{"id":"https://openalex.org/W2094046886","doi":"https://doi.org/10.1021/jf034573h","title":"Use of Recombinant Cyprosin in the Manufacture of Ewe's Milk Cheese","display_name":"Use of Recombinant Cyprosin in the Manufacture of Ewe's Milk Cheese","publication_year":2003,"publication_date":"2003-11-05","ids":{"openalex":"https://openalex.org/W2094046886","doi":"https://doi.org/10.1021/jf034573h","mag":"2094046886","pmid":"https://pubmed.ncbi.nlm.nih.gov/14640594"},"language":"en","primary_location":{"id":"doi:10.1021/jf034573h","doi":"https://doi.org/10.1021/jf034573h","is_oa":false,"landing_page_url":"https://doi.org/10.1021/jf034573h","pdf_url":null,"source":{"id":"https://openalex.org/S134644764","display_name":"Journal of Agricultural and Food Chemistry","issn_l":"0021-8561","issn":["0021-8561","1520-5118"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Agricultural and Food Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021872083","display_name":"JOS\u00c9 FERN\u00c1NDEZ\u2010SALGUERO","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I53110688","display_name":"University of C\u00f3rdoba","ror":"https://ror.org/05yc77b46","country_code":"ES","type":"education","lineage":["https://openalex.org/I53110688"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Jos\u00e9 Fern\u00e1ndez-Salguero","raw_affiliation_strings":["Departamento de Bromatolog\u00eda y Tecnolog\u00eda de los Alimentos, Campus de Rabanales, Edificio C-1, Universidad de C\u00f3rdoba, E-14014 C\u00f3rdoba, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Bromatolog\u00eda y Tecnolog\u00eda de los Alimentos, Campus de Rabanales, Edificio C-1, Universidad de C\u00f3rdoba, E-14014 C\u00f3rdoba, Spain","institution_ids":["https://openalex.org/I53110688"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111899004","display_name":"Francisco Prados","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I53110688","display_name":"University of C\u00f3rdoba","ror":"https://ror.org/05yc77b46","country_code":"ES","type":"education","lineage":["https://openalex.org/I53110688"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Francisco Prados","raw_affiliation_strings":["Departamento de Bromatolog\u00eda y Tecnolog\u00eda de los Alimentos, Campus de Rabanales, Edificio C-1, Universidad de C\u00f3rdoba, E-14014 C\u00f3rdoba, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Bromatolog\u00eda y Tecnolog\u00eda de los Alimentos, Campus de Rabanales, Edificio C-1, Universidad de C\u00f3rdoba, E-14014 C\u00f3rdoba, Spain","institution_ids":["https://openalex.org/I53110688"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002475474","display_name":"Filomena Sousa Calixto","orcid":"https://orcid.org/0000-0003-0103-394X","observed_orcids":["https://orcid.org/0000-0003-0103-394X"]},"institutions":[{"id":"https://openalex.org/I53110688","display_name":"University of C\u00f3rdoba","ror":"https://ror.org/05yc77b46","country_code":"ES","type":"education","lineage":["https://openalex.org/I53110688"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Filomena Calixto","raw_affiliation_strings":["Departamento de Bromatolog\u00eda y Tecnolog\u00eda de los Alimentos, Campus de Rabanales, Edificio C-1, Universidad de C\u00f3rdoba, E-14014 C\u00f3rdoba, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Bromatolog\u00eda y Tecnolog\u00eda de los Alimentos, Campus de Rabanales, Edificio C-1, Universidad de C\u00f3rdoba, E-14014 C\u00f3rdoba, Spain","institution_ids":["https://openalex.org/I53110688"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114254913","display_name":"Montserrat Vioque","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I53110688","display_name":"University of C\u00f3rdoba","ror":"https://ror.org/05yc77b46","country_code":"ES","type":"education","lineage":["https://openalex.org/I53110688"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Montserrat Vioque","raw_affiliation_strings":["Departamento de Bromatolog\u00eda y Tecnolog\u00eda de los Alimentos, Campus de Rabanales, Edificio C-1, Universidad de C\u00f3rdoba, E-14014 C\u00f3rdoba, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Bromatolog\u00eda y Tecnolog\u00eda de los Alimentos, Campus de Rabanales, Edificio C-1, Universidad de C\u00f3rdoba, E-14014 C\u00f3rdoba, Spain","institution_ids":["https://openalex.org/I53110688"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041172102","display_name":"Pedro Sampaio","orcid":"https://orcid.org/0000-0003-2917-4904","observed_orcids":["https://orcid.org/0000-0003-2917-4904"]},"institutions":[{"id":"https://openalex.org/I53110688","display_name":"University of C\u00f3rdoba","ror":"https://ror.org/05yc77b46","country_code":"ES","type":"education","lineage":["https://openalex.org/I53110688"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Pedro Sampaio","raw_affiliation_strings":["Departamento de Bromatolog\u00eda y Tecnolog\u00eda de los Alimentos, Campus de Rabanales, Edificio C-1, Universidad de C\u00f3rdoba, E-14014 C\u00f3rdoba, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Bromatolog\u00eda y Tecnolog\u00eda de los Alimentos, Campus de Rabanales, Edificio C-1, Universidad de C\u00f3rdoba, E-14014 C\u00f3rdoba, Spain","institution_ids":["https://openalex.org/I53110688"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088708881","display_name":"Luis Coronas Tejada","orcid":"https://orcid.org/0000-0002-5830-0597","observed_orcids":["https://orcid.org/0000-0002-5830-0597"]},"institutions":[{"id":"https://openalex.org/I53110688","display_name":"University of C\u00f3rdoba","ror":"https://ror.org/05yc77b46","country_code":"ES","type":"education","lineage":["https://openalex.org/I53110688"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Luis Tejada","raw_affiliation_strings":["Departamento de Bromatolog\u00eda y Tecnolog\u00eda de los Alimentos, Campus de Rabanales, Edificio C-1, Universidad de C\u00f3rdoba, E-14014 C\u00f3rdoba, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Bromatolog\u00eda y Tecnolog\u00eda de los Alimentos, Campus de Rabanales, Edificio C-1, Universidad de C\u00f3rdoba, E-14014 C\u00f3rdoba, Spain","institution_ids":["https://openalex.org/I53110688"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I53110688"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":0.5442,"has_fulltext":false,"cited_by_count":20,"citation_normalized_percentile":{"value":0.77284269,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"51","issue":"25","first_page":"7426","last_page":"7430"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10411","display_name":"Proteins in Food Systems","score":0.29269999265670776,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10411","display_name":"Proteins in Food Systems","score":0.29269999265670776,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11617","display_name":"Enzyme Production and Characterization","score":0.23770000040531158,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14438","display_name":"Advanced Scientific Research Methods","score":0.15539999306201935,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cardoon","display_name":"Cynara cardunculus","score":0.8740000128746033},{"id":"https://openalex.org/keywords/ewe-s-milk-cheese","display_name":"ewe's milk cheese","score":0.765999972820282},{"id":"https://openalex.org/keywords/animal-rennet","display_name":"animal rennet","score":0.6690000295639038},{"id":"https://openalex.org/keywords/cheese-coagulants","display_name":"cheese coagulants","score":0.781000018119812},{"id":"https://openalex.org/keywords/cheese-ripening","display_name":"cheese ripening","score":0.8230000138282776},{"id":"https://openalex.org/keywords/proteolysis","display_name":"proteolysis","score":0.9869999885559082},{"id":"https://openalex.org/keywords/soluble-nitrogen","display_name":"soluble nitrogen","score":0.8029999732971191},{"id":"https://openalex.org/keywords/non-protein-nitrogen","display_name":"non-protein nitrogen","score":0.968999981880188},{"id":"https://openalex.org/keywords/cheese-microbiology","display_name":"cheese microbiology","score":0.5509999990463257},{"id":"https://openalex.org/keywords/microbial-counts","display_name":"microbial counts","score":0.3610000014305115}],"concepts":[{"id":"https://openalex.org/C2779219906","wikidata":"https://www.wikidata.org/wiki/Q326900","display_name":"Rennet","level":3,"score":0.9404388666152954},{"id":"https://openalex.org/C2776738293","wikidata":"https://www.wikidata.org/wiki/Q19070","display_name":"Cynara","level":2,"score":0.8830769062042236},{"id":"https://openalex.org/C172353545","wikidata":"https://www.wikidata.org/wiki/Q2121926","display_name":"Ripening","level":2,"score":0.8796462416648865},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.7945038080215454},{"id":"https://openalex.org/C2779389801","wikidata":"https://www.wikidata.org/wiki/Q2826073","display_name":"Cheese ripening","level":3,"score":0.672722578048706},{"id":"https://openalex.org/C2781307694","wikidata":"https://www.wikidata.org/wiki/Q33123","display_name":"Proteolysis","level":3,"score":0.6643731594085693},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5895587205886841},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.5372536182403564},{"id":"https://openalex.org/C2776477769","wikidata":"https://www.wikidata.org/wiki/Q1281188","display_name":"Cheesemaking","level":2,"score":0.47698360681533813},{"id":"https://openalex.org/C2778498626","wikidata":"https://www.wikidata.org/wiki/Q2736146","display_name":"Sheep milk","level":2,"score":0.45620134472846985},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2933477461338043},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.15951663255691528},{"id":"https://openalex.org/C2776142715","wikidata":"https://www.wikidata.org/wiki/Q193970","display_name":"Casein","level":2,"score":0.15146544575691223},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.13528671860694885},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.05953794717788696},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002611","descriptor_name":"Cheese","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005511","descriptor_name":"Food Handling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008892","descriptor_name":"Milk","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012085","descriptor_name":"Chymosin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012756","descriptor_name":"Sheep","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016282","descriptor_name":"Aspartic Acid Endopeptidases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D031942","descriptor_name":"Cynara","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1021/jf034573h","doi":"https://doi.org/10.1021/jf034573h","is_oa":false,"landing_page_url":"https://doi.org/10.1021/jf034573h","pdf_url":null,"source":{"id":"https://openalex.org/S134644764","display_name":"Journal of Agricultural and Food Chemistry","issn_l":"0021-8561","issn":["0021-8561","1520-5118"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Agricultural and Food Chemistry","raw_type":"journal-article"},{"id":"pmid:14640594","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14640594","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of agricultural and food chemistry","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Zero hunger","score":0.875,"id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320323424","display_name":"Universidade de Lisboa","ror":"https://ror.org/01c27hj86"},{"id":"https://openalex.org/F4320332163","display_name":"U.S. Food and Drug Administration","ror":"https://ror.org/034xvzb47"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1499321752","https://openalex.org/W1970391112","https://openalex.org/W1978677307","https://openalex.org/W2006074123","https://openalex.org/W2006423476","https://openalex.org/W2013110864","https://openalex.org/W2055086427","https://openalex.org/W2076692815","https://openalex.org/W2086512538","https://openalex.org/W2109581295","https://openalex.org/W2119990681","https://openalex.org/W2142685726","https://openalex.org/W2142798047","https://openalex.org/W3007374868"],"related_works":["https://openalex.org/W2079355742","https://openalex.org/W2148296712","https://openalex.org/W2126838854","https://openalex.org/W2009472189","https://openalex.org/W2095877803","https://openalex.org/W1979467152","https://openalex.org/W1970391112","https://openalex.org/W2091476105","https://openalex.org/W7148981841","https://openalex.org/W1994419637"],"abstract_inverted_index":{"A":[0],"recombinant":[1,61,98],"cyprosin":[2,62,99],"from":[3],"the":[4,40,65,80,87,91,119,130,138],"cardoon":[5],"(Cynara":[6],"cardunculus":[7],"L.)":[8],"was":[9,53,71,100],"assayed":[10],"and":[11,27,50,56],"compared":[12,107],"with":[13,83,97,108,113,148],"calf":[14],"rennet":[15],"in":[16,45,58,110,118,127,136,145],"batches":[17],"of":[18,33,43,69,79,89,94,129,151],"ewes'":[19],"milk":[20,120],"cheese":[21,59,81,95,124,146],"by":[22],"determining":[23],"different":[24],"chemical,":[25],"biochemical,":[26],"microbiological":[28],"parameters":[29],"over":[30],"4":[31],"months":[32],"ripening.":[34,154],"There":[35],"were":[36,125,143],"no":[37],"differences":[38,135],"between":[39],"two":[41],"types":[42,150],"coagulants":[44,152],"most":[46,128],"chemical":[47],"parameters,":[48],"a(w),":[49],"pH.":[51],"Proteolysis":[52],"more":[54],"marked":[55],"rapid":[57],"containing":[60],"as":[63,106],"coagulant,":[64],"soluble":[66],"nitrogen":[67,93],"content":[68],"which":[70],"significantly":[72],"higher":[73,102],"(p":[74,103],"<":[75],"0.01)":[76],"than":[77],"that":[78,109],"obtained":[82,112],"animal":[84,114],"rennet;":[85],"at":[86],"end":[88],"ripening":[90],"nonprotein":[92],"produced":[96,147],"slightly":[101],">":[104],"0.05)":[105],"cheeses":[111],"rennet.":[115],"Microbial":[116],"counts":[117],"used":[121],"for":[122],"making":[123],"high":[126],"groups":[131,141],"analyzed.":[132],"Despite":[133],"slight":[134],"counts,":[137],"main":[139],"microbial":[140],"analyzed":[142],"similar":[144],"both":[149],"throughout":[153]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}