{"id":"https://openalex.org/W2095162829","doi":"https://doi.org/10.1016/0168-6496(95)00087-9","title":"Transfer of the plasmid RP1 in vivo in germ free mice and in vitro in gut extracts and laboratory media","display_name":"Transfer of the plasmid RP1 in vivo in germ free mice and in vitro in gut extracts and laboratory media","publication_year":1996,"publication_date":"1996-02-01","ids":{"openalex":"https://openalex.org/W2095162829","doi":"https://doi.org/10.1016/0168-6496(95)00087-9","mag":"2095162829"},"language":"en","primary_location":{"id":"doi:10.1016/0168-6496(95)00087-9","doi":"https://doi.org/10.1016/0168-6496(95)00087-9","is_oa":true,"landing_page_url":"https://doi.org/10.1016/0168-6496(95)00087-9","pdf_url":"https://academic.oup.com/femsec/article-pdf/19/2/133/18088824/19-2-133.pdf","source":{"id":"https://openalex.org/S171282171","display_name":"FEMS Microbiology Ecology","issn_l":"0168-6496","issn":["0168-6496","1574-6941"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-2","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEMS Microbiology Ecology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/femsec/article-pdf/19/2/133/18088824/19-2-133.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046100994","display_name":"Camilla Ulla Rang","orcid":"https://orcid.org/0000-0002-3589-7327","observed_orcids":["https://orcid.org/0000-0002-3589-7327"]},"institutions":[{"id":"https://openalex.org/I881427289","display_name":"University of Gothenburg","ror":"https://ror.org/01tm6cn81","country_code":"SE","type":"education","lineage":["https://openalex.org/I881427289"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Camilla U. Rang","raw_affiliation_strings":["Department of General and Marine Microbiology, G\u00f6teborg University, G\u00f6teborg, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General and Marine Microbiology, G\u00f6teborg University, G\u00f6teborg, Sweden","institution_ids":["https://openalex.org/I881427289"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000818507","display_name":"Ruth M. Kennan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I881427289","display_name":"University of Gothenburg","ror":"https://ror.org/01tm6cn81","country_code":"SE","type":"education","lineage":["https://openalex.org/I881427289"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Ruth M. Kennan","raw_affiliation_strings":["Department of General and Marine Microbiology, G\u00f6teborg University, G\u00f6teborg, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General and Marine Microbiology, G\u00f6teborg University, G\u00f6teborg, Sweden","institution_ids":["https://openalex.org/I881427289"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017555502","display_name":"Tore Midtvedt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Tore Midtvedt","raw_affiliation_strings":["Department of Medical Microbial Ecology, Karolinska Institute, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Microbial Ecology, Karolinska Institute, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110265164","display_name":"Lin Chao","orcid":"https://orcid.org/0009-0005-4114-5841","observed_orcids":["https://orcid.org/0009-0005-4114-5841"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lin Chao","raw_affiliation_strings":["Department of Zoology, University of Maryland, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Zoology, University of Maryland, Maryland, USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023950859","display_name":"Patricia L. Conway","orcid":"https://orcid.org/0000-0003-1763-0773","observed_orcids":["https://orcid.org/0000-0003-1763-0773"]},"institutions":[{"id":"https://openalex.org/I31746571","display_name":"UNSW Sydney","ror":"https://ror.org/03r8z3t63","country_code":"AU","type":"education","lineage":["https://openalex.org/I31746571"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Patricia L. Conway","raw_affiliation_strings":["School of Microbiology and Immunology, University of New South Wales, Sydney, NSW, 2052, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Microbiology and Immunology, University of New South Wales, Sydney, NSW, 2052, Australia","institution_ids":["https://openalex.org/I31746571"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5023950859"],"corresponding_institution_ids":["https://openalex.org/I31746571"],"apc_list":{"value":2500,"currency":"GBP","value_usd":3297},"apc_paid":null,"fwci":0.1889,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.54691782,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"19","issue":"2","first_page":"133","last_page":"140"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.8026999831199646,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.8026999831199646,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.1354999989271164,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10943","display_name":"Escherichia coli research studies","score":0.01489999983459711,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/plasmid-conjugation","display_name":"plasmid conjugation","score":0.843999981880188},{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.9539999961853027},{"id":"https://openalex.org/keywords/germ-free-mice","display_name":"germ-free mice","score":0.8999999761581421},{"id":"https://openalex.org/keywords/caecal-contents","display_name":"caecal contents","score":0.949999988079071},{"id":"https://openalex.org/keywords/liquid-medium","display_name":"liquid media","score":0.6539999842643738},{"id":"https://openalex.org/keywords/transfer-frequency","display_name":"transfer frequency","score":0.7129999995231628}],"concepts":[{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.827038049697876},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8199425935745239},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.6892743706703186},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.6759881377220154},{"id":"https://openalex.org/C2778660310","wikidata":"https://www.wikidata.org/wiki/Q177998","display_name":"Agar","level":3,"score":0.6719166040420532},{"id":"https://openalex.org/C22744801","wikidata":"https://www.wikidata.org/wiki/Q172778","display_name":"Plasmid","level":3,"score":0.46771472692489624},{"id":"https://openalex.org/C3018023364","wikidata":"https://www.wikidata.org/wiki/Q425265","display_name":"Significant difference","level":2,"score":0.44933387637138367},{"id":"https://openalex.org/C62643968","wikidata":"https://www.wikidata.org/wiki/Q574816","display_name":"Agar plate","level":3,"score":0.4315837323665619},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.4251033663749695},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.2489084005355835},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.21031519770622253},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.11029735207557678},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.07363387942314148},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.07169851660728455},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.06611070036888123},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0649193823337555},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1016/0168-6496(95)00087-9","doi":"https://doi.org/10.1016/0168-6496(95)00087-9","is_oa":true,"landing_page_url":"https://doi.org/10.1016/0168-6496(95)00087-9","pdf_url":"https://academic.oup.com/femsec/article-pdf/19/2/133/18088824/19-2-133.pdf","source":{"id":"https://openalex.org/S171282171","display_name":"FEMS Microbiology Ecology","issn_l":"0168-6496","issn":["0168-6496","1574-6941"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-2","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEMS Microbiology Ecology","raw_type":"journal-article"},{"id":"doi:10.1111/j.1574-6941.1996.tb00206.x","doi":"https://doi.org/10.1111/j.1574-6941.1996.tb00206.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1574-6941.1996.tb00206.x","pdf_url":null,"source":{"id":"https://openalex.org/S171282171","display_name":"FEMS Microbiology Ecology","issn_l":"0168-6496","issn":["0168-6496","1574-6941"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-2","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEMS Microbiology Ecology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/0168-6496(95)00087-9","doi":"https://doi.org/10.1016/0168-6496(95)00087-9","is_oa":true,"landing_page_url":"https://doi.org/10.1016/0168-6496(95)00087-9","pdf_url":"https://academic.oup.com/femsec/article-pdf/19/2/133/18088824/19-2-133.pdf","source":{"id":"https://openalex.org/S171282171","display_name":"FEMS Microbiology Ecology","issn_l":"0168-6496","issn":["0168-6496","1574-6941"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-2","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEMS Microbiology Ecology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322315","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691"},{"id":"https://openalex.org/F4320322579","display_name":"Naturv\u00e5rdsverket","ror":"https://ror.org/02y7nf053"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2095162829.pdf","grobid_xml":"https://content.openalex.org/works/W2095162829.grobid-xml"},"referenced_works_count":24,"referenced_works":["https://openalex.org/W1513717105","https://openalex.org/W1670015181","https://openalex.org/W1857370875","https://openalex.org/W1933803127","https://openalex.org/W1941753592","https://openalex.org/W1976021097","https://openalex.org/W1992835387","https://openalex.org/W2028227437","https://openalex.org/W2038515430","https://openalex.org/W2100971121","https://openalex.org/W2103274496","https://openalex.org/W2106274663","https://openalex.org/W2118383882","https://openalex.org/W2124868676","https://openalex.org/W2130386874","https://openalex.org/W2144164155","https://openalex.org/W2144634347","https://openalex.org/W2144695526","https://openalex.org/W2166228461","https://openalex.org/W2169358239","https://openalex.org/W2238627544","https://openalex.org/W2320145017","https://openalex.org/W2489019921","https://openalex.org/W2897083262"],"related_works":["https://openalex.org/W2137325668","https://openalex.org/W2075228246","https://openalex.org/W2345298686","https://openalex.org/W2102001744","https://openalex.org/W2101938931","https://openalex.org/W2126872257","https://openalex.org/W2111280431","https://openalex.org/W1967289919","https://openalex.org/W6981303935","https://openalex.org/W1836987"],"abstract_inverted_index":{"The":[0,49,161,199,267],"frequency":[1,86,111,130,143,201],"of":[2,5,52,87,93,128,243,272,275],"conjugal":[3],"transfer":[4,50,88,129,187,200,257],"the":[6,21,53,94,126,132,136,182,186,224,230,238,244,249,270,283],"plasmid":[7,54,137],"RP1":[8],"from":[9,55,66,91,152,156,190,193,209],"two":[10,133,225],"different":[11,65,134],"Escherichia":[12],"coli":[13,24],"donor":[14,115,210],"strains":[15],"(HB101":[16],"and":[17,36,43,46,58,106,146,185,213,233],"X7,":[18,56,96,153,194,211],"RifR)":[19],"to":[20,79],"same":[22,162],"E.":[23],"recipient":[25],"strain":[26],"(X7,":[27],"NalR)":[28],"was":[29,89,112,164,180,188,206],"measured":[30],"in":[31,37,60,80,85,110,144,147,148,168,202,264],"vivo":[32,61,145,265],"(germ":[33],"free":[34],"mice)":[35],"vitro":[38,149,169],"(intestinal":[39],"extracts,":[40],"caecal":[41,74,150,234],"contents":[42,151,235],"laboratory":[44,100,119,178,203,245,259],"liquid":[45,101,204],"agar":[47,120,179,260],"media).":[48],"frequencies":[51],"RifR":[57,97,154,195,212],"HB101":[59,116,157,191],"were":[62],"not":[63,262],"significantly":[64],"those":[67],"obtained":[68,90],"when":[69,98,117,166,177],"using":[70,99,118,167,258,273],"intestinal":[71,170,231],"extracts":[72,171,232],"or":[73],"contents.":[75],"In":[76,175],"contrast,":[77,176],"compared":[78],"vivo,":[81],"a":[82,107,141,279],"significant":[83,108,215],"difference":[84,109,216],"one":[92],"donors,":[95,135],"media":[102,205,246],"(P":[103,121,158,172,196,217],"<":[104,122,159,197],"0.05)":[105,219],"noted":[113],"for":[114,248,281],"0.01).":[123],"When":[124],"comparing":[125],"ratio":[127],"between":[131,223],"consistently":[138],"transferred":[139],"at":[140],"higher":[142],"than":[155,192,241],"0.05).":[160,174,198],"pattern":[163],"observed":[165],">":[173,218],"used,":[181],"opposite":[183],"occurred":[184],"greater":[189],"highly":[207],"variable":[208],"no":[214],"could":[220],"be":[221],"seen":[222],"donors.":[226],"We":[227],"conclude":[228],"that":[229,256],"better":[236],"reflect":[237,263],"natural":[239],"environment":[240],"any":[242],"tested":[247],"parameter":[250],"investigated.":[251],"Furthermore,":[252],"it":[253],"is":[254],"shown":[255],"did":[261],"conditions.":[266],"data":[268],"supports":[269],"concept":[271],"sub-samples":[274],"an":[276],"ecosystem":[277],"as":[278],"microcosm":[280],"modelling":[282],"ecosystem.":[284]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}