{"id":"https://openalex.org/W2092996089","doi":"https://doi.org/10.1016/j.ijid.2008.05.1190","title":"Prevalence and Predictors of Methicillin-Resistant Staphylococcus aureus (MRSA) and Extended-Spectrum Beta-Lactamase (ESBL) Gram-Negative Bacteria at Hospital Presentation in Singapore","display_name":"Prevalence and Predictors of Methicillin-Resistant Staphylococcus aureus (MRSA) and Extended-Spectrum Beta-Lactamase (ESBL) Gram-Negative Bacteria at Hospital Presentation in Singapore","publication_year":2008,"publication_date":"2008-12-01","ids":{"openalex":"https://openalex.org/W2092996089","doi":"https://doi.org/10.1016/j.ijid.2008.05.1190","mag":"2092996089"},"language":"en","primary_location":{"id":"doi:10.1016/j.ijid.2008.05.1190","doi":"https://doi.org/10.1016/j.ijid.2008.05.1190","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ijid.2008.05.1190","pdf_url":"http://www.ijidonline.com/article/S1201971208013209/pdf","source":{"id":"https://openalex.org/S35071406","display_name":"International Journal of Infectious Diseases","issn_l":"1201-9712","issn":["1201-9712","1878-3511"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Infectious Diseases","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://www.ijidonline.com/article/S1201971208013209/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087952323","display_name":"Surinder Pada","orcid":"https://orcid.org/0000-0002-2384-376X","observed_orcids":["https://orcid.org/0000-0002-2384-376X"]},"institutions":[{"id":"https://openalex.org/I2802408685","display_name":"Tan Tock Seng Hospital","ror":"https://ror.org/032d59j24","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2802408685"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"S. Pada","raw_affiliation_strings":["Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore","institution_ids":["https://openalex.org/I2802408685"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039929987","display_name":"David Chien Lye","orcid":"https://orcid.org/0000-0003-0324-0205","observed_orcids":["https://orcid.org/0000-0003-0324-0205"]},"institutions":[{"id":"https://openalex.org/I2802408685","display_name":"Tan Tock Seng Hospital","ror":"https://ror.org/032d59j24","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2802408685"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"D. Lye","raw_affiliation_strings":["Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore","institution_ids":["https://openalex.org/I2802408685"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073543838","display_name":"Prabha Krishnan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802408685","display_name":"Tan Tock Seng Hospital","ror":"https://ror.org/032d59j24","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2802408685"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"P. Krishnan","raw_affiliation_strings":["Laboratory Medicine, Tan Tock Seng Hospital, Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory Medicine, Tan Tock Seng Hospital, Singapore, Singapore","institution_ids":["https://openalex.org/I2802408685"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008971323","display_name":"Joey Chan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802408685","display_name":"Tan Tock Seng Hospital","ror":"https://ror.org/032d59j24","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2802408685"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"J. Chan","raw_affiliation_strings":["Laboratory Medicine, Tan Tock Seng Hospital, Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory Medicine, Tan Tock Seng Hospital, Singapore, Singapore","institution_ids":["https://openalex.org/I2802408685"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111586515","display_name":"S P Chan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802408685","display_name":"Tan Tock Seng Hospital","ror":"https://ror.org/032d59j24","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2802408685"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"S.P. Chan","raw_affiliation_strings":["Clinical Research Unit, Tan Tock Seng Hospital, Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Research Unit, Tan Tock Seng Hospital, Singapore, Singapore","institution_ids":["https://openalex.org/I2802408685"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013840458","display_name":"Gregory Cham","orcid":"https://orcid.org/0000-0002-1780-0798","observed_orcids":["https://orcid.org/0000-0002-1780-0798"]},"institutions":[{"id":"https://openalex.org/I2802408685","display_name":"Tan Tock Seng Hospital","ror":"https://ror.org/032d59j24","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2802408685"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"G. Cham","raw_affiliation_strings":["Emergency Medicine, Tan Tock Seng Hospital, Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Emergency Medicine, Tan Tock Seng Hospital, Singapore, Singapore","institution_ids":["https://openalex.org/I2802408685"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085958612","display_name":"Brenda Sze Peng Ang","orcid":"https://orcid.org/0000-0003-3102-8287","observed_orcids":["https://orcid.org/0000-0003-3102-8287"]},"institutions":[{"id":"https://openalex.org/I2802408685","display_name":"Tan Tock Seng Hospital","ror":"https://ror.org/032d59j24","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2802408685"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"B.S. Ang","raw_affiliation_strings":["Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore","institution_ids":["https://openalex.org/I2802408685"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035691657","display_name":"Yee\u2010Sin Leo","orcid":"https://orcid.org/0000-0003-4978-5825","observed_orcids":["https://orcid.org/0000-0003-4978-5825"]},"institutions":[{"id":"https://openalex.org/I2802408685","display_name":"Tan Tock Seng Hospital","ror":"https://ror.org/032d59j24","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2802408685"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Y.S. Leo","raw_affiliation_strings":["Tan Tock Seng Hospital, Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tan Tock Seng Hospital, Singapore, Singapore","institution_ids":["https://openalex.org/I2802408685"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5087952323"],"corresponding_institution_ids":["https://openalex.org/I2802408685"],"apc_list":{"value":2900,"currency":"USD","value_usd":2900},"apc_paid":{"value":2900,"currency":"USD","value_usd":2900},"fwci":0.2218,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.58270899,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"12","issue":null,"first_page":"e449","last_page":"e450"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10195","display_name":"Antimicrobial Resistance in Staphylococcus","score":0.9262999892234802,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10195","display_name":"Antimicrobial Resistance in Staphylococcus","score":0.9262999892234802,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.039900001138448715,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10897","display_name":"Antibiotic Use and Resistance","score":0.014600000344216824,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/methicillin-resistant-staphylococcus-aureus","display_name":"methicillin-resistant Staphylococcus aureus","score":0.9980000257492065},{"id":"https://openalex.org/keywords/extended-spectrum-beta-lactamase","display_name":"extended-spectrum beta-lactamase","score":0.949999988079071},{"id":"https://openalex.org/keywords/gram-negative-bacteria","display_name":"Gram-negative bacteria","score":0.7329999804496765},{"id":"https://openalex.org/keywords/vancomycin-resistant-enterococci","display_name":"vancomycin-resistant enterococci","score":0.9139999747276306},{"id":"https://openalex.org/keywords/mrsa-colonization","display_name":"MRSA colonization","score":0.7760000228881836},{"id":"https://openalex.org/keywords/nosocomial-infections","display_name":"nosocomial infections","score":0.5360000133514404},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.5709999799728394},{"id":"https://openalex.org/keywords/emergency-department-patients","display_name":"emergency department patients","score":0.6290000081062317},{"id":"https://openalex.org/keywords/singapore","display_name":"Singapore","score":0.47999998927116394},{"id":"https://openalex.org/keywords/hand-hygiene","display_name":"hand hygiene","score":0.6639999747276306},{"id":"https://openalex.org/keywords/prudent-antibiotic-prescribing","display_name":"prudent antibiotic prescribing","score":0.9490000009536743},{"id":"https://openalex.org/keywords/nursing-home-residents","display_name":"nursing home residents","score":0.46299999952316284}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8362045288085938},{"id":"https://openalex.org/C2777052132","wikidata":"https://www.wikidata.org/wiki/Q595158","display_name":"Methicillin-resistant Staphylococcus aureus","level":4,"score":0.6497887372970581},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5199916958808899},{"id":"https://openalex.org/C105878827","wikidata":"https://www.wikidata.org/wiki/Q2041929","display_name":"Colonisation","level":3,"score":0.5064693689346313},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.4753170609474182},{"id":"https://openalex.org/C2781414143","wikidata":"https://www.wikidata.org/wiki/Q411377","display_name":"Linezolid","level":5,"score":0.4428812265396118},{"id":"https://openalex.org/C3020110884","wikidata":"https://www.wikidata.org/wiki/Q695416","display_name":"Outpatient clinic","level":2,"score":0.4386186897754669},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.4038088321685791},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.35122764110565186},{"id":"https://openalex.org/C2778980435","wikidata":"https://www.wikidata.org/wiki/Q424027","display_name":"Vancomycin","level":4,"score":0.2582695484161377},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.241784930229187},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.0},{"id":"https://openalex.org/C2776927270","wikidata":"https://www.wikidata.org/wiki/Q815962","display_name":"Colonization","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.ijid.2008.05.1190","doi":"https://doi.org/10.1016/j.ijid.2008.05.1190","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ijid.2008.05.1190","pdf_url":"http://www.ijidonline.com/article/S1201971208013209/pdf","source":{"id":"https://openalex.org/S35071406","display_name":"International Journal of Infectious Diseases","issn_l":"1201-9712","issn":["1201-9712","1878-3511"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Infectious Diseases","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.ijid.2008.05.1190","doi":"https://doi.org/10.1016/j.ijid.2008.05.1190","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ijid.2008.05.1190","pdf_url":"http://www.ijidonline.com/article/S1201971208013209/pdf","source":{"id":"https://openalex.org/S35071406","display_name":"International Journal of Infectious Diseases","issn_l":"1201-9712","issn":["1201-9712","1878-3511"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Infectious Diseases","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2092996089.pdf","grobid_xml":"https://content.openalex.org/works/W2092996089.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2054678267","https://openalex.org/W2057712738","https://openalex.org/W2216053028","https://openalex.org/W2133188099","https://openalex.org/W2320928324","https://openalex.org/W2337610504","https://openalex.org/W996845022","https://openalex.org/W2403109780","https://openalex.org/W2393019289","https://openalex.org/W2060884707"],"abstract_inverted_index":{"Background:":[0],"Methicillin":[1],"resistance":[2],"occurs":[3],"in":[4,12,49,166,176,194,213,273],"66%":[5],"of":[6,39,62,137,227,243],"nosocomial":[7,267,289],"Staphylococcus":[8],"aureus":[9],"while":[10,219,269],"ESBL":[11],"21%":[13],"Escherichia":[14],"coli":[15],"and":[16,25,37,44,71,84,115,118,124,128,142,158,171,178,187,197,215,242,262,292],"51%":[17],"Klebsiella":[18],"pneumoniae":[19],"at":[20],"our":[21,53],"institution.":[22],"Community-onset":[23],"MRSA":[24,210,228,261,290],"vancomycin-resistant":[26],"enterococci":[27],"(VRE)":[28],"occur":[29],"locally.":[30],"We":[31],"wish":[32],"to":[33,65,79,91,105,133,182,287],"determine":[34,134],"the":[35,274],"prevalence":[36],"predictors":[38,136],"colonisation":[40,138,211,229,246,264,283],"by":[41,75,139,204],"MRSA,":[42,82,140],"VRE":[43,83,141,263],"ESBL-positive":[45,85,143,216,244,281],"Gram-negative":[46],"bacilli":[47],"(GNB)":[48],"patients":[50,59,148],"admitted":[51],"from":[52],"Emergency":[54],"Department.":[55],"Methods:":[56],"All":[57],"adult":[58],">16":[60],"years":[61],"age":[63,151],"consenting":[64],"participation":[66],"underwent":[67],"nasal,":[68],"axilla,":[69],"groin":[70],"rectal":[72],"swabs,":[73],"processed":[74],"validated":[76],"published":[77],"methods":[78],"screen":[80],"for":[81,278],"GNB.":[86,144],"A":[87],"questionnaire":[88],"was":[89,152,174,202,230,247],"used":[90],"record":[92],"age,":[93],"gender,":[94],"co-morbidity,":[95],"nursing":[96,159],"home":[97,160],"residence,":[98],"contact":[99],"with":[100],"healthcare":[101],"workers;":[102],"hospitalisation,":[103],"visit":[104],"hospital":[106,183],"outpatient,":[107,184],"general":[108,188],"practitioners":[109,189],"or":[110],"government":[111,185],"polyclinics":[112,186],"within":[113,122,169,190,206,232,250],"3":[114,125,170,208,233],"12":[116,172,191],"months;":[117],"oral":[119,248,270],"antibiotic":[120,201,249,271,294],"use":[121,272],"1":[123,251],"months.":[126,209],"Univariate":[127],"multivariate":[129],"analysis":[130],"were":[131],"performed":[132],"independent":[135,225],"Results:":[145],"Of":[146],"1003":[147],"recruited,":[149],"mean":[150],"47":[153],"years;":[154],"male":[155],"comprised":[156],"65%":[157],"residents":[161],"2.2%.":[162],"Diabetes":[163],"mellitus":[164],"occurred":[165,193,212],"21%.":[167],"Hospitalisation":[168],"months":[173,192,234],"noted":[175],"17%":[177],"27%":[179],"respectively.":[180,199],"Visit":[181],"48%,":[195],"44%":[196],"48%":[198],"Oral":[200],"taken":[203],"28%":[205],"last":[207],"1.8%":[214],"GNB":[217,245,282],"12%":[218],"none":[220],"had":[221],"VRE.":[222],"The":[223],"only":[224],"predictor":[226],"hospitalisation":[231],"(adjusted":[235,253],"odds":[236,254],"ratio":[237,255],"3.9,":[238],"p":[239,257],"=":[240,258],"0.04)":[241],"month":[252],"1.9,":[256],"0.02).":[259],"Conclusions:":[260],"remain":[265],"a":[266],"problem":[268],"community":[275],"has":[276],"selected":[277],"alarmingly":[279],"high":[280],"rate.":[284],"Hand":[285],"hygiene":[286],"control":[288],"transmission":[291],"prudent":[293],"prescribing":[295],"are":[296],"needed.":[297]},"counts_by_year":[{"year":2016,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}