{"id":"https://openalex.org/W2094573310","doi":"https://doi.org/10.1016/j.mcn.2004.08.019","title":"Mechanism of SNARE protein binding and regulation of Cav2 channels by phosphorylation of the synaptic protein interaction site","display_name":"Mechanism of SNARE protein binding and regulation of Cav2 channels by phosphorylation of the synaptic protein interaction site","publication_year":2004,"publication_date":"2004-12-13","ids":{"openalex":"https://openalex.org/W2094573310","doi":"https://doi.org/10.1016/j.mcn.2004.08.019","mag":"2094573310","pmid":"https://pubmed.ncbi.nlm.nih.gov/15607937"},"language":"en","primary_location":{"id":"doi:10.1016/j.mcn.2004.08.019","doi":"https://doi.org/10.1016/j.mcn.2004.08.019","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.mcn.2004.08.019","pdf_url":null,"source":{"id":"https://openalex.org/S47891569","display_name":"Molecular and Cellular Neuroscience","issn_l":"1044-7431","issn":["1044-7431","1095-9327"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Cellular Neuroscience","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113991048","display_name":"Charles T. Yokoyama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles T. Yokoyama","raw_affiliation_strings":["Department of Pharmacology, University of Washington, Seattle, WA 98195, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, University of Washington, Seattle, WA 98195, USA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017011355","display_name":"Scott J. Myers","orcid":"https://orcid.org/0000-0002-6689-3978","observed_orcids":["https://orcid.org/0000-0002-6689-3978"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Scott J. Myers","raw_affiliation_strings":["Department of Pharmacology, University of Washington, Seattle, WA 98195, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, University of Washington, Seattle, WA 98195, USA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087848665","display_name":"Jian Fu","orcid":"https://orcid.org/0000-0002-5399-7831","observed_orcids":["https://orcid.org/0000-0002-5399-7831"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jian Fu","raw_affiliation_strings":["Department of Pharmacology, University of Washington, Seattle, WA 98195, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, University of Washington, Seattle, WA 98195, USA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055452342","display_name":"Susan M. Mockus","orcid":"https://orcid.org/0000-0002-1939-5132","observed_orcids":["https://orcid.org/0000-0002-1939-5132"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan M. Mockus","raw_affiliation_strings":["Department of Pharmacology, University of Washington, Seattle, WA 98195, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, University of Washington, Seattle, WA 98195, USA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002307585","display_name":"Todd Scheuer","orcid":"https://orcid.org/0000-0003-3655-0816","observed_orcids":["https://orcid.org/0000-0003-3655-0816"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Todd Scheuer","raw_affiliation_strings":["Department of Pharmacology, University of Washington, Seattle, WA 98195, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, University of Washington, Seattle, WA 98195, USA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078941732","display_name":"William A. Catterall","orcid":"https://orcid.org/0000-0001-5509-3580","observed_orcids":["https://orcid.org/0000-0001-5509-3580"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"William A. Catterall","raw_affiliation_strings":["Department of Pharmacology, University of Washington, Seattle, WA 98195, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, University of Washington, Seattle, WA 98195, USA","institution_ids":["https://openalex.org/I201448701"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5078941732"],"corresponding_institution_ids":["https://openalex.org/I201448701"],"apc_list":{"value":3450,"currency":"USD","value_usd":3450},"apc_paid":null,"fwci":1.7576,"has_fulltext":false,"cited_by_count":87,"citation_normalized_percentile":{"value":0.83450231,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"28","issue":"1","first_page":"1","last_page":"17"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.6240000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.6240000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.3345000147819519,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.02019999921321869,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/snare-proteins","display_name":"SNARE proteins","score":0.7710000276565552},{"id":"https://openalex.org/keywords/n-type-calcium-channels","display_name":"N-type calcium channels","score":0.6869999766349792},{"id":"https://openalex.org/keywords/p-q-type-calcium-channels","display_name":"P/Q-type calcium channels","score":0.9739999771118164},{"id":"https://openalex.org/keywords/syntaxin-1a","display_name":"syntaxin 1A","score":0.902999997138977},{"id":"https://openalex.org/keywords/snap-25","display_name":"SNAP-25","score":1.0},{"id":"https://openalex.org/keywords/pkc-phosphorylation","display_name":"PKC phosphorylation","score":0.8970000147819519},{"id":"https://openalex.org/keywords/camkii-phosphorylation","display_name":"CaMKII phosphorylation","score":0.9990000128746033},{"id":"https://openalex.org/keywords/n-type-calcium-current","display_name":"N-type calcium current","score":0.996999979019165},{"id":"https://openalex.org/keywords/neurotransmitter-release","display_name":"neurotransmitter release","score":0.7269999980926514},{"id":"https://openalex.org/keywords/channel-modulation","display_name":"channel modulation","score":0.6100000143051147},{"id":"https://openalex.org/keywords/chimeric-channels","display_name":"chimeric channels","score":0.7379999756813049}],"concepts":[{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.8335450887680054},{"id":"https://openalex.org/C2778256703","wikidata":"https://www.wikidata.org/wiki/Q390407","display_name":"Syntaxin","level":4,"score":0.8119168877601624},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7059103846549988},{"id":"https://openalex.org/C195794163","wikidata":"https://www.wikidata.org/wiki/Q420877","display_name":"Protein kinase C","level":3,"score":0.6657824516296387},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5852640867233276},{"id":"https://openalex.org/C79061702","wikidata":"https://www.wikidata.org/wiki/Q18031772","display_name":"Syntaxin 3","level":5,"score":0.5678996443748474},{"id":"https://openalex.org/C53728453","wikidata":"https://www.wikidata.org/wiki/Q18031771","display_name":"STX1A","level":5,"score":0.5252392292022705},{"id":"https://openalex.org/C87325107","wikidata":"https://www.wikidata.org/wiki/Q7251493","display_name":"Protein phosphorylation","level":4,"score":0.4383273124694824},{"id":"https://openalex.org/C97029542","wikidata":"https://www.wikidata.org/wiki/Q281417","display_name":"Protein kinase A","level":3,"score":0.2869899272918701},{"id":"https://openalex.org/C144647389","wikidata":"https://www.wikidata.org/wiki/Q423042","display_name":"Membrane protein","level":3,"score":0.2415633201599121},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2290956676006317},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.0720071792602539}],"mesh":[{"descriptor_ui":"D000954","descriptor_name":"Antigens, Surface","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002490","descriptor_name":"Central Nervous System","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009419","descriptor_name":"Nerve Tissue Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009435","descriptor_name":"Synaptic Transmission","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D010766","descriptor_name":"Phosphorylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D011493","descriptor_name":"Protein Kinase C","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011993","descriptor_name":"Recombinant Fusion Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D013569","descriptor_name":"Synapses","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015220","descriptor_name":"Calcium Channels","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015220","descriptor_name":"Calcium Channels","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D017871","descriptor_name":"Calcium-Calmodulin-Dependent Protein Kinases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020746","descriptor_name":"Calcium Channels, L-Type","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020746","descriptor_name":"Calcium Channels, L-Type","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020864","descriptor_name":"Calcium Channels, N-Type","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020864","descriptor_name":"Calcium Channels, N-Type","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D033921","descriptor_name":"Vesicular Transport Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D050600","descriptor_name":"SNARE Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050825","descriptor_name":"Synaptosomal-Associated Protein 25","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050827","descriptor_name":"Syntaxin 1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054732","descriptor_name":"Calcium-Calmodulin-Dependent Protein Kinase Type 2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.mcn.2004.08.019","doi":"https://doi.org/10.1016/j.mcn.2004.08.019","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.mcn.2004.08.019","pdf_url":null,"source":{"id":"https://openalex.org/S47891569","display_name":"Molecular and Cellular Neuroscience","issn_l":"1044-7431","issn":["1044-7431","1095-9327"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Cellular Neuroscience","raw_type":"journal-article"},{"id":"pmid:15607937","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15607937","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and cellular neurosciences","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2751705235","display_name":"MOLECULAR BASIS OF CALCIUM CHANNEL/SNARE INTERACTION","funder_award_id":"F32NS011030","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G511977638","display_name":null,"funder_award_id":"T32NS0073322","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G5825393552","display_name":"Molecular Properties of Voltage-Sensitive Calcium Channels","funder_award_id":"R01NS022625","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"}],"funders":[{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":74,"referenced_works":["https://openalex.org/W138403972","https://openalex.org/W1481032119","https://openalex.org/W1490238549","https://openalex.org/W1498023566","https://openalex.org/W1511107734","https://openalex.org/W1518547852","https://openalex.org/W1526580466","https://openalex.org/W1601354097","https://openalex.org/W1602015813","https://openalex.org/W1606260021","https://openalex.org/W1639584526","https://openalex.org/W1733355263","https://openalex.org/W1822252127","https://openalex.org/W1912391091","https://openalex.org/W1940205808","https://openalex.org/W1966364658","https://openalex.org/W1969308562","https://openalex.org/W1971844027","https://openalex.org/W1978390881","https://openalex.org/W1979444121","https://openalex.org/W1979615726","https://openalex.org/W1980852615","https://openalex.org/W1982474924","https://openalex.org/W1988007470","https://openalex.org/W1988691994","https://openalex.org/W1990220309","https://openalex.org/W1997917368","https://openalex.org/W1999196432","https://openalex.org/W2000400738","https://openalex.org/W2012093804","https://openalex.org/W2015651475","https://openalex.org/W2018398859","https://openalex.org/W2018461674","https://openalex.org/W2019365444","https://openalex.org/W2021141924","https://openalex.org/W2031071883","https://openalex.org/W2032125422","https://openalex.org/W2035999317","https://openalex.org/W2042048113","https://openalex.org/W2053557358","https://openalex.org/W2053559739","https://openalex.org/W2056293200","https://openalex.org/W2057012057","https://openalex.org/W2058496293","https://openalex.org/W2058934405","https://openalex.org/W2060913542","https://openalex.org/W2062189135","https://openalex.org/W2062933575","https://openalex.org/W2064123037","https://openalex.org/W2065398045","https://openalex.org/W2066953895","https://openalex.org/W2067935544","https://openalex.org/W2068064646","https://openalex.org/W2070555996","https://openalex.org/W2070566940","https://openalex.org/W2077451533","https://openalex.org/W2084814544","https://openalex.org/W2085731308","https://openalex.org/W2089105518","https://openalex.org/W2090662268","https://openalex.org/W2109578053","https://openalex.org/W2110724392","https://openalex.org/W2112520390","https://openalex.org/W2125575826","https://openalex.org/W2136956832","https://openalex.org/W2142122391","https://openalex.org/W2143349524","https://openalex.org/W2151358879","https://openalex.org/W2155805035","https://openalex.org/W2163615816","https://openalex.org/W2327883130","https://openalex.org/W2432418695","https://openalex.org/W2912991414","https://openalex.org/W4252866398"],"related_works":["https://openalex.org/W1940205808","https://openalex.org/W176427177","https://openalex.org/W2037555898","https://openalex.org/W1601354097","https://openalex.org/W2030034627","https://openalex.org/W1994370876","https://openalex.org/W4239896616","https://openalex.org/W1997124286","https://openalex.org/W7064893170","https://openalex.org/W4248991932"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":10}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}