{"id":"https://openalex.org/W2095360998","doi":"https://doi.org/10.1016/j.brainres.2008.11.093","title":"Oligomeric amyloid-\u03b2(1\u201342) induces THP-1 human monocyte adhesion and maturation","display_name":"Oligomeric amyloid-\u03b2(1\u201342) induces THP-1 human monocyte adhesion and maturation","publication_year":2008,"publication_date":"2008-12-11","ids":{"openalex":"https://openalex.org/W2095360998","doi":"https://doi.org/10.1016/j.brainres.2008.11.093","mag":"2095360998","pmid":"https://pubmed.ncbi.nlm.nih.gov/19101527"},"language":"en","primary_location":{"id":"doi:10.1016/j.brainres.2008.11.093","doi":"https://doi.org/10.1016/j.brainres.2008.11.093","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.brainres.2008.11.093","pdf_url":null,"source":{"id":"https://openalex.org/S96638545","display_name":"Brain Research","issn_l":"0006-8993","issn":["0006-8993","1872-6240"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021119105","display_name":"Nikkilina R. Crouse","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I208333798","display_name":"University of Missouri\u2013St. Louis","ror":"https://ror.org/037cnag11","country_code":"US","type":"education","lineage":["https://openalex.org/I208333798"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nikkilina R. Crouse","raw_affiliation_strings":["Department of Chemistry and Biochemistry and Center for Nanoscience, University of Missouri-St. Louis, One University Boulevard, St. Louis, MO 63121, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry and Center for Nanoscience, University of Missouri-St. Louis, One University Boulevard, St. Louis, MO 63121, USA","institution_ids":["https://openalex.org/I208333798"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074806248","display_name":"Deepa Ajit","orcid":"https://orcid.org/0000-0002-6062-7070","observed_orcids":["https://orcid.org/0000-0002-6062-7070"]},"institutions":[{"id":"https://openalex.org/I208333798","display_name":"University of Missouri\u2013St. Louis","ror":"https://ror.org/037cnag11","country_code":"US","type":"education","lineage":["https://openalex.org/I208333798"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Deepa Ajit","raw_affiliation_strings":["Department of Chemistry and Biochemistry and Center for Nanoscience, University of Missouri-St. Louis, One University Boulevard, St. Louis, MO 63121, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry and Center for Nanoscience, University of Missouri-St. Louis, One University Boulevard, St. Louis, MO 63121, USA","institution_ids":["https://openalex.org/I208333798"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050719363","display_name":"Maria L. D. Udan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I208333798","display_name":"University of Missouri\u2013St. Louis","ror":"https://ror.org/037cnag11","country_code":"US","type":"education","lineage":["https://openalex.org/I208333798"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maria L.D. Udan","raw_affiliation_strings":["Department of Chemistry and Biochemistry and Center for Nanoscience, University of Missouri-St. Louis, One University Boulevard, St. Louis, MO 63121, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry and Center for Nanoscience, University of Missouri-St. Louis, One University Boulevard, St. Louis, MO 63121, USA","institution_ids":["https://openalex.org/I208333798"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051869254","display_name":"Michael R. Nichols","orcid":"https://orcid.org/0000-0001-5458-218X","observed_orcids":["https://orcid.org/0000-0001-5458-218X"]},"institutions":[{"id":"https://openalex.org/I208333798","display_name":"University of Missouri\u2013St. Louis","ror":"https://ror.org/037cnag11","country_code":"US","type":"education","lineage":["https://openalex.org/I208333798"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michael R. Nichols","raw_affiliation_strings":["Department of Chemistry and Biochemistry and Center for Nanoscience, University of Missouri-St. Louis, One University Boulevard, St. Louis, MO 63121, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry and Center for Nanoscience, University of Missouri-St. Louis, One University Boulevard, St. Louis, MO 63121, USA","institution_ids":["https://openalex.org/I208333798"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5051869254"],"corresponding_institution_ids":["https://openalex.org/I208333798"],"apc_list":{"value":3360,"currency":"USD","value_usd":3360},"apc_paid":null,"fwci":0.6768,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.73172568,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"1254","issue":null,"first_page":"109","last_page":"119"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/amyloid-beta-1-42","display_name":"amyloid-beta 42","score":0.9340000152587891},{"id":"https://openalex.org/keywords/amyloid-beta-oligomers","display_name":"amyloid-beta oligomers","score":0.8830000162124634},{"id":"https://openalex.org/keywords/monocyte-adhesion","display_name":"monocyte adhesion","score":0.8650000095367432},{"id":"https://openalex.org/keywords/monocyte-maturation","display_name":"monocyte maturation","score":0.875},{"id":"https://openalex.org/keywords/thp-1-cells","display_name":"THP-1 cells","score":0.9359999895095825},{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.9279999732971191},{"id":"https://openalex.org/keywords/amyloid-beta-aggregation","display_name":"amyloid-beta aggregation","score":0.7799999713897705},{"id":"https://openalex.org/keywords/microglia","display_name":"microglia","score":0.5540000200271606},{"id":"https://openalex.org/keywords/cd11b","display_name":"CD11b","score":0.7770000100135803},{"id":"https://openalex.org/keywords/fibronectin-binding","display_name":"fibronectin binding","score":0.902999997138977},{"id":"https://openalex.org/keywords/phorbol-myristate-acetate","display_name":"phorbol myristate acetate","score":0.8690000176429749}],"concepts":[{"id":"https://openalex.org/C2781184567","wikidata":"https://www.wikidata.org/wiki/Q107244","display_name":"Monocyte","level":2,"score":0.8587208986282349},{"id":"https://openalex.org/C85789140","wikidata":"https://www.wikidata.org/wiki/Q187640","display_name":"Cell adhesion","level":3,"score":0.6157801151275635},{"id":"https://openalex.org/C84416704","wikidata":"https://www.wikidata.org/wiki/Q188666","display_name":"Adhesion","level":2,"score":0.5716140866279602},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5640347003936768},{"id":"https://openalex.org/C2779830541","wikidata":"https://www.wikidata.org/wiki/Q1622829","display_name":"Microglia","level":3,"score":0.5620772242546082},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5376971364021301},{"id":"https://openalex.org/C204258353","wikidata":"https://www.wikidata.org/wiki/Q7670282","display_name":"THP1 cell line","level":3,"score":0.4994535446166992},{"id":"https://openalex.org/C171779818","wikidata":"https://www.wikidata.org/wiki/Q3799301","display_name":"Integrin alpha M","level":3,"score":0.4640710949897766},{"id":"https://openalex.org/C86492073","wikidata":"https://www.wikidata.org/wiki/Q413766","display_name":"Fibronectin","level":3,"score":0.45434969663619995},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3392273187637329},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.3303486108779907},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.30706554651260376},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3039242625236511},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2913525104522705},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2835997939109802},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.2700762152671814},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004797","descriptor_name":"Enzyme-Linked Immunosorbent Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005353","descriptor_name":"Fibronectins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009000","descriptor_name":"Monocytes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009000","descriptor_name":"Monocytes","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009000","descriptor_name":"Monocytes","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D010446","descriptor_name":"Peptide Fragments","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010446","descriptor_name":"Peptide Fragments","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013755","descriptor_name":"Tetradecanoylphorbol Acetate","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D013755","descriptor_name":"Tetradecanoylphorbol Acetate","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D016229","descriptor_name":"Amyloid beta-Peptides","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016229","descriptor_name":"Amyloid beta-Peptides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018625","descriptor_name":"Microscopy, Atomic Force","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020125","descriptor_name":"Mutation, Missense","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D039481","descriptor_name":"CD11b Antigen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D046529","descriptor_name":"Microscopy, Electron, Transmission","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.brainres.2008.11.093","doi":"https://doi.org/10.1016/j.brainres.2008.11.093","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.brainres.2008.11.093","pdf_url":null,"source":{"id":"https://openalex.org/S96638545","display_name":"Brain Research","issn_l":"0006-8993","issn":["0006-8993","1872-6240"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Research","raw_type":"journal-article"},{"id":"pmid:19101527","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19101527","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9476000070571899,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334327","display_name":"School of Medicine, University of Missouri","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":50,"referenced_works":["https://openalex.org/W1577244262","https://openalex.org/W1613451007","https://openalex.org/W1618236677","https://openalex.org/W1651802458","https://openalex.org/W1677883125","https://openalex.org/W1926532709","https://openalex.org/W1969935947","https://openalex.org/W1977010794","https://openalex.org/W1981570625","https://openalex.org/W1984832858","https://openalex.org/W1987568997","https://openalex.org/W1988254695","https://openalex.org/W1991388423","https://openalex.org/W1995650022","https://openalex.org/W2010993726","https://openalex.org/W2014272598","https://openalex.org/W2028288720","https://openalex.org/W2033847972","https://openalex.org/W2038224110","https://openalex.org/W2049167261","https://openalex.org/W2051651977","https://openalex.org/W2057247682","https://openalex.org/W2059804089","https://openalex.org/W2063290148","https://openalex.org/W2067121616","https://openalex.org/W2073516240","https://openalex.org/W2074274825","https://openalex.org/W2075481535","https://openalex.org/W2093067743","https://openalex.org/W2094411486","https://openalex.org/W2097867538","https://openalex.org/W2107015337","https://openalex.org/W2110525047","https://openalex.org/W2117957671","https://openalex.org/W2121963977","https://openalex.org/W2128111072","https://openalex.org/W2133631618","https://openalex.org/W2140139281","https://openalex.org/W2145904082","https://openalex.org/W2149071352","https://openalex.org/W2149399096","https://openalex.org/W2150999725","https://openalex.org/W2165021720","https://openalex.org/W2168025729","https://openalex.org/W2169152986","https://openalex.org/W2221521015","https://openalex.org/W2912432751","https://openalex.org/W4251399438","https://openalex.org/W4296511971","https://openalex.org/W4296759749"],"related_works":["https://openalex.org/W2228608008","https://openalex.org/W1995648866","https://openalex.org/W2519349109","https://openalex.org/W2038659296","https://openalex.org/W1984901953","https://openalex.org/W2147846101","https://openalex.org/W2014428346","https://openalex.org/W2082049432","https://openalex.org/W2317417399","https://openalex.org/W165323934"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}