{"id":"https://openalex.org/W2093935547","doi":"https://doi.org/10.1074/jbc.m512203200","title":"Persistent S-Nitrosation of Complex I and Other Mitochondrial Membrane Proteins by S-Nitrosothiols but Not Nitric Oxide or Peroxynitrite","display_name":"Persistent S-Nitrosation of Complex I and Other Mitochondrial Membrane Proteins by S-Nitrosothiols but Not Nitric Oxide or Peroxynitrite","publication_year":2006,"publication_date":"2006-02-15","ids":{"openalex":"https://openalex.org/W2093935547","doi":"https://doi.org/10.1074/jbc.m512203200","mag":"2093935547","pmid":"https://pubmed.ncbi.nlm.nih.gov/16481325"},"language":"en","primary_location":{"id":"doi:10.1074/jbc.m512203200","doi":"https://doi.org/10.1074/jbc.m512203200","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m512203200","pdf_url":"http://www.jbc.org/article/S0021925819563542/pdf","source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"http://www.jbc.org/article/S0021925819563542/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082652255","display_name":"Christina Catherine Dahm","orcid":"https://orcid.org/0000-0003-0481-2893","observed_orcids":["https://orcid.org/0000-0003-0481-2893"]},"institutions":[{"id":"https://openalex.org/I79266365","display_name":"MRC Mitochondrial Biology Unit","ror":"https://ror.org/01vdt8f48","country_code":"GB","type":"facility","lineage":["https://openalex.org/I241749","https://openalex.org/I4210087105","https://openalex.org/I79266365","https://openalex.org/I90344618"]},{"id":"https://openalex.org/I87048295","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I87048295"]},{"id":"https://openalex.org/I90344618","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517","country_code":"GB","type":"government","lineage":["https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Christina C. Dahm","raw_affiliation_strings":["Medical Research Council Dunn Human Nutrition Unit, Wellcome Trust/Medical Research Council Building, Hills Road, Cambridge CB2 2XY, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Research Council Dunn Human Nutrition Unit, Wellcome Trust/Medical Research Council Building, Hills Road, Cambridge CB2 2XY, United Kingdom","institution_ids":["https://openalex.org/I79266365","https://openalex.org/I87048295","https://openalex.org/I90344618"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104453861","display_name":"Kevin P. Moore","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Kevin Moore","raw_affiliation_strings":["Department of Medicine, University College London, Rowland Hill Street, London NW3 2PF, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University College London, Rowland Hill Street, London NW3 2PF, United Kingdom","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062511010","display_name":"Michael P. Murphy","orcid":"https://orcid.org/0000-0003-1115-9618","observed_orcids":["https://orcid.org/0000-0003-1115-9618"]},"institutions":[{"id":"https://openalex.org/I79266365","display_name":"MRC Mitochondrial Biology Unit","ror":"https://ror.org/01vdt8f48","country_code":"GB","type":"facility","lineage":["https://openalex.org/I241749","https://openalex.org/I4210087105","https://openalex.org/I79266365","https://openalex.org/I90344618"]},{"id":"https://openalex.org/I87048295","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I87048295"]},{"id":"https://openalex.org/I90344618","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517","country_code":"GB","type":"government","lineage":["https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Michael P. Murphy","raw_affiliation_strings":["Medical Research Council Dunn Human Nutrition Unit, Wellcome Trust/Medical Research Council Building, Hills Road, Cambridge CB2 2XY, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Research Council Dunn Human Nutrition Unit, Wellcome Trust/Medical Research Council Building, Hills Road, Cambridge CB2 2XY, United Kingdom","institution_ids":["https://openalex.org/I79266365","https://openalex.org/I87048295","https://openalex.org/I90344618"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5062511010"],"corresponding_institution_ids":["https://openalex.org/I79266365","https://openalex.org/I87048295","https://openalex.org/I90344618"],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":{"value":3430,"currency":"USD","value_usd":3430},"fwci":6.8492,"has_fulltext":true,"cited_by_count":196,"citation_normalized_percentile":{"value":0.98354861,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"281","issue":"15","first_page":"10056","last_page":"10065"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.7836999893188477,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.7836999893188477,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.1688999980688095,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.0284000001847744,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/s-nitrosylation","display_name":"S-nitrosylation","score":0.9810000061988831},{"id":"https://openalex.org/keywords/s-nitrosothiols","display_name":"S-nitrosothiols","score":0.9729999899864197},{"id":"https://openalex.org/keywords/respiratory-chain-complex-i","display_name":"respiratory chain complex I","score":0.7929999828338623},{"id":"https://openalex.org/keywords/mitochondrial-membrane-proteins","display_name":"mitochondrial membrane proteins","score":0.9509999752044678},{"id":"https://openalex.org/keywords/s-nitrosoglutathione","display_name":"S-nitrosoglutathione","score":0.8479999899864197},{"id":"https://openalex.org/keywords/s-nitroso-n-acetylpenicillamine","display_name":"S-nitroso-N-acetylpenicillamine","score":0.9929999709129333},{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":0.8500000238418579},{"id":"https://openalex.org/keywords/peroxynitrite","display_name":"peroxynitrite","score":0.9990000128746033},{"id":"https://openalex.org/keywords/protein-thiol-oxidation","display_name":"protein thiol oxidation","score":0.8600000143051147},{"id":"https://openalex.org/keywords/glutathione","display_name":"glutathione","score":0.7480000257492065},{"id":"https://openalex.org/keywords/nitrosative-stress","display_name":"nitrosative stress","score":0.875},{"id":"https://openalex.org/keywords/superoxide-production","display_name":"superoxide production","score":0.9850000143051147},{"id":"https://openalex.org/keywords/parkinson-s-disease","display_name":"Parkinson's disease","score":0.8050000071525574},{"id":"https://openalex.org/keywords/sepsis","display_name":"sepsis","score":0.9990000128746033}],"concepts":[{"id":"https://openalex.org/C2778784160","wikidata":"https://www.wikidata.org/wiki/Q419130","display_name":"Peroxynitrite","level":4,"score":0.9681441783905029},{"id":"https://openalex.org/C104882015","wikidata":"https://www.wikidata.org/wiki/Q3408495","display_name":"Nitrosation","level":2,"score":0.8863793015480042},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8396519422531128},{"id":"https://openalex.org/C2781324293","wikidata":"https://www.wikidata.org/wiki/Q220410","display_name":"Thiol","level":2,"score":0.7097137570381165},{"id":"https://openalex.org/C519581460","wikidata":"https://www.wikidata.org/wiki/Q207843","display_name":"Nitric oxide","level":2,"score":0.6913353800773621},{"id":"https://openalex.org/C2777553025","wikidata":"https://www.wikidata.org/wiki/Q25323683","display_name":"S-Nitrosylation","level":4,"score":0.6719144582748413},{"id":"https://openalex.org/C538909803","wikidata":"https://www.wikidata.org/wiki/Q116907","display_name":"Glutathione","level":3,"score":0.6313344240188599},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.55223149061203},{"id":"https://openalex.org/C2776015013","wikidata":"https://www.wikidata.org/wiki/Q7387071","display_name":"S-Nitrosoglutathione","level":4,"score":0.5504494905471802},{"id":"https://openalex.org/C45068187","wikidata":"https://www.wikidata.org/wiki/Q9050270","display_name":"Nitrosylation","level":3,"score":0.5153824687004089},{"id":"https://openalex.org/C2779525624","wikidata":"https://www.wikidata.org/wiki/Q225595","display_name":"Reactive nitrogen species","level":3,"score":0.4683099687099457},{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.44792601466178894},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.4028075039386749},{"id":"https://openalex.org/C2780795997","wikidata":"https://www.wikidata.org/wiki/Q413283","display_name":"Superoxide","level":3,"score":0.36901482939720154},{"id":"https://openalex.org/C2779201268","wikidata":"https://www.wikidata.org/wiki/Q186474","display_name":"Cysteine","level":3,"score":0.26486074924468994},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.13921627402305603},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.08233612775802612}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004220","descriptor_name":"Disulfides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004591","descriptor_name":"Electrophoresis, Polyacrylamide Gel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005978","descriptor_name":"Glutathione","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007425","descriptor_name":"Intracellular Membranes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008930","descriptor_name":"Mitochondria, Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008956","descriptor_name":"Models, Chemical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009569","descriptor_name":"Nitric Oxide","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009569","descriptor_name":"Nitric Oxide","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D009603","descriptor_name":"Nitroso Compounds","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010101","descriptor_name":"Oxygen Consumption","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013438","descriptor_name":"Sulfhydryl Compounds","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013481","descriptor_name":"Superoxides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015151","descriptor_name":"Immunoblotting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015538","descriptor_name":"Nitrosation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018805","descriptor_name":"Sepsis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D026403","descriptor_name":"S-Nitrosothiols","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D026423","descriptor_name":"S-Nitroso-N-Acetylpenicillamine","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D030421","descriptor_name":"Peroxynitrous Acid","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1074/jbc.m512203200","doi":"https://doi.org/10.1074/jbc.m512203200","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m512203200","pdf_url":"http://www.jbc.org/article/S0021925819563542/pdf","source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},{"id":"pmid:16481325","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16481325","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of biological chemistry","raw_type":"Journal Article"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:40516","doi":null,"is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/40516/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"JOURNAL OF BIOLOGICAL CHEMISTRY , 281 (15) pp. 10056-10065. (2006)","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1074/jbc.m512203200","doi":"https://doi.org/10.1074/jbc.m512203200","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m512203200","pdf_url":"http://www.jbc.org/article/S0021925819563542/pdf","source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.4000000059604645,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2093935547.pdf","grobid_xml":"https://content.openalex.org/works/W2093935547.grobid-xml"},"referenced_works_count":78,"referenced_works":["https://openalex.org/W36502835","https://openalex.org/W158267464","https://openalex.org/W937204623","https://openalex.org/W1044794178","https://openalex.org/W1482813056","https://openalex.org/W1492951734","https://openalex.org/W1500094754","https://openalex.org/W1505439087","https://openalex.org/W1506043065","https://openalex.org/W1528220495","https://openalex.org/W1547809857","https://openalex.org/W1566232888","https://openalex.org/W1570253404","https://openalex.org/W1602425415","https://openalex.org/W1761291408","https://openalex.org/W1965586048","https://openalex.org/W1981845473","https://openalex.org/W1982778052","https://openalex.org/W1990798856","https://openalex.org/W1991308916","https://openalex.org/W2001251332","https://openalex.org/W2001923189","https://openalex.org/W2008574021","https://openalex.org/W2009819178","https://openalex.org/W2011582460","https://openalex.org/W2012634726","https://openalex.org/W2013628401","https://openalex.org/W2016753829","https://openalex.org/W2018752752","https://openalex.org/W2022295123","https://openalex.org/W2025338400","https://openalex.org/W2026117623","https://openalex.org/W2026728447","https://openalex.org/W2030956146","https://openalex.org/W2031065747","https://openalex.org/W2034188480","https://openalex.org/W2036825042","https://openalex.org/W2037159578","https://openalex.org/W2046472521","https://openalex.org/W2046835047","https://openalex.org/W2047545717","https://openalex.org/W2051252921","https://openalex.org/W2054027791","https://openalex.org/W2054930602","https://openalex.org/W2055308573","https://openalex.org/W2055961900","https://openalex.org/W2058137293","https://openalex.org/W2060263803","https://openalex.org/W2061144992","https://openalex.org/W2063078080","https://openalex.org/W2063968553","https://openalex.org/W2070235240","https://openalex.org/W2072234605","https://openalex.org/W2077103811","https://openalex.org/W2080128777","https://openalex.org/W2081595932","https://openalex.org/W2083636496","https://openalex.org/W2087926587","https://openalex.org/W2090046344","https://openalex.org/W2090096368","https://openalex.org/W2091380103","https://openalex.org/W2092721077","https://openalex.org/W2094120111","https://openalex.org/W2096335830","https://openalex.org/W2101032933","https://openalex.org/W2107366065","https://openalex.org/W2115167405","https://openalex.org/W2123550664","https://openalex.org/W2125935300","https://openalex.org/W2133966054","https://openalex.org/W2134760535","https://openalex.org/W2139871065","https://openalex.org/W2141522397","https://openalex.org/W2143445854","https://openalex.org/W2146497928","https://openalex.org/W2165518882","https://openalex.org/W2342792498","https://openalex.org/W4232534952"],"related_works":["https://openalex.org/W7073962581","https://openalex.org/W2020937749","https://openalex.org/W2096335830","https://openalex.org/W2089884218","https://openalex.org/W2086448760","https://openalex.org/W2036982001","https://openalex.org/W6889288313","https://openalex.org/W2326236209","https://openalex.org/W2735370877","https://openalex.org/W4210579167"],"abstract_inverted_index":{"S-nitrosation":[0,115,159,186,191,229],"of":[1,13,35,40,78,99,130,192,200],"mitochondrial":[2,49,133,165],"proteins":[3],"has":[4,23],"been":[5,25],"proposed":[6],"to":[7,9,58,91,118,222],"contribute":[8],"the":[10,33,38,73,100,164],"pathophysiological":[11],"interactions":[12],"nitric":[14],"oxide":[15],"(NO)":[16],"and":[17,71,88,230,242],"its":[18],"derivatives":[19],"with":[20,66,96,179,196,212],"mitochondria":[21],"but":[22,126,142],"not":[24,143],"shown":[26],"directly.":[27],"Furthermore,":[28],"little":[29],"is":[30,168],"known":[31],"about":[32,97],"mechanism":[34],"formation":[36],"or":[37,68,114,146],"fate":[39],"these":[41],"putative":[42],"S-nitrosothiols.":[43,131],"Here":[44],"we":[45],"have":[46],"determined":[47],"whether":[48],"membrane":[50,134],"protein":[51,79,93,102,111,124,135,151],"thiols":[52,80,103,125,136,152],"can":[53],"be":[54],"S-nitrosated":[55,138,150,175],"on":[56,116],"exposure":[57,117],"free":[59],"NO":[60,74,145],"from":[61,216],"3,3-bis(aminoethyl)-1-hydroxy-2-oxo-1-triazene":[62],"(DETA-NONOate)":[63],"by":[64,72,84,139,144,147,156,176,205],"interaction":[65],"S-nitrosoglutathione":[67],"S-nitroso-N-acetylpenicillamine":[69,89],"(SNAP)":[70],"derivative":[75],"peroxynitrite.":[76,148],"S-Nitrosation":[77,208],"was":[81,109,174,203,209],"measured":[82],"directly":[83],"chemiluminescence":[85],"detection.":[86],"S-Nitrosoglutathione":[87],"led":[90],"extensive":[92],"thiol":[94,112,206],"oxidation,":[95],"30%":[98],"modified":[101],"persistently":[104],"S-nitrosated.":[105],"In":[106],"contrast,":[107],"there":[108],"no":[110],"oxidation":[113],"3,3-bis":[119],"(aminoethyl)-1-hydroxy-2-oxo-1-triazene.":[120],"Peroxynitrite":[121],"extensively":[122],"oxidized":[123],"produced":[127],"negligible":[128],"amounts":[129],"Therefore,":[132],"are":[137],"preformed":[140],"S-nitrosothiols":[141],"These":[149,219],"were":[153],"readily":[154],"reduced":[155],"glutathione,":[157],"so":[158],"will":[160],"only":[161],"persist":[162],"when":[163],"glutathione":[166],"pool":[167],"oxidized.":[169],"Respiratory":[170],"chain":[171],"complex":[172,193,217,227],"I":[173,194,228],"S-nitrosothiols,":[177],"consistent":[178],"it":[180],"being":[181],"an":[182],"important":[183],"target":[184],"for":[185,226],"during":[187,233],"nitrosative":[188,234],"stress.":[189],"The":[190],"correlated":[195],"a":[197,223],"significant":[198,224],"loss":[199],"activity":[201],"that":[202],"reversed":[204],"reductants.":[207],"also":[210],"associated":[211],"increased":[213],"superoxide":[214],"production":[215],"I.":[218],"findings":[220],"point":[221],"role":[225],"consequent":[231],"dysfunction":[232],"stress":[235],"in":[236],"disorders":[237],"such":[238],"as":[239],"Parkinson":[240],"disease":[241],"sepsis.":[243]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":16},{"year":2012,"cited_by_count":13}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}