{"id":"https://openalex.org/W2093547786","doi":"https://doi.org/10.1021/ja9701671","title":"Synthesis, Structure, and Biological Activity of a New Insulinomimetic Peroxovanadium Compound: Bisperoxovanadium Imidazole Monoanion","display_name":"Synthesis, Structure, and Biological Activity of a New Insulinomimetic Peroxovanadium Compound: Bisperoxovanadium Imidazole Monoanion","publication_year":1997,"publication_date":"1997-06-01","ids":{"openalex":"https://openalex.org/W2093547786","doi":"https://doi.org/10.1021/ja9701671","mag":"2093547786"},"language":"en","primary_location":{"id":"doi:10.1021/ja9701671","doi":"https://doi.org/10.1021/ja9701671","is_oa":false,"landing_page_url":"https://doi.org/10.1021/ja9701671","pdf_url":null,"source":{"id":"https://openalex.org/S111155417","display_name":"Journal of the American Chemical Society","issn_l":"0002-7863","issn":["0002-7863","1520-5126","1943-2984"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Chemical Society","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052889522","display_name":"Debbie C. Crans","orcid":"https://orcid.org/0000-0001-7792-3450","observed_orcids":["https://orcid.org/0000-0001-7792-3450"]},"institutions":[{"id":"https://openalex.org/I92446798","display_name":"Colorado State University","ror":"https://ror.org/03k1gpj17","country_code":"US","type":"education","lineage":["https://openalex.org/I92446798"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Debbie C. Crans","raw_affiliation_strings":["Department of Chemistry, Colorado State University Fort Collins, Colorado 80523-1872 Bayer Corporation, 400 Morgan Lane West Haven, Connecticut 06516-4175"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Colorado State University Fort Collins, Colorado 80523-1872 Bayer Corporation, 400 Morgan Lane West Haven, Connecticut 06516-4175","institution_ids":["https://openalex.org/I92446798"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045324658","display_name":"Anastasios D. Keramidas","orcid":"https://orcid.org/0000-0002-0446-8220","observed_orcids":["https://orcid.org/0000-0002-0446-8220"]},"institutions":[{"id":"https://openalex.org/I92446798","display_name":"Colorado State University","ror":"https://ror.org/03k1gpj17","country_code":"US","type":"education","lineage":["https://openalex.org/I92446798"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anastasios D. Keramidas","raw_affiliation_strings":["Department of Chemistry, Colorado State University Fort Collins, Colorado 80523-1872 Bayer Corporation, 400 Morgan Lane West Haven, Connecticut 06516-4175"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Colorado State University Fort Collins, Colorado 80523-1872 Bayer Corporation, 400 Morgan Lane West Haven, Connecticut 06516-4175","institution_ids":["https://openalex.org/I92446798"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070548732","display_name":"Helana Hoover-Litty","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I92446798","display_name":"Colorado State University","ror":"https://ror.org/03k1gpj17","country_code":"US","type":"education","lineage":["https://openalex.org/I92446798"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Helana Hoover-Litty","raw_affiliation_strings":["Department of Chemistry, Colorado State University Fort Collins, Colorado 80523-1872 Bayer Corporation, 400 Morgan Lane West Haven, Connecticut 06516-4175"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Colorado State University Fort Collins, Colorado 80523-1872 Bayer Corporation, 400 Morgan Lane West Haven, Connecticut 06516-4175","institution_ids":["https://openalex.org/I92446798"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110068728","display_name":"Oren P. Anderson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I92446798","display_name":"Colorado State University","ror":"https://ror.org/03k1gpj17","country_code":"US","type":"education","lineage":["https://openalex.org/I92446798"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Oren P. Anderson","raw_affiliation_strings":["Department of Chemistry, Colorado State University Fort Collins, Colorado 80523-1872 Bayer Corporation, 400 Morgan Lane West Haven, Connecticut 06516-4175"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Colorado State University Fort Collins, Colorado 80523-1872 Bayer Corporation, 400 Morgan Lane West Haven, Connecticut 06516-4175","institution_ids":["https://openalex.org/I92446798"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109873725","display_name":"Mary M. Miller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I92446798","display_name":"Colorado State University","ror":"https://ror.org/03k1gpj17","country_code":"US","type":"education","lineage":["https://openalex.org/I92446798"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mary M. Miller","raw_affiliation_strings":["Department of Chemistry, Colorado State University Fort Collins, Colorado 80523-1872 Bayer Corporation, 400 Morgan Lane West Haven, Connecticut 06516-4175"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Colorado State University Fort Collins, Colorado 80523-1872 Bayer Corporation, 400 Morgan Lane West Haven, Connecticut 06516-4175","institution_ids":["https://openalex.org/I92446798"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012342742","display_name":"Lynn M. Lemoine","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I92446798","display_name":"Colorado State University","ror":"https://ror.org/03k1gpj17","country_code":"US","type":"education","lineage":["https://openalex.org/I92446798"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lynn M. Lemoine","raw_affiliation_strings":["Department of Chemistry, Colorado State University Fort Collins, Colorado 80523-1872 Bayer Corporation, 400 Morgan Lane West Haven, Connecticut 06516-4175"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Colorado State University Fort Collins, Colorado 80523-1872 Bayer Corporation, 400 Morgan Lane West Haven, Connecticut 06516-4175","institution_ids":["https://openalex.org/I92446798"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010894224","display_name":"Susan Pleasic\u2010Williams","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I92446798","display_name":"Colorado State University","ror":"https://ror.org/03k1gpj17","country_code":"US","type":"education","lineage":["https://openalex.org/I92446798"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan Pleasic-Williams","raw_affiliation_strings":["Department of Chemistry, Colorado State University Fort Collins, Colorado 80523-1872 Bayer Corporation, 400 Morgan Lane West Haven, Connecticut 06516-4175"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Colorado State University Fort Collins, Colorado 80523-1872 Bayer Corporation, 400 Morgan Lane West Haven, Connecticut 06516-4175","institution_ids":["https://openalex.org/I92446798"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079618655","display_name":"Mark T. Vandenberg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I92446798","display_name":"Colorado State University","ror":"https://ror.org/03k1gpj17","country_code":"US","type":"education","lineage":["https://openalex.org/I92446798"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark Vandenberg","raw_affiliation_strings":["Department of Chemistry, Colorado State University Fort Collins, Colorado 80523-1872 Bayer Corporation, 400 Morgan Lane West Haven, Connecticut 06516-4175"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Colorado State University Fort Collins, Colorado 80523-1872 Bayer Corporation, 400 Morgan Lane West Haven, Connecticut 06516-4175","institution_ids":["https://openalex.org/I92446798"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043869683","display_name":"Anthony J. Rossomando","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I92446798","display_name":"Colorado State University","ror":"https://ror.org/03k1gpj17","country_code":"US","type":"education","lineage":["https://openalex.org/I92446798"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anthony J. Rossomando","raw_affiliation_strings":["Department of Chemistry, Colorado State University Fort Collins, Colorado 80523-1872 Bayer Corporation, 400 Morgan Lane West Haven, Connecticut 06516-4175"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Colorado State University Fort Collins, Colorado 80523-1872 Bayer Corporation, 400 Morgan Lane West Haven, Connecticut 06516-4175","institution_ids":["https://openalex.org/I92446798"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015570446","display_name":"Laurel J. Sweet","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I92446798","display_name":"Colorado State University","ror":"https://ror.org/03k1gpj17","country_code":"US","type":"education","lineage":["https://openalex.org/I92446798"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laurel J. Sweet","raw_affiliation_strings":["Department of Chemistry, Colorado State University Fort Collins, Colorado 80523-1872 Bayer Corporation, 400 Morgan Lane West Haven, Connecticut 06516-4175"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Colorado State University Fort Collins, Colorado 80523-1872 Bayer Corporation, 400 Morgan Lane West Haven, Connecticut 06516-4175","institution_ids":["https://openalex.org/I92446798"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I92446798"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":6.0255,"has_fulltext":false,"cited_by_count":97,"citation_normalized_percentile":{"value":0.97579124,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"119","issue":"23","first_page":"5447","last_page":"5448"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12136","display_name":"Vanadium and Halogenation Chemistry","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1604","display_name":"Inorganic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12136","display_name":"Vanadium and Halogenation Chemistry","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1604","display_name":"Inorganic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10163","display_name":"Metal complexes synthesis and properties","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10274","display_name":"Heterocyclic Compound Synthesis and Bioactivity","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/insulin-like-activity","display_name":"insulin-like activity","score":0.7440000176429749},{"id":"https://openalex.org/keywords/vanadium-complexes","display_name":"vanadium complexes","score":0.5929999947547913},{"id":"https://openalex.org/keywords/imidazole-ligands","display_name":"imidazole ligands","score":0.8209999799728394},{"id":"https://openalex.org/keywords/glucose-uptake","display_name":"glucose uptake","score":0.3840000033378601},{"id":"https://openalex.org/keywords/antidiabetic-drugs","display_name":"antidiabetic drugs","score":0.6179999709129333},{"id":"https://openalex.org/keywords/crystal-structure","display_name":"crystal structure","score":0.6320000290870667},{"id":"https://openalex.org/keywords/coordination-chemistry","display_name":"coordination chemistry","score":0.6629999876022339},{"id":"https://openalex.org/keywords/metalloporphyrins","display_name":"metalloporphyrins","score":0.5839999914169312},{"id":"https://openalex.org/keywords/vanadium-porphyrins","display_name":"vanadium porphyrins","score":0.41499999165534973},{"id":"https://openalex.org/keywords/metalloproteins","display_name":"metalloproteins","score":0.4020000100135803},{"id":"https://openalex.org/keywords/metalloenzymes","display_name":"metalloenzymes","score":0.5360000133514404}],"concepts":[{"id":"https://openalex.org/C2778805511","wikidata":"https://www.wikidata.org/wiki/Q1713","display_name":"Citation","level":2,"score":0.616514265537262},{"id":"https://openalex.org/C161191863","wikidata":"https://www.wikidata.org/wiki/Q199655","display_name":"Library science","level":1,"score":0.5500869750976562},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.44239935278892517},{"id":"https://openalex.org/C2777496998","wikidata":"https://www.wikidata.org/wiki/Q1536587","display_name":"Miller","level":2,"score":0.41828519105911255},{"id":"https://openalex.org/C52119013","wikidata":"https://www.wikidata.org/wiki/Q50637","display_name":"Art history","level":1,"score":0.37570491433143616},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.3288993835449219},{"id":"https://openalex.org/C142362112","wikidata":"https://www.wikidata.org/wiki/Q735","display_name":"Art","level":0,"score":0.2834343910217285},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.08927363157272339},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1021/ja9701671","doi":"https://doi.org/10.1021/ja9701671","is_oa":false,"landing_page_url":"https://doi.org/10.1021/ja9701671","pdf_url":null,"source":{"id":"https://openalex.org/S111155417","display_name":"Journal of the American Chemical Society","issn_l":"0002-7863","issn":["0002-7863","1520-5126","1943-2984"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Chemical Society","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W1487822346","https://openalex.org/W1559780175","https://openalex.org/W1568597946","https://openalex.org/W1971669331","https://openalex.org/W1972931383","https://openalex.org/W1975551090","https://openalex.org/W1981162349","https://openalex.org/W1984248071","https://openalex.org/W1987658587","https://openalex.org/W2010104820","https://openalex.org/W2015158469","https://openalex.org/W2018751358","https://openalex.org/W2020094209","https://openalex.org/W2027183157","https://openalex.org/W2032108914","https://openalex.org/W2046708063","https://openalex.org/W2048696671","https://openalex.org/W2058307795","https://openalex.org/W2060915816","https://openalex.org/W2064372582","https://openalex.org/W2077750566","https://openalex.org/W2082585947","https://openalex.org/W2094483041","https://openalex.org/W2122102685","https://openalex.org/W2125239101","https://openalex.org/W2167969877","https://openalex.org/W2952212061"],"related_works":["https://openalex.org/W4242177904","https://openalex.org/W2079489161","https://openalex.org/W7010614993","https://openalex.org/W4254989275","https://openalex.org/W1978734163","https://openalex.org/W1975551090","https://openalex.org/W2008942232","https://openalex.org/W2094483041","https://openalex.org/W2977765488","https://openalex.org/W2067605543"],"abstract_inverted_index":{"ADVERTISEMENT":[0],"RETURN":[1],"TO":[2],"ISSUEPREVCommunicationNEXTSynthesis,":[3],"Structure,":[4],"and":[5,40,117,122,151,195,212,228,230,246],"Biological":[6],"Activity":[7],"of":[8,47,107,142,168],"a":[9,165,172,185],"New":[10],"Insulinomimetic":[11],"Peroxovanadium":[12],"Compound:":[13],"Bisperoxovanadium":[14],"Imidazole":[15],"MonoanionDebbie":[16],"C.":[17],"Crans,":[18],"Anastasios":[19],"D.":[20],"Keramidas,":[21],"Helana":[22],"Hoover-Litty,":[23],"Oren":[24],"P.":[25],"Anderson,":[26],"Mary":[27],"M.":[28,31],"Miller,":[29],"Lynn":[30],"Lemoine,":[32],"Susan":[33],"Pleasic-Williams,":[34],"Mark":[35],"Vandenberg,":[36],"Anthony":[37],"J.":[38,42,67],"Rossomando,":[39],"Laurel":[41],"SweetView":[43],"Author":[44],"Information":[45,242,244],"Department":[46],"Chemistry,":[48],"Colorado":[49,54],"State":[50],"University":[51],"Fort":[52],"Collins,":[53],"80523-1872":[55],"Bayer":[56],"Corporation,":[57],"400":[58],"Morgan":[59],"Lane":[60],"West":[61],"Haven,":[62],"Connecticut":[63],"06516-4175":[64],"Cite":[65],"this:":[66],"Am.":[68],"Chem.":[69],"Soc.":[70],"1997,":[71],"119,":[72],"23,":[73],"5447\u20135448Publication":[74],"Date":[75],"(Web):June":[76],"11,":[77],"1997Publication":[78],"History":[79],"Received21":[80],"January":[81],"1997Published":[82,85],"online11":[83],"June":[84,88],"inissue":[86],"1":[87],"1997https://pubs.acs.org/doi/10.1021/ja9701671https://doi.org/10.1021/ja9701671rapid-communicationACS":[89],"PublicationsCopyright":[90],"\u00a9":[91],"1997":[92],"American":[93],"Chemical":[94],"SocietyRequest":[95],"reuse":[96],"permissionsArticle":[97],"Views686Altmetric-Citations86LEARN":[98],"ABOUT":[99],"THESE":[100],"METRICSArticle":[101],"Views":[102],"are":[103,126,139],"the":[104,135,140,169,180,193,196,201,208,214],"COUNTER-compliant":[105],"sum":[106],"full":[108],"text":[109],"article":[110,174],"downloads":[111],"since":[112],"November":[113],"2008":[114],"(both":[115],"PDF":[116],"HTML)":[118],"across":[119],"all":[120],"institutions":[121],"individuals.":[123],"These":[124],"metrics":[125],"regularly":[127],"updated":[128,152],"to":[129,134],"reflect":[130],"usage":[131],"leading":[132],"up":[133],"last":[136],"few":[137],"days.Citations":[138],"number":[141],"other":[143],"articles":[144],"citing":[145],"this":[146],"article,":[147],"calculated":[148],"by":[149],"Crossref":[150,158],"daily.":[153],"Find":[154,204],"more":[155,205],"information":[156,206],"about":[157,192],"citation":[159],"counts.The":[160],"Altmetric":[161,209],"Attention":[162,210],"Score":[163,211],"is":[164,216],"quantitative":[166],"measure":[167],"attention":[170],"that":[171],"research":[173],"has":[175],"received":[176],"online.":[177],"Clicking":[178],"on":[179,207],"donut":[181],"icon":[182],"will":[183],"load":[184],"page":[186],"at":[187],"altmetric.com":[188],"with":[189,224],"additional":[190],"details":[191],"score":[194,215],"social":[197],"media":[198],"presence":[199],"for":[200],"given":[202],"article.":[203],"how":[213],"calculated.":[217],"Share":[218,233],"Add":[219],"toView":[220],"InAdd":[221],"Full":[222],"Text":[223],"ReferenceAdd":[225],"Description":[226],"ExportRISCitationCitation":[227],"abstractCitation":[229],"referencesMore":[231],"Options":[232],"onFacebookTwitterWechatLinked":[234],"InRedditEmail":[235],"Other":[236],"access":[237],"optionsGet":[238],"e-AlertscloseSupporting":[239],"Info":[240],"(1)\u00bbSupporting":[241],"Supporting":[243],"SUBJECTS:Carbohydrates,Imidazoles,Peptides":[245],"proteins,Receptors,Vanadium":[247],"Get":[248],"e-Alerts":[249]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}