{"id":"https://openalex.org/W2094455488","doi":"https://doi.org/10.1016/j.ijid.2009.08.014","title":"Rotavirus disease burden, Nicaragua 2001\u20132005: defining the potential impact of a rotavirus vaccination program","display_name":"Rotavirus disease burden, Nicaragua 2001\u20132005: defining the potential impact of a rotavirus vaccination program","publication_year":2009,"publication_date":"2009-12-23","ids":{"openalex":"https://openalex.org/W2094455488","doi":"https://doi.org/10.1016/j.ijid.2009.08.014","mag":"2094455488","pmid":"https://pubmed.ncbi.nlm.nih.gov/20022778"},"language":"en","primary_location":{"id":"doi:10.1016/j.ijid.2009.08.014","doi":"https://doi.org/10.1016/j.ijid.2009.08.014","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ijid.2009.08.014","pdf_url":null,"source":{"id":"https://openalex.org/S35071406","display_name":"International Journal of Infectious Diseases","issn_l":"1201-9712","issn":["1201-9712","1878-3511"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Infectious Diseases","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.ijid.2009.08.014","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077277390","display_name":"Juan Jos\u00e9 Amador","orcid":"https://orcid.org/0000-0003-4538-6368","observed_orcids":["https://orcid.org/0000-0003-4538-6368"]},"institutions":[{"id":"https://openalex.org/I4210099049","display_name":"Program for Appropriate Technology in Health","ror":"https://ror.org/0150cj610","country_code":"IN","type":"nonprofit","lineage":["https://openalex.org/I1304598786","https://openalex.org/I4210099049"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Juan Jos\u00e9 Amador","raw_affiliation_strings":["Program for Appropriate Technology in Health, Managua, Nicaragua"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Program for Appropriate Technology in Health, Managua, Nicaragua","institution_ids":["https://openalex.org/I4210099049"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078428026","display_name":"Joshua Vasquez","orcid":"https://orcid.org/0000-0002-7165-5739","observed_orcids":["https://orcid.org/0000-0002-7165-5739"]},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joshua Vasquez","raw_affiliation_strings":["Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Atlanta, GA 30333, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Atlanta, GA 30333, USA","institution_ids":["https://openalex.org/I1289490764"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Maribel Orozco","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210133564","display_name":"Ministerio de Salud","ror":"https://ror.org/03c09x508","country_code":"NI","type":"government","lineage":["https://openalex.org/I4210133564"]}],"countries":["NI"],"is_corresponding":false,"raw_author_name":"Maribel Orozco","raw_affiliation_strings":["Ministerio de Salud, Managua, Nicaragua"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ministerio de Salud, Managua, Nicaragua","institution_ids":["https://openalex.org/I4210133564"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103530046","display_name":"Cristina Candal Pedreira","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210089393","display_name":"World Health Organization Regional Office for the Americas","ror":"https://ror.org/008kev776","country_code":"US","type":"government","lineage":["https://openalex.org/I4210089393","https://openalex.org/I4210105654"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cristina Pedreira","raw_affiliation_strings":["PanAmerican Health Organization, Managua, Nicaragua"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"PanAmerican Health Organization, Managua, Nicaragua","institution_ids":["https://openalex.org/I4210089393"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054027733","display_name":"Omar Malespin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210133564","display_name":"Ministerio de Salud","ror":"https://ror.org/03c09x508","country_code":"NI","type":"government","lineage":["https://openalex.org/I4210133564"]}],"countries":["NI"],"is_corresponding":false,"raw_author_name":"Omar Malespin","raw_affiliation_strings":["Ministerio de Salud, Managua, Nicaragua"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ministerio de Salud, Managua, Nicaragua","institution_ids":["https://openalex.org/I4210133564"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108122280","display_name":"L\u00facia Helena de Oliveira","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210089393","display_name":"World Health Organization Regional Office for the Americas","ror":"https://ror.org/008kev776","country_code":"US","type":"government","lineage":["https://openalex.org/I4210089393","https://openalex.org/I4210105654"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lucia Helena De Oliveira","raw_affiliation_strings":["PanAmerican Health Organization, Washington DC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"PanAmerican Health Organization, Washington DC, USA","institution_ids":["https://openalex.org/I4210089393"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061848201","display_name":"Jacqueline E. Tate","orcid":"https://orcid.org/0000-0002-8114-6196","observed_orcids":["https://orcid.org/0000-0002-8114-6196"]},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jacqueline Tate","raw_affiliation_strings":["Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Atlanta, GA 30333, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Atlanta, GA 30333, USA","institution_ids":["https://openalex.org/I1289490764"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054966986","display_name":"Umesh D. Parashar","orcid":"https://orcid.org/0000-0002-9684-9425","observed_orcids":["https://orcid.org/0000-0002-9684-9425"]},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Umesh Parashar","raw_affiliation_strings":["Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Atlanta, GA 30333, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Atlanta, GA 30333, USA","institution_ids":["https://openalex.org/I1289490764"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101999366","display_name":"Manish M. Patel","orcid":"https://orcid.org/0000-0001-8949-6548","observed_orcids":["https://orcid.org/0000-0001-8949-6548"]},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Manish Patel","raw_affiliation_strings":["Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Atlanta, GA 30333, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Atlanta, GA 30333, USA","institution_ids":["https://openalex.org/I1289490764"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5101999366"],"corresponding_institution_ids":["https://openalex.org/I1289490764"],"apc_list":{"value":2900,"currency":"USD","value_usd":2900},"apc_paid":{"value":2900,"currency":"USD","value_usd":2900},"fwci":2.0605,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.85842476,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"14","issue":"7","first_page":"e592","last_page":"e595"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10976","display_name":"Viral gastroenteritis research and epidemiology","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10976","display_name":"Viral gastroenteritis research and epidemiology","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10596","display_name":"Child Nutrition and Water Access","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10486","display_name":"Salmonella and Campylobacter epidemiology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rotavirus","display_name":"rotavirus","score":0.9259999990463257},{"id":"https://openalex.org/keywords/rotavirus-vaccination","display_name":"rotavirus vaccination","score":0.7160000205039978},{"id":"https://openalex.org/keywords/acute-gastroenteritis","display_name":"acute gastroenteritis","score":0.8309999704360962},{"id":"https://openalex.org/keywords/childhood-diarrhea","display_name":"childhood diarrhea","score":0.5120000243186951},{"id":"https://openalex.org/keywords/hospitalization","display_name":"hospitalization","score":0.7400000095367432},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.7960000038146973},{"id":"https://openalex.org/keywords/vaccine-impact-monitoring","display_name":"vaccine impact monitoring","score":0.6290000081062317},{"id":"https://openalex.org/keywords/seasonal-variation","display_name":"seasonal variation","score":0.6729999780654907},{"id":"https://openalex.org/keywords/nicaragua","display_name":"Nicaragua","score":0.609000027179718},{"id":"https://openalex.org/keywords/routine-immunization","display_name":"routine immunization","score":0.42100000381469727}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8764660358428955},{"id":"https://openalex.org/C2777227250","wikidata":"https://www.wikidata.org/wiki/Q4411598","display_name":"Rotavirus vaccine","level":4,"score":0.7738597393035889},{"id":"https://openalex.org/C2781367151","wikidata":"https://www.wikidata.org/wiki/Q164778","display_name":"Rotavirus","level":3,"score":0.7680831551551819},{"id":"https://openalex.org/C2779802037","wikidata":"https://www.wikidata.org/wiki/Q40878","display_name":"Diarrhea","level":2,"score":0.7387769222259521},{"id":"https://openalex.org/C2780664029","wikidata":"https://www.wikidata.org/wiki/Q5282120","display_name":"Disease burden","level":3,"score":0.6633938550949097},{"id":"https://openalex.org/C22070199","wikidata":"https://www.wikidata.org/wiki/Q192995","display_name":"Vaccination","level":2,"score":0.5959707498550415},{"id":"https://openalex.org/C3020448403","wikidata":"https://www.wikidata.org/wiki/Q5282120","display_name":"Burden of disease","level":3,"score":0.5689206123352051},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.5548136830329895},{"id":"https://openalex.org/C3020710733","wikidata":"https://www.wikidata.org/wiki/Q40878","display_name":"Diarrheal disease","level":3,"score":0.5254049897193909},{"id":"https://openalex.org/C2993801374","wikidata":"https://www.wikidata.org/wiki/Q156103","display_name":"Acute gastroenteritis","level":2,"score":0.5111420750617981},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.49457141757011414},{"id":"https://openalex.org/C2780801004","wikidata":"https://www.wikidata.org/wiki/Q1415366","display_name":"Immunization","level":3,"score":0.4739922285079956},{"id":"https://openalex.org/C2909654208","wikidata":"https://www.wikidata.org/wiki/Q1415366","display_name":"Immunization program","level":4,"score":0.4576941132545471},{"id":"https://openalex.org/C2909321700","wikidata":"https://www.wikidata.org/wiki/Q181600","display_name":"Outpatient visits","level":3,"score":0.442806601524353},{"id":"https://openalex.org/C3019834005","wikidata":"https://www.wikidata.org/wiki/Q156103","display_name":"Acute diarrhea","level":3,"score":0.4396921396255493},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.39268726110458374},{"id":"https://openalex.org/C160735492","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Health care","level":2,"score":0.2902410626411438},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.14320439100265503},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.12358170747756958},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.08358970284461975},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.0},{"id":"https://openalex.org/C50522688","wikidata":"https://www.wikidata.org/wiki/Q189833","display_name":"Economic growth","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005759","descriptor_name":"Gastroenteritis","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D005759","descriptor_name":"Gastroenteritis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D005759","descriptor_name":"Gastroenteritis","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D005759","descriptor_name":"Gastroenteritis","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D006760","descriptor_name":"Hospitalization","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009527","descriptor_name":"Nicaragua","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D012400","descriptor_name":"Rotavirus Infections","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D012400","descriptor_name":"Rotavirus Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D012400","descriptor_name":"Rotavirus Infections","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D012400","descriptor_name":"Rotavirus Infections","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D014611","descriptor_name":"Vaccination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017589","descriptor_name":"Immunization Programs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D022243","descriptor_name":"Rotavirus Vaccines","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D022243","descriptor_name":"Rotavirus Vaccines","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.ijid.2009.08.014","doi":"https://doi.org/10.1016/j.ijid.2009.08.014","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ijid.2009.08.014","pdf_url":null,"source":{"id":"https://openalex.org/S35071406","display_name":"International Journal of Infectious Diseases","issn_l":"1201-9712","issn":["1201-9712","1878-3511"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Infectious Diseases","raw_type":"journal-article"},{"id":"pmid:20022778","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20022778","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.ijid.2009.08.014","doi":"https://doi.org/10.1016/j.ijid.2009.08.014","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ijid.2009.08.014","pdf_url":null,"source":{"id":"https://openalex.org/S35071406","display_name":"International Journal of Infectious Diseases","issn_l":"1201-9712","issn":["1201-9712","1878-3511"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Infectious Diseases","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"},{"score":0.40450000762939453,"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W1569826234","https://openalex.org/W2002920916","https://openalex.org/W2006763045","https://openalex.org/W2016015591","https://openalex.org/W2023514298","https://openalex.org/W2042685123","https://openalex.org/W2100178369","https://openalex.org/W2101154874","https://openalex.org/W2104362710","https://openalex.org/W2132933841","https://openalex.org/W2143233237","https://openalex.org/W2170749337","https://openalex.org/W3165064679"],"related_works":["https://openalex.org/W2135924606","https://openalex.org/W4406353215","https://openalex.org/W2804987883","https://openalex.org/W7070586807","https://openalex.org/W7043155158","https://openalex.org/W2774297651","https://openalex.org/W2054063508","https://openalex.org/W2085784554","https://openalex.org/W2301009644","https://openalex.org/W2625476227"],"abstract_inverted_index":{"BACKGROUND:":[0],"In":[1],"October":[2],"2006,":[3],"a":[4,175],"rotavirus":[5,181],"vaccine":[6,29,37,64,156],"was":[7,117],"introduced":[8],"in":[9,24,55,71,80,86,118,130,163],"Nicaragua":[10,25],"for":[11,44,147],"routine":[12],"immunization":[13],"of":[14,111,122,159,165,178],"all":[15],"children.":[16],"We":[17,40],"document":[18],"the":[19,28,112],"baseline":[20],"diarrheal":[21],"disease":[22,150],"burden":[23,116,151],"prior":[26],"to":[27,31,35,63],"program":[30],"facilitate":[32],"future":[33],"studies":[34],"measure":[36],"impact.":[38],"METHODS:":[39],"analyzed":[41],"national":[42],"data":[43,138],"2001-2005":[45],"on":[46,140],"total":[47,113],"acute":[48,114,131,142],"gastroenteritis":[49,115,132,143],"healthcare":[50],"visits,":[51,96],"hospitalizations,":[52,98],"and":[53,84,99,134,152],"mortality":[54],"Nicaraguan":[56,73],"children":[57,74,119,169],"aged":[58,170],"<5":[59],"years.":[60],"RESULTS:":[61],"Prior":[62],"introduction,":[65],"by":[66],"age":[67],"5":[68],"years,":[69,172],"one":[70,79,85],"four":[72],"required":[75],"an":[76],"outpatient":[77,95],"consultation,":[78],"34":[81],"were":[82,128],"hospitalized,":[83],"2487":[87],"died":[88],"from":[89,180],"rotavirus-associated":[90],"diarrhea,":[91,166],"representing":[92],"approximately":[93],"41,122":[94],"4460":[97],"60":[100],"deaths":[101],"per":[102],"year":[103,121],"that":[104],"are":[105],"preventable":[106],"through":[107],"vaccination.":[108,182],"Almost":[109],"half":[110],"<1":[120],"age.":[123],"Two":[124],"distinct":[125],"seasonal":[126],"peaks":[127,162],"noted":[129],"hospitalizations":[133],"deaths.":[135],"CONCLUSIONS:":[136],"Existing":[137],"sources":[139],"all-cause":[141],"could":[144],"be":[145,174],"useful":[146,176],"establishing":[148],"diarrhea":[149],"monitoring":[153],"trends":[154],"after":[155],"introduction.":[157],"Blunting":[158],"winter":[160],"season":[161],"rates":[164],"particularly":[167],"among":[168],"<1-2":[171],"would":[173],"indicator":[177],"impact":[179]},"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}