{"id":"https://openalex.org/W2097367333","doi":"https://doi.org/10.1093/clinchem/34.11.2311","title":"Significance of low concentrations of creatinine in serum from hospital patients.","display_name":"Significance of low concentrations of creatinine in serum from hospital patients.","publication_year":1988,"publication_date":"1988-11-01","ids":{"openalex":"https://openalex.org/W2097367333","doi":"https://doi.org/10.1093/clinchem/34.11.2311","mag":"2097367333","pmid":"https://pubmed.ncbi.nlm.nih.gov/3180428"},"language":"en","primary_location":{"id":"doi:10.1093/clinchem/34.11.2311","doi":"https://doi.org/10.1093/clinchem/34.11.2311","is_oa":false,"landing_page_url":"https://doi.org/10.1093/clinchem/34.11.2311","pdf_url":null,"source":{"id":"https://openalex.org/S139212996","display_name":"Clinical Chemistry","issn_l":"0009-9147","issn":["0009-9147","1530-8561"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320272","host_organization_name":"American Association for Clinical Chemistry","host_organization_lineage":["https://openalex.org/P4310320272"],"host_organization_lineage_names":["American Association for Clinical Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112902411","display_name":"P Hagemann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210151503","display_name":"Spital Thurgau (Switzerland)","ror":"https://ror.org/04qnzk495","country_code":"CH","type":"company","lineage":["https://openalex.org/I4210151503"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"P Hagemann","raw_affiliation_strings":["Central Laboratory, Thurgau State Hospital, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Laboratory, Thurgau State Hospital, Switzerland","institution_ids":["https://openalex.org/I4210151503"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5060165537","display_name":"Sidney N. Kahn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210151503","display_name":"Spital Thurgau (Switzerland)","ror":"https://ror.org/04qnzk495","country_code":"CH","type":"company","lineage":["https://openalex.org/I4210151503"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"S N Kahn","raw_affiliation_strings":["Central Laboratory, Thurgau State Hospital, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Laboratory, Thurgau State Hospital, Switzerland","institution_ids":["https://openalex.org/I4210151503"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210151503"],"apc_list":{"value":4636,"currency":"USD","value_usd":4636},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":{"value":0.18687664,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"34","issue":"11","first_page":"2311","last_page":"2312"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11314","display_name":"Clinical Laboratory Practices and Quality Control","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/3607","display_name":"Medical Laboratory Technology"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11314","display_name":"Clinical Laboratory Practices and Quality Control","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/3607","display_name":"Medical Laboratory Technology"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12117","display_name":"Muscle and Compartmental Disorders","score":0.004600000102072954,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypereosinophilic-syndrome","display_name":"hypereosinophilic syndrome","score":0.6200000047683716},{"id":"https://openalex.org/keywords/enzymatic-creatinine-assay","display_name":"enzymatic creatinine assay","score":0.6330000162124634},{"id":"https://openalex.org/keywords/pregnancy","display_name":"pregnancy","score":0.9750000238418579},{"id":"https://openalex.org/keywords/type-1-diabetes","display_name":"type 1 diabetes","score":0.9710000157356262},{"id":"https://openalex.org/keywords/immobilization","display_name":"immobilization","score":0.800000011920929}],"concepts":[{"id":"https://openalex.org/C2780306776","wikidata":"https://www.wikidata.org/wiki/Q426660","display_name":"Creatinine","level":2,"score":0.9175870418548584},{"id":"https://openalex.org/C63363279","wikidata":"https://www.wikidata.org/wiki/Q5133848","display_name":"Clinical significance","level":2,"score":0.761962354183197},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6121932864189148},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.6053564548492432},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5891638398170471},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5150982737541199},{"id":"https://openalex.org/C159641895","wikidata":"https://www.wikidata.org/wiki/Q108377937","display_name":"Renal function","level":2,"score":0.5055384635925293},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5006721019744873},{"id":"https://openalex.org/C3020081911","wikidata":"https://www.wikidata.org/wiki/Q3918988","display_name":"Serum concentration","level":2,"score":0.41011959314346313},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.35775309801101685},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.3433615267276764},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003404","descriptor_name":"Creatinine","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007297","descriptor_name":"Inpatients","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D010243","descriptor_name":"Paralysis","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D010361","descriptor_name":"Patients","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D012016","descriptor_name":"Reference Values","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/clinchem/34.11.2311","doi":"https://doi.org/10.1093/clinchem/34.11.2311","is_oa":false,"landing_page_url":"https://doi.org/10.1093/clinchem/34.11.2311","pdf_url":null,"source":{"id":"https://openalex.org/S139212996","display_name":"Clinical Chemistry","issn_l":"0009-9147","issn":["0009-9147","1530-8561"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320272","host_organization_name":"American Association for Clinical Chemistry","host_organization_lineage":["https://openalex.org/P4310320272"],"host_organization_lineage_names":["American Association for Clinical Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Chemistry","raw_type":"journal-article"},{"id":"pmid:3180428","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3180428","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical chemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2282510475","https://openalex.org/W2036433474","https://openalex.org/W3084869096","https://openalex.org/W2284691378","https://openalex.org/W2418152647","https://openalex.org/W4290620979","https://openalex.org/W2040981474","https://openalex.org/W2408192692","https://openalex.org/W2038836331","https://openalex.org/W2741156344"],"abstract_inverted_index":{"We":[0,103],"present":[1],"an":[2,30],"analysis":[3,57],"of":[4,8,36,46,61,88,108],"the":[5,65,89,98],"clinical":[6,73,115],"significance":[7],"creatinine":[9,40,101,109],"concentrations":[10,41,107],"less":[11],"than":[12],"or":[13,51],"equal":[14],"to":[15],"4":[16],"mg/L":[17,48],"(35":[18],"mumol/L)":[19,50],"in":[20,110],"serum":[21,39,111],"as":[22],"measured":[23],"by":[24],"a":[25,44,59],"specific":[26],"enzymatic":[27],"method.":[28],"In":[29],"unselected":[31],"hospital":[32],"patient":[33],"population,":[34],"4%":[35],"whom":[37],"had":[38,68,93],"this":[42],"low,":[43],"value":[45],"5":[47],"(44":[49],"higher":[52],"was":[53],"obtained":[54],"on":[55],"repeat":[56],"for":[58,97],"third":[60],"these":[62],"patients,":[63,90],"but":[64,86],"remaining":[66],"two-thirds":[67],"persistently":[69,99],"low":[70,76,100,106],"values.":[71],"Associated":[72],"conditions":[74],"included":[75],"body":[77],"mass,":[78],"pregnancy,":[79],"insulin-dependent":[80],"diabetes":[81],"mellitus,":[82],"and":[83],"total":[84],"immobilization,":[85],"12%":[87],"all":[91],"female,":[92],"no":[94,113],"obvious":[95],"cause":[96],"concentration.":[102],"conclude":[104],"that":[105],"have":[112],"profound":[114],"significance.":[116]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}