{"id":"https://openalex.org/W2096862988","doi":"https://doi.org/10.1111/j.1467-8721.2007.00468.x","title":"Sleep and Immunity","display_name":"Sleep and Immunity","publication_year":2007,"publication_date":"2007-02-01","ids":{"openalex":"https://openalex.org/W2096862988","doi":"https://doi.org/10.1111/j.1467-8721.2007.00468.x","mag":"2096862988"},"language":"en","primary_location":{"id":"doi:10.1111/j.1467-8721.2007.00468.x","doi":"https://doi.org/10.1111/j.1467-8721.2007.00468.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1467-8721.2007.00468.x","pdf_url":null,"source":{"id":"https://openalex.org/S114020440","display_name":"Current Directions in Psychological Science","issn_l":"0963-7214","issn":["0963-7214","1467-8721"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","erih-plus","jufo-2","ki-jl-1","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Directions in Psychological Science","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070565569","display_name":"Sarosh J. Motivala","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sarosh J. Motivala","raw_affiliation_strings":["Cousins Center for Psychoneuroimmunology, University of California, Los Angeles"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cousins Center for Psychoneuroimmunology, University of California, Los Angeles","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005936736","display_name":"Michael R. Irwin","orcid":"https://orcid.org/0000-0002-1502-8431","observed_orcids":["https://orcid.org/0000-0002-1502-8431"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael R. Irwin","raw_affiliation_strings":["Cousins Center for Psychoneuroimmunology, University of California, Los Angeles"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cousins Center for Psychoneuroimmunology, University of California, Los Angeles","institution_ids":["https://openalex.org/I161318765"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5070565569"],"corresponding_institution_ids":["https://openalex.org/I161318765"],"apc_list":{"value":3900,"currency":"USD","value_usd":3900},"apc_paid":null,"fwci":0.5853,"has_fulltext":false,"cited_by_count":53,"citation_normalized_percentile":{"value":0.65357911,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"16","issue":"1","first_page":"21","last_page":"25"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":0.9810000061988831,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":0.9810000061988831,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10316","display_name":"Sleep and related disorders","score":0.014000000432133675,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sleep","display_name":"sleep","score":0.984000027179718},{"id":"https://openalex.org/keywords/immunity","display_name":"immunity","score":0.8320000171661377},{"id":"https://openalex.org/keywords/cytokines","display_name":"cytokines","score":0.8169999718666077},{"id":"https://openalex.org/keywords/brain-immune-communication","display_name":"brain-immune communication","score":0.6710000038146973},{"id":"https://openalex.org/keywords/sleep-regulation","display_name":"sleep regulation","score":0.8050000071525574},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.9779999852180481},{"id":"https://openalex.org/keywords/interleukin-1","display_name":"interleukin-1","score":0.9990000128746033},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":0.9990000128746033},{"id":"https://openalex.org/keywords/chronic-disease","display_name":"chronic disease","score":0.7350000143051147}],"concepts":[{"id":"https://openalex.org/C2775841894","wikidata":"https://www.wikidata.org/wiki/Q4683692","display_name":"Sleep (system call)","level":2,"score":0.793226420879364},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.7037109136581421},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.6145591735839844},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5746766328811646},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5543211102485657},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.5014393329620361},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.339889258146286},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.251198410987854},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1111/j.1467-8721.2007.00468.x","doi":"https://doi.org/10.1111/j.1467-8721.2007.00468.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1467-8721.2007.00468.x","pdf_url":null,"source":{"id":"https://openalex.org/S114020440","display_name":"Current Directions in Psychological Science","issn_l":"0963-7214","issn":["0963-7214","1467-8721"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","erih-plus","jufo-2","ki-jl-1","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Directions in Psychological Science","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W1568315239","https://openalex.org/W1569179190","https://openalex.org/W1592968073","https://openalex.org/W1719035976","https://openalex.org/W1880976932","https://openalex.org/W1972748441","https://openalex.org/W1986282550","https://openalex.org/W2012968633","https://openalex.org/W2014593621","https://openalex.org/W2021144163","https://openalex.org/W2024392891","https://openalex.org/W2027223222","https://openalex.org/W2030421130","https://openalex.org/W2047445016","https://openalex.org/W2049445917","https://openalex.org/W2056930167","https://openalex.org/W2062175236","https://openalex.org/W2066963386","https://openalex.org/W2071697888","https://openalex.org/W2075961471","https://openalex.org/W2106715395","https://openalex.org/W2107420413","https://openalex.org/W2126439770"],"related_works":["https://openalex.org/W2232365314","https://openalex.org/W1990175188","https://openalex.org/W1485647838","https://openalex.org/W2875527","https://openalex.org/W2870593585","https://openalex.org/W7154016364","https://openalex.org/W4402681480","https://openalex.org/W4212989482","https://openalex.org/W2070700200","https://openalex.org/W117106693"],"abstract_inverted_index":{"The":[0],"functions":[1],"of":[2,110,119],"sleep":[3,24,58,63,106,129],"are":[4,7,38,83,113],"enigmatic":[5],"but":[6],"beginning":[8],"to":[9,17],"be":[10,18],"delineated.":[11],"Sleep":[12],"has":[13],"been":[14],"long":[15],"thought":[16],"important":[19,84],"for":[20,36],"health,":[21],"and":[22,59,61,65,75,90,99,122],"poor":[23,128],"is":[25],"prospectively":[26],"associated":[27,115],"with":[28,116,130],"worsened":[29],"health":[30,60,131],"outcomes.":[31,132],"Yet":[32],"the":[33,48,55],"mechanisms":[34],"accounting":[35],"this":[37,43],"only":[39],"partially":[40],"understood.":[41],"In":[42],"review,":[44],"we":[45],"suggest":[46],"that":[47,62],"immune":[49],"system":[50,88],"plays":[51],"a":[52,102,117,125],"role":[53,104],"in":[54,72,85,105],"relationship":[56],"between":[57],"processes":[64],"immunity":[66],"show":[67],"bidirectional":[68],"interactions,":[69],"as":[70,94],"evidenced":[71],"both":[73],"animal":[74],"human":[76],"studies.":[77],"Immunological":[78],"signaling":[79],"molecules,":[80],"termed":[81],"cytokines,":[82],"coordinating":[86],"brain\u2013immune":[87],"communication,":[89],"particular":[91],"cytokines":[92,112],"such":[93],"tumor":[95],"necrosis":[96],"factor,":[97],"interleukin-1,":[98],"interleukin-6":[100],"play":[101],"crucial":[103],"regulation.":[107],"Elevated":[108],"levels":[109],"these":[111],"also":[114],"number":[118],"chronic":[120],"diseases":[121],"may":[123],"provide":[124],"pathway":[126],"linking":[127]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}