{"id":"https://openalex.org/W2096476791","doi":"https://doi.org/10.1152/advan.00057.2013","title":"Measuring dynamic kidney function in an undergraduate physiology laboratory","display_name":"Measuring dynamic kidney function in an undergraduate physiology laboratory","publication_year":2013,"publication_date":"2013-11-29","ids":{"openalex":"https://openalex.org/W2096476791","doi":"https://doi.org/10.1152/advan.00057.2013","mag":"2096476791","pmid":"https://pubmed.ncbi.nlm.nih.gov/24292917"},"language":"en","primary_location":{"id":"doi:10.1152/advan.00057.2013","doi":"https://doi.org/10.1152/advan.00057.2013","is_oa":false,"landing_page_url":"https://doi.org/10.1152/advan.00057.2013","pdf_url":null,"source":{"id":"https://openalex.org/S95725323","display_name":"AJP Advances in Physiology Education","issn_l":"1043-4046","issn":["1043-4046","1522-1229"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Physiology Education","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048572637","display_name":"Scott Medler","orcid":"https://orcid.org/0000-0002-7778-0928","observed_orcids":["https://orcid.org/0000-0002-7778-0928"]},"institutions":[{"id":"https://openalex.org/I61032284","display_name":"SUNY Fredonia","ror":"https://ror.org/05vrs0r17","country_code":"US","type":"education","lineage":["https://openalex.org/I61032284"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Scott Medler","raw_affiliation_strings":["Department of Biology, State University of New York, Fredonia, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, State University of New York, Fredonia, New York","institution_ids":["https://openalex.org/I61032284"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059297827","display_name":"Frederick Harrington","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I61032284","display_name":"SUNY Fredonia","ror":"https://ror.org/05vrs0r17","country_code":"US","type":"education","lineage":["https://openalex.org/I61032284"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Frederick Harrington","raw_affiliation_strings":["Department of Biology, State University of New York, Fredonia, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, State University of New York, Fredonia, New York","institution_ids":["https://openalex.org/I61032284"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5048572637"],"corresponding_institution_ids":["https://openalex.org/I61032284"],"apc_list":null,"apc_paid":null,"fwci":0.1821,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.59419949,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"37","issue":"4","first_page":"384","last_page":"391"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14411","display_name":"Undergraduate Neuroscience Education and Research","score":0.23720000684261322,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T14411","display_name":"Undergraduate Neuroscience Education and Research","score":0.23720000684261322,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10072","display_name":"Science Education and Pedagogy","score":0.15690000355243683,"subfield":{"id":"https://openalex.org/subfields/3304","display_name":"Education"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T12327","display_name":"Various Chemistry Research Topics","score":0.10830000042915344,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/renal-physiology","display_name":"renal physiology","score":0.7620000243186951},{"id":"https://openalex.org/keywords/glomerular-filtration-rate","display_name":"glomerular filtration rate","score":0.8970000147819519},{"id":"https://openalex.org/keywords/renal-clearance","display_name":"renal clearance","score":0.9700000286102295},{"id":"https://openalex.org/keywords/glucose-clearance","display_name":"glucose clearance","score":0.9620000123977661},{"id":"https://openalex.org/keywords/serum-creatinine","display_name":"serum creatinine","score":0.9409999847412109},{"id":"https://openalex.org/keywords/urine-concentration","display_name":"urine concentration","score":0.7990000247955322},{"id":"https://openalex.org/keywords/urine-concentrating-mechanism","display_name":"urine concentrating mechanism","score":0.8790000081062317}],"concepts":[{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.5630013942718506},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.5077379941940308},{"id":"https://openalex.org/C509550671","wikidata":"https://www.wikidata.org/wiki/Q126945","display_name":"Medical education","level":1,"score":0.35828179121017456},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.32441243529319763},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3019820749759674},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.11048191785812378}],"mesh":[{"descriptor_ui":"D004504","descriptor_name":"Education, Medical, Undergraduate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007677","descriptor_name":"Kidney Function Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007753","descriptor_name":"Laboratories","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008145","descriptor_name":"Louisiana","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010827","descriptor_name":"Physiology","qualifier_ui":"Q000193","qualifier_name":"education","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1152/advan.00057.2013","doi":"https://doi.org/10.1152/advan.00057.2013","is_oa":false,"landing_page_url":"https://doi.org/10.1152/advan.00057.2013","pdf_url":null,"source":{"id":"https://openalex.org/S95725323","display_name":"AJP Advances in Physiology Education","issn_l":"1043-4046","issn":["1043-4046","1522-1229"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Physiology Education","raw_type":"journal-article"},{"id":"pmid:24292917","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24292917","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in physiology education","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320309644","display_name":"State University of New York","ror":"https://ror.org/01q1z8k08"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1493765591","https://openalex.org/W1516536009","https://openalex.org/W1535773276","https://openalex.org/W1831361360","https://openalex.org/W2011325867","https://openalex.org/W2041403420","https://openalex.org/W2047922146","https://openalex.org/W2068249122","https://openalex.org/W2089814424","https://openalex.org/W2107195787","https://openalex.org/W2169145995","https://openalex.org/W2234807805","https://openalex.org/W4255699209","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W4200593497","https://openalex.org/W4247517854","https://openalex.org/W2332978074","https://openalex.org/W2003330574","https://openalex.org/W130173463","https://openalex.org/W2147099235","https://openalex.org/W2012819837","https://openalex.org/W2409038441","https://openalex.org/W2117460138","https://openalex.org/W4403702350"],"abstract_inverted_index":{"Most":[0],"undergraduate":[1,189],"physiology":[2,190],"laboratories":[3,19,42],"are":[4,112,184],"very":[5],"limited":[6],"in":[7,110,113],"how":[8],"they":[9],"treat":[10],"renal":[11,86],"physiology.":[12],"It":[13],"is":[14],"common":[15],"to":[16,89,130,138,148,171,196],"find":[17],"teaching":[18],"equipped":[20],"with":[21,116],"the":[22,60,63,67,76,154],"capability":[23],"for":[24,153],"high-resolution":[25],"digital":[26],"recordings":[27],"of":[28,49,62,70,84],"physiological":[29,178],"functions":[30],"(muscle":[31],"twitches,":[32],"ECG,":[33],"action":[34],"potentials,":[35],"respiratory":[36],"responses,":[37],"etc.),":[38],"but":[39],"most":[40,188],"urinary":[41],"still":[43],"rely":[44],"on":[45,120],"a":[46,81],"\"dipstick\"":[47],"approach":[48,83],"urinalysis.":[50],"Although":[51],"this":[52],"technique":[53],"can":[54],"provide":[55,80],"some":[56],"basic":[57],"insights":[58],"into":[59],"functioning":[61],"kidneys,":[64],"it":[65],"overlooks":[66],"dynamic":[68],"processes":[69],"filtration,":[71],"reabsorption,":[72,96],"and":[73,99,144,166,176],"secretion.":[74],"In":[75],"present":[77],"article,":[78],"we":[79,125],"straightforward":[82],"using":[85],"clearance":[87],"measurements":[88,109],"estimate":[90],"glomerular":[91,127],"filtration":[92,128],"rate,":[93],"fractional":[94,145,163],"water":[95,146,164],"glucose":[97],"clearance,":[98],"other":[100,177],"physiologically":[101],"relevant":[102],"parameters.":[103,122],"The":[104,180],"estimated":[105],"values":[106],"from":[107],"our":[108],"laboratory":[111,191],"close":[114],"agreement":[115],"those":[117],"anticipated":[118],"based":[119],"textbook":[121],"For":[123],"example,":[124],"found":[126],"rate":[129],"average":[131],"124":[132],"\u00b1":[133,141],"45":[134],"ml/min,":[135],"serum":[136],"creatinine":[137],"be":[139,149,194],"1.23":[140],"0.4":[142],"mg/dl,":[143],"reabsorption":[147,165],"\u223c96.8%.":[150],"Furthermore,":[151],"analyses":[152],"class":[155],"data":[156],"revealed":[157],"significant":[158],"correlations":[159],"between":[160],"parameters":[161],"like":[162],"urine":[167,173],"concentration,":[168],"providing":[169],"opportunities":[170],"discuss":[172],"concentrating":[174],"mechanisms":[175],"processes.":[179],"procedures":[181],"outlined":[182],"here":[183],"general":[185],"enough":[186],"that":[187],"courses":[192],"should":[193],"able":[195],"implement":[197],"them":[198],"without":[199],"difficulty.":[200]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}