{"id":"https://openalex.org/W2093370261","doi":"https://doi.org/10.1016/j.jbiomech.2010.11.002","title":"Evaluation of the influence of growth medium composition on cell elasticity","display_name":"Evaluation of the influence of growth medium composition on cell elasticity","publication_year":2010,"publication_date":"2010-11-25","ids":{"openalex":"https://openalex.org/W2093370261","doi":"https://doi.org/10.1016/j.jbiomech.2010.11.002","mag":"2093370261","pmid":"https://pubmed.ncbi.nlm.nih.gov/21109247"},"language":"en","primary_location":{"id":"doi:10.1016/j.jbiomech.2010.11.002","doi":"https://doi.org/10.1016/j.jbiomech.2010.11.002","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jbiomech.2010.11.002","pdf_url":null,"source":{"id":"https://openalex.org/S181675524","display_name":"Journal of Biomechanics","issn_l":"0021-9290","issn":["0021-9290","1873-2380"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomechanics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063683471","display_name":"Mehdi Nikkhah","orcid":"https://orcid.org/0000-0001-5970-7666","observed_orcids":["https://orcid.org/0000-0001-5970-7666","https://orcid.org/0000-0003-3373-5022"]},"institutions":[{"id":"https://openalex.org/I859038795","display_name":"Virginia Tech","ror":"https://ror.org/02smfhw86","country_code":"US","type":"education","lineage":["https://openalex.org/I859038795"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mehdi Nikkhah","raw_affiliation_strings":["Department of Mechanical Engineering, Virginia Tech, Blacksburg, VA 24061, USA. mnikkhah@vt.edu","Department of Mechanical Engineering, Virginia Tech, Blacksburg, VA 24061, USA","VT MEMS Lab, The Bradley Department of Electrical and Computer Engineering, Virginia Tech, 302 Whittemore Hall (MC 0111), Blacksburg, VA 24061, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering, Virginia Tech, Blacksburg, VA 24061, USA. mnikkhah@vt.edu","institution_ids":["https://openalex.org/I859038795"]},{"raw_affiliation_string":"Department of Mechanical Engineering, Virginia Tech, Blacksburg, VA 24061, USA","institution_ids":["https://openalex.org/I859038795"]},{"raw_affiliation_string":"VT MEMS Lab, The Bradley Department of Electrical and Computer Engineering, Virginia Tech, 302 Whittemore Hall (MC 0111), Blacksburg, VA 24061, USA","institution_ids":["https://openalex.org/I859038795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081300060","display_name":"Jeannine S. Strobl","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I859038795","display_name":"Virginia Tech","ror":"https://ror.org/02smfhw86","country_code":"US","type":"education","lineage":["https://openalex.org/I859038795"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeannine S. Strobl","raw_affiliation_strings":["VT MEMS Lab, The Bradley Department of Electrical and Computer Engineering, Virginia Tech, 302 Whittemore Hall (MC 0111), Blacksburg, VA 24061, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"VT MEMS Lab, The Bradley Department of Electrical and Computer Engineering, Virginia Tech, 302 Whittemore Hall (MC 0111), Blacksburg, VA 24061, USA","institution_ids":["https://openalex.org/I859038795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016579574","display_name":"Eva M. Schmelz","orcid":"https://orcid.org/0000-0002-3374-5266","observed_orcids":["https://orcid.org/0000-0002-3374-5266"]},"institutions":[{"id":"https://openalex.org/I859038795","display_name":"Virginia Tech","ror":"https://ror.org/02smfhw86","country_code":"US","type":"education","lineage":["https://openalex.org/I859038795"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eva M. Schmelz","raw_affiliation_strings":["Department of Human Nutrition, Foods and Exercise, Virginia Tech, Blacksburg, VA 24061, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Human Nutrition, Foods and Exercise, Virginia Tech, Blacksburg, VA 24061, USA","institution_ids":["https://openalex.org/I859038795"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052698723","display_name":"Masoud Agah","orcid":"https://orcid.org/0000-0001-6117-4539","observed_orcids":["https://orcid.org/0000-0001-6117-4539"]},"institutions":[{"id":"https://openalex.org/I859038795","display_name":"Virginia Tech","ror":"https://ror.org/02smfhw86","country_code":"US","type":"education","lineage":["https://openalex.org/I859038795"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Masoud Agah","raw_affiliation_strings":["VT MEMS Lab, The Bradley Department of Electrical and Computer Engineering, Virginia Tech, 302 Whittemore Hall (MC 0111), Blacksburg, VA 24061, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"VT MEMS Lab, The Bradley Department of Electrical and Computer Engineering, Virginia Tech, 302 Whittemore Hall (MC 0111), Blacksburg, VA 24061, USA","institution_ids":["https://openalex.org/I859038795"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5052698723"],"corresponding_institution_ids":["https://openalex.org/I859038795"],"apc_list":{"value":3650,"currency":"USD","value_usd":3650},"apc_paid":null,"fwci":1.3979,"has_fulltext":false,"cited_by_count":103,"citation_normalized_percentile":{"value":0.78459757,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":100},"biblio":{"volume":"44","issue":"4","first_page":"762","last_page":"766"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10923","display_name":"Force Microscopy Techniques and Applications","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/3107","display_name":"Atomic and Molecular Physics, and Optics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11366","display_name":"Elasticity and Material Modeling","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cell-elasticity","display_name":"cell elasticity","score":0.9850000143051147},{"id":"https://openalex.org/keywords/young-s-modulus","display_name":"Young's modulus","score":0.8870000243186951},{"id":"https://openalex.org/keywords/culture-medium-composition","display_name":"culture medium composition","score":0.9350000023841858},{"id":"https://openalex.org/keywords/breast-cancer-cells","display_name":"breast cancer cells","score":0.7720000147819519},{"id":"https://openalex.org/keywords/mcf10a","display_name":"MCF10A","score":0.8709999918937683},{"id":"https://openalex.org/keywords/mda-mb-231-cells","display_name":"MDA-MB-231 cells","score":1.0},{"id":"https://openalex.org/keywords/serum-levels","display_name":"serum concentration","score":0.7559999823570251},{"id":"https://openalex.org/keywords/epidermal-growth-factor","display_name":"epidermal growth factor","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cholera-toxin","display_name":"cholera toxin","score":0.902999997138977},{"id":"https://openalex.org/keywords/insulin","display_name":"insulin","score":0.9559999704360962},{"id":"https://openalex.org/keywords/cortisol","display_name":"cortisol","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cell-mechanics","display_name":"cell mechanics","score":0.8450000286102295},{"id":"https://openalex.org/keywords/tumor-markers","display_name":"tumor markers","score":0.6830000281333923}],"concepts":[{"id":"https://openalex.org/C121854251","wikidata":"https://www.wikidata.org/wiki/Q62932","display_name":"Elasticity (physics)","level":2,"score":0.5512996315956116},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5457266569137573},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.5396708250045776},{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.495733380317688},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.47985905408859253},{"id":"https://openalex.org/C2776362946","wikidata":"https://www.wikidata.org/wiki/Q424374","display_name":"Epidermal growth factor","level":3,"score":0.45341312885284424},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3533567190170288},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.32129424810409546},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2539430260658264},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2535814642906189},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.23683586716651917},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2142494022846222},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.1952793300151825},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.07711681723594666},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.06642013788223267}],"mesh":[{"descriptor_ui":"D001940","descriptor_name":"Breast","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D001940","descriptor_name":"Breast","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003470","descriptor_name":"Culture Media","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055119","descriptor_name":"Elastic Modulus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jbiomech.2010.11.002","doi":"https://doi.org/10.1016/j.jbiomech.2010.11.002","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jbiomech.2010.11.002","pdf_url":null,"source":{"id":"https://openalex.org/S181675524","display_name":"Journal of Biomechanics","issn_l":"0021-9290","issn":["0021-9290","1873-2380"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomechanics","raw_type":"journal-article"},{"id":"pmid:21109247","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21109247","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of biomechanics","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.428600013256073}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/10","display_name":"Reduced inequalities","score":0.6499999761581421}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5068483163","display_name":"IDR: A Cancer Sensor-on-a-Chip Using Integrated Biomechanical and Bioimpedance Cell Signatures","funder_award_id":"0925945","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320337392","display_name":"Division of Electrical, Communications and Cyber Systems","ror":"https://ror.org/01krpsy48"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W1516531545","https://openalex.org/W1964242194","https://openalex.org/W1964484998","https://openalex.org/W1964560722","https://openalex.org/W1968369580","https://openalex.org/W1979272419","https://openalex.org/W1993738751","https://openalex.org/W1994109845","https://openalex.org/W2001998785","https://openalex.org/W2006073003","https://openalex.org/W2008816730","https://openalex.org/W2008873300","https://openalex.org/W2022243571","https://openalex.org/W2026369829","https://openalex.org/W2030642623","https://openalex.org/W2044862408","https://openalex.org/W2061180610","https://openalex.org/W2092412094","https://openalex.org/W2092994838","https://openalex.org/W2130172628","https://openalex.org/W2150102283","https://openalex.org/W2409772426","https://openalex.org/W2591181672","https://openalex.org/W3014141305","https://openalex.org/W6630794695"],"related_works":["https://openalex.org/W2030642623","https://openalex.org/W4242499883","https://openalex.org/W2554014482","https://openalex.org/W2912199670","https://openalex.org/W4408891554","https://openalex.org/W7048175093","https://openalex.org/W7127919574","https://openalex.org/W2604749772","https://openalex.org/W129111912","https://openalex.org/W2035870646"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":11},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":15},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}