{"id":"https://openalex.org/W2095292876","doi":"https://doi.org/10.1038/jcbfm.1990.70","title":"Origins and Pathways of Choline Acetyltransferase\u2014Positive Parasympathetic Nerve Fibers to Cerebral Vessels in Rat","display_name":"Origins and Pathways of Choline Acetyltransferase\u2014Positive Parasympathetic Nerve Fibers to Cerebral Vessels in Rat","publication_year":1990,"publication_date":"1990-05-01","ids":{"openalex":"https://openalex.org/W2095292876","doi":"https://doi.org/10.1038/jcbfm.1990.70","mag":"2095292876","pmid":"https://pubmed.ncbi.nlm.nih.gov/2329127"},"language":"en","primary_location":{"id":"doi:10.1038/jcbfm.1990.70","doi":"https://doi.org/10.1038/jcbfm.1990.70","is_oa":true,"landing_page_url":"https://doi.org/10.1038/jcbfm.1990.70","pdf_url":"https://journals.sagepub.com/doi/pdf/10.1038/jcbfm.1990.70?download=true","source":{"id":"https://openalex.org/S89339265","display_name":"Journal of Cerebral Blood Flow & Metabolism","issn_l":"0271-678X","issn":["0271-678X","1559-7016"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cerebral Blood Flow & Metabolism","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://journals.sagepub.com/doi/pdf/10.1038/jcbfm.1990.70?download=true","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100725284","display_name":"Norihiro Suzuki","orcid":"https://orcid.org/0000-0002-0399-6590","observed_orcids":["https://orcid.org/0000-0002-0399-6590"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Norihiro Suzuki","raw_affiliation_strings":["Section of Neurobiology, Department of Medical Cell Research, University of Lund, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Neurobiology, Department of Medical Cell Research, University of Lund, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113585225","display_name":"Jan Erik Hardebo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Jan Erik Hardebo","raw_affiliation_strings":["Section of Neurobiology, Department of Medical Cell Research, University of Lund, Lund, Sweden","Section of Neurology, Department of Medical Cell Research, University of Lund, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Neurobiology, Department of Medical Cell Research, University of Lund, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Section of Neurology, Department of Medical Cell Research, University of Lund, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110238837","display_name":"Christer Owman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Christer Owman","raw_affiliation_strings":["Section of Neurobiology, Department of Medical Cell Research, University of Lund, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Neurobiology, Department of Medical Cell Research, University of Lund, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I187531555"],"apc_list":{"value":4200,"currency":"USD","value_usd":4200},"apc_paid":null,"fwci":3.1695,"has_fulltext":true,"cited_by_count":128,"citation_normalized_percentile":{"value":0.9335388,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"10","issue":"3","first_page":"399","last_page":"408"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.9682999849319458,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.9682999849319458,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.006399999838322401,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14486","display_name":"Cardiovascular, Neuropeptides, and Oxidative Stress Research","score":0.004900000058114529,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/choline-acetyltransferase","display_name":"choline acetyltransferase","score":0.9750000238418579},{"id":"https://openalex.org/keywords/pial-arteries","display_name":"pial arteries","score":0.824999988079071},{"id":"https://openalex.org/keywords/vasoactive-intestinal-peptide","display_name":"vasoactive intestinal peptide","score":0.8960000276565552},{"id":"https://openalex.org/keywords/parasympathetic-nerve-fibers","display_name":"parasympathetic nerve fibers","score":0.8870000243186951},{"id":"https://openalex.org/keywords/sphenopalatine-ganglion","display_name":"sphenopalatine ganglion","score":0.9760000109672546},{"id":"https://openalex.org/keywords/otic-ganglion","display_name":"otic ganglion","score":0.9179999828338623},{"id":"https://openalex.org/keywords/circle-of-willis","display_name":"circle of Willis","score":0.6809999942779541}],"concepts":[{"id":"https://openalex.org/C198399640","wikidata":"https://www.wikidata.org/wiki/Q14863671","display_name":"Choline acetyltransferase","level":3,"score":0.6481677889823914},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4950372278690338},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.45488834381103516},{"id":"https://openalex.org/C2780761756","wikidata":"https://www.wikidata.org/wiki/Q185589","display_name":"Parasympathetic nervous system","level":5,"score":0.41915565729141235},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4032670855522156},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3371592164039612},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.3131965398788452},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.28845280408859253},{"id":"https://openalex.org/C2777372248","wikidata":"https://www.wikidata.org/wiki/Q171064","display_name":"Autonomic nervous system","level":4,"score":0.2150263786315918},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.21220028400421143},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.0},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":true},{"descriptor_ui":"D002795","descriptor_name":"Choline O-Acetyltransferase","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010275","descriptor_name":"Parasympathetic Nervous System","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":true},{"descriptor_ui":"D011919","descriptor_name":"Rats, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1038/jcbfm.1990.70","doi":"https://doi.org/10.1038/jcbfm.1990.70","is_oa":true,"landing_page_url":"https://doi.org/10.1038/jcbfm.1990.70","pdf_url":"https://journals.sagepub.com/doi/pdf/10.1038/jcbfm.1990.70?download=true","source":{"id":"https://openalex.org/S89339265","display_name":"Journal of Cerebral Blood Flow & Metabolism","issn_l":"0271-678X","issn":["0271-678X","1559-7016"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cerebral Blood Flow & Metabolism","raw_type":"journal-article"},{"id":"pmid:2329127","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2329127","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism","raw_type":"Journal Article"},{"id":"pmh:oai:lup.lub.lu.se:216a1304-9ed2-445e-961e-7365c935b297","doi":null,"is_oa":false,"landing_page_url":"https://lup.lub.lu.se/record/1105340","pdf_url":null,"source":{"id":"https://openalex.org/S4306400536","display_name":"Lund University Publications (Lund University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I187531555","host_organization_name":"Lund University","host_organization_lineage":["https://openalex.org/I187531555"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 1559-7016","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1038/jcbfm.1990.70","doi":"https://doi.org/10.1038/jcbfm.1990.70","is_oa":true,"landing_page_url":"https://doi.org/10.1038/jcbfm.1990.70","pdf_url":"https://journals.sagepub.com/doi/pdf/10.1038/jcbfm.1990.70?download=true","source":{"id":"https://openalex.org/S89339265","display_name":"Journal of Cerebral Blood Flow & Metabolism","issn_l":"0271-678X","issn":["0271-678X","1559-7016"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cerebral Blood Flow & Metabolism","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2095292876.pdf","grobid_xml":"https://content.openalex.org/works/W2095292876.grobid-xml"},"referenced_works_count":40,"referenced_works":["https://openalex.org/W1980371181","https://openalex.org/W1985040921","https://openalex.org/W1994202817","https://openalex.org/W1999421009","https://openalex.org/W2001211531","https://openalex.org/W2014783235","https://openalex.org/W2019558153","https://openalex.org/W2025343508","https://openalex.org/W2026084791","https://openalex.org/W2027453864","https://openalex.org/W2029592813","https://openalex.org/W2031754871","https://openalex.org/W2033176779","https://openalex.org/W2038078084","https://openalex.org/W2041498941","https://openalex.org/W2042226260","https://openalex.org/W2045672137","https://openalex.org/W2047608993","https://openalex.org/W2056047007","https://openalex.org/W2061406499","https://openalex.org/W2067770662","https://openalex.org/W2076323907","https://openalex.org/W2084182667","https://openalex.org/W2085335700","https://openalex.org/W2094098610","https://openalex.org/W2095561971","https://openalex.org/W2097104798","https://openalex.org/W2140855900","https://openalex.org/W2151188917","https://openalex.org/W2164620775","https://openalex.org/W2169182236","https://openalex.org/W2308084919","https://openalex.org/W2314926292","https://openalex.org/W2333657729","https://openalex.org/W2342032327","https://openalex.org/W2477603094","https://openalex.org/W2885739897","https://openalex.org/W3014486014","https://openalex.org/W4250579291","https://openalex.org/W4251046829"],"related_works":["https://openalex.org/W2314926292","https://openalex.org/W2056047007","https://openalex.org/W2081944577","https://openalex.org/W2038710433","https://openalex.org/W2443495159","https://openalex.org/W2061406499","https://openalex.org/W2025343508","https://openalex.org/W2029592813","https://openalex.org/W2041512062","https://openalex.org/W4250579291"],"abstract_inverted_index":{"The":[0,137,194,226],"presence":[1],"of":[2,14,21,76,97,121,171,181,224],"cholinergic":[3,74],"nerve":[4,140],"fibers":[5,37,75,113,141,227],"in":[6,63,86,88,118,124,133,144,159,184,242,255],"the":[7,19,31,42,46,95,98,107,125,147,155,160,169,191,197,206,211,216,222,229,238,243,248,256],"brain":[8],"vasculature":[9],"has":[10,38],"been":[11,39],"a":[12,22,51,119,178,202],"matter":[13],"controversy,":[15],"partly":[16],"due":[17],"to":[18,59,106,116,146,188,190,220,237],"lack":[20],"reliable":[23],"histochemical":[24],"marker.":[25],"Accordingly,":[26],"no":[27],"distinct":[28],"information":[29],"about":[30],"origin":[32],"and":[33,128,214,232],"pathways":[34],"for":[35,70],"such":[36,112],"available.":[40],"In":[41],"present":[43,85],"study":[44],"on":[45,205],"rat":[47],"pial":[48,78,139,192],"vasculature,":[49],"utilizing":[50],"choline":[52],"acetyltransferase":[53],"(ChAT)":[54],"antibody,":[55],"which":[56],"is":[57,200],"able":[58],"demonstrate":[60],"this":[61],"enzyme":[62],"peripheral":[64],"nervous":[65],"tissue,":[66],"evidence":[67],"was":[68,84,151],"obtained":[69],"an":[71,252],"innervation":[72],"by":[73,154],"large":[77],"arteries.":[79],"Vasoactive":[80],"intestinal":[81],"polypeptide":[82],"(VIP)":[83],"or":[87],"close":[89],"association":[90],"with":[91,168],"these":[92,185],"fibers.":[93],"By":[94],"aid":[96],"retrograde":[99],"axonal":[100],"tracer":[101],"True":[102],"Blue":[103],"(TB)":[104],"applied":[105],"middle":[108],"cerebral":[109],"arterial":[110],"wall,":[111,209],"were":[114,142,163,174],"shown":[115],"originate":[117],"subgroup":[120],"ChAT-positive":[122,138],"cells":[123,158,172],"sphenopalatine,":[126],"otic,":[127],"internal":[129,217,230,239],"carotid":[130,231,240,244],"ganglia,":[131],"which,":[132],"addition,":[134],"contained":[135],"VIP.":[136],"few":[143,156],"relation":[145],"VIP-immunoreactive":[148],"fibers,":[149],"as":[150,166],"also":[152],"illustrated":[153],"TB-positive":[157],"ganglia":[161,186,234],"that":[162,173],"ChAT":[164],"positive":[165],"compared":[167],"number":[170],"VIP":[175],"positive.":[176],"Only":[177],"small":[179],"population":[180],"ChAT-containing":[182],"neurons":[183],"appeared":[187],"project":[189],"vessels.":[193],"pathway":[195],"from":[196,228,247],"sphenopalatine":[198],"ganglion":[199,250],"via":[201],"membranous":[203],"structure":[204],"medial":[207],"orbital":[208],"through":[210],"ethmoidal":[212,218],"foramen,":[213],"along":[215],"artery":[219,241],"reach":[221],"circle":[223],"Willis.":[225],"otic":[233,249],"probably":[235],"bridge":[236],"canal,":[245],"those":[246],"after":[251],"initial":[253],"course":[254],"lesser":[257],"superficial":[258],"petrosal":[259],"nerve.(ABSTRACT":[260],"TRUNCATED":[261],"AT":[262],"250":[263],"WORDS)":[264]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":4},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}