{"id":"https://openalex.org/W2096664751","doi":"https://doi.org/10.1128/jb.00761-06","title":"Interaction between Coat Morphogenetic Proteins SafA and SpoVID","display_name":"Interaction between Coat Morphogenetic Proteins SafA and SpoVID","publication_year":2006,"publication_date":"2006-11-02","ids":{"openalex":"https://openalex.org/W2096664751","doi":"https://doi.org/10.1128/jb.00761-06","mag":"2096664751","pmid":"https://pubmed.ncbi.nlm.nih.gov/16950916","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1636312"},"language":"en","primary_location":{"id":"doi:10.1128/jb.00761-06","doi":"https://doi.org/10.1128/jb.00761-06","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jb.00761-06","pdf_url":null,"source":{"id":"https://openalex.org/S133274750","display_name":"Journal of Bacteriology","issn_l":"0021-9193","issn":["0021-9193","1067-8832","1098-5530"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Bacteriology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1636312","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Teresa Costa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I83558840","display_name":"Universidade Nova de Lisboa","ror":"https://ror.org/02xankh89","country_code":"PT","type":"education","lineage":["https://openalex.org/I83558840"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Teresa Costa","raw_affiliation_strings":["Instituto de Tecnologia Qui\u0301mica e Biolo\u0301gica, Universidade Nova de Lisboa, Avenida da Repu\u0301blica, EAN, 2781-157 Oeiras, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto de Tecnologia Qui\u0301mica e Biolo\u0301gica, Universidade Nova de Lisboa, Avenida da Repu\u0301blica, EAN, 2781-157 Oeiras, Portugal","institution_ids":["https://openalex.org/I83558840"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000509930","display_name":"Anabela L. Isidro","orcid":"https://orcid.org/0000-0001-6561-9814","observed_orcids":["https://orcid.org/0000-0001-6561-9814"]},"institutions":[{"id":"https://openalex.org/I83558840","display_name":"Universidade Nova de Lisboa","ror":"https://ror.org/02xankh89","country_code":"PT","type":"education","lineage":["https://openalex.org/I83558840"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Anabela L. Isidro","raw_affiliation_strings":["Instituto de Tecnologia Qui\u0301mica e Biolo\u0301gica, Universidade Nova de Lisboa, Avenida da Repu\u0301blica, EAN, 2781-157 Oeiras, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto de Tecnologia Qui\u0301mica e Biolo\u0301gica, Universidade Nova de Lisboa, Avenida da Repu\u0301blica, EAN, 2781-157 Oeiras, Portugal","institution_ids":["https://openalex.org/I83558840"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005192610","display_name":"Charles P. Moran","orcid":"https://orcid.org/0000-0002-5795-9090","observed_orcids":["https://orcid.org/0000-0002-5795-9090"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles P. Moran","raw_affiliation_strings":["Emory University School of Medicine, Department of Microbiology and Immunology, 3010 Rollins Research Center, Atlanta, Georgia 30322"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Emory University School of Medicine, Department of Microbiology and Immunology, 3010 Rollins Research Center, Atlanta, Georgia 30322","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090467258","display_name":"Adriano O. Henriques","orcid":"https://orcid.org/0000-0003-4292-4802","observed_orcids":["https://orcid.org/0000-0003-4292-4802"]},"institutions":[{"id":"https://openalex.org/I83558840","display_name":"Universidade Nova de Lisboa","ror":"https://ror.org/02xankh89","country_code":"PT","type":"education","lineage":["https://openalex.org/I83558840"]}],"countries":["PT"],"is_corresponding":true,"raw_author_name":"Adriano O. Henriques","raw_affiliation_strings":["Instituto de Tecnologia Qui\u0301mica e Biolo\u0301gica, Universidade Nova de Lisboa, Avenida da Repu\u0301blica, EAN, 2781-157 Oeiras, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto de Tecnologia Qui\u0301mica e Biolo\u0301gica, Universidade Nova de Lisboa, Avenida da Repu\u0301blica, EAN, 2781-157 Oeiras, Portugal","institution_ids":["https://openalex.org/I83558840"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5090467258"],"corresponding_institution_ids":["https://openalex.org/I83558840"],"apc_list":null,"apc_paid":null,"fwci":1.0787,"has_fulltext":false,"cited_by_count":48,"citation_normalized_percentile":{"value":0.75482122,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"188","issue":"22","first_page":"7731","last_page":"7741"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11515","display_name":"Bacillus and Francisella bacterial research","score":0.003100000089034438,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13326","display_name":"Biochemical and Structural Characterization","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/safa","display_name":"SAFA","score":0.8679999709129333},{"id":"https://openalex.org/keywords/bacillus-subtilis","display_name":"Bacillus subtilis","score":0.9639999866485596},{"id":"https://openalex.org/keywords/protein-protein-interaction","display_name":"protein-protein interaction","score":0.8989999890327454},{"id":"https://openalex.org/keywords/lysm-domain","display_name":"LysM domain","score":0.984000027179718},{"id":"https://openalex.org/keywords/peptidoglycan-binding","display_name":"peptidoglycan binding","score":0.9580000042915344},{"id":"https://openalex.org/keywords/lysozyme-susceptibility","display_name":"lysozyme susceptibility","score":0.7879999876022339},{"id":"https://openalex.org/keywords/protein-localization","display_name":"protein localization","score":0.5139999985694885}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9124593734741211},{"id":"https://openalex.org/C2777272437","wikidata":"https://www.wikidata.org/wiki/Q131238","display_name":"Bacillus subtilis","level":3,"score":0.6466591358184814},{"id":"https://openalex.org/C2776634448","wikidata":"https://www.wikidata.org/wiki/Q206920","display_name":"Peptidoglycan","level":3,"score":0.5144386887550354},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4635791778564453},{"id":"https://openalex.org/C2776966407","wikidata":"https://www.wikidata.org/wiki/Q24779410","display_name":"Lysozyme","level":2,"score":0.43383505940437317},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4017769694328308},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.13837137818336487},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.11901676654815674}],"mesh":[{"descriptor_ui":"D001412","descriptor_name":"Bacillus subtilis","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D001412","descriptor_name":"Bacillus subtilis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009113","descriptor_name":"Muramidase","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013171","descriptor_name":"Spores, Bacterial","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D013171","descriptor_name":"Spores, Bacterial","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D020816","descriptor_name":"Amino Acid Motifs","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1128/jb.00761-06","doi":"https://doi.org/10.1128/jb.00761-06","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jb.00761-06","pdf_url":null,"source":{"id":"https://openalex.org/S133274750","display_name":"Journal of Bacteriology","issn_l":"0021-9193","issn":["0021-9193","1067-8832","1098-5530"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Bacteriology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1636312","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1636312","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Bacteriol","raw_type":"Text"},{"id":"pmid:16950916","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16950916","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of bacteriology","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.691.1549","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.691.1549","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636312/pdf/0761-06.pdf","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:1636312","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1636312","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Bacteriol","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G7711960441","display_name":"Bacterial Differentiation","funder_award_id":"R01GM054395","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W1505532291","https://openalex.org/W1509057500","https://openalex.org/W1646581831","https://openalex.org/W1663612312","https://openalex.org/W1758794665","https://openalex.org/W1839190629","https://openalex.org/W1939280241","https://openalex.org/W1965079596","https://openalex.org/W1972082695","https://openalex.org/W1993713722","https://openalex.org/W2002400626","https://openalex.org/W2004343635","https://openalex.org/W2013760546","https://openalex.org/W2021606207","https://openalex.org/W2022037801","https://openalex.org/W2034082043","https://openalex.org/W2040126514","https://openalex.org/W2042133316","https://openalex.org/W2048273594","https://openalex.org/W2052373153","https://openalex.org/W2062925988","https://openalex.org/W2075244297","https://openalex.org/W2109105334","https://openalex.org/W2113370582","https://openalex.org/W2114529732","https://openalex.org/W2119982021","https://openalex.org/W2121465131","https://openalex.org/W2127411075","https://openalex.org/W2127564412","https://openalex.org/W2127923318","https://openalex.org/W2131291020","https://openalex.org/W2131553400","https://openalex.org/W2131950604","https://openalex.org/W2136565653","https://openalex.org/W2137075554","https://openalex.org/W2148778250","https://openalex.org/W2159574137","https://openalex.org/W2161425823","https://openalex.org/W2161730552","https://openalex.org/W2167036320","https://openalex.org/W2169432518","https://openalex.org/W3112499720"],"related_works":["https://openalex.org/W7097060140","https://openalex.org/W2013760546","https://openalex.org/W2062925988","https://openalex.org/W2901180016","https://openalex.org/W1494047374","https://openalex.org/W2159102835","https://openalex.org/W2888824598","https://openalex.org/W2049120296","https://openalex.org/W2100004011","https://openalex.org/W2148778250"],"abstract_inverted_index":{"Morphogenetic":[0],"proteins":[1],"such":[2],"as":[3],"SpoVID":[4,38,62,112,183],"and":[5,56,63,68,76,97,111,167,212],"SafA":[6,54,64,110,148,181,193,201,240],"govern":[7],"assembly":[8,75,208,251],"of":[9,25,43,52,83,128,133,139,147,180,192,200,209,249,255],"the":[10,17,23,26,41,49,53,58,100,107,114,129,145,165,169,178,190,198,203,210,253],"Bacillus":[11,89,256],"subtilis":[12],"endospore":[13],"coat":[14,74,211,250],"by":[15],"guiding":[16],"various":[18],"protein":[19,55],"structural":[20],"components":[21],"to":[22,35,40,57,99,158,163,218],"surface":[24],"developing":[27,204],"spore.":[28],"Previously,":[29],"a":[30,44,121],"screen":[31],"for":[32,94],"peptides":[33],"able":[34],"interact":[36],"with":[37,149,182,197,222],"led":[39],"identification":[42],"PYYH":[45,115],"motif":[46,116,243],"present":[47],"in":[48,73,87,174,184,194,252],"C-terminal":[50],"half":[51],"subsequent":[59],"demonstration":[60],"that":[61,106,137,225],"directly":[65,230],"interact.":[66],"spoVID":[67],"safA":[69],"spores":[70],"show":[71,105,136],"deficiencies":[72],"are":[77,85],"lysozyme":[78,213],"susceptible.":[79],"Both":[80],"proteins,":[81],"orthologs":[82],"which":[84],"found":[86],"all":[88],"species,":[90],"have":[91],"LysM":[92,131],"domains":[93],"peptidoglycan":[95],"binding":[96],"localize":[98],"cortex-coat":[101],"interface.":[102],"Here,":[103],"we":[104],"interaction":[108,146,166,179],"between":[109],"involves":[113],"(region":[117,124],"B)":[118],"but":[119],"also":[120],"13-amino-acid":[122],"region":[123,140,175,219,229,234],"A)":[125],"just":[126],"downstream":[127],"N-terminal":[130],"domain":[132],"SafA.":[134],"We":[135],"deletion":[138],"B":[141],"does":[142,152],"not":[143,188],"block":[144],"SpoVID,":[150,223],"nor":[151],"it":[153,161],"bring":[154],"about":[155],"spore":[156,257],"susceptibility":[157],"lysozyme.":[159],"Nevertheless,":[160],"appears":[162],"reduce":[164],"affects":[168],"complex.":[170],"In":[171],"contrast,":[172],"lesions":[173],"A":[176,215,220,235],"impaired":[177],"vitro":[185],"and,":[186],"while":[187],"affecting":[189],"accumulation":[191],"vivo,":[195],"interfered":[196],"localization":[199],"around":[202],"spore,":[205],"causing":[206],"aberrant":[207],"sensitivity.":[214],"peptide":[216],"corresponding":[217],"interacts":[221],"suggesting":[224],"residues":[226],"within":[227],"this":[228,242],"contact":[231],"SpoVID.":[232],"Since":[233],"is":[236],"highly":[237],"conserved":[238],"among":[239],"orthologs,":[241],"may":[244],"be":[245],"an":[246],"important":[247],"determinant":[248],"group":[254],"formers.":[258]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":5},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":3},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}