{"id":"https://openalex.org/W2097631487","doi":"https://doi.org/10.1128/jvi.01549-10","title":"Evolution of Functional and Sequence Variants of the Mammalian XPR1 Receptor for Mouse Xenotropic Gammaretroviruses and the Human-Derived Retrovirus XMRV","display_name":"Evolution of Functional and Sequence Variants of the Mammalian XPR1 Receptor for Mouse Xenotropic Gammaretroviruses and the Human-Derived Retrovirus XMRV","publication_year":2010,"publication_date":"2010-09-16","ids":{"openalex":"https://openalex.org/W2097631487","doi":"https://doi.org/10.1128/jvi.01549-10","mag":"2097631487","pmid":"https://pubmed.ncbi.nlm.nih.gov/20844050","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2977887"},"language":"en","primary_location":{"id":"doi:10.1128/jvi.01549-10","doi":"https://doi.org/10.1128/jvi.01549-10","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jvi.01549-10","pdf_url":null,"source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2977887","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103704998","display_name":"Yuhe Yan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yuhe Yan","raw_affiliation_strings":["Laboratory of Molecular Microbiology","NIH, NIAID, LMM, Bldg. 4, Room 329, 4 Center Drive MSC 0460, Bethesda, MD 20892-0460"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Microbiology","institution_ids":[]},{"raw_affiliation_string":"NIH, NIAID, LMM, Bldg. 4, Room 329, 4 Center Drive MSC 0460, Bethesda, MD 20892-0460","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101415721","display_name":"Qingping Liu","orcid":"https://orcid.org/0000-0002-8347-3123","observed_orcids":["https://orcid.org/0000-0002-8347-3123"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Qingping Liu","raw_affiliation_strings":["Laboratory of Molecular Microbiology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Microbiology","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060237361","display_name":"Kurt R. Wollenberg","orcid":"https://orcid.org/0000-0002-4973-9370","observed_orcids":["https://orcid.org/0000-0002-4973-9370"]},"institutions":[{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kurt Wollenberg","raw_affiliation_strings":["Bioinformatics and Computational Biosciences Branch, Office of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinformatics and Computational Biosciences Branch, Office of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892","institution_ids":["https://openalex.org/I4210134534"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Carrie Martin","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Carrie Martin","raw_affiliation_strings":["Laboratory of Molecular Microbiology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Microbiology","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089354143","display_name":"Alicia J. Buckler-White","orcid":"https://orcid.org/0000-0003-3357-0328","observed_orcids":["https://orcid.org/0000-0003-3357-0328"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alicia Buckler-White","raw_affiliation_strings":["Laboratory of Molecular Microbiology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Microbiology","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034224042","display_name":"Christine A. Kozak","orcid":"https://orcid.org/0000-0001-5863-6915","observed_orcids":["https://orcid.org/0000-0001-5863-6915"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Christine A. Kozak","raw_affiliation_strings":["Laboratory of Molecular Microbiology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Microbiology","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5034224042"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.1552,"has_fulltext":false,"cited_by_count":41,"citation_normalized_percentile":{"value":0.92455452,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"84","issue":"22","first_page":"11970","last_page":"11980"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11764","display_name":"Evolution and Genetic Dynamics","score":0.5878999829292297,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11764","display_name":"Evolution and Genetic Dynamics","score":0.5878999829292297,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12654","display_name":"Xenotransplantation and immune response","score":0.15360000729560852,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12159","display_name":"T-cell and Retrovirus Studies","score":0.09780000150203705,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/xmrv","display_name":"XMRV","score":0.7820000052452087},{"id":"https://openalex.org/keywords/gammaretrovirus","display_name":"gammaretrovirus","score":0.8920000195503235},{"id":"https://openalex.org/keywords/host-virus-coevolution","display_name":"host-virus coevolution","score":0.7889999747276306},{"id":"https://openalex.org/keywords/receptor-evolution","display_name":"receptor evolution","score":0.5320000052452087},{"id":"https://openalex.org/keywords/positive-selection","display_name":"positive selection","score":0.7900000214576721},{"id":"https://openalex.org/keywords/virus-entry","display_name":"viral entry","score":0.47099998593330383},{"id":"https://openalex.org/keywords/mus-musculus","display_name":"Mus musculus","score":0.6859999895095825},{"id":"https://openalex.org/keywords/hamster","display_name":"hamster","score":0.5149999856948853},{"id":"https://openalex.org/keywords/gerbils","display_name":"gerbils","score":0.9649999737739563},{"id":"https://openalex.org/keywords/cross-species-transmission","display_name":"interspecies transmission","score":0.6759999990463257},{"id":"https://openalex.org/keywords/chronic-fatigue-syndrome","display_name":"chronic fatigue syndrome","score":0.621999979019165},{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.9850000143051147}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9229806661605835},{"id":"https://openalex.org/C2776130206","wikidata":"https://www.wikidata.org/wiki/Q636512","display_name":"Gammaretrovirus","level":4,"score":0.8147401213645935},{"id":"https://openalex.org/C2779562191","wikidata":"https://www.wikidata.org/wiki/Q673848","display_name":"Murine leukemia virus","level":3,"score":0.8114039897918701},{"id":"https://openalex.org/C2778431562","wikidata":"https://www.wikidata.org/wiki/Q189308","display_name":"Retrovirus","level":3,"score":0.753822922706604},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.6335389018058777},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.6251628398895264},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6045840382575989},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.4332926273345947},{"id":"https://openalex.org/C16318435","wikidata":"https://www.wikidata.org/wiki/Q149299","display_name":"Mutagenesis","level":4,"score":0.415979266166687},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.4115198254585266},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3305889964103699}],"mesh":[{"descriptor_ui":"D000089842","descriptor_name":"Xenotropic and Polytropic Retrovirus Receptor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006041","descriptor_name":"Goats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006168","descriptor_name":"Guinea Pigs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006224","descriptor_name":"Cricetinae","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008322","descriptor_name":"Mammals","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008322","descriptor_name":"Mammals","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008322","descriptor_name":"Mammals","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009052","descriptor_name":"Leukemia Virus, Murine","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D009052","descriptor_name":"Leukemia Virus, Murine","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009052","descriptor_name":"Leukemia Virus, Murine","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D009052","descriptor_name":"Leukemia Virus, Murine","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011991","descriptor_name":"Receptors, Virus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D011991","descriptor_name":"Receptors, Virus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012192","descriptor_name":"Retroviridae Infections","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012192","descriptor_name":"Retroviridae Infections","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012192","descriptor_name":"Retroviridae Infections","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":true},{"descriptor_ui":"D012192","descriptor_name":"Retroviridae Infections","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017988","descriptor_name":"Gammaretrovirus","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D017988","descriptor_name":"Gammaretrovirus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017988","descriptor_name":"Gammaretrovirus","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D017988","descriptor_name":"Gammaretrovirus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1128/jvi.01549-10","doi":"https://doi.org/10.1128/jvi.01549-10","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jvi.01549-10","pdf_url":null,"source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2977887","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2977887","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Virol","raw_type":"Text"},{"id":"pmid:20844050","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20844050","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of virology","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.905.8348","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.905.8348","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://jvi.asm.org/content/84/22/11970.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2977887","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2977887","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Virol","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5683000087738037}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W160633832","https://openalex.org/W176539372","https://openalex.org/W791550880","https://openalex.org/W1492157159","https://openalex.org/W1494887493","https://openalex.org/W1518293425","https://openalex.org/W1541422616","https://openalex.org/W1557108213","https://openalex.org/W1630972086","https://openalex.org/W1780495873","https://openalex.org/W1810475892","https://openalex.org/W1838615456","https://openalex.org/W1980231518","https://openalex.org/W1981305861","https://openalex.org/W1982728840","https://openalex.org/W1983496980","https://openalex.org/W1988040437","https://openalex.org/W1989874218","https://openalex.org/W1998971747","https://openalex.org/W2011832001","https://openalex.org/W2015091053","https://openalex.org/W2025896212","https://openalex.org/W2026087575","https://openalex.org/W2037886449","https://openalex.org/W2047491231","https://openalex.org/W2063309550","https://openalex.org/W2063905114","https://openalex.org/W2070609589","https://openalex.org/W2076193053","https://openalex.org/W2092764876","https://openalex.org/W2100316327","https://openalex.org/W2104841123","https://openalex.org/W2106403625","https://openalex.org/W2112461060","https://openalex.org/W2124673802","https://openalex.org/W2129588663","https://openalex.org/W2130108070","https://openalex.org/W2132926880","https://openalex.org/W2136693006","https://openalex.org/W2139319495","https://openalex.org/W2148294875","https://openalex.org/W2149819696","https://openalex.org/W2160675481","https://openalex.org/W2162593834","https://openalex.org/W2164341121","https://openalex.org/W2165474398","https://openalex.org/W2168222953","https://openalex.org/W2170565120","https://openalex.org/W2188716564","https://openalex.org/W2291863532","https://openalex.org/W2337564029","https://openalex.org/W2338885917","https://openalex.org/W2481332952","https://openalex.org/W2588914676","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W7099187514","https://openalex.org/W2165474398","https://openalex.org/W1969515878","https://openalex.org/W2112461060","https://openalex.org/W7095564489","https://openalex.org/W2092338730","https://openalex.org/W2497862787","https://openalex.org/W2119136341","https://openalex.org/W2036953780","https://openalex.org/W2954694128"],"abstract_inverted_index":{"Genetic":[0],"conflicts":[1],"between":[2],"retroviruses":[3],"and":[4,16,20,30,57,63,80,99,109,116,140,152,194,199,243,245],"their":[5],"receptors":[6],"result":[7],"in":[8,36,97,106,133,174,254,261,270],"the":[9,37,41,54,92,114,120,128,145,191,195,214,255],"evolution":[10],"of":[11,53,119,164,190,197,251],"novel":[12,17,101,236],"host":[13],"entry":[14,241],"restrictions":[15],"virus":[18,73,175,240],"envelopes,":[19],"such":[21],"variants":[22,96,123,259],"can":[23],"influence":[24],"trans-species":[25],"transmission.":[26],"We":[27,84,112,137,211],"screened":[28],"rodents":[29],"other":[31,188],"mammals":[32,179],"for":[33,40,58,239],"sequence":[34],"variation":[35,253],"Xpr1":[38,95,103,122,156,258],"receptor":[39,209,231,281],"mouse":[42,46,131,183],"xenotropic":[43],"or":[44,50,277],"polytropic":[45],"leukemia":[47,68],"viruses":[48],"(X-MLVs":[49],"P-MLVs,":[51],"respectively)":[52],"gammaretrovirus":[55],"family":[56],"susceptibility":[59,88],"to":[60,64,126,143,182,202,230],"mouse-derived":[61],"X/P-MLVs":[62],"XMRV":[65,203,206],"(xenotropic":[66],"murine":[67],"virus-related":[69],"virus),":[70],"an":[71],"X-MLV-like":[72],"isolated":[74],"from":[75],"humans":[76],"with":[77],"prostate":[78],"cancer":[79],"chronic":[81],"fatigue":[82],"syndrome.":[83],"identified":[85],"multiple":[86],"distinct":[87],"phenotypes;":[89],"these":[90,265,275],"include":[91],"four":[93],"known":[94,172],"Mus":[98,107,110,121],"a":[100,162,248],"fifth":[102],"gene":[104],"found":[105,260],"molossinus":[108],"musculus.":[111],"describe":[113,247],"geographic":[115],"species":[117],"distribution":[118],"but":[124,185],"failed":[125],"find":[127],"X-MLV-restrictive":[129],"laboratory":[130],"allele":[132],"any":[134],"wild":[135],"mouse.":[136],"used":[138],"mutagenesis":[139],"phylogenetic":[141],"analysis":[142],"evaluate":[144],"functional":[146],"contributions":[147],"made":[148],"by":[149],"constrained,":[150],"variable,":[151],"deleted":[153],"residues.":[154],"Rodent":[155],"is":[157],"under":[158,169],"positive":[159],"selection,":[160],"indicating":[161],"history":[163],"host-pathogen":[165],"conflicts;":[166],"several":[167],"codons":[168],"selection":[170],"have":[171],"roles":[173],"entry.":[176],"All":[177],"non-Mus":[178],"are":[180],"susceptible":[181],"X-MLVs,":[184],"some":[186],"restrict":[187],"members":[189],"X/P-MLV":[192],"family,":[193],"resistance":[196],"hamster":[198],"gerbil":[200],"cells":[201],"indicates":[204],"that":[205,213,226,274],"has":[207],"unique":[208,249],"requirements.":[210],"show":[212],"hypervariable":[215],"fourth":[216],"extracellular":[217],"XPR1":[218],"loop":[219,278],"(ECL4)":[220],"contains":[221],"three":[222,256],"evolutionarily":[223],"constrained":[224],"residues":[225,237],"do":[227],"not":[228],"contribute":[229],"function,":[232],"we":[233,246],"identify":[234],"two":[235],"important":[238],"(I579":[242],"T583),":[244],"pattern":[250],"ECL4":[252],"virus-restrictive":[257],"MLV-infected":[262],"house":[263],"mice;":[264],"mice":[266],"carry":[267],"different":[268],"deletions":[269],"ECL4,":[271],"suggesting":[272],"either":[273],"sites":[276],"size":[279],"affects":[280],"function.":[282]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}