{"id":"https://openalex.org/W2093767262","doi":"https://doi.org/10.1121/1.3588660","title":"Three-dimensional detection of metastases in freshly excised human lymph nodes using quantitative ultrasound backscatter and envelope parameters.","display_name":"Three-dimensional detection of metastases in freshly excised human lymph nodes using quantitative ultrasound backscatter and envelope parameters.","publication_year":2011,"publication_date":"2011-04-01","ids":{"openalex":"https://openalex.org/W2093767262","doi":"https://doi.org/10.1121/1.3588660","mag":"2093767262"},"language":"en","primary_location":{"id":"doi:10.1121/1.3588660","doi":"https://doi.org/10.1121/1.3588660","is_oa":false,"landing_page_url":"https://doi.org/10.1121/1.3588660","pdf_url":null,"source":{"id":"https://openalex.org/S11296630","display_name":"The Journal of the Acoustical Society of America","issn_l":"0001-4966","issn":["0001-4966","1520-8524","1520-9024"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","ccf-b","cwts-core","dongbi-b","erih-plus","jufo-3","ki-jl-1","medline","norway-2","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320226","host_organization_name":"Acoustical Society of America","host_organization_lineage":["https://openalex.org/P4310320226"],"host_organization_lineage_names":["Acoustical Society of America"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of the Acoustical Society of America","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076167293","display_name":"Jonathan Mamou","orcid":"https://orcid.org/0000-0002-9412-165X","observed_orcids":["https://orcid.org/0000-0002-9412-165X"]},"institutions":[{"id":"https://openalex.org/I4210132419","display_name":"Riverside Research Institute","ror":"https://ror.org/02tvg0w73","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210132419"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jonathan Mamou","raw_affiliation_strings":["Lizzi Ctr., Riverside Res. Inst., New York, NY, jmamou@rri-usa.org"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lizzi Ctr., Riverside Res. Inst., New York, NY, jmamou@rri-usa.org","institution_ids":["https://openalex.org/I4210132419"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044158122","display_name":"Alain Coron","orcid":"https://orcid.org/0000-0003-0599-1133","observed_orcids":["https://orcid.org/0000-0003-0599-1133"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Alain Coron","raw_affiliation_strings":["CNRS and Univ. of Paris, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CNRS and Univ. of Paris, Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I204730241"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029223419","display_name":"Emi Saegusa-Beecroft","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1331384533","display_name":"University of Hawaii System","ror":"https://ror.org/03tzaeb71","country_code":"US","type":"education","lineage":["https://openalex.org/I1331384533"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Emi Saegusa-Beecroft","raw_affiliation_strings":["Univ. of Hawaii, Honolulu, HI"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of Hawaii, Honolulu, HI","institution_ids":["https://openalex.org/I1331384533"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102023246","display_name":"Masaki Hata","orcid":"https://orcid.org/0000-0002-9003-6562","observed_orcids":["https://orcid.org/0000-0002-9003-6562"]},"institutions":[{"id":"https://openalex.org/I1331384533","display_name":"University of Hawaii System","ror":"https://ror.org/03tzaeb71","country_code":"US","type":"education","lineage":["https://openalex.org/I1331384533"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Masaki Hata","raw_affiliation_strings":["Univ. of Hawaii, Honolulu, HI"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of Hawaii, Honolulu, HI","institution_ids":["https://openalex.org/I1331384533"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004000426","display_name":"Michael L. Oelze","orcid":"https://orcid.org/0000-0002-3099-7425","observed_orcids":["https://orcid.org/0000-0002-3099-7425"]},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael L. Oelze","raw_affiliation_strings":["Univ. of Illinois, Urbana-Champaign, IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of Illinois, Urbana-Champaign, IL","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052283859","display_name":"Eugene T. Yanagihara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1331384533","display_name":"University of Hawaii System","ror":"https://ror.org/03tzaeb71","country_code":"US","type":"education","lineage":["https://openalex.org/I1331384533"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eugene Yanagihara","raw_affiliation_strings":["Univ. of Hawaii, Honolulu, HI"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of Hawaii, Honolulu, HI","institution_ids":["https://openalex.org/I1331384533"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044970442","display_name":"Tadashi Yamaguchi","orcid":"https://orcid.org/0000-0001-5761-4888","observed_orcids":["https://orcid.org/0000-0001-5761-4888"]},"institutions":[{"id":"https://openalex.org/I159385669","display_name":"Chiba University","ror":"https://ror.org/01hjzeq58","country_code":"JP","type":"education","lineage":["https://openalex.org/I159385669"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tadashi Yamaguchi","raw_affiliation_strings":["Chiba Univ., Chiba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chiba Univ., Chiba, Japan","institution_ids":["https://openalex.org/I159385669"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077810746","display_name":"Pascal Laugier","orcid":"https://orcid.org/0000-0002-7498-0262","observed_orcids":["https://orcid.org/0000-0002-7498-0262"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Pascal Laugier","raw_affiliation_strings":["CNRS and Univ. of Paris, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CNRS and Univ. of Paris, Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I204730241"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112213212","display_name":"Junji Machi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1331384533","display_name":"University of Hawaii System","ror":"https://ror.org/03tzaeb71","country_code":"US","type":"education","lineage":["https://openalex.org/I1331384533"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Junji Machi","raw_affiliation_strings":["Univ. of Hawaii, Honolulu, HI"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of Hawaii, Honolulu, HI","institution_ids":["https://openalex.org/I1331384533"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030215699","display_name":"Ernest Joseph Feleppa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210132419","display_name":"Riverside Research Institute","ror":"https://ror.org/02tvg0w73","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210132419"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ernest J. Feleppa","raw_affiliation_strings":["Riverside Res. Inst., New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Riverside Res. Inst., New York, NY","institution_ids":["https://openalex.org/I4210132419"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"129","issue":"4_Supplement","first_page":"2610","last_page":"2610"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10727","display_name":"Ultrasound Imaging and Elastography","score":0.975600004196167,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10727","display_name":"Ultrasound Imaging and Elastography","score":0.975600004196167,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10958","display_name":"Ultrasound and Hyperthermia Applications","score":0.006899999920278788,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":0.0066999997943639755,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lymph-node-metastasis-detection","display_name":"lymph node metastasis detection","score":0.8659999966621399},{"id":"https://openalex.org/keywords/quantitative-ultrasound","display_name":"quantitative ultrasound","score":0.9459999799728394},{"id":"https://openalex.org/keywords/envelope-statistics","display_name":"envelope statistics","score":0.8309999704360962},{"id":"https://openalex.org/keywords/3d-ultrasound","display_name":"3D ultrasound","score":0.7860000133514404},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.6230000257492065},{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"colorectal cancer","score":1.0},{"id":"https://openalex.org/keywords/linear-discriminant-analysis","display_name":"linear discriminant analysis","score":0.6389999985694885},{"id":"https://openalex.org/keywords/tumor-staging","display_name":"tumor staging","score":0.3319999873638153}],"concepts":[{"id":"https://openalex.org/C69738355","wikidata":"https://www.wikidata.org/wiki/Q1228929","display_name":"Linear discriminant analysis","level":2,"score":0.5470011830329895},{"id":"https://openalex.org/C143753070","wikidata":"https://www.wikidata.org/wiki/Q162564","display_name":"Ultrasound","level":2,"score":0.5401368141174316},{"id":"https://openalex.org/C2779720271","wikidata":"https://www.wikidata.org/wiki/Q179422","display_name":"Lymph","level":2,"score":0.5358544588088989},{"id":"https://openalex.org/C2780849966","wikidata":"https://www.wikidata.org/wiki/Q170758","display_name":"Lymph node","level":2,"score":0.482754647731781},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4705291986465454},{"id":"https://openalex.org/C65155139","wikidata":"https://www.wikidata.org/wiki/Q5380912","display_name":"Envelope (radar)","level":3,"score":0.46628403663635254},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.4557374119758606},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.4505395293235779},{"id":"https://openalex.org/C30354325","wikidata":"https://www.wikidata.org/wiki/Q204667","display_name":"Backscatter (email)","level":3,"score":0.412075400352478},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.358842670917511},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2888956069946289},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.2549918591976166},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.24667015671730042},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.19873881340026855},{"id":"https://openalex.org/C554190296","wikidata":"https://www.wikidata.org/wiki/Q47528","display_name":"Radar","level":2,"score":0.0},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0},{"id":"https://openalex.org/C555944384","wikidata":"https://www.wikidata.org/wiki/Q249","display_name":"Wireless","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1121/1.3588660","doi":"https://doi.org/10.1121/1.3588660","is_oa":false,"landing_page_url":"https://doi.org/10.1121/1.3588660","pdf_url":null,"source":{"id":"https://openalex.org/S11296630","display_name":"The Journal of the Acoustical Society of America","issn_l":"0001-4966","issn":["0001-4966","1520-8524","1520-9024"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","ccf-b","cwts-core","dongbi-b","erih-plus","jufo-3","ki-jl-1","medline","norway-2","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320226","host_organization_name":"Acoustical Society of America","host_organization_lineage":["https://openalex.org/P4310320226"],"host_organization_lineage_names":["Acoustical Society of America"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of the Acoustical Society of America","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2037264419","https://openalex.org/W1982626474","https://openalex.org/W2080268200","https://openalex.org/W135281619","https://openalex.org/W2097974676","https://openalex.org/W2758224290","https://openalex.org/W4296564038","https://openalex.org/W2537893439","https://openalex.org/W1999085471","https://openalex.org/W4310783778"],"abstract_inverted_index":{"High-frequency":[0],"quantitative":[1],"ultrasound":[2,60],"(QUS)":[3],"may":[4,190],"offer":[5],"a":[6,160,179],"reliable":[7],"means":[8],"of":[9,18,52,135,153,162,174,181],"identifying":[10],"tumor":[11],"foci":[12,105],"in":[13,72,93,106,193],"dissected":[14],"lymph":[15,79],"nodes.":[16,80,165,184,199],"Detection":[17],"metastases":[19,130],"is":[20,44],"essential":[21],"for":[22,129,149,159,178],"staging":[23],"and":[24,66,88,140],"treatment":[25],"planning.":[26],"Conventional":[27],"histopathology":[28],"methods":[29,48],"do":[30],"not":[31],"allow":[32],"nodes":[33,196],"to":[34,45,49,64,102],"be":[35,191],"examined":[36],"over":[37],"their":[38],"entire":[39],"volume.":[40],"Therefore,":[41],"our":[42],"objective":[43],"develop":[46],"QUS":[47,82,111,127,138,155,170,189],"improve":[50],"detection":[51,131],"clinically":[53],"significant":[54],"lymph-node":[55],"metastases.":[56],"A":[57],"single-element":[58],"26-MHz":[59],"transducer":[61],"was":[62,97,113,157,176],"used":[63],"scan":[65],"digitally":[67],"acquire":[68],"rf":[69],"echo-signal":[70],"data":[71],"three-dimensional":[73],"(3D)":[74],"from":[75,197],"more":[76],"than":[77],"200":[78],"Thirteen":[81],"estimates":[83,112,128,156],"based":[84,109],"on":[85,110],"backscatter":[86],"spectra":[87],"envelope":[89],"statistics":[90],"were":[91,123,132],"computed":[92],"3D.":[94,107],"Serial-sectioning":[95],"histology":[96,142],"performed":[98,114],"at":[99],"50-\u03bcm":[100],"intervals":[101],"depict":[103],"cancer":[104],"Classification":[108],"using":[115,167],"linear-discriminant":[116],"analyzes;":[117],"areas":[118],"under":[119],"ROC":[120],"curves":[121],"(AUCs)":[122],"computed.":[124],"The":[125,147],"most-significant":[126],"identified.":[133],"Comparison":[134],"the":[136,150],"3D":[137,141],"results":[139,186],"showed":[143],"promising":[144],"classification":[145],"results.":[146],"AUC":[148,173],"linear":[151],"combination":[152],"four":[154],"0.91":[158],"dataset":[161,180],"73":[163],"breast-cancer":[164],"Similarly,":[166],"only":[168],"two":[169],"estimates,":[171],"an":[172],"0.97":[175],"obtained":[177],"143":[182],"colorectal-cancer":[183],"These":[185],"suggest":[187],"that":[188],"effective":[192],"distinguishing":[194],"metastatic":[195],"normal":[198]},"counts_by_year":[{"year":2018,"cited_by_count":1}],"updated_date":"2026-10-22T18:32:59.640997","created_date":"2016-06-24T00:00:00"}