{"id":"https://openalex.org/W2094579852","doi":"https://doi.org/10.1177/197140091102400411","title":"New Imaging Strategies in Degenerative Disease of the Intervertebral Disks: Functional Spine Imaging","display_name":"New Imaging Strategies in Degenerative Disease of the Intervertebral Disks: Functional Spine Imaging","publication_year":2011,"publication_date":"2011-08-01","ids":{"openalex":"https://openalex.org/W2094579852","doi":"https://doi.org/10.1177/197140091102400411","mag":"2094579852","pmid":"https://pubmed.ncbi.nlm.nih.gov/24059713"},"language":"en","primary_location":{"id":"doi:10.1177/197140091102400411","doi":"https://doi.org/10.1177/197140091102400411","is_oa":false,"landing_page_url":"https://doi.org/10.1177/197140091102400411","pdf_url":null,"source":{"id":"https://openalex.org/S191059882","display_name":"The Neuroradiology Journal","issn_l":"1971-4009","issn":["1971-4009","2385-1996"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Neuroradiology Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113780674","display_name":"V. H. Haughton","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799905417","display_name":"UW Health University Hospital","ror":"https://ror.org/02mqqhj42","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I135310074","https://openalex.org/I2799905417","https://openalex.org/I4210132596"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"V. Haughton","raw_affiliation_strings":["Radiology Department, Wisconsin University Hospitals; Madison, Wisconsin, USA","Madison, Wisconsin, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radiology Department, Wisconsin University Hospitals; Madison, Wisconsin, USA","institution_ids":["https://openalex.org/I2799905417"]},{"raw_affiliation_string":"Madison, Wisconsin, USA","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5113780674"],"corresponding_institution_ids":["https://openalex.org/I2799905417"],"apc_list":{"value":4150,"currency":"USD","value_usd":4150},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.19219173,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"24","issue":"4","first_page":"560","last_page":"563"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10238","display_name":"Spine and Intervertebral Disc Pathology","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10238","display_name":"Spine and Intervertebral Disc Pathology","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11518","display_name":"Cervical and Thoracic Myelopathy","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intervertebral-disc-degeneration","display_name":"intervertebral disc degeneration","score":0.9089999794960022},{"id":"https://openalex.org/keywords/mr-spectroscopy","display_name":"MR spectroscopy","score":0.7289999723434448},{"id":"https://openalex.org/keywords/lactic-acid","display_name":"lactic acid","score":0.8820000290870667},{"id":"https://openalex.org/keywords/glycosaminoglycans","display_name":"glycosaminoglycans","score":0.984000027179718},{"id":"https://openalex.org/keywords/disc-herniation","display_name":"disc herniation","score":0.6740000247955322},{"id":"https://openalex.org/keywords/back-pain","display_name":"back pain","score":0.7639999985694885},{"id":"https://openalex.org/keywords/neck-pain","display_name":"neck pain","score":0.9290000200271606},{"id":"https://openalex.org/keywords/diffusion-imaging","display_name":"diffusion imaging","score":0.6970000267028809},{"id":"https://openalex.org/keywords/t2-relaxation-time","display_name":"T2 relaxation time","score":0.9440000057220459},{"id":"https://openalex.org/keywords/dynamic-imaging","display_name":"dynamic imaging","score":0.8550000190734863}],"concepts":[{"id":"https://openalex.org/C3018239782","wikidata":"https://www.wikidata.org/wiki/Q502781","display_name":"Intervertebral disk","level":3,"score":0.6308088302612305},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6221726536750793},{"id":"https://openalex.org/C103191249","wikidata":"https://www.wikidata.org/wiki/Q624073","display_name":"In vivo magnetic resonance spectroscopy","level":3,"score":0.6211767196655273},{"id":"https://openalex.org/C2778051963","wikidata":"https://www.wikidata.org/wiki/Q11773731","display_name":"Degenerative disc disease","level":3,"score":0.552306056022644},{"id":"https://openalex.org/C2775920511","wikidata":"https://www.wikidata.org/wiki/Q161249","display_name":"Lactic acid","level":3,"score":0.5255526304244995},{"id":"https://openalex.org/C182752723","wikidata":"https://www.wikidata.org/wiki/Q1474590","display_name":"Functional imaging","level":2,"score":0.5139946341514587},{"id":"https://openalex.org/C2777910003","wikidata":"https://www.wikidata.org/wiki/Q1707292","display_name":"Asymptomatic","level":2,"score":0.47365984320640564},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.44131603837013245},{"id":"https://openalex.org/C149550507","wikidata":"https://www.wikidata.org/wiki/Q899360","display_name":"Diffusion MRI","level":3,"score":0.4352670907974243},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.42683786153793335},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.41080474853515625},{"id":"https://openalex.org/C44575665","wikidata":"https://www.wikidata.org/wiki/Q1293405","display_name":"Lumbar","level":2,"score":0.23412436246871948},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.22400301694869995},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.10538661479949951},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1177/197140091102400411","doi":"https://doi.org/10.1177/197140091102400411","is_oa":false,"landing_page_url":"https://doi.org/10.1177/197140091102400411","pdf_url":null,"source":{"id":"https://openalex.org/S191059882","display_name":"The Neuroradiology Journal","issn_l":"1971-4009","issn":["1971-4009","2385-1996"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Neuroradiology Journal","raw_type":"journal-article"},{"id":"pmid:24059713","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24059713","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The neuroradiology journal","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W1876323218","https://openalex.org/W1880821811","https://openalex.org/W1963256207","https://openalex.org/W1997644281","https://openalex.org/W2017263949","https://openalex.org/W2021412978","https://openalex.org/W2031630422","https://openalex.org/W2054483563","https://openalex.org/W2058642058","https://openalex.org/W2063518237","https://openalex.org/W2063688349","https://openalex.org/W2067359866","https://openalex.org/W2072231553","https://openalex.org/W2076964610","https://openalex.org/W2082198144","https://openalex.org/W2131520279","https://openalex.org/W2151309748","https://openalex.org/W2169785360","https://openalex.org/W2170748431","https://openalex.org/W2315256283"],"related_works":["https://openalex.org/W2131650116","https://openalex.org/W1988111853","https://openalex.org/W2106655863","https://openalex.org/W4405671592","https://openalex.org/W4384458169","https://openalex.org/W2109900244","https://openalex.org/W2170326292","https://openalex.org/W2056689352","https://openalex.org/W1976331929","https://openalex.org/W2977732886"],"abstract_inverted_index":{"As":[0],"it":[1,44],"does":[2,45],"for":[3,84],"the":[4,14,18,37,53,65,74,80,95,102,124,143,145,170,178],"brain,":[5],"functional":[6,128],"imaging":[7,29,63,93],"provides":[8],"additional":[9],"clinically":[10],"valuable":[11],"information":[12],"on":[13],"spine,":[15,66],"especially":[16],"in":[17,52,59,151,172],"problem":[19],"of":[20,36,64,76,82,94,101,118,126,169,180],"back":[21],"and":[22,70,79,113,154,159],"neck":[23],"pain.":[24],"While":[25],"conventional":[26],"anatomic":[27],"spine":[28,96],"demonstrates":[30,134],"many":[31],"abnormalities,":[32],"such":[33],"as":[34],"herniation":[35],"intervertebral":[38],"disk,":[39,144],"with":[40],"nearly":[41],"perfect":[42],"accuracy,":[43],"not":[46],"effectively":[47,192],"distinguish":[48],"incidental":[49],"degenerative":[50],"changes":[51],"disk":[54,171],"from":[55,195],"those":[56],"that":[57,87,137,147],"results":[58],"pain":[60],"production.":[61],"Functional":[62,92],"still":[67],"under":[68,90],"development":[69],"evaluation,":[71],"will":[72],"facilitate":[73],"identification":[75],"painful":[77,173],"disks":[78],"selection":[81],"patients":[83],"innovative":[85],"treatments":[86],"are":[88],"presently":[89],"development.":[91],"includes:":[97],"MR":[98,129,132,152],"spectroscopy,":[99],"fMRI":[100],"spinal":[103],"cord,":[104],"diffusion":[105],"imaging,":[106],"T2":[107],"relaxation":[108],"time,":[109],"T1":[110],"rho":[111],"measurement":[112],"dynamic":[114],"imaging.":[115],"The":[116],"purpose":[117],"this":[119],"presentation":[120],"is":[121,183],"to":[122],"review":[123],"status":[125],"these":[127],"techniques.":[130],"MRS:":[131],"spectroscopy":[133],"tissue":[135],"constituents":[136],"have":[138],"characteristic":[139],"resonant":[140],"frequencies.":[141],"For":[142],"substances":[146],"can":[148],"be":[149],"recognized":[150],"spectra":[153],"quantified":[155],"include":[156],"lactic":[157,181,189],"acid":[158,162,182,190],"glycosaminoglycans.":[160],"Lactic":[161],"has":[163],"been":[164],"documented":[165],"by":[166],"direct":[167],"sampling":[168],"degenerating":[174,197],"disks.":[175,198],"With":[176],"MRS,":[177],"concentration":[179,191],"measured":[184],"non-invasively.":[185],"In":[186],"pilot":[187],"studies,":[188],"distinguishes":[193],"symptomatic":[194],"asymptomatic":[196]},"counts_by_year":[{"year":2016,"cited_by_count":1}],"updated_date":"2026-10-08T09:06:37.294493","created_date":"2016-06-24T00:00:00"}