{"id":"https://openalex.org/W2095738003","doi":"https://doi.org/10.1016/j.clinthera.2008.10.002","title":"A retrospective study of the use of fluticasone propionate/salmeterol combination as initial asthma controller therapy in a commercially insured population","display_name":"A retrospective study of the use of fluticasone propionate/salmeterol combination as initial asthma controller therapy in a commercially insured population","publication_year":2008,"publication_date":"2008-10-01","ids":{"openalex":"https://openalex.org/W2095738003","doi":"https://doi.org/10.1016/j.clinthera.2008.10.002","mag":"2095738003","pmid":"https://pubmed.ncbi.nlm.nih.gov/19014847"},"language":"en","primary_location":{"id":"doi:10.1016/j.clinthera.2008.10.002","doi":"https://doi.org/10.1016/j.clinthera.2008.10.002","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.clinthera.2008.10.002","pdf_url":null,"source":{"id":"https://openalex.org/S185879095","display_name":"Clinical Therapeutics","issn_l":"0149-2918","issn":["0149-2918","1879-114X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Therapeutics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073126467","display_name":"Howard Steven Friedman","orcid":"https://orcid.org/0000-0002-3528-5136","observed_orcids":["https://orcid.org/0000-0002-3528-5136","https://orcid.org/0000-0003-0568-546X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Howard Friedman","raw_affiliation_strings":["Analytic Solutions, Inc., New York, New York 10012, USA. howard@analytic-consulting.com","Analytic Solutions, Inc., New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Analytic Solutions, Inc., New York, New York 10012, USA. howard@analytic-consulting.com","institution_ids":[]},{"raw_affiliation_string":"Analytic Solutions, Inc., New York, New York","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070961430","display_name":"Teresa K. Wilcox","orcid":"https://orcid.org/0000-0001-9237-7769","observed_orcids":["https://orcid.org/0000-0001-9237-7769"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Teresa Wilcox","raw_affiliation_strings":["United BioSource Corporation, Bethesda, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"United BioSource Corporation, Bethesda, Maryland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016847049","display_name":"Gregory Reardon","orcid":"https://orcid.org/0000-0001-8024-2269","observed_orcids":["https://orcid.org/0000-0001-8024-2269"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gregory Reardon","raw_affiliation_strings":["Informagenics, LLC, Worthington, Ohio"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Informagenics, LLC, Worthington, Ohio","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030354034","display_name":"Simone Crespi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134377","display_name":"New Jersey Department of State","ror":"https://ror.org/04ndw0k24","country_code":"US","type":"government","lineage":["https://openalex.org/I4210134377","https://openalex.org/I4391767959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Simone Crespi","raw_affiliation_strings":["Schering Plough Corp, Kenilworth, New Jersey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Schering Plough Corp, Kenilworth, New Jersey","institution_ids":["https://openalex.org/I4210134377"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059135262","display_name":"Barbara P. Yawn","orcid":"https://orcid.org/0000-0001-7278-5810","observed_orcids":["https://orcid.org/0000-0001-7278-5810"]},"institutions":[{"id":"https://openalex.org/I4210165821","display_name":"Olmsted Medical Center","ror":"https://ror.org/05qa36453","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210165821"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Barbara P. Yawn","raw_affiliation_strings":["Olmsted Medical Center, Minneapolis, Minnesota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Olmsted Medical Center, Minneapolis, Minnesota","institution_ids":["https://openalex.org/I4210165821"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4240,"currency":"USD","value_usd":4240},"apc_paid":null,"fwci":1.7042,"has_fulltext":false,"cited_by_count":18,"citation_normalized_percentile":{"value":0.83114386,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"30","issue":"10","first_page":"1908","last_page":"1917"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12664","display_name":"Clinical practice guidelines implementation","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/salmeterol-fluticasone","display_name":"salmeterol/fluticasone","score":0.9819999933242798},{"id":"https://openalex.org/keywords/asthma-controller-therapy","display_name":"asthma controller therapy","score":0.6460000276565552},{"id":"https://openalex.org/keywords/mild-persistent-asthma","display_name":"mild persistent asthma","score":0.871999979019165},{"id":"https://openalex.org/keywords/inhaled-corticosteroids","display_name":"inhaled corticosteroids","score":0.9120000004768372},{"id":"https://openalex.org/keywords/long-acting-beta-agonists","display_name":"long-acting beta2-agonists","score":0.9660000205039978},{"id":"https://openalex.org/keywords/guideline-adherence","display_name":"guideline adherence","score":0.8709999918937683},{"id":"https://openalex.org/keywords/asthma-severity","display_name":"asthma severity","score":0.7279999852180481},{"id":"https://openalex.org/keywords/commercially-insured-patients","display_name":"commercially insured patients","score":0.7720000147819519}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.954956591129303},{"id":"https://openalex.org/C2776719499","wikidata":"https://www.wikidata.org/wiki/Q424333","display_name":"Salmeterol","level":3,"score":0.8921114206314087},{"id":"https://openalex.org/C2779028295","wikidata":"https://www.wikidata.org/wiki/Q8564098","display_name":"Fluticasone propionate","level":3,"score":0.8821637630462646},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.8655747175216675},{"id":"https://openalex.org/C104863432","wikidata":"https://www.wikidata.org/wiki/Q614304","display_name":"Pharmacy","level":2,"score":0.6437578201293945},{"id":"https://openalex.org/C2781212218","wikidata":"https://www.wikidata.org/wiki/Q1002165","display_name":"Fluticasone","level":3,"score":0.6300131678581238},{"id":"https://openalex.org/C2426938","wikidata":"https://www.wikidata.org/wiki/Q3355478","display_name":"Medical prescription","level":2,"score":0.5849696397781372},{"id":"https://openalex.org/C2776804153","wikidata":"https://www.wikidata.org/wiki/Q210420","display_name":"Corticosteroid","level":2,"score":0.5727218389511108},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.46318742632865906},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.4547700881958008},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.4450336694717407},{"id":"https://openalex.org/C2780724011","wikidata":"https://www.wikidata.org/wiki/Q1295316","display_name":"Emergency department","level":2,"score":0.42195582389831543},{"id":"https://openalex.org/C2779871671","wikidata":"https://www.wikidata.org/wiki/Q637247","display_name":"Formoterol","level":4,"score":0.4196814000606537},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.37088871002197266},{"id":"https://openalex.org/C2776136866","wikidata":"https://www.wikidata.org/wiki/Q422212","display_name":"Budesonide","level":3,"score":0.17966139316558838},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.13272202014923096},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.09862065315246582},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000068297","descriptor_name":"Fluticasone-Salmeterol Drug Combination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000420","descriptor_name":"Albuterol","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000420","descriptor_name":"Albuterol","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D000420","descriptor_name":"Albuterol","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000730","descriptor_name":"Androstadienes","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000730","descriptor_name":"Androstadienes","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D001249","descriptor_name":"Asthma","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D001993","descriptor_name":"Bronchodilator Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D001993","descriptor_name":"Bronchodilator Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004338","descriptor_name":"Drug Combinations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004363","descriptor_name":"Drug Utilization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007345","descriptor_name":"Insurance Claim Review","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007356","descriptor_name":"Insurance, Pharmaceutical Services","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019458","descriptor_name":"Insurance Coverage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.clinthera.2008.10.002","doi":"https://doi.org/10.1016/j.clinthera.2008.10.002","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.clinthera.2008.10.002","pdf_url":null,"source":{"id":"https://openalex.org/S185879095","display_name":"Clinical Therapeutics","issn_l":"0149-2918","issn":["0149-2918","1879-114X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Therapeutics","raw_type":"journal-article"},{"id":"pmid:19014847","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19014847","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical therapeutics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320307770","display_name":"AstraZeneca","ror":"https://ror.org/04r9x1a08"},{"id":"https://openalex.org/F4320307773","display_name":"GlaxoSmithKline","ror":"https://ror.org/01xsqw823"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W387031605","https://openalex.org/W1986566365","https://openalex.org/W1989724865","https://openalex.org/W2002752649","https://openalex.org/W2005106204","https://openalex.org/W2028377192","https://openalex.org/W2042820847","https://openalex.org/W2059196366","https://openalex.org/W2064456460","https://openalex.org/W2073562003","https://openalex.org/W2080649045","https://openalex.org/W2082916208","https://openalex.org/W2122259807","https://openalex.org/W2148583736","https://openalex.org/W2163441905","https://openalex.org/W2331287401","https://openalex.org/W2414310852","https://openalex.org/W4249910788","https://openalex.org/W4250353781","https://openalex.org/W4285719527","https://openalex.org/W6716039114"],"related_works":["https://openalex.org/W2105849353","https://openalex.org/W1973203660","https://openalex.org/W2044990766","https://openalex.org/W1985863718","https://openalex.org/W2169208331","https://openalex.org/W2056689816","https://openalex.org/W2136797108","https://openalex.org/W2005869460","https://openalex.org/W1995379743","https://openalex.org/W2063847617"],"abstract_inverted_index":null,"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}