{"id":"https://openalex.org/W2092945162","doi":"https://doi.org/10.1177/34.2.3511141","title":"Immunohistochemical localization of pancreatic secretory trypsin inhibitor in fetal and adult pancreatic and extrapancreatic tissues.","display_name":"Immunohistochemical localization of pancreatic secretory trypsin inhibitor in fetal and adult pancreatic and extrapancreatic tissues.","publication_year":1986,"publication_date":"1986-02-01","ids":{"openalex":"https://openalex.org/W2092945162","doi":"https://doi.org/10.1177/34.2.3511141","mag":"2092945162","pmid":"https://pubmed.ncbi.nlm.nih.gov/3511141"},"language":"en","primary_location":{"id":"doi:10.1177/34.2.3511141","doi":"https://doi.org/10.1177/34.2.3511141","is_oa":false,"landing_page_url":"https://doi.org/10.1177/34.2.3511141","pdf_url":null,"source":{"id":"https://openalex.org/S30841621","display_name":"Journal of Histochemistry & Cytochemistry","issn_l":"0022-1554","issn":["0022-1554","1551-5044"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Histochemistry & Cytochemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005708651","display_name":"Masashi Fukayama","orcid":"https://orcid.org/0000-0002-0460-064X","observed_orcids":["https://orcid.org/0000-0002-0460-064X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Fukayama","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008182946","display_name":"Yukiko K Hayashi","orcid":"https://orcid.org/0000-0003-4043-1756","observed_orcids":["https://orcid.org/0000-0003-4043-1756"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y Hayashi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080200760","display_name":"Makoto Koike","orcid":"https://orcid.org/0000-0003-2386-5560","observed_orcids":["https://orcid.org/0000-0003-2386-5560"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Koike","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"M Ogawa","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Ogawa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5109314228","display_name":"G K\u014dsaki","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G Kosaki","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4400,"currency":"USD","value_usd":4400},"apc_paid":null,"fwci":1.4592,"has_fulltext":false,"cited_by_count":67,"citation_normalized_percentile":{"value":0.81964836,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"34","issue":"2","first_page":"227","last_page":"235"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.4494999945163727,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.4494999945163727,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10760","display_name":"Pancreatitis Pathology and Treatment","score":0.14790000021457672,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.13779999315738678,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pancreatic-secretory-trypsin-inhibitor","display_name":"pancreatic secretory trypsin inhibitor","score":0.996999979019165},{"id":"https://openalex.org/keywords/psti","display_name":"PstI","score":0.8500000238418579},{"id":"https://openalex.org/keywords/fetal-pancreas","display_name":"fetal pancreas","score":0.6819999814033508},{"id":"https://openalex.org/keywords/neuroepithelial-bodies","display_name":"neuroepithelial bodies","score":0.7699999809265137},{"id":"https://openalex.org/keywords/fetal-lung","display_name":"fetal lung","score":0.800000011920929},{"id":"https://openalex.org/keywords/duodenal-endocrine-cells","display_name":"duodenal endocrine cells","score":0.7770000100135803},{"id":"https://openalex.org/keywords/chronic-gastritis","display_name":"chronic gastritis","score":0.878000020980835},{"id":"https://openalex.org/keywords/carcinoid-tumor","display_name":"carcinoid tumor","score":0.9440000057220459},{"id":"https://openalex.org/keywords/gastrointestinal-inflammatory-diseases","display_name":"gastrointestinal inflammatory diseases","score":0.5479999780654907},{"id":"https://openalex.org/keywords/urinary-tract","display_name":"urinary tract","score":0.597000002861023},{"id":"https://openalex.org/keywords/gallbladder","display_name":"gallbladder","score":0.5400000214576721}],"concepts":[{"id":"https://openalex.org/C2778764654","wikidata":"https://www.wikidata.org/wiki/Q9618","display_name":"Pancreas","level":2,"score":0.6786689162254333},{"id":"https://openalex.org/C2780397633","wikidata":"https://www.wikidata.org/wiki/Q6090491","display_name":"PstI","level":4,"score":0.647819995880127},{"id":"https://openalex.org/C103395026","wikidata":"https://www.wikidata.org/wiki/Q5380231","display_name":"Enteroendocrine cell","level":4,"score":0.5608298778533936},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5547069907188416},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5320677757263184},{"id":"https://openalex.org/C2780512811","wikidata":"https://www.wikidata.org/wiki/Q11829360","display_name":"Gastrointestinal tract","level":2,"score":0.5284899473190308},{"id":"https://openalex.org/C2779422922","wikidata":"https://www.wikidata.org/wiki/Q1029907","display_name":"Stomach","level":2,"score":0.5059341788291931},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4885302782058716},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.48476237058639526},{"id":"https://openalex.org/C2776809568","wikidata":"https://www.wikidata.org/wiki/Q134955","display_name":"Duodenum","level":2,"score":0.47775545716285706},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.45509976148605347},{"id":"https://openalex.org/C46699223","wikidata":"https://www.wikidata.org/wiki/Q11078","display_name":"Endocrine system","level":3,"score":0.313098669052124},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.24076136946678162},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.10494741797447205},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.08954161405563354},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.0},{"id":"https://openalex.org/C128319531","wikidata":"https://www.wikidata.org/wiki/Q219715","display_name":"Restriction enzyme","level":3,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004064","descriptor_name":"Digestive System","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005333","descriptor_name":"Fetus","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D005756","descriptor_name":"Gastritis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006651","descriptor_name":"Histocytochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007124","descriptor_name":"Immunoenzyme Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010179","descriptor_name":"Pancreas","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012137","descriptor_name":"Respiratory System","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D013363","descriptor_name":"Submandibular Gland","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D014359","descriptor_name":"Trypsin Inhibitor, Kazal Pancreatic","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D014359","descriptor_name":"Trypsin Inhibitor, Kazal Pancreatic","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D014361","descriptor_name":"Trypsin Inhibitors","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D014566","descriptor_name":"Urogenital System","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1177/34.2.3511141","doi":"https://doi.org/10.1177/34.2.3511141","is_oa":false,"landing_page_url":"https://doi.org/10.1177/34.2.3511141","pdf_url":null,"source":{"id":"https://openalex.org/S30841621","display_name":"Journal of Histochemistry & Cytochemistry","issn_l":"0022-1554","issn":["0022-1554","1551-5044"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Histochemistry & Cytochemistry","raw_type":"journal-article"},{"id":"pmid:3511141","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3511141","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society","raw_type":"Journal Article"},{"id":"mag:2347057073","doi":null,"is_oa":false,"landing_page_url":"http://ci.nii.ac.jp/naid/500000031493","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1522731119","https://openalex.org/W1585589022","https://openalex.org/W1965379407","https://openalex.org/W1973765441","https://openalex.org/W1977265341","https://openalex.org/W2018961949","https://openalex.org/W2023887855","https://openalex.org/W2032568622","https://openalex.org/W2072523592","https://openalex.org/W2140422547","https://openalex.org/W2159012176","https://openalex.org/W2168597484","https://openalex.org/W2404295092","https://openalex.org/W2412583648","https://openalex.org/W2417065605","https://openalex.org/W2475202318","https://openalex.org/W2885364910"],"related_works":["https://openalex.org/W2010777770","https://openalex.org/W243997087","https://openalex.org/W2417065605","https://openalex.org/W883921939","https://openalex.org/W2401833640","https://openalex.org/W28206551","https://openalex.org/W2137021606","https://openalex.org/W2054267190","https://openalex.org/W2413903698","https://openalex.org/W2417979332"],"abstract_inverted_index":{"Pancreatic":[0],"secretory":[1,12,168],"trypsin":[2,13,169],"inhibitor":[3,14],"(PSTI)":[4],"has":[5],"been":[6],"thought":[7],"to":[8],"be":[9],"only":[10],"a":[11,149],"of":[15,22,50,90,121,127,171],"human":[16,41],"pancreas,":[17,42],"but":[18],"the":[19,31,69,78,131,172],"serum":[20],"content":[21],"immunoreactive":[23,34,128],"PSTI":[24,37,160],"is":[25],"elevated":[26],"without":[27],"pancreatic":[28],"disease.":[29],"Using":[30],"peroxidase-antiperoxidase":[32],"method,":[33],"cells":[35,62,89,100,129,140],"for":[36],"were":[38,63,93,104,141],"found":[39,143],"in":[40,65,74,95,101,130,134,144,148],"stomach,":[43],"duodenum,":[44],"appendix,":[45],"colon":[46],"and":[47,53,58,73,81,84,106,147],"urinary":[48,82],"tract":[49],"both":[51],"fetus":[52],"adult,":[54],"adult":[55],"gall":[56],"bladder,":[57],"fetal":[59,66,91,102],"lung.":[60],"PSTI-immunoreactive":[61,88],"identified":[64],"pancreas":[67],"at":[68,77],"tenth":[70],"gestational":[71],"week,":[72],"extrapancreatic":[75],"tissues":[76,116],"sixteenth":[79],"(gastrointestinal":[80],"tract)":[83],"twentieth":[85],"weeks":[86],"(lung).":[87],"lung":[92],"present":[94],"neuroepithelial":[96],"bodies.":[97],"Strongly":[98],"positive":[99],"duodenum":[103],"argyrophilic":[105],"resembled":[107],"endocrine":[108,145],"cells.":[109],"Immunohistochemical":[110],"study":[111],"was":[112],"also":[113,142],"performed":[114],"on":[115],"associated":[117,152],"with":[118,136,153],"inflammatory":[119],"diseases":[120],"gastrointestinal":[122],"tract.":[123],"The":[124],"distribution":[125],"pattern":[126],"stomach":[132],"varied":[133],"accordance":[135],"chronic":[137],"gastritis.":[138,155],"Immunoreactive":[139],"micro-nests":[146],"carcinoid":[150],"tumor":[151],"fundic":[154],"These":[156],"results":[157],"suggest":[158],"that":[159],"may":[161],"play":[162],"some":[163],"physiological":[164],"role":[165],"other":[166],"than":[167],"inhibition":[170],"pancreas.":[173]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}