of Science; Barkatullah University; Bhopal India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology; All India Institute of Medical Sciences; New Delhi India","institution_ids":["https://openalex.org/I63739035"]},{"raw_affiliation_string":"Saifia College of Science; Barkatullah University; Bhopal India","institution_ids":["https://openalex.org/I464993"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113589754","display_name":"Madhu Vajpayee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63739035","display_name":"All India Institute of Medical Sciences","ror":"https://ror.org/02dwcqs71","country_code":"IN","type":"education","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210148677","https://openalex.org/I63739035"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Madhu Vajpayee","raw_affiliation_strings":["Department of Microbiology, All India Institute of Medical Sciences, New Delhi, INDIA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, All India Institute of Medical Sciences, New Delhi, INDIA","institution_ids":["https://openalex.org/I63739035"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108003053","display_name":"Sharique A. Ali","orcid":"https://orcid.org/0000-0003-4143-6380","observed_orcids":["https://orcid.org/0000-0003-4143-6380"]},"institutions":[{"id":"https://openalex.org/I464993","display_name":"Barkatullah University","ror":"https://ror.org/02ax13658","country_code":"IN","type":"education","lineage":["https://openalex.org/I464993"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Sharique A. Ali","raw_affiliation_strings":["Saifia College of Science, Barkatullah University, Bhopal, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Saifia College of Science, Barkatullah University, Bhopal, India","institution_ids":["https://openalex.org/I464993"]}]},{"author_position":"last","author":{"id":null,"display_name":"Neeraj Kumar Chauhan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63739035","display_name":"All India Institute of Medical Sciences","ror":"https://ror.org/02dwcqs71","country_code":"IN","type":"education","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210148677","https://openalex.org/I63739035"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Neeraj Kumar Chauhan","raw_affiliation_strings":["Department of Microbiology, All India Institute of Medical Sciences, New Delhi, INDIA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, All India Institute of Medical Sciences, New Delhi, INDIA","institution_ids":["https://openalex.org/I63739035"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5113589754"],"corresponding_institution_ids":["https://openalex.org/I63739035"],"apc_list":{"value":4730,"currency":"USD","value_usd":4730},"apc_paid":null,"fwci":1.0123,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.71833273,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"86","issue":"3","first_page":"372","last_page":"384"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11655","display_name":"HIV-related health complications and treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hiv-1-subtype-c","display_name":"HIV-1 subtype C","score":0.949999988079071},{"id":"https://openalex.org/keywords/th17-cells","display_name":"Th17 cells","score":0.9629999995231628},{"id":"https://openalex.org/keywords/th1-cells","display_name":"Th1 cells","score":0.9959999918937683},{"id":"https://openalex.org/keywords/regulatory-t-cells","display_name":"regulatory T cells","score":0.9739999771118164},{"id":"https://openalex.org/keywords/cd4-t-cell-depletion","display_name":"CD4+ T cell depletion","score":0.9110000133514404},{"id":"https://openalex.org/keywords/hiv-disease-progression","display_name":"HIV disease progression","score":0.7149999737739563},{"id":"https://openalex.org/keywords/slow-progressors","display_name":"slow progressors","score":0.9110000133514404},{"id":"https://openalex.org/keywords/th17-treg-ratio","display_name":"Th17/Treg ratio","score":0.925000011920929},{"id":"https://openalex.org/keywords/plasma-viral-load","display_name":"plasma viral load","score":0.8180000185966492},{"id":"https://openalex.org/keywords/immune-activation","display_name":"immune activation","score":0.9779999852180481},{"id":"https://openalex.org/keywords/hiv-immunopathogenesis","display_name":"HIV immunopathogenesis","score":0.7229999899864197}],"concepts":[{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.7019890546798706},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6922987699508667},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.590324878692627},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5354360342025757},{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.5070304870605469},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5067787766456604},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5031618475914001},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.45614951848983765},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.4294966757297516},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.29748469591140747},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0557388961315155}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D016176","descriptor_name":"T-Lymphocyte Subsets","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D018417","descriptor_name":"Th1 Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D019562","descriptor_name":"Viral Load","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020276","descriptor_name":"HIV Long-Term Survivors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050378","descriptor_name":"T-Lymphocytes, Regulatory","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D054301","descriptor_name":"gag Gene Products, Human Immunodeficiency Virus","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D058504","descriptor_name":"Th17 Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1002/jmv.23810","doi":"https://doi.org/10.1002/jmv.23810","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jmv.23810","pdf_url":null,"source":{"id":"https://openalex.org/S49828768","display_name":"Journal of Medical Virology","issn_l":"0146-6615","issn":["0146-6615","1096-9071"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medical Virology","raw_type":"journal-article"},{"id":"pmid:24249618","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24249618","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of medical virology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320320720","display_name":"Indian Council of Medical Research","ror":"https://ror.org/0492wrx28"},{"id":"https://openalex.org/F4320324337","display_name":"All-India Institute of Medical Sciences","ror":"https://ror.org/02dwcqs71"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":50,"referenced_works":["https://openalex.org/W320714528","https://openalex.org/W1515986708","https://openalex.org/W1560155944","https://openalex.org/W1963958510","https://openalex.org/W1964728054","https://openalex.org/W1967168398","https://openalex.org/W1968276891","https://openalex.org/W1980484677","https://openalex.org/W1988384290","https://openalex.org/W1993569617","https://openalex.org/W1999839870","https://openalex.org/W2004998289","https://openalex.org/W2005227771","https://openalex.org/W2006249161","https://openalex.org/W2016488838","https://openalex.org/W2018002636","https://openalex.org/W2021812067","https://openalex.org/W2022760428","https://openalex.org/W2024490058","https://openalex.org/W2025482559","https://openalex.org/W2030001166","https://openalex.org/W2030883261","https://openalex.org/W2037259928","https://openalex.org/W2042393966","https://openalex.org/W2053110653","https://openalex.org/W2054523235","https://openalex.org/W2056020458","https://openalex.org/W2056029392","https://openalex.org/W2082546920","https://openalex.org/W2084744825","https://openalex.org/W2089940207","https://openalex.org/W2103179250","https://openalex.org/W2104167354","https://openalex.org/W2106471879","https://openalex.org/W2107235439","https://openalex.org/W2108832734","https://openalex.org/W2115756855","https://openalex.org/W2116516945","https://openalex.org/W2119546576","https://openalex.org/W2121030369","https://openalex.org/W2123797012","https://openalex.org/W2132926599","https://openalex.org/W2138165790","https://openalex.org/W2143589197","https://openalex.org/W2144979694","https://openalex.org/W2155779547","https://openalex.org/W2162819001","https://openalex.org/W2172466148","https://openalex.org/W2409861424","https://openalex.org/W2417924164"],"related_works":["https://openalex.org/W2317240150","https://openalex.org/W2087507850","https://openalex.org/W1985145772","https://openalex.org/W2013835161","https://openalex.org/W2029147028","https://openalex.org/W2256773660","https://openalex.org/W2103179250","https://openalex.org/W2138917364","https://openalex.org/W7096409996","https://openalex.org/W2523159349"],"abstract_inverted_index":{"CD4":[0,15],"T":[1,16],"cell":[2,165],"depletion":[3],"is":[4,40],"central":[5],"to":[6,19,85,108,115,119,139,157,196],"HIV":[7,37],"pathogenesis":[8],"and":[9,30,67,89,125,163,205],"disease":[10,104,135,200],"progression.":[11],"Different":[12],"subsets":[13,180],"of":[14,47,53,96,142,177,191],"cells":[17,32,55,76,98,112],"cooperate":[18],"combat":[20],"an":[21,154],"infection.":[22,121,144,186],"Therefore,":[23],"the":[24,51,64,93,175],"immune":[25,206],"balance":[26],"among":[27],"Th17,":[28],"Th1,":[29],"Treg":[31,129,171],"may":[33],"be":[34,116,197],"critical":[35],"in":[36,56,63,80,128,181],"immunopathogenesis":[38],"which":[39],"not":[41],"adequately":[42],"defined":[43],"yet.":[44],"The":[45],"impact":[46],"HIV-1":[48,57,70,103,120,143,160,185],"infection":[49],"on":[50],"interplay":[52],"Th17/Th1/Treg":[54],"infected":[58,82,87],"Indian":[59],"individuals":[60],"was":[61,99,132,194],"examined":[62],"present":[65],"study":[66,146],"report":[68],"that":[69,149],"Gag":[71],"specific":[72,161],"peripheral":[73],"blood":[74],"Th17":[75,109,162],"were":[77,113],"significantly":[78],"depleted":[79],"late":[81,140],"subjects,":[83],"compared":[84],"early":[86,138],"subjects":[88],"slow":[90,150],"progressors.":[91],"Although,":[92],"gradual":[94,189],"loss":[95,190],"Th1":[97,111,164],"also":[100,147],"reported":[101],"during":[102],"progression":[105],"but":[106],"relative":[107],"cells,":[110],"found":[114,195],"more":[117],"resistant":[118],"Additionally,":[122],"a":[123,169],"significant":[124,188],"progressive":[126,182],"gain":[127],"cellular":[130,172,179],"frequency":[131],"observed":[133],"as":[134],"progress":[136],"from":[137],"stage":[141],"This":[145],"indicate":[148],"progressors":[151],"might":[152],"have":[153],"intrinsic":[155],"capacity":[156],"develop":[158],"strong":[159],"responses":[166],"contrasted":[167],"with":[168,199],"faint":[170],"performance":[173],"signifies":[174],"importance":[176],"these":[178],"versus":[183],"nonprogressive":[184],"A":[187],"Th17/Treg":[192],"ratio":[193],"associated":[198],"state,":[201],"plasma":[202],"viral":[203],"load":[204],"activation.":[207]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}