{"id":"https://openalex.org/W2097356993","doi":"https://doi.org/10.1002/dc.21363","title":"Interobserver variability amongst cytopathologists and histopathologists in the diagnosis of neoplastic follicular patterned lesions of thyroid","display_name":"Interobserver variability amongst cytopathologists and histopathologists in the diagnosis of neoplastic follicular patterned lesions of thyroid","publication_year":2010,"publication_date":"2010-05-06","ids":{"openalex":"https://openalex.org/W2097356993","doi":"https://doi.org/10.1002/dc.21363","mag":"2097356993","pmid":"https://pubmed.ncbi.nlm.nih.gov/21416635"},"language":"en","primary_location":{"id":"doi:10.1002/dc.21363","doi":"https://doi.org/10.1002/dc.21363","is_oa":false,"landing_page_url":"https://doi.org/10.1002/dc.21363","pdf_url":null,"source":{"id":"https://openalex.org/S23314063","display_name":"Diagnostic Cytopathology","issn_l":"1097-0339","issn":["1097-0339","8755-1039"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diagnostic Cytopathology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109543230","display_name":"Rajan Duggal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I45294948","display_name":"Post Graduate Institute of Medical Education and Research","ror":"https://ror.org/009nfym65","country_code":"IN","type":"education","lineage":["https://openalex.org/I45294948"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Rajan Duggal","raw_affiliation_strings":["Department of Cytology and Gynecologic Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cytology and Gynecologic Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India","institution_ids":["https://openalex.org/I45294948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109896284","display_name":"Arvind Rajwanshi","orcid":"https://orcid.org/0000-0003-2877-7818","observed_orcids":["https://orcid.org/0000-0003-2877-7818"]},"institutions":[{"id":"https://openalex.org/I45294948","display_name":"Post Graduate Institute of Medical Education and Research","ror":"https://ror.org/009nfym65","country_code":"IN","type":"education","lineage":["https://openalex.org/I45294948"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Arvind Rajwanshi","raw_affiliation_strings":["Department of Cytology and Gynecologic Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cytology and Gynecologic Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India","institution_ids":["https://openalex.org/I45294948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040516726","display_name":"Nalini Gupta","orcid":"https://orcid.org/0000-0003-3385-1955","observed_orcids":["https://orcid.org/0000-0003-3385-1955"]},"institutions":[{"id":"https://openalex.org/I45294948","display_name":"Post Graduate Institute of Medical Education and Research","ror":"https://ror.org/009nfym65","country_code":"IN","type":"education","lineage":["https://openalex.org/I45294948"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Nalini Gupta","raw_affiliation_strings":["Department of Cytology and Gynecologic Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cytology and Gynecologic Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India","institution_ids":["https://openalex.org/I45294948"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113850641","display_name":"Rakesh Kumar Vasishta","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I45294948","display_name":"Post Graduate Institute of Medical Education and Research","ror":"https://ror.org/009nfym65","country_code":"IN","type":"education","lineage":["https://openalex.org/I45294948"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Rakesh Kumar Vasishta,","raw_affiliation_strings":["Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India","institution_ids":["https://openalex.org/I45294948"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5109896284"],"corresponding_institution_ids":["https://openalex.org/I45294948"],"apc_list":{"value":3920,"currency":"USD","value_usd":3920},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":20,"citation_normalized_percentile":{"value":0.21320167,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"39","issue":"4","first_page":"235","last_page":"241"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10329","display_name":"Thyroid Cancer Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10329","display_name":"Thyroid Cancer Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11728","display_name":"Thyroid and Parathyroid Surgery","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13309","display_name":"Reliability and Agreement in Measurement","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1804","display_name":"Statistics, Probability and Uncertainty"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interobserver-variability","display_name":"interobserver variability","score":0.902999997138977},{"id":"https://openalex.org/keywords/hurthle-cell-neoplasm","display_name":"H\u00fcrthle cell neoplasm","score":0.8090000152587891},{"id":"https://openalex.org/keywords/follicular-variant-of-papillary-thyroid-carcinoma","display_name":"follicular variant of papillary thyroid carcinoma","score":0.9179999828338623},{"id":"https://openalex.org/keywords/follicular-thyroid-adenoma","display_name":"follicular adenoma","score":0.7020000219345093},{"id":"https://openalex.org/keywords/overdiagnosis","display_name":"overdiagnosis","score":0.7549999952316284},{"id":"https://openalex.org/keywords/diagnostic-accuracy","display_name":"diagnostic accuracy","score":0.7879999876022339},{"id":"https://openalex.org/keywords/thyroid-cytology","display_name":"thyroid cytology","score":0.6539999842643738}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8546479940414429},{"id":"https://openalex.org/C544855455","wikidata":"https://www.wikidata.org/wiki/Q1070952","display_name":"Histopathology","level":2,"score":0.8438922166824341},{"id":"https://openalex.org/C18823058","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cytology","level":2,"score":0.6871945261955261},{"id":"https://openalex.org/C2778654104","wikidata":"https://www.wikidata.org/wiki/Q1881849","display_name":"Cytopathology","level":3,"score":0.5724893808364868},{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.5190597176551819},{"id":"https://openalex.org/C534262118","wikidata":"https://www.wikidata.org/wiki/Q177719","display_name":"Medical diagnosis","level":2,"score":0.5151268243789673},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.4941463768482208},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.4862914979457855},{"id":"https://openalex.org/C194495517","wikidata":"https://www.wikidata.org/wiki/Q7646222","display_name":"Surgical pathology","level":2,"score":0.4780355393886566},{"id":"https://openalex.org/C2777428134","wikidata":"https://www.wikidata.org/wiki/Q272741","display_name":"Adenoma","level":2,"score":0.447797954082489},{"id":"https://openalex.org/C2780635560","wikidata":"https://www.wikidata.org/wiki/Q1216998","display_name":"Neoplasm","level":2,"score":0.41592735052108765},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.09603023529052734}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002291","descriptor_name":"Carcinoma, Papillary","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D002291","descriptor_name":"Carcinoma, Papillary","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002291","descriptor_name":"Carcinoma, Papillary","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D003937","descriptor_name":"Diagnosis, Differential","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003951","descriptor_name":"Diagnostic Errors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013964","descriptor_name":"Thyroid Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D013964","descriptor_name":"Thyroid Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D013964","descriptor_name":"Thyroid Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D015588","descriptor_name":"Observer Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018249","descriptor_name":"Adenoma, Oxyphilic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D018249","descriptor_name":"Adenoma, Oxyphilic","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D018249","descriptor_name":"Adenoma, Oxyphilic","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D018263","descriptor_name":"Adenocarcinoma, Follicular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/dc.21363","doi":"https://doi.org/10.1002/dc.21363","is_oa":false,"landing_page_url":"https://doi.org/10.1002/dc.21363","pdf_url":null,"source":{"id":"https://openalex.org/S23314063","display_name":"Diagnostic Cytopathology","issn_l":"1097-0339","issn":["1097-0339","8755-1039"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diagnostic Cytopathology","raw_type":"journal-article"},{"id":"pmid:21416635","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21416635","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diagnostic cytopathology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W120472884","https://openalex.org/W1795008313","https://openalex.org/W1926228846","https://openalex.org/W1932946942","https://openalex.org/W1936715766","https://openalex.org/W1965536769","https://openalex.org/W1982678950","https://openalex.org/W1983882607","https://openalex.org/W1985982375","https://openalex.org/W1989243569","https://openalex.org/W1990350358","https://openalex.org/W1992148981","https://openalex.org/W1992378979","https://openalex.org/W2002718758","https://openalex.org/W2008126961","https://openalex.org/W2009925064","https://openalex.org/W2011562398","https://openalex.org/W2013868768","https://openalex.org/W2029915040","https://openalex.org/W2035453768","https://openalex.org/W2038680452","https://openalex.org/W2041444867","https://openalex.org/W2044451855","https://openalex.org/W2046062300","https://openalex.org/W2050107327","https://openalex.org/W2053380842","https://openalex.org/W2055636465","https://openalex.org/W2063211982","https://openalex.org/W2070689236","https://openalex.org/W2078063970","https://openalex.org/W2084827347","https://openalex.org/W2090842981","https://openalex.org/W2116413869","https://openalex.org/W2159995777","https://openalex.org/W2168402896","https://openalex.org/W2169588225","https://openalex.org/W2406827122","https://openalex.org/W2413596821","https://openalex.org/W2415224864","https://openalex.org/W3025146595","https://openalex.org/W4243545562"],"related_works":["https://openalex.org/W2044451855","https://openalex.org/W3030413330","https://openalex.org/W2258031711","https://openalex.org/W1974077717","https://openalex.org/W2043534129","https://openalex.org/W2158792987","https://openalex.org/W7004883673","https://openalex.org/W2044417031","https://openalex.org/W2077339940","https://openalex.org/W7143786709"],"abstract_inverted_index":{"The":[0,15,104,158],"difficulty":[1],"in":[2,31,111,165,178,183],"correctly":[3],"identifying":[4],"follicular":[5,66,188,195],"lesions/neoplasms":[6],"(FN)":[7,198],"of":[8,24,34,39,60,68,93,106,180,187,211],"thyroid":[9],"is":[10,173],"a":[11,45,85,102,208],"well":[12],"recognized":[13],"fact.":[14],"present":[16],"study":[17,21],"was":[18,116,161,190],"undertaken":[19],"to":[20,156,192,219],"the":[22,32],"degree":[23],"interobserver":[25,169,221],"variability":[26,222],"among":[27,171,202],"cytopathologists":[28],"and":[29,65,74,108,128,163,223],"histopathologists":[30],"diagnosis":[33,47,160,179,186,210],"these":[35,80],"lesions.":[36],"A":[37],"total":[38],"74":[40],"cases":[41,81,92,120,133,141,185,206],"were":[42,82,98,121,134,142],"chosen":[43],"with":[44,88,207,217],"cytological":[46,209],"varying":[48],"from":[49,154],"FN":[50,127,212],"(43":[51],"cases),":[52,57],"h\u00fcrthle":[53],"cell":[54],"neoplasm":[55,58],"(18":[56],"suspicious":[59],"papillary":[61,69],"carcinoma":[62,70],"(7":[63],"cases)":[64,73],"variant":[67],"(FVPTC)":[71],"(4":[72],"neoplasm,":[75],"NOS":[76],"(2":[77],"cases).":[78],"All":[79],"reviewed":[83,100,109,130,145,162,215,224],"by":[84,101],"cytopathologist":[86],"along":[87,216],"surgical":[89],"follow-up.":[90],"In":[91],"cytohistological":[94],"discordance,":[95],"histopathological":[96],"diagnoses":[97],"also":[99],"histopathologist.":[103],"accuracy":[105],"initial":[107,124],"cytology":[110,125],"predicting":[112],"neoplastic":[113,150],"histological":[114,151],"outcome":[115,152],"100%;":[117],"however":[118,138],"15":[119],"over-diagnosed":[122,143],"on":[123,129,144],"as":[126,136,182,229],"cytology,":[131,146],"8/15":[132],"under-diagnosed":[135],"non-neoplastic;":[137],"still":[139],"seven":[140],"thereby":[147],"specificity":[148],"for":[149],"ranging":[153],"50":[155],"68%.":[157],"histopathology":[159,218,225],"changed":[164,191],"six":[166],"cases;":[167],"therefore":[168],"agreement":[170],"histopathologist":[172],"92%":[174],"which":[175],"reduces":[176],"further":[177],"FVPTC,":[181],"two":[184],"adenoma":[189],"FVPTC.":[193],"Neoplastic":[194],"patterned":[196],"lesions":[197],"pose":[199],"diagnostic":[200],"difficulties":[201],"pathologists.":[203],"So,":[204],"all":[205],"should":[213,226],"be":[214,227],"minimize":[220],"considered":[228],"\"gold":[230],"standard\".":[231]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}