{"id":"https://openalex.org/W2097704236","doi":null,"title":"Alcohol's effects on male reproduction.","display_name":"Alcohol's effects on male reproduction.","publication_year":1998,"publication_date":"1998-01-01","ids":{"openalex":"https://openalex.org/W2097704236","mag":"2097704236","pmid":"https://pubmed.ncbi.nlm.nih.gov/15706796","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6761906"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:5733235","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6761906","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6761906","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010484029","display_name":"Mary Ann Emanuele","orcid":"https://orcid.org/0000-0002-0074-2667","observed_orcids":["https://orcid.org/0000-0002-0074-2667"]},"institutions":[{"id":"https://openalex.org/I1304196042","display_name":"Loyola University Medical Center","ror":"https://ror.org/05xcyt367","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1304196042","https://openalex.org/I1304269903"]},{"id":"https://openalex.org/I1925986","display_name":"Loyola University Chicago","ror":"https://ror.org/04b6x2g63","country_code":"US","type":"education","lineage":["https://openalex.org/I1925986"]},{"id":"https://openalex.org/I4210159390","display_name":"Loyola Medicine","ror":"https://ror.org/04azs9g49","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210159390"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M A Emanuele","raw_affiliation_strings":["Department of Medicine, Division of Research on Drugs of Abuse, Loyola University Stritch School of Medicine, Maywood, Illinois, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Division of Research on Drugs of Abuse, Loyola University Stritch School of Medicine, Maywood, Illinois, USA","institution_ids":["https://openalex.org/I1304196042","https://openalex.org/I1925986","https://openalex.org/I4210159390"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112773383","display_name":"N. V. Emanuele","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N V Emanuele","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4427,"has_fulltext":false,"cited_by_count":137,"citation_normalized_percentile":{"value":0.58410175,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"22","issue":"3","first_page":"195","last_page":"201"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.8535000085830688,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.8535000085830688,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11207","display_name":"Alcohol Consumption and Health Effects","score":0.0966000035405159,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.01979999989271164,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alcohol-consumption","display_name":"alcohol consumption","score":0.8320000171661377},{"id":"https://openalex.org/keywords/male-reproduction","display_name":"male reproduction","score":0.9269999861717224},{"id":"https://openalex.org/keywords/erectile-dysfunction","display_name":"erectile dysfunction","score":0.7329999804496765},{"id":"https://openalex.org/keywords/male-infertility","display_name":"male infertility","score":0.9269999861717224},{"id":"https://openalex.org/keywords/testosterone","display_name":"testosterone","score":0.574999988079071},{"id":"https://openalex.org/keywords/leydig-cells","display_name":"Leydig cells","score":0.9980000257492065},{"id":"https://openalex.org/keywords/sertoli-cells","display_name":"Sertoli cells","score":0.9980000257492065},{"id":"https://openalex.org/keywords/luteinizing-hormone","display_name":"luteinizing hormone","score":0.8920000195503235},{"id":"https://openalex.org/keywords/follicle-stimulating-hormone","display_name":"follicle-stimulating hormone","score":1.0},{"id":"https://openalex.org/keywords/hypothalamus","display_name":"hypothalamus","score":0.9779999852180481},{"id":"https://openalex.org/keywords/pituitary-gland","display_name":"pituitary gland","score":0.8299999833106995},{"id":"https://openalex.org/keywords/secondary-sexual-characteristics","display_name":"secondary sexual characteristics","score":0.7089999914169312}],"concepts":[{"id":"https://openalex.org/C2778575703","wikidata":"https://www.wikidata.org/wiki/Q50265477","display_name":"Luteinizing hormone","level":3,"score":0.7499179840087891},{"id":"https://openalex.org/C2779279991","wikidata":"https://www.wikidata.org/wiki/Q6058681","display_name":"Testosterone (patch)","level":2,"score":0.7461296319961548},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.729387640953064},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7271703481674194},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.7077894806861877},{"id":"https://openalex.org/C2777003273","wikidata":"https://www.wikidata.org/wiki/Q164386","display_name":"Hypothalamus","level":2,"score":0.65340256690979},{"id":"https://openalex.org/C146819174","wikidata":"https://www.wikidata.org/wiki/Q1703595","display_name":"Hypothalamic\u2013pituitary\u2013gonadal axis","level":4,"score":0.5967634320259094},{"id":"https://openalex.org/C2779279165","wikidata":"https://www.wikidata.org/wiki/Q200774","display_name":"Follicle-stimulating hormone","level":4,"score":0.5327202081680298},{"id":"https://openalex.org/C123765429","wikidata":"https://www.wikidata.org/wiki/Q36961","display_name":"Spermatogenesis","level":2,"score":0.5062743425369263},{"id":"https://openalex.org/C2781068068","wikidata":"https://www.wikidata.org/wiki/Q195614","display_name":"Sertoli cell","level":3,"score":0.485561341047287},{"id":"https://openalex.org/C2781066024","wikidata":"https://www.wikidata.org/wiki/Q156","display_name":"Alcohol","level":2,"score":0.47349557280540466},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.45660901069641113},{"id":"https://openalex.org/C2777658017","wikidata":"https://www.wikidata.org/wiki/Q156871","display_name":"Pituitary gland","level":3,"score":0.4528322219848633},{"id":"https://openalex.org/C59659247","wikidata":"https://www.wikidata.org/wiki/Q11990","display_name":"Reproduction","level":2,"score":0.41040802001953125},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.25433820486068726},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000428","descriptor_name":"Alcohol Drinking","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D000428","descriptor_name":"Alcohol Drinking","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D000431","descriptor_name":"Ethanol","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005298","descriptor_name":"Fertility","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D005298","descriptor_name":"Fertility","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007248","descriptor_name":"Infertility, Male","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"pmh:oai:europepmc.org:5733235","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6761906","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6761906","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6761906","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alcohol Health Res World","raw_type":"Text"},{"id":"pmid:15706796","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15706796","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alcohol health and research world","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.613.9098","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.613.9098","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://pubs.niaaa.nih.gov/publications/arh22-3/195.pdf","raw_type":"text"},{"id":"mag:2097704236","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15706796","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:5733235","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6761906","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"score":0.9476000070571899,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W319104132","https://openalex.org/W1973249045","https://openalex.org/W1979851190","https://openalex.org/W1982561803","https://openalex.org/W1982832718","https://openalex.org/W2000047199","https://openalex.org/W2011252627","https://openalex.org/W2019533589","https://openalex.org/W2024054187","https://openalex.org/W2029598383","https://openalex.org/W2030427298","https://openalex.org/W2032711393","https://openalex.org/W2042462933","https://openalex.org/W2046976249","https://openalex.org/W2047485778","https://openalex.org/W2050590571","https://openalex.org/W2050950623","https://openalex.org/W2052218719","https://openalex.org/W2053271595","https://openalex.org/W2053856783","https://openalex.org/W2056277690","https://openalex.org/W2082439458","https://openalex.org/W2084564149","https://openalex.org/W2090614714","https://openalex.org/W2093108928","https://openalex.org/W2128963913","https://openalex.org/W2136223876","https://openalex.org/W2137060609","https://openalex.org/W2148079805","https://openalex.org/W2151800749","https://openalex.org/W2155826393","https://openalex.org/W2324927661","https://openalex.org/W2338841503","https://openalex.org/W2436850615","https://openalex.org/W4232307722","https://openalex.org/W4248885943"],"related_works":["https://openalex.org/W3034644824","https://openalex.org/W2378970648","https://openalex.org/W1547847868","https://openalex.org/W2085182364","https://openalex.org/W137472285","https://openalex.org/W2417935516","https://openalex.org/W145926599","https://openalex.org/W2328251235","https://openalex.org/W2351508642","https://openalex.org/W2134855344"],"abstract_inverted_index":{"The":[0],"male":[1,32],"reproductive":[2,102],"system":[3],"consists":[4],"of":[5,21,23,72,97],"the":[6,8,13,19,37,43,50,65,70,73,86,92,117],"hypothalamus,":[7],"anterior":[9],"pituitary":[10,87],"gland,":[11,88],"and":[12,30,48,106],"testes.":[14],"Alcohol":[15,67],"can":[16,40,90,111],"interfere":[17,112],"with":[18,100,113],"function":[20,71],"each":[22],"these":[24],"components,":[25],"thereby":[26],"causing":[27],"impotence,":[28],"infertility,":[29],"reduced":[31,61],"secondary":[33],"sexual":[34],"characteristics.":[35],"In":[36,85],"testes,":[38],"alcohol":[39,57,89,110],"adversely":[41],"affect":[42],"Leydig":[44],"cells,":[45],"which":[46],"produce":[47],"secrete":[49],"hormone":[51,105,114],"testosterone.":[52],"Studies":[53],"found":[54],"that":[55,77],"heavy":[56],"consumption":[58],"results":[59],"in":[60,64,82,116],"testosterone":[62],"levels":[63],"blood.":[66],"also":[68],"impairs":[69],"testicular":[74],"Sertoli":[75],"cells":[76],"play":[78],"an":[79],"important":[80],"role":[81],"sperm":[83],"maturation.":[84],"decrease":[91],"production,":[93],"release,":[94],"and/or":[95],"activity":[96],"two":[98],"hormones":[99],"critical":[101],"functions,":[103],"luteinizing":[104],"follicle-stimulating":[107],"hormone.":[108],"Finally,":[109],"production":[115],"hypothalamus.":[118]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":13},{"year":2013,"cited_by_count":8},{"year":2012,"cited_by_count":8}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}