{"id":"https://openalex.org/W2097113013","doi":"https://doi.org/10.1189/jlb.0811394","title":"Monocyte maturation, HIV susceptibility, and transmigration across the blood brain barrier are critical in HIV neuropathogenesis","display_name":"Monocyte maturation, HIV susceptibility, and transmigration across the blood brain barrier are critical in HIV neuropathogenesis","publication_year":2012,"publication_date":"2012-01-06","ids":{"openalex":"https://openalex.org/W2097113013","doi":"https://doi.org/10.1189/jlb.0811394","mag":"2097113013","pmid":"https://pubmed.ncbi.nlm.nih.gov/22227964","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3289493"},"language":"en","primary_location":{"id":"doi:10.1189/jlb.0811394","doi":"https://doi.org/10.1189/jlb.0811394","is_oa":true,"landing_page_url":"https://doi.org/10.1189/jlb.0811394","pdf_url":"https://academic.oup.com/jleukbio/article-pdf/91/3/401/48407406/jlb0401.pdf","source":{"id":"https://openalex.org/S199011235","display_name":"Journal of Leukocyte Biology","issn_l":"0741-5400","issn":["0741-5400","1938-3673"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Leukocyte Biology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/jleukbio/article-pdf/91/3/401/48407406/jlb0401.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033035155","display_name":"Dionna W. Williams","orcid":"https://orcid.org/0000-0001-5029-2628","observed_orcids":["https://orcid.org/0000-0001-5029-2628"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dionna W Williams","raw_affiliation_strings":["Department of Pathology, The Albert Einstein College of Medicine , Bronx, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, The Albert Einstein College of Medicine , Bronx, New York, USA","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103580330","display_name":"Eliseo A. Eugenin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eliseo A Eugenin","raw_affiliation_strings":["Department of Pathology, The Albert Einstein College of Medicine , Bronx, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, The Albert Einstein College of Medicine , Bronx, New York, USA","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078205323","display_name":"Tina M. Calderon","orcid":"https://orcid.org/0000-0001-9929-7120","observed_orcids":["https://orcid.org/0000-0001-9929-7120"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tina M Calderon","raw_affiliation_strings":["Department of Pathology, The Albert Einstein College of Medicine , Bronx, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, The Albert Einstein College of Medicine , Bronx, New York, USA","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057650635","display_name":"Joan W. Berman","orcid":"https://orcid.org/0000-0003-0635-4072","observed_orcids":["https://orcid.org/0000-0003-0635-4072"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Joan W Berman","raw_affiliation_strings":["Department of Microbiology and Immunology, The Albert Einstein College of Medicine , Bronx, New York, USA","Department of Pathology, The Albert Einstein College of Medicine , Bronx, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, The Albert Einstein College of Medicine , Bronx, New York, USA","institution_ids":["https://openalex.org/I129975664"]},{"raw_affiliation_string":"Department of Pathology, The Albert Einstein College of Medicine , Bronx, New York, USA","institution_ids":["https://openalex.org/I129975664"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5057650635"],"corresponding_institution_ids":["https://openalex.org/I129975664"],"apc_list":{"value":3800,"currency":"USD","value_usd":3800},"apc_paid":null,"fwci":2.4577,"has_fulltext":true,"cited_by_count":217,"citation_normalized_percentile":{"value":0.91156463,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"91","issue":"3","first_page":"401","last_page":"415"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9574999809265137,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9574999809265137,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.033799998462200165,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hiv","display_name":"HIV","score":0.6430000066757202},{"id":"https://openalex.org/keywords/hiv-associated-neurocognitive-disorders","display_name":"HIV-associated neurocognitive disorders","score":0.8820000290870667},{"id":"https://openalex.org/keywords/monocyte-maturation","display_name":"monocyte maturation","score":0.8100000023841858},{"id":"https://openalex.org/keywords/cd14-cd16-monocytes","display_name":"CD14+CD16+ monocytes","score":0.9300000071525574},{"id":"https://openalex.org/keywords/monocyte-transmigration","display_name":"monocyte transmigration","score":0.8600000143051147},{"id":"https://openalex.org/keywords/blood-brain-barrier","display_name":"blood-brain barrier","score":0.9779999852180481},{"id":"https://openalex.org/keywords/neuroinflammation","display_name":"neuroinflammation","score":0.8040000200271606},{"id":"https://openalex.org/keywords/monocyte-differentiation","display_name":"monocyte differentiation","score":0.6449999809265137},{"id":"https://openalex.org/keywords/monocyte-subpopulations","display_name":"monocyte subpopulations","score":0.6380000114440918},{"id":"https://openalex.org/keywords/chemotaxis","display_name":"chemotaxis","score":0.597000002861023},{"id":"https://openalex.org/keywords/monocyte-endothelial-interaction","display_name":"monocyte-endothelial interaction","score":0.7229999899864197},{"id":"https://openalex.org/keywords/hiv-neuropathogenesis","display_name":"HIV neuropathogenesis","score":0.4950000047683716},{"id":"https://openalex.org/keywords/cognitive-impairment","display_name":"cognitive impairment","score":0.46399998664855957}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7685093283653259},{"id":"https://openalex.org/C2781184567","wikidata":"https://www.wikidata.org/wiki/Q107244","display_name":"Monocyte","level":2,"score":0.7152583003044128},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6724700927734375},{"id":"https://openalex.org/C2778513237","wikidata":"https://www.wikidata.org/wiki/Q419553","display_name":"CD14","level":3,"score":0.6504343152046204},{"id":"https://openalex.org/C87753298","wikidata":"https://www.wikidata.org/wiki/Q17157137","display_name":"Neuroinflammation","level":3,"score":0.6245726346969604},{"id":"https://openalex.org/C106358424","wikidata":"https://www.wikidata.org/wiki/Q1662346","display_name":"Infectivity","level":3,"score":0.612438440322876},{"id":"https://openalex.org/C2781462264","wikidata":"https://www.wikidata.org/wiki/Q78482053","display_name":"CD16","level":5,"score":0.5631191730499268},{"id":"https://openalex.org/C2779830541","wikidata":"https://www.wikidata.org/wiki/Q1622829","display_name":"Microglia","level":3,"score":0.5597305297851562},{"id":"https://openalex.org/C2778402981","wikidata":"https://www.wikidata.org/wiki/Q221694","display_name":"Blood\u2013brain barrier","level":3,"score":0.5241159200668335},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.4993324279785156},{"id":"https://openalex.org/C13373296","wikidata":"https://www.wikidata.org/wiki/Q421866","display_name":"Chemokine","level":3,"score":0.49355757236480713},{"id":"https://openalex.org/C196822366","wikidata":"https://www.wikidata.org/wiki/Q270524","display_name":"Parenchyma","level":2,"score":0.4758205711841583},{"id":"https://openalex.org/C54166955","wikidata":"https://www.wikidata.org/wiki/Q658145","display_name":"Chemotaxis","level":3,"score":0.4646349251270294},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4152376055717468},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.38139575719833374},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.31326282024383545},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.2714000940322876},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.16476169228553772},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.15942546725273132},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.08126261830329895},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0708569586277008},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.062453001737594604},{"id":"https://openalex.org/C114684123","wikidata":"https://www.wikidata.org/wiki/Q419458","display_name":"CD3","level":4,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001812","descriptor_name":"Blood-Brain Barrier","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001812","descriptor_name":"Blood-Brain Barrier","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D003072","descriptor_name":"Cognition Disorders","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008251","descriptor_name":"Macaca","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D009000","descriptor_name":"Monocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009000","descriptor_name":"Monocytes","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D016130","descriptor_name":"Immunophenotyping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018792","descriptor_name":"Encephalitis, Viral","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D057705","descriptor_name":"Transendothelial and Transepithelial Migration","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1189/jlb.0811394","doi":"https://doi.org/10.1189/jlb.0811394","is_oa":true,"landing_page_url":"https://doi.org/10.1189/jlb.0811394","pdf_url":"https://academic.oup.com/jleukbio/article-pdf/91/3/401/48407406/jlb0401.pdf","source":{"id":"https://openalex.org/S199011235","display_name":"Journal of Leukocyte Biology","issn_l":"0741-5400","issn":["0741-5400","1938-3673"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Leukocyte Biology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2581770","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3289493","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3289493","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3289493","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Leukoc Biol","raw_type":"Text"},{"id":"pmid:22227964","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22227964","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of leukocyte biology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1189/jlb.0811394","doi":"https://doi.org/10.1189/jlb.0811394","is_oa":true,"landing_page_url":"https://doi.org/10.1189/jlb.0811394","pdf_url":"https://academic.oup.com/jleukbio/article-pdf/91/3/401/48407406/jlb0401.pdf","source":{"id":"https://openalex.org/S199011235","display_name":"Journal of Leukocyte Biology","issn_l":"0741-5400","issn":["0741-5400","1938-3673"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Leukocyte Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1746084509","display_name":"Astrocyte connexin43 containing channels amplify CNS dysfunction in NeuroAIDS","funder_award_id":"R01MH096625","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G245833252","display_name":"The role of gap junction channels in NeuroAIDS","funder_award_id":"K01MH076679","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G3301967420","display_name":"Role of cellular prion protein in the pathogenesis of NeuroAIDS","funder_award_id":"R01MH090958","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G4011844279","display_name":"Center for AIDS Research (CFAR)","funder_award_id":"P30AI051519","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G5663993750","display_name":"Mechanisms of HAD:Role of CCL2 BBB & HIV Infection","funder_award_id":"R01MH075679","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G8637736929","display_name":"Dopamine alters CNS migration of uninfected and HIV infected leukocytes to SDF-1","funder_award_id":"R01DA025567","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"},{"id":"https://openalex.org/G8943345842","display_name":"Geographic Medicine and Emerging Infections","funder_award_id":"T32AI070117","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G9000102541","display_name":null,"funder_award_id":"AI-051519","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337347","display_name":"National Institute on Drug Abuse","ror":"https://ror.org/00fq5cm18"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2097113013.pdf","grobid_xml":"https://content.openalex.org/works/W2097113013.grobid-xml"},"referenced_works_count":212,"referenced_works":["https://openalex.org/W89214381","https://openalex.org/W91305346","https://openalex.org/W123631083","https://openalex.org/W1523754932","https://openalex.org/W1526496165","https://openalex.org/W1527149701","https://openalex.org/W1530364137","https://openalex.org/W1535701012","https://openalex.org/W1557119871","https://openalex.org/W1571153387","https://openalex.org/W1600863966","https://openalex.org/W1605039210","https://openalex.org/W1849900443","https://openalex.org/W1878746864","https://openalex.org/W1942368010","https://openalex.org/W1964377755","https://openalex.org/W1966064265","https://openalex.org/W1969841262","https://openalex.org/W1970802765","https://openalex.org/W1973798740","https://openalex.org/W1974281422","https://openalex.org/W1974749956","https://openalex.org/W1975305176","https://openalex.org/W1975447710","https://openalex.org/W1976434061","https://openalex.org/W1978155055","https://openalex.org/W1978665463","https://openalex.org/W1979857580","https://openalex.org/W1983521453","https://openalex.org/W1984378291","https://openalex.org/W1988165884","https://openalex.org/W1990030335","https://openalex.org/W1991556620","https://openalex.org/W1991749307","https://openalex.org/W1993250333","https://openalex.org/W1993382722","https://openalex.org/W1995227965","https://openalex.org/W1999478240","https://openalex.org/W1999730476","https://openalex.org/W2000137099","https://openalex.org/W2000441131","https://openalex.org/W2000878624","https://openalex.org/W2001088431","https://openalex.org/W2001666173","https://openalex.org/W2003205128","https://openalex.org/W2004070471","https://openalex.org/W2004207884","https://openalex.org/W2005385321","https://openalex.org/W2005519900","https://openalex.org/W2007087804","https://openalex.org/W2007670233","https://openalex.org/W2010072143","https://openalex.org/W2010501182","https://openalex.org/W2013663529","https://openalex.org/W2013805935","https://openalex.org/W2015141049","https://openalex.org/W2015541518","https://openalex.org/W2016191021","https://openalex.org/W2017605183","https://openalex.org/W2019248029","https://openalex.org/W2019602756","https://openalex.org/W2020673372","https://openalex.org/W2021195622","https://openalex.org/W2021338883","https://openalex.org/W2021712645","https://openalex.org/W2022450093","https://openalex.org/W2022482220","https://openalex.org/W2023089171","https://openalex.org/W2023368657","https://openalex.org/W2023756943","https://openalex.org/W2024442062","https://openalex.org/W2024572594","https://openalex.org/W2025468276","https://openalex.org/W2025960989","https://openalex.org/W2026125174","https://openalex.org/W2026359714","https://openalex.org/W2026444780","https://openalex.org/W2026578487","https://openalex.org/W2027580727","https://openalex.org/W2028850032","https://openalex.org/W2033784609","https://openalex.org/W2035316009","https://openalex.org/W2035809865","https://openalex.org/W2038295450","https://openalex.org/W2038418972","https://openalex.org/W2038905719","https://openalex.org/W2039746759","https://openalex.org/W2041925142","https://openalex.org/W2042482120","https://openalex.org/W2042603556","https://openalex.org/W2042982138","https://openalex.org/W2044455774","https://openalex.org/W2046532390","https://openalex.org/W2047044941","https://openalex.org/W2047903168","https://openalex.org/W2048198814","https://openalex.org/W2049578584","https://openalex.org/W2049714146","https://openalex.org/W2049791475","https://openalex.org/W2049866297","https://openalex.org/W2051040572","https://openalex.org/W2051122335","https://openalex.org/W2052769426","https://openalex.org/W2052955118","https://openalex.org/W2053963733","https://openalex.org/W2054542448","https://openalex.org/W2055783050","https://openalex.org/W2056169141","https://openalex.org/W2056402708","https://openalex.org/W2057797562","https://openalex.org/W2058403652","https://openalex.org/W2059552988","https://openalex.org/W2062296742","https://openalex.org/W2063785040","https://openalex.org/W2064760135","https://openalex.org/W2065170135","https://openalex.org/W2068084209","https://openalex.org/W2074466423","https://openalex.org/W2075319928","https://openalex.org/W2077274120","https://openalex.org/W2077330157","https://openalex.org/W2078701896","https://openalex.org/W2079054746","https://openalex.org/W2080514032","https://openalex.org/W2082314789","https://openalex.org/W2083172100","https://openalex.org/W2085296463","https://openalex.org/W2086419987","https://openalex.org/W2086636233","https://openalex.org/W2088746151","https://openalex.org/W2089951882","https://openalex.org/W2090458882","https://openalex.org/W2090532515","https://openalex.org/W2090630729","https://openalex.org/W2091061672","https://openalex.org/W2094393090","https://openalex.org/W2094586624","https://openalex.org/W2096030919","https://openalex.org/W2096179876","https://openalex.org/W2097433834","https://openalex.org/W2098345971","https://openalex.org/W2099982660","https://openalex.org/W2102186747","https://openalex.org/W2102461299","https://openalex.org/W2103348038","https://openalex.org/W2104741590","https://openalex.org/W2105594104","https://openalex.org/W2105971784","https://openalex.org/W2109169003","https://openalex.org/W2109350709","https://openalex.org/W2111315060","https://openalex.org/W2111569391","https://openalex.org/W2112423179","https://openalex.org/W2113047516","https://openalex.org/W2113345760","https://openalex.org/W2113839963","https://openalex.org/W2114224767","https://openalex.org/W2115056738","https://openalex.org/W2115091858","https://openalex.org/W2115118763","https://openalex.org/W2115235607","https://openalex.org/W2115316421","https://openalex.org/W2116444325","https://openalex.org/W2116862225","https://openalex.org/W2117538259","https://openalex.org/W2120862613","https://openalex.org/W2121511328","https://openalex.org/W2121716202","https://openalex.org/W2127156420","https://openalex.org/W2130599091","https://openalex.org/W2136973280","https://openalex.org/W2137798077","https://openalex.org/W2138902434","https://openalex.org/W2140150768","https://openalex.org/W2141050083","https://openalex.org/W2141400607","https://openalex.org/W2141826840","https://openalex.org/W2144882745","https://openalex.org/W2145464880","https://openalex.org/W2147971828","https://openalex.org/W2149352351","https://openalex.org/W2149443760","https://openalex.org/W2152353759","https://openalex.org/W2152364824","https://openalex.org/W2152376324","https://openalex.org/W2152669164","https://openalex.org/W2153932008","https://openalex.org/W2154733328","https://openalex.org/W2155176167","https://openalex.org/W2155226726","https://openalex.org/W2156784778","https://openalex.org/W2157153819","https://openalex.org/W2157418548","https://openalex.org/W2158287015","https://openalex.org/W2158550197","https://openalex.org/W2158926036","https://openalex.org/W2163237181","https://openalex.org/W2164663536","https://openalex.org/W2165052021","https://openalex.org/W2165627434","https://openalex.org/W2166833739","https://openalex.org/W2167732879","https://openalex.org/W2167906381","https://openalex.org/W2168115703","https://openalex.org/W2319657764","https://openalex.org/W2339219218","https://openalex.org/W2345609573","https://openalex.org/W2431053956","https://openalex.org/W4235285967","https://openalex.org/W4313348020","https://openalex.org/W4322387793","https://openalex.org/W6675756949"],"related_works":["https://openalex.org/W2111518980","https://openalex.org/W2010072143","https://openalex.org/W1246470473","https://openalex.org/W7155000994","https://openalex.org/W7098869474","https://openalex.org/W2012700090","https://openalex.org/W2103097492","https://openalex.org/W7097043220","https://openalex.org/W3196492823","https://openalex.org/W2765432785"],"abstract_inverted_index":{"HIV":[0,28,87,161,182,212],"continues":[1],"to":[2,71,86,98,192],"be":[3],"a":[4,39,44,77],"global":[5],"health":[6],"crisis":[7],"with":[8,62,117],"more":[9,84],"than":[10],"34":[11],"million":[12],"people":[13],"infected":[14,48,61],"worldwide":[15],"(UNAIDS:":[16],"Report":[17],"on":[18,107,120,204],"the":[19,30,55,90,93,103,108,123,129,139,153,155,164,171,177,187,193,215,223,226],"Global":[20],"AIDS":[21],"Epidemic":[22],"2010,":[23],"Geneva,":[24],"World":[25],"Health":[26],"Organization).":[27],"enters":[29],"CNS":[31,94,188],"within":[32],"2":[33],"weeks":[34],"of":[35,41,47,57,59,66,76,122,150,163,179,195,206],"infection":[36,162],"and":[37,114,141,184,214],"establishes":[38],"spectrum":[40],"HAND":[42,67],"in":[43,96,112,198],"large":[45],"percentage":[46],"individuals.":[49,200],"These":[50],"neurologic":[51],"deficits":[52],"greatly":[53],"impact":[54],"quality":[56],"life":[58],"those":[60,118],"HIV.":[63],"The":[64],"establishment":[65,194],"is":[68,83,133,147],"largely":[69],"attributed":[70],"monocyte":[72,80,168,180,207],"transmigration,":[73],"particularly":[74],"that":[75,190,217],"mature":[78],"CD14(+)CD16(+)":[79],"population,":[81],"which":[82],"susceptible":[85],"infection,":[88],"across":[89,128,222],"BBB":[91,124,224],"into":[92,138,152,170,186,225],"parenchyma":[95,189],"response":[97],"chemotactic":[99,157],"signals.":[100],"To":[101],"enter":[102],"CNS,":[104,154],"junctional":[105],"proteins":[106],"monocytes":[109,151],"must":[110],"participate":[111],"homo-":[113],"heterotypic":[115],"interactions":[116],"present":[119,159],"BMVECs":[121],"as":[125],"they":[126],"transmigrate":[127],"barrier.":[130],"This":[131,173],"transmigration":[132,169,185,221],"responsible":[134],"for":[135],"bringing":[136],"virus":[137],"brain":[140,165],"establishing":[142],"chronic":[143],"neuroinflammation.":[144],"While":[145],"there":[146],"baseline":[148],"trafficking":[149],"increased":[156,220],"signals":[158],"during":[160],"promote":[166,218],"exuberant":[167],"CNS.":[172,227],"review":[174],"will":[175,202],"discuss":[176],"mechanisms":[178,216],"differentiation/maturation,":[181],"infectivity,":[183,213],"contribute":[191],"cognitive":[196],"impairment":[197],"HIV-infected":[199],"It":[201],"focus":[203],"markers":[205],"subpopulations,":[208],"how":[209],"differentiation/maturation":[210],"alters":[211],"their":[219]},"counts_by_year":[{"year":2026,"cited_by_count":11},{"year":2025,"cited_by_count":11},{"year":2024,"cited_by_count":17},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":17},{"year":2021,"cited_by_count":14},{"year":2020,"cited_by_count":11},{"year":2019,"cited_by_count":13},{"year":2018,"cited_by_count":14},{"year":2017,"cited_by_count":13},{"year":2016,"cited_by_count":15},{"year":2015,"cited_by_count":17},{"year":2014,"cited_by_count":30},{"year":2013,"cited_by_count":16},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}
