{"id":"https://openalex.org/W2092853142","doi":"https://doi.org/10.1016/j.reprotox.2008.05.054","title":"The antiandrogenic activity of pyrethroid pesticides cyfluthrin and \u03b2-cyfluthrin","display_name":"The antiandrogenic activity of pyrethroid pesticides cyfluthrin and \u03b2-cyfluthrin","publication_year":2008,"publication_date":"2008-05-16","ids":{"openalex":"https://openalex.org/W2092853142","doi":"https://doi.org/10.1016/j.reprotox.2008.05.054","mag":"2092853142","pmid":"https://pubmed.ncbi.nlm.nih.gov/18586453"},"language":"en","primary_location":{"id":"doi:10.1016/j.reprotox.2008.05.054","doi":"https://doi.org/10.1016/j.reprotox.2008.05.054","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.reprotox.2008.05.054","pdf_url":null,"source":{"id":"https://openalex.org/S1879512","display_name":"Reproductive Toxicology","issn_l":"0890-6238","issn":["0890-6238","1873-1708"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproductive Toxicology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100433214","display_name":"Jun Zhang","orcid":"https://orcid.org/0000-0002-9070-8701","observed_orcids":["https://orcid.org/0000-0002-9070-8701"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jun Zhang","raw_affiliation_strings":["Department of Toxicology, School of Medicine, Zhejiang University, 388 Yuhangtang Road, Hangzhou 310058, Zhejiang Province, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Toxicology, School of Medicine, Zhejiang University, 388 Yuhangtang Road, Hangzhou 310058, Zhejiang Province, PR China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012567718","display_name":"Wei Zhu","orcid":"https://orcid.org/0000-0002-9624-0724","observed_orcids":["https://orcid.org/0000-0002-9624-0724","https://orcid.org/0000-0001-7822-0095"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Zhu","raw_affiliation_strings":["Department of Toxicology, School of Medicine, Zhejiang University, 388 Yuhangtang Road, Hangzhou 310058, Zhejiang Province, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Toxicology, School of Medicine, Zhejiang University, 388 Yuhangtang Road, Hangzhou 310058, Zhejiang Province, PR China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037469844","display_name":"Yifan Zheng","orcid":"https://orcid.org/0000-0002-6997-735X","observed_orcids":["https://orcid.org/0000-0002-6997-735X"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yifan Zheng","raw_affiliation_strings":["Department of Toxicology, School of Medicine, Zhejiang University, 388 Yuhangtang Road, Hangzhou 310058, Zhejiang Province, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Toxicology, School of Medicine, Zhejiang University, 388 Yuhangtang Road, Hangzhou 310058, Zhejiang Province, PR China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108731091","display_name":"Jun Mo Yang","orcid":"https://orcid.org/0000-0002-0371-8814","observed_orcids":["https://orcid.org/0000-0002-0371-8814"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jun Yang","raw_affiliation_strings":["Department of Toxicology, School of Medicine, Zhejiang University, 388 Yuhangtang Road, Hangzhou 310058, Zhejiang Province, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Toxicology, School of Medicine, Zhejiang University, 388 Yuhangtang Road, Hangzhou 310058, Zhejiang Province, PR China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103272070","display_name":"Xinqiang Zhu","orcid":"https://orcid.org/0000-0002-9088-7906","observed_orcids":["https://orcid.org/0000-0002-9088-7906"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xinqiang Zhu","raw_affiliation_strings":["Department of Toxicology, School of Medicine, Zhejiang University, 388 Yuhangtang Road, Hangzhou 310058, Zhejiang Province, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Toxicology, School of Medicine, Zhejiang University, 388 Yuhangtang Road, Hangzhou 310058, Zhejiang Province, PR China","institution_ids":["https://openalex.org/I76130692"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5103272070"],"corresponding_institution_ids":["https://openalex.org/I76130692"],"apc_list":{"value":3800,"currency":"USD","value_usd":3800},"apc_paid":null,"fwci":1.9449,"has_fulltext":false,"cited_by_count":72,"citation_normalized_percentile":{"value":0.82017916,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"25","issue":"4","first_page":"491","last_page":"496"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10686","display_name":"Effects and risks of endocrine disrupting chemicals","score":0.8539999723434448,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10686","display_name":"Effects and risks of endocrine disrupting chemicals","score":0.8539999723434448,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10875","display_name":"Pesticide Exposure and Toxicity","score":0.1371999979019165,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cyfluthrin","display_name":"cyfluthrin","score":0.9100000262260437},{"id":"https://openalex.org/keywords/beta-cyfluthrin","display_name":"beta-cyfluthrin","score":0.9869999885559082},{"id":"https://openalex.org/keywords/pyrethroid-insecticides","display_name":"pyrethroid insecticides","score":0.9580000042915344},{"id":"https://openalex.org/keywords/antiandrogenic-activity","display_name":"antiandrogenic activity","score":0.968999981880188},{"id":"https://openalex.org/keywords/androgen-receptor-antagonism","display_name":"androgen receptor antagonism","score":0.9919999837875366},{"id":"https://openalex.org/keywords/hershberger-assay","display_name":"Hershberger assay","score":0.9549999833106995},{"id":"https://openalex.org/keywords/seminal-vesicle","display_name":"seminal vesicle","score":0.7250000238418579},{"id":"https://openalex.org/keywords/prostate","display_name":"prostate","score":0.6370000243186951},{"id":"https://openalex.org/keywords/cowper-s-gland","display_name":"Cowper's gland","score":0.8080000281333923},{"id":"https://openalex.org/keywords/bifenthrin","display_name":"bifenthrin","score":0.7519999742507935},{"id":"https://openalex.org/keywords/cypermethrin","display_name":"cypermethrin","score":0.8669999837875366},{"id":"https://openalex.org/keywords/permethrin","display_name":"permethrin","score":0.9750000238418579},{"id":"https://openalex.org/keywords/flutamide","display_name":"flutamide","score":0.7639999985694885},{"id":"https://openalex.org/keywords/endocrine-disruptors","display_name":"endocrine disruptors","score":0.7829999923706055}],"concepts":[{"id":"https://openalex.org/C2778635518","wikidata":"https://www.wikidata.org/wiki/Q61641151","display_name":"Cyfluthrin","level":4,"score":0.9416890740394592},{"id":"https://openalex.org/C2776035571","wikidata":"https://www.wikidata.org/wiki/Q745766","display_name":"Pyrethroid","level":3,"score":0.6279133558273315},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.497466117143631},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4449543058872223},{"id":"https://openalex.org/C2779752676","wikidata":"https://www.wikidata.org/wiki/Q411635","display_name":"Permethrin","level":3,"score":0.4426219165325165},{"id":"https://openalex.org/C2779437720","wikidata":"https://www.wikidata.org/wiki/Q412024","display_name":"Cypermethrin","level":3,"score":0.4248407185077667},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.24930962920188904},{"id":"https://openalex.org/C161176658","wikidata":"https://www.wikidata.org/wiki/Q131656","display_name":"Pesticide","level":2,"score":0.06935450434684753},{"id":"https://openalex.org/C6557445","wikidata":"https://www.wikidata.org/wiki/Q173113","display_name":"Agronomy","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000726","descriptor_name":"Androgen Antagonists","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005837","descriptor_name":"Genitalia, Male","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005837","descriptor_name":"Genitalia, Male","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009929","descriptor_name":"Organ Size","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D010575","descriptor_name":"Pesticides","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D011722","descriptor_name":"Pyrethrins","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D011944","descriptor_name":"Receptors, Androgen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.reprotox.2008.05.054","doi":"https://doi.org/10.1016/j.reprotox.2008.05.054","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.reprotox.2008.05.054","pdf_url":null,"source":{"id":"https://openalex.org/S1879512","display_name":"Reproductive Toxicology","issn_l":"0890-6238","issn":["0890-6238","1873-1708"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproductive Toxicology","raw_type":"journal-article"},{"id":"pmid:18586453","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18586453","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproductive toxicology (Elmsford, N.Y.)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.504800021648407,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320241","display_name":"Academy of Medical Sciences","ror":"https://ror.org/00c489v88"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320332162","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12"},{"id":"https://openalex.org/F4320338464","display_name":"Natural Science Foundation of Zhejiang Province","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W1596785551","https://openalex.org/W1963847535","https://openalex.org/W1973845558","https://openalex.org/W1986283698","https://openalex.org/W1986401122","https://openalex.org/W1995028694","https://openalex.org/W2006112787","https://openalex.org/W2007908190","https://openalex.org/W2009040345","https://openalex.org/W2018012617","https://openalex.org/W2018666042","https://openalex.org/W2025048879","https://openalex.org/W2030742472","https://openalex.org/W2032757820","https://openalex.org/W2039427523","https://openalex.org/W2050044266","https://openalex.org/W2051552470","https://openalex.org/W2061694266","https://openalex.org/W2066321889","https://openalex.org/W2068765072","https://openalex.org/W2071685183","https://openalex.org/W2073453642","https://openalex.org/W2079695956","https://openalex.org/W2097913296","https://openalex.org/W2098707152","https://openalex.org/W2108241608","https://openalex.org/W2120798598","https://openalex.org/W2130430758","https://openalex.org/W2138067748","https://openalex.org/W2158086932","https://openalex.org/W2158537274","https://openalex.org/W2326357482","https://openalex.org/W2351797328","https://openalex.org/W2414772179","https://openalex.org/W3150795951"],"related_works":["https://openalex.org/W2070633183","https://openalex.org/W2098707152","https://openalex.org/W2018666042","https://openalex.org/W3177188158","https://openalex.org/W2006112787","https://openalex.org/W2351797328","https://openalex.org/W2274088966","https://openalex.org/W2051552470","https://openalex.org/W1994588237","https://openalex.org/W2132929798"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}