{"id":"https://openalex.org/W2093723325","doi":"https://doi.org/10.1177/1933719110381923","title":"Bioengineering Anembryonic Human Trophoblast Vesicles","display_name":"Bioengineering Anembryonic Human Trophoblast Vesicles","publication_year":2010,"publication_date":"2010-10-27","ids":{"openalex":"https://openalex.org/W2093723325","doi":"https://doi.org/10.1177/1933719110381923","mag":"2093723325","pmid":"https://pubmed.ncbi.nlm.nih.gov/20978180","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3343138"},"language":"en","primary_location":{"id":"doi:10.1177/1933719110381923","doi":"https://doi.org/10.1177/1933719110381923","is_oa":true,"landing_page_url":"https://doi.org/10.1177/1933719110381923","pdf_url":"https://link.springer.com/content/pdf/10.1177/1933719110381923.pdf","source":{"id":"https://openalex.org/S68157034","display_name":"Reproductive Sciences","issn_l":"1933-7191","issn":["1933-7191","1933-7205"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproductive Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://link.springer.com/content/pdf/10.1177/1933719110381923.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113574361","display_name":"Jared C. Robins","orcid":"https://orcid.org/0000-0002-9796-875X","observed_orcids":["https://orcid.org/0000-0002-9796-875X"]},"institutions":[{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]},{"id":"https://openalex.org/I4210133025","display_name":"Women & Infants Hospital of Rhode Island","ror":"https://ror.org/03z8sn326","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210133025"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jared C. Robins","raw_affiliation_strings":["Departments of Obstetrics and Gynecology, Warren Alpert Medical School at Brown University, Providence, RI 02067, USA. JRobins@wihri.org","Departments of Obstetrics and Gynecology, Warren Alpert School of Medicine at Brown University, Women and Infants Hospital of Rhode Island, Providence, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Obstetrics and Gynecology, Warren Alpert Medical School at Brown University, Providence, RI 02067, USA. JRobins@wihri.org","institution_ids":["https://openalex.org/I27804330"]},{"raw_affiliation_string":"Departments of Obstetrics and Gynecology, Warren Alpert School of Medicine at Brown University, Women and Infants Hospital of Rhode Island, Providence, USA","institution_ids":["https://openalex.org/I27804330","https://openalex.org/I4210133025"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054959711","display_name":"Jeffrey R. Morgan","orcid":"https://orcid.org/0000-0002-7546-3443","observed_orcids":["https://orcid.org/0000-0002-7546-3443"]},"institutions":[{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey R. Morgan","raw_affiliation_strings":["Department of Molecular Pharmacology, Physiology and Biotechnology and Center for Biomedical Engineering, Warren Alpert Medical School at Brown University, Providence, RI, USA","Department of Molecular Pharmacology, Physiology and Biotechnology and Center for Biomedical Engineering, Warren Alpert Medical School at Brown University, Providence, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Pharmacology, Physiology and Biotechnology and Center for Biomedical Engineering, Warren Alpert Medical School at Brown University, Providence, RI, USA","institution_ids":["https://openalex.org/I27804330"]},{"raw_affiliation_string":"Department of Molecular Pharmacology, Physiology and Biotechnology and Center for Biomedical Engineering, Warren Alpert Medical School at Brown University, Providence, USA","institution_ids":["https://openalex.org/I27804330"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103567865","display_name":"Paula M. Krueger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]},{"id":"https://openalex.org/I4210133025","display_name":"Women & Infants Hospital of Rhode Island","ror":"https://ror.org/03z8sn326","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210133025"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paula Krueger","raw_affiliation_strings":["Women and Infants Hospital of Rhode Island , 101 Dudley Street , Providence , RI 02067 , USA","Departments of Obstetrics and Gynecology, Warren Alpert School of Medicine at Brown University, Women and Infants Hospital of Rhode Island, Providence, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Women and Infants Hospital of Rhode Island , 101 Dudley Street , Providence , RI 02067 , USA","institution_ids":["https://openalex.org/I4210133025"]},{"raw_affiliation_string":"Departments of Obstetrics and Gynecology, Warren Alpert School of Medicine at Brown University, Women and Infants Hospital of Rhode Island, Providence, USA","institution_ids":["https://openalex.org/I27804330","https://openalex.org/I4210133025"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108637154","display_name":"Sandra Ann Carson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]},{"id":"https://openalex.org/I4210133025","display_name":"Women & Infants Hospital of Rhode Island","ror":"https://ror.org/03z8sn326","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210133025"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sandra A. Carson","raw_affiliation_strings":["Departments of Obstetrics and Gynecology, Warren Alpert School of Medicine at Brown University, Women and Infants Hospital of Rhode Island, 101 Dudley Street, Providence, RI, 02067, USA","Departments of Obstetrics and Gynecology, Warren Alpert School of Medicine at Brown University, Women and Infants Hospital of Rhode Island, Providence, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Obstetrics and Gynecology, Warren Alpert School of Medicine at Brown University, Women and Infants Hospital of Rhode Island, 101 Dudley Street, Providence, RI, 02067, USA","institution_ids":["https://openalex.org/I27804330","https://openalex.org/I4210133025"]},{"raw_affiliation_string":"Departments of Obstetrics and Gynecology, Warren Alpert School of Medicine at Brown University, Women and Infants Hospital of Rhode Island, Providence, USA","institution_ids":["https://openalex.org/I27804330","https://openalex.org/I4210133025"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5113574361"],"corresponding_institution_ids":["https://openalex.org/I27804330","https://openalex.org/I4210133025"],"apc_list":{"value":3090,"currency":"USD","value_usd":3090},"apc_paid":null,"fwci":0.3776,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.64870507,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"18","issue":"2","first_page":"128","last_page":"135"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.698199987411499,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.698199987411499,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.0794999971985817,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11510","display_name":"Reproductive System and Pregnancy","score":0.05550000071525574,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/trophoblast","display_name":"trophoblast","score":0.8109999895095825},{"id":"https://openalex.org/keywords/3d-cell-culture","display_name":"3D cell culture","score":0.796999990940094},{"id":"https://openalex.org/keywords/agarose-gel","display_name":"agarose gel","score":0.7350000143051147},{"id":"https://openalex.org/keywords/spheroids","display_name":"spheroids","score":0.6520000100135803},{"id":"https://openalex.org/keywords/bioreactors","display_name":"bioreactors","score":0.734000027179718},{"id":"https://openalex.org/keywords/cell-cell-interactions","display_name":"cell-cell interactions","score":0.6819999814033508},{"id":"https://openalex.org/keywords/placenta","display_name":"placenta","score":0.6909999847412109},{"id":"https://openalex.org/keywords/microtissues","display_name":"microtissues","score":0.7260000109672546},{"id":"https://openalex.org/keywords/basement-membrane-invasion","display_name":"basement membrane invasion","score":0.8270000219345093},{"id":"https://openalex.org/keywords/fibronectin","display_name":"fibronectin","score":0.7929999828338623},{"id":"https://openalex.org/keywords/vesicle-ultrastructure","display_name":"vesicle ultrastructure","score":0.671999990940094}],"concepts":[{"id":"https://openalex.org/C2777495146","wikidata":"https://www.wikidata.org/wiki/Q1889778","display_name":"Trophoblast","level":5,"score":0.5547022819519043},{"id":"https://openalex.org/C2776210078","wikidata":"https://www.wikidata.org/wiki/Q351870","display_name":"Reproductive medicine","level":3,"score":0.4436270296573639},{"id":"https://openalex.org/C130316041","wikidata":"https://www.wikidata.org/wiki/Q189206","display_name":"Vesicle","level":3,"score":0.43556177616119385},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.36262595653533936},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3618369698524475},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3262184262275696},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.12688389420509338},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.11336159706115723},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.065245121717453},{"id":"https://openalex.org/C2776953305","wikidata":"https://www.wikidata.org/wiki/Q1212935","display_name":"Placenta","level":4,"score":0.0},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.0},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D001485","descriptor_name":"Basement Membrane","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002450","descriptor_name":"Cell Communication","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005353","descriptor_name":"Fibronectins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008854","descriptor_name":"Microscopy, Electron","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012685","descriptor_name":"Sepharose","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014327","descriptor_name":"Trophoblasts","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D014327","descriptor_name":"Trophoblasts","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D018613","descriptor_name":"Microscopy, Confocal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018874","descriptor_name":"Spheroids, Cellular","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D018874","descriptor_name":"Spheroids, Cellular","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D019149","descriptor_name":"Bioreactors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020136","descriptor_name":"Hydrogel, Polyethylene Glycol Dimethacrylate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057005","descriptor_name":"Bioengineering","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1177/1933719110381923","doi":"https://doi.org/10.1177/1933719110381923","is_oa":true,"landing_page_url":"https://doi.org/10.1177/1933719110381923","pdf_url":"https://link.springer.com/content/pdf/10.1177/1933719110381923.pdf","source":{"id":"https://openalex.org/S68157034","display_name":"Reproductive Sciences","issn_l":"1933-7191","issn":["1933-7191","1933-7205"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproductive Sciences","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2387053","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3343138","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3343138","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3343138","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reprod Sci","raw_type":"Text"},{"id":"pmid:20978180","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20978180","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproductive sciences (Thousand Oaks, Calif.)","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1177/1933719110381923","doi":"https://doi.org/10.1177/1933719110381923","is_oa":true,"landing_page_url":"https://doi.org/10.1177/1933719110381923","pdf_url":"https://link.springer.com/content/pdf/10.1177/1933719110381923.pdf","source":{"id":"https://openalex.org/S68157034","display_name":"Reproductive Sciences","issn_l":"1933-7191","issn":["1933-7191","1933-7205"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproductive Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.4000000059604645}],"study_designs":[],"awards":[{"id":"https://openalex.org/G8033254419","display_name":null,"funder_award_id":"P20 RR108728","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2093723325.pdf","grobid_xml":"https://content.openalex.org/works/W2093723325.grobid-xml"},"referenced_works_count":26,"referenced_works":["https://openalex.org/W646088555","https://openalex.org/W1974159415","https://openalex.org/W1975833234","https://openalex.org/W1976839673","https://openalex.org/W1977143051","https://openalex.org/W1983334409","https://openalex.org/W1984953670","https://openalex.org/W1986244792","https://openalex.org/W1989932193","https://openalex.org/W1993313340","https://openalex.org/W2004645548","https://openalex.org/W2014762318","https://openalex.org/W2024510213","https://openalex.org/W2028889986","https://openalex.org/W2040527378","https://openalex.org/W2057300185","https://openalex.org/W2078415101","https://openalex.org/W2086063762","https://openalex.org/W2090437792","https://openalex.org/W2091672036","https://openalex.org/W2123829995","https://openalex.org/W2123868192","https://openalex.org/W2131545249","https://openalex.org/W2131960777","https://openalex.org/W2415917762","https://openalex.org/W2890318234"],"related_works":["https://openalex.org/W2325180215","https://openalex.org/W1966118320","https://openalex.org/W2023238467","https://openalex.org/W2029440389","https://openalex.org/W7134534133","https://openalex.org/W1983334409","https://openalex.org/W2154743178","https://openalex.org/W4296106852","https://openalex.org/W1965893503","https://openalex.org/W2022499827"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}