{"id":"https://openalex.org/W2094432035","doi":"https://doi.org/10.4103/0255-0857.150879","title":"Early detection of multi-drug resistance and common mutations in Mycobacterium tuberculosis isolates from Delhi using GenoType MTBDRplus assay","display_name":"Early detection of multi-drug resistance and common mutations in Mycobacterium tuberculosis isolates from Delhi using GenoType MTBDRplus assay","publication_year":2015,"publication_date":"2015-02-01","ids":{"openalex":"https://openalex.org/W2094432035","doi":"https://doi.org/10.4103/0255-0857.150879","mag":"2094432035","pmid":"https://pubmed.ncbi.nlm.nih.gov/25657156"},"language":"en","primary_location":{"id":"doi:10.4103/0255-0857.150879","doi":"https://doi.org/10.4103/0255-0857.150879","is_oa":true,"landing_page_url":"https://doi.org/10.4103/0255-0857.150879","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0255085721000724/pdf","source":{"id":"https://openalex.org/S131141226","display_name":"Indian Journal of Medical Microbiology","issn_l":"0255-0857","issn":["0255-0857","1998-3646"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian Journal of Medical Microbiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.sciencedirect.com/science/article/pii/S0255085721000724/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033633035","display_name":"Ritu Singhal","orcid":"https://orcid.org/0000-0002-2166-5760","observed_orcids":["https://orcid.org/0000-0002-2166-5760"]},"institutions":[{"id":"https://openalex.org/I4210094819","display_name":"LRS Institute of Tuberculosis and Respiratory Diseases","ror":"https://ror.org/00j49rw24","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210094819","https://openalex.org/I4210148677"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"R Singhal","raw_affiliation_strings":["Department of Microbiology (RS, VPM, JA, NS, MB, AV), Department of TB and Chest (RS), National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India","Department of Microbiology, National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology (RS, VPM, JA, NS, MB, AV), Department of TB and Chest (RS), National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India","institution_ids":["https://openalex.org/I4210094819"]},{"raw_affiliation_string":"Department of Microbiology, National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India","institution_ids":["https://openalex.org/I4210094819"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067705895","display_name":"Vithal Prasad Myneedu","orcid":"https://orcid.org/0000-0003-4145-8678","observed_orcids":["https://orcid.org/0000-0003-4145-8678"]},"institutions":[{"id":"https://openalex.org/I4210094819","display_name":"LRS Institute of Tuberculosis and Respiratory Diseases","ror":"https://ror.org/00j49rw24","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210094819","https://openalex.org/I4210148677"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"VP Myneedu","raw_affiliation_strings":["Department of Microbiology, National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India","institution_ids":["https://openalex.org/I4210094819"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101690980","display_name":"Jyoti Kumar Arora","orcid":"https://orcid.org/0000-0002-9957-4922","observed_orcids":["https://orcid.org/0000-0002-9957-4922"]},"institutions":[{"id":"https://openalex.org/I4210094819","display_name":"LRS Institute of Tuberculosis and Respiratory Diseases","ror":"https://ror.org/00j49rw24","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210094819","https://openalex.org/I4210148677"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"J Arora","raw_affiliation_strings":["Department of Microbiology (RS, VPM, JA, NS, MB, AV), Department of TB and Chest (RS), National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India","Department of Microbiology, National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology (RS, VPM, JA, NS, MB, AV), Department of TB and Chest (RS), National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India","institution_ids":["https://openalex.org/I4210094819"]},{"raw_affiliation_string":"Department of Microbiology, National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India","institution_ids":["https://openalex.org/I4210094819"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079326990","display_name":"Namit Kant Singh","orcid":"https://orcid.org/0000-0002-4290-6930","observed_orcids":["https://orcid.org/0000-0002-4290-6930"]},"institutions":[{"id":"https://openalex.org/I4210094819","display_name":"LRS Institute of Tuberculosis and Respiratory Diseases","ror":"https://ror.org/00j49rw24","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210094819","https://openalex.org/I4210148677"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"N Singh","raw_affiliation_strings":["Department of Microbiology (RS, VPM, JA, NS, MB, AV), Department of TB and Chest (RS), National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India","Department of Microbiology, National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology (RS, VPM, JA, NS, MB, AV), Department of TB and Chest (RS), National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India","institution_ids":["https://openalex.org/I4210094819"]},{"raw_affiliation_string":"Department of Microbiology, National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India","institution_ids":["https://openalex.org/I4210094819"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066168613","display_name":"Manpreet Bhalla","orcid":"https://orcid.org/0000-0002-8128-402X","observed_orcids":["https://orcid.org/0000-0002-8128-402X"]},"institutions":[{"id":"https://openalex.org/I4210094819","display_name":"LRS Institute of Tuberculosis and Respiratory Diseases","ror":"https://ror.org/00j49rw24","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210094819","https://openalex.org/I4210148677"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"M Bhalla","raw_affiliation_strings":["Department of Microbiology (RS, VPM, JA, NS, MB, AV), Department of TB and Chest (RS), National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India","Department of Microbiology, National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology (RS, VPM, JA, NS, MB, AV), Department of TB and Chest (RS), National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India","institution_ids":["https://openalex.org/I4210094819"]},{"raw_affiliation_string":"Department of Microbiology, National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India","institution_ids":["https://openalex.org/I4210094819"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016416693","display_name":"Ajoy Kumar Verma","orcid":"https://orcid.org/0000-0002-9466-8049","observed_orcids":["https://orcid.org/0000-0002-9466-8049"]},"institutions":[{"id":"https://openalex.org/I4210094819","display_name":"LRS Institute of Tuberculosis and Respiratory Diseases","ror":"https://ror.org/00j49rw24","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210094819","https://openalex.org/I4210148677"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"A Verma","raw_affiliation_strings":["Department of Microbiology (RS, VPM, JA, NS, MB, AV), Department of TB and Chest (RS), National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India","Department of Microbiology, National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology (RS, VPM, JA, NS, MB, AV), Department of TB and Chest (RS), National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India","institution_ids":["https://openalex.org/I4210094819"]},{"raw_affiliation_string":"Department of Microbiology, National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India","institution_ids":["https://openalex.org/I4210094819"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031032220","display_name":"Rajiv Sarin","orcid":"https://orcid.org/0000-0002-6405-8282","observed_orcids":["https://orcid.org/0000-0002-6405-8282"]},"institutions":[{"id":"https://openalex.org/I4210094819","display_name":"LRS Institute of Tuberculosis and Respiratory Diseases","ror":"https://ror.org/00j49rw24","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210094819","https://openalex.org/I4210148677"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"R Sarin","raw_affiliation_strings":["Department of Microbiology (RS, VPM, JA, NS, MB, AV), Department of TB and Chest (RS), National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India","Department of TB and Chest, National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology (RS, VPM, JA, NS, MB, AV), Department of TB and Chest (RS), National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India","institution_ids":["https://openalex.org/I4210094819"]},{"raw_affiliation_string":"Department of TB and Chest, National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India","institution_ids":["https://openalex.org/I4210094819"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5067705895"],"corresponding_institution_ids":["https://openalex.org/I4210094819"],"apc_list":{"value":2210,"currency":"USD","value_usd":2210},"apc_paid":{"value":2210,"currency":"USD","value_usd":2210},"fwci":2.9605,"has_fulltext":true,"cited_by_count":32,"citation_normalized_percentile":{"value":0.90787955,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"33","issue":null,"first_page":"S46","last_page":"S52"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11381","display_name":"Infectious Diseases and Tuberculosis","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11316","display_name":"Mycobacterium research and diagnosis","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multidrug-resistant-tuberculosis","display_name":"multidrug-resistant tuberculosis","score":0.9490000009536743},{"id":"https://openalex.org/keywords/mycobacterium-tuberculosis","display_name":"Mycobacterium tuberculosis","score":0.9509999752044678},{"id":"https://openalex.org/keywords/rpob-mutations","display_name":"rpoB mutations","score":0.9300000071525574},{"id":"https://openalex.org/keywords/katg-mutations","display_name":"katG mutations","score":0.8109999895095825},{"id":"https://openalex.org/keywords/inha-mutations","display_name":"inhA mutations","score":0.9990000128746033},{"id":"https://openalex.org/keywords/rifampicin-resistance","display_name":"rifampicin resistance","score":0.9869999885559082},{"id":"https://openalex.org/keywords/isoniazid-resistance","display_name":"isoniazid resistance","score":0.9990000128746033},{"id":"https://openalex.org/keywords/mdr-tb-prevalence","display_name":"MDR-TB prevalence","score":0.7670000195503235},{"id":"https://openalex.org/keywords/delhi","display_name":"Delhi","score":0.6909999847412109},{"id":"https://openalex.org/keywords/rapid-molecular-detection","display_name":"rapid molecular detection","score":0.5649999976158142},{"id":"https://openalex.org/keywords/laboratory-turnaround-time","display_name":"laboratory turnaround time","score":0.5180000066757202}],"concepts":[{"id":"https://openalex.org/C2780687663","wikidata":"https://www.wikidata.org/wiki/Q18027924","display_name":"INHA","level":4,"score":0.8919610381126404},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.7775083184242249},{"id":"https://openalex.org/C2776967927","wikidata":"https://www.wikidata.org/wiki/Q423169","display_name":"Isoniazid","level":3,"score":0.7283045053482056},{"id":"https://openalex.org/C2778340795","wikidata":"https://www.wikidata.org/wiki/Q24782946","display_name":"rpoB","level":4,"score":0.6745234131813049},{"id":"https://openalex.org/C2778607973","wikidata":"https://www.wikidata.org/wiki/Q422652","display_name":"Rifampicin","level":3,"score":0.6168032884597778},{"id":"https://openalex.org/C2777975735","wikidata":"https://www.wikidata.org/wiki/Q130971","display_name":"Mycobacterium tuberculosis","level":3,"score":0.6006093621253967},{"id":"https://openalex.org/C133936738","wikidata":"https://www.wikidata.org/wiki/Q643839","display_name":"Multiple drug resistance","level":3,"score":0.5642757415771484},{"id":"https://openalex.org/C2781069245","wikidata":"https://www.wikidata.org/wiki/Q12204","display_name":"Tuberculosis","level":2,"score":0.5634881854057312},{"id":"https://openalex.org/C114851261","wikidata":"https://www.wikidata.org/wiki/Q12147416","display_name":"Drug resistance","level":2,"score":0.5235059857368469},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5179673433303833},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5160560011863708},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4158777892589569},{"id":"https://openalex.org/C42972112","wikidata":"https://www.wikidata.org/wiki/Q170201","display_name":"Veterinary medicine","level":1,"score":0.40270841121673584},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.34290820360183716},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.23761671781539917},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.20140138268470764},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1738373041152954},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.06874755024909973}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000995","descriptor_name":"Antitubercular Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004252","descriptor_name":"DNA Mutational Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007194","descriptor_name":"India","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008826","descriptor_name":"Microbial Sensitivity Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008853","descriptor_name":"Microscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009169","descriptor_name":"Mycobacterium tuberculosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D009169","descriptor_name":"Mycobacterium tuberculosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D013183","descriptor_name":"Sputum","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D018088","descriptor_name":"Tuberculosis, Multidrug-Resistant","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D018088","descriptor_name":"Tuberculosis, Multidrug-Resistant","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D018088","descriptor_name":"Tuberculosis, Multidrug-Resistant","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D042241","descriptor_name":"Early Diagnosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060005","descriptor_name":"Genotyping Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.4103/0255-0857.150879","doi":"https://doi.org/10.4103/0255-0857.150879","is_oa":true,"landing_page_url":"https://doi.org/10.4103/0255-0857.150879","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0255085721000724/pdf","source":{"id":"https://openalex.org/S131141226","display_name":"Indian Journal of Medical Microbiology","issn_l":"0255-0857","issn":["0255-0857","1998-3646"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian Journal of Medical Microbiology","raw_type":"journal-article"},{"id":"pmid:25657156","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25657156","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian journal of medical microbiology","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:4417eda25bc04f9eade63d67fa2878d7","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/4417eda25bc04f9eade63d67fa2878d7","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Indian Journal of Medical Microbiology, Vol 33, Iss 5, Pp 46-52 (2015)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.4103/0255-0857.150879","doi":"https://doi.org/10.4103/0255-0857.150879","is_oa":true,"landing_page_url":"https://doi.org/10.4103/0255-0857.150879","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0255085721000724/pdf","source":{"id":"https://openalex.org/S131141226","display_name":"Indian Journal of Medical Microbiology","issn_l":"0255-0857","issn":["0255-0857","1998-3646"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian Journal of Medical Microbiology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9763000011444092,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320719","display_name":"Department of Science and Technology, Ministry of Science and Technology, India","ror":"https://ror.org/0101xrq71"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2094432035.pdf","grobid_xml":"https://content.openalex.org/works/W2094432035.grobid-xml"},"referenced_works_count":17,"referenced_works":["https://openalex.org/W1520768660","https://openalex.org/W1981976611","https://openalex.org/W2025035733","https://openalex.org/W2034168730","https://openalex.org/W2096555718","https://openalex.org/W2098719989","https://openalex.org/W2100138581","https://openalex.org/W2112138356","https://openalex.org/W2125179847","https://openalex.org/W2139306579","https://openalex.org/W2150843895","https://openalex.org/W2154491836","https://openalex.org/W2163941297","https://openalex.org/W2164876670","https://openalex.org/W2168191366","https://openalex.org/W2168848141","https://openalex.org/W4248545381"],"related_works":["https://openalex.org/W2167793087","https://openalex.org/W2619335691","https://openalex.org/W2052433541","https://openalex.org/W2107364530","https://openalex.org/W2019786530","https://openalex.org/W2015946426","https://openalex.org/W1992784747","https://openalex.org/W2662717356","https://openalex.org/W4200005225","https://openalex.org/W2903043698"],"abstract_inverted_index":{"PURPOSE:":[0],"There":[1],"is":[2,190],"scarcity":[3],"of":[4,7,46,71,108,175,197],"prevalence":[5],"data":[6,11],"multi-drug-resistant":[8],"tuberculosis":[9],"(MDR-TB)":[10],"and":[12,30,86,95,97,123,129,142,150,163,204,219,227],"common":[13,134,200],"mutations":[14,87,201,215],"responsible":[15],"in":[16,43,88,155,211],"North":[17],"India.":[18],"This":[19],"study":[20],"aimed":[21],"to":[22,51,59,119,160,177,208],"detect":[23],"MDR-TB":[24,26,111],"among":[25],"suspects":[27,42],"from":[28,54],"Delhi":[29,48],"mutation":[31,135],"patterns":[32],"using":[33],"GenoType":[34,76,188],"MTBDRplus":[35,77,189],"assay.":[36],"MATERIALS":[37],"AND":[38],"METHODS:":[39],"All":[40],"MDR":[41,115,156,217],"five":[44],"districts":[45,178],"New":[47],"were":[49,103,113,206],"referred":[50],"the":[52,89],"laboratory":[53,169],"1":[55],"st":[56,61],"October":[57],"2011":[58],"31":[60],"December":[62],"2012":[63],"as":[64,158],"per":[65],"criterion":[66,126],"defined":[67],"by":[68],"Programmatic":[69],"Management":[70],"Drug":[72],"Resistant":[73],"Tuberculosis":[74],"(PMDT).":[75],"assay":[78,193],"was":[79,117,139,145,184],"performed":[80],"on":[81,182],"2182":[82],"samples":[83,183],"or":[84],"cultures":[85],"rpoB":[90],"gene":[91],"for":[92,100,137,143,173,179,194,202,224],"rifampicin":[93],"(RIF)":[94],"katG":[96],"inhA":[98],"genes":[99],"isoniazid":[101],"(INH)":[102],"analyzed.":[104],"RESULTS:":[105],"A":[106],"total":[107],"366":[109],"(16.8%)":[110],"cases":[112],"diagnosed.":[114],"rate":[116],"found":[118],"be":[120],"32%,":[121],"16.6%":[122],"10.2%":[124],"during":[125],"A,":[127],"B":[128],"C":[130],"respectively.":[131,167],"The":[132,199],"most":[133],"detected":[136],"RIF":[138,161,203,226],"S531L":[140,149],"(59.0%)":[141],"INH":[144,164,205],"S315T1":[146,151],"(88.3%).":[147],"Mutations":[148],"occurred":[152],"significantly":[153,223],"higher":[154],"strains":[157,218,221],"compared":[159],"mono-resistant":[162,165,220],"strains,":[166],"Average":[168],"turn-around":[170],"time":[171],"(TAT)":[172],"dispatch":[174],"result":[176],"test":[180],"conducted":[181],"4.4":[185],"days.":[186],"CONCLUSION:":[187],"a":[191],"useful":[192],"rapid":[195],"detection":[196],"MDR-TB.":[198],"similar":[207],"those":[209],"seen":[210],"other":[212],"regions.":[213],"However,":[214],"determining":[216],"differed":[222],"both":[225],"INH.":[228]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":6}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}