{"id":"https://openalex.org/W2095097110","doi":"https://doi.org/10.1186/1755-8794-1-24","title":"Genotyping panel for assessing response to cancer chemotherapy","display_name":"Genotyping panel for assessing response to cancer chemotherapy","publication_year":2008,"publication_date":"2008-06-11","ids":{"openalex":"https://openalex.org/W2095097110","doi":"https://doi.org/10.1186/1755-8794-1-24","mag":"2095097110","pmid":"https://pubmed.ncbi.nlm.nih.gov/18547414","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2442111"},"language":"en","primary_location":{"id":"doi:10.1186/1755-8794-1-24","doi":"https://doi.org/10.1186/1755-8794-1-24","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1755-8794-1-24","pdf_url":"https://bmcmedgenomics.biomedcentral.com/counter/pdf/10.1186/1755-8794-1-24","source":{"id":"https://openalex.org/S119250532","display_name":"BMC Medical Genomics","issn_l":"1755-8794","issn":["1755-8794"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Genomics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcmedgenomics.biomedcentral.com/counter/pdf/10.1186/1755-8794-1-24","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110097012","display_name":"Zunyan Dai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Zunyan Dai","raw_affiliation_strings":["Program in Pharmacogenomics, Department of Pharmacology, Comprehensive Cancer Center, College of Medicine and Public Health, The Ohio State University, 5072 Graves Hall, 333 West 10th Avenue, Columbus, OH 43210-1239, USA. dai.15@osu.edu","Program in Pharmacogenomics, Department of Pharmacology, Comprehensive Cancer Center, College of Medicine and Public Health, The Ohio State University, 5072 Graves Hall, 333 West 10th Avenue, Columbus, OH, 43210-1239, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Program in Pharmacogenomics, Department of Pharmacology, Comprehensive Cancer Center, College of Medicine and Public Health, The Ohio State University, 5072 Graves Hall, 333 West 10th Avenue, Columbus, OH 43210-1239, USA. dai.15@osu.edu","institution_ids":["https://openalex.org/I52357470"]},{"raw_affiliation_string":"Program in Pharmacogenomics, Department of Pharmacology, Comprehensive Cancer Center, College of Medicine and Public Health, The Ohio State University, 5072 Graves Hall, 333 West 10th Avenue, Columbus, OH, 43210-1239, USA","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108534149","display_name":"Audrey C. Papp","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Audrey C Papp","raw_affiliation_strings":["Program in Pharmacogenomics, Department of Pharmacology, Comprehensive Cancer Center, College of Medicine and Public Health, The Ohio State University, 5072 Graves Hall, 333 West 10th Avenue, Columbus, OH, 43210-1239, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Program in Pharmacogenomics, Department of Pharmacology, Comprehensive Cancer Center, College of Medicine and Public Health, The Ohio State University, 5072 Graves Hall, 333 West 10th Avenue, Columbus, OH, 43210-1239, USA","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067885487","display_name":"Daqing Wang","orcid":"https://orcid.org/0000-0002-7134-3065","observed_orcids":["https://orcid.org/0000-0002-7134-3065"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Danxin Wang","raw_affiliation_strings":["Program in Pharmacogenomics, Department of Pharmacology, Comprehensive Cancer Center, College of Medicine and Public Health, The Ohio State University, 5072 Graves Hall, 333 West 10th Avenue, Columbus, OH, 43210-1239, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Program in Pharmacogenomics, Department of Pharmacology, Comprehensive Cancer Center, College of Medicine and Public Health, The Ohio State University, 5072 Graves Hall, 333 West 10th Avenue, Columbus, OH, 43210-1239, USA","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012798070","display_name":"Heather Hampel","orcid":"https://orcid.org/0000-0001-7558-9794","observed_orcids":["https://orcid.org/0000-0001-7558-9794"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Heather Hampel","raw_affiliation_strings":["Division of Human Genetics, College of Medicine and Public Health, The Ohio State University, 2050 Kenny Road, 8th floor tower, Columbus, OH, 43221, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Human Genetics, College of Medicine and Public Health, The Ohio State University, 2050 Kenny Road, 8th floor tower, Columbus, OH, 43221, USA","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062174660","display_name":"Wolfgang Sad\u00e9e","orcid":"https://orcid.org/0000-0003-1894-6374","observed_orcids":["https://orcid.org/0000-0003-1894-6374"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Wolfgang Sadee","raw_affiliation_strings":["Program in Pharmacogenomics, Department of Pharmacology, Comprehensive Cancer Center, College of Medicine and Public Health, The Ohio State University, 5072 Graves Hall, 333 West 10th Avenue, Columbus, OH, 43210-1239, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Program in Pharmacogenomics, Department of Pharmacology, Comprehensive Cancer Center, College of Medicine and Public Health, The Ohio State University, 5072 Graves Hall, 333 West 10th Avenue, Columbus, OH, 43210-1239, USA","institution_ids":["https://openalex.org/I52357470"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5062174660","https://openalex.org/A5110097012"],"corresponding_institution_ids":["https://openalex.org/I52357470"],"apc_list":{"value":3190,"currency":"USD","value_usd":3190},"apc_paid":{"value":3190,"currency":"USD","value_usd":3190},"fwci":1.8782,"has_fulltext":true,"cited_by_count":26,"citation_normalized_percentile":{"value":0.83384973,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"1","issue":"1","first_page":"24","last_page":"24"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.0034000000450760126,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chemoresistance","display_name":"chemoresistance","score":0.6940000057220459},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.8069999814033508},{"id":"https://openalex.org/keywords/candidate-genes","display_name":"candidate genes","score":0.7549999952316284},{"id":"https://openalex.org/keywords/chronic-lymphocytic-leukemia","display_name":"chronic lymphocytic leukemia","score":0.8769999742507935},{"id":"https://openalex.org/keywords/flavopiridol","display_name":"flavopiridol","score":0.902999997138977},{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"colorectal cancer","score":0.9980000257492065},{"id":"https://openalex.org/keywords/cyp2d6","display_name":"CYP2D6","score":0.9819999933242798},{"id":"https://openalex.org/keywords/ugt1a1-promoter-polymorphism","display_name":"UGT1A1 promoter polymorphism","score":0.9240000247955322},{"id":"https://openalex.org/keywords/pharmacogenomics","display_name":"pharmacogenomics","score":0.5849999785423279},{"id":"https://openalex.org/keywords/inter-individual-variability","display_name":"interindividual variability","score":0.6990000009536743},{"id":"https://openalex.org/keywords/pharmacogenes","display_name":"drug metabolism genes","score":0.5799999833106995},{"id":"https://openalex.org/keywords/genetic-biomarkers","display_name":"genetic biomarkers","score":0.8230000138282776}],"concepts":[{"id":"https://openalex.org/C31467283","wikidata":"https://www.wikidata.org/wiki/Q912147","display_name":"Genotyping","level":4,"score":0.8755826950073242},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7075197696685791},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.668803334236145},{"id":"https://openalex.org/C170734499","wikidata":"https://www.wikidata.org/wiki/Q1152227","display_name":"Pharmacogenomics","level":2,"score":0.48615762591362},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.4650721549987793},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4171896278858185},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.41342025995254517},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3209763467311859},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.31176096200942993},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.18498766422271729},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1186/1755-8794-1-24","doi":"https://doi.org/10.1186/1755-8794-1-24","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1755-8794-1-24","pdf_url":"https://bmcmedgenomics.biomedcentral.com/counter/pdf/10.1186/1755-8794-1-24","source":{"id":"https://openalex.org/S119250532","display_name":"BMC Medical Genomics","issn_l":"1755-8794","issn":["1755-8794"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Genomics","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2442111","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2442111","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Med Genomics","raw_type":"Text"},{"id":"pmid:18547414","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18547414","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC medical genomics","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:30e7374452d944ff90ca9f7ad54adacd","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/30e7374452d944ff90ca9f7ad54adacd","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Medical Genomics, Vol 1, Iss 1, p 24 (2008)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/1755-8794-1-24","doi":"https://doi.org/10.1186/1755-8794-1-24","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1755-8794-1-24","pdf_url":"https://bmcmedgenomics.biomedcentral.com/counter/pdf/10.1186/1755-8794-1-24","source":{"id":"https://openalex.org/S119250532","display_name":"BMC Medical Genomics","issn_l":"1755-8794","issn":["1755-8794"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Genomics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4661810536","display_name":"Pharmacogenomics of Membrane Transporters","funder_award_id":"U19GM061390","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G8724718177","display_name":"Pharmacogenetics of Membrane Transporters","funder_award_id":"U01GM061390","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2095097110.pdf","grobid_xml":"https://content.openalex.org/works/W2095097110.grobid-xml"},"referenced_works_count":56,"referenced_works":["https://openalex.org/W185146199","https://openalex.org/W1509099686","https://openalex.org/W1527568400","https://openalex.org/W1536672368","https://openalex.org/W1908561757","https://openalex.org/W1968006026","https://openalex.org/W1971336136","https://openalex.org/W1972020976","https://openalex.org/W1982167929","https://openalex.org/W1982335109","https://openalex.org/W1985764154","https://openalex.org/W1987152771","https://openalex.org/W1988658163","https://openalex.org/W1989977248","https://openalex.org/W1992297716","https://openalex.org/W1996783118","https://openalex.org/W2011197968","https://openalex.org/W2011562383","https://openalex.org/W2011628325","https://openalex.org/W2012711528","https://openalex.org/W2014656993","https://openalex.org/W2027504487","https://openalex.org/W2029035130","https://openalex.org/W2037691949","https://openalex.org/W2038717263","https://openalex.org/W2039141364","https://openalex.org/W2046674864","https://openalex.org/W2055786949","https://openalex.org/W2055904567","https://openalex.org/W2058864686","https://openalex.org/W2069145367","https://openalex.org/W2089720722","https://openalex.org/W2097090021","https://openalex.org/W2098224238","https://openalex.org/W2098867544","https://openalex.org/W2099154608","https://openalex.org/W2111020493","https://openalex.org/W2111980171","https://openalex.org/W2112565258","https://openalex.org/W2118469659","https://openalex.org/W2121592758","https://openalex.org/W2121917437","https://openalex.org/W2127449669","https://openalex.org/W2131164389","https://openalex.org/W2131759788","https://openalex.org/W2146683645","https://openalex.org/W2147549027","https://openalex.org/W2147689513","https://openalex.org/W2162784517","https://openalex.org/W2163442941","https://openalex.org/W2168114725","https://openalex.org/W2324992276","https://openalex.org/W2328946792","https://openalex.org/W2435087549","https://openalex.org/W4237160359","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2314836908","https://openalex.org/W3117315908","https://openalex.org/W2002574199","https://openalex.org/W2804449317","https://openalex.org/W2734382735","https://openalex.org/W2168149377","https://openalex.org/W2093731007","https://openalex.org/W2163986451","https://openalex.org/W1988658163","https://openalex.org/W4404638842"],"abstract_inverted_index":{"BACKGROUND:":[0],"Variants":[1],"in":[2,23,65,84,89,173],"numerous":[3],"genes":[4,21,63,87],"are":[5],"thought":[6],"to":[7,36,53,91,100,165,170,187],"affect":[8],"the":[9,49,147,185],"success":[10],"or":[11],"failure":[12],"of":[13,48,177],"cancer":[14],"chemotherapy.":[15,93],"Interindividual":[16],"variability":[17,172],"can":[18],"result":[19],"from":[20],"involved":[22,64],"drug":[24,28,163,174],"metabolism":[25],"and":[26,33,44,67,69,110,139],"transport,":[27],"targets":[29],"(receptors,":[30],"enzymes,":[31],"etc),":[32],"proteins":[34],"relevant":[35],"cell":[37,40],"survival":[38],"(e.g.,":[39],"cycle,":[41],"DNA":[42],"repair,":[43],"apoptosis).":[45],"The":[46,95],"purpose":[47],"current":[50],"study":[51],"is":[52,157],"establish":[54],"a":[55],"flexible,":[56],"cost-effective,":[57],"high-throughput":[58],"genotyping":[59,78,96,121,124,155],"platform":[60],"for":[61,77,128,136,146,159,191],"candidate":[62,86],"chemoresistance":[66],"-sensitivity,":[68],"treatment":[70],"outcomes.":[71],"METHODS:":[72],"We":[73],"have":[74],"adopted":[75],"SNPlex":[76],"432":[79],"single":[80],"nucleotide":[81],"polymorphisms":[82,129,167],"(SNPs)":[83],"160":[85],"implicated":[88],"response":[90],"anticancer":[92,162,193],"RESULTS:":[94],"panels":[97],"were":[98,126],"applied":[99],"39":[101],"patients":[102,112],"with":[103,113,142],"chronic":[104],"lymphocytic":[105],"leukemia":[106],"undergoing":[107],"flavopiridol":[108],"chemotherapy,":[109],"90":[111],"colorectal":[114],"cancer.":[115],"408":[116],"SNPs":[117],"(94%)":[118],"produced":[119],"successful":[120],"results.":[122],"Additional":[123],"methods":[125],"established":[127],"undetectable":[130],"by":[131],"SNPlex,":[132],"including":[133],"multiplexed":[134],"SNaPshot":[135],"CYP2D6":[137],"SNPs,":[138],"PCR":[140],"amplification":[141],"fluorescently":[143],"labeled":[144],"primers":[145],"UGT1A1":[148],"promoter":[149],"(TA)nTAA":[150],"repeat":[151],"polymorphism.":[152],"CONCLUSION:":[153],"This":[154],"panel":[156],"useful":[158],"supporting":[160],"clinical":[161],"trials":[164],"identify":[166],"that":[168],"contribute":[169],"interindividual":[171],"response.":[175],"Availability":[176],"population":[178],"genetic":[179,189],"data":[180],"across":[181],"multiple":[182],"studies":[183],"has":[184],"potential":[186],"yield":[188],"biomarkers":[190],"optimizing":[192],"therapy.":[194]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}
