{"id":"https://openalex.org/W2092409671","doi":"https://doi.org/10.1159/000123517","title":"Comparative Immunocytochemical Localization of Corticotropin Releasing Factor (CRF-41) and Neurohypophysial Peptides in the Brain of Brattleboro and Long-Evans Rats","display_name":"Comparative Immunocytochemical Localization of Corticotropin Releasing Factor (CRF-41) and Neurohypophysial Peptides in the Brain of Brattleboro and Long-Evans Rats","publication_year":2008,"publication_date":"2008-03-27","ids":{"openalex":"https://openalex.org/W2092409671","doi":"https://doi.org/10.1159/000123517","mag":"2092409671","pmid":"https://pubmed.ncbi.nlm.nih.gov/6604239"},"language":"en","primary_location":{"id":"doi:10.1159/000123517","doi":"https://doi.org/10.1159/000123517","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000123517","pdf_url":null,"source":{"id":"https://openalex.org/S84102376","display_name":"Neuroendocrinology","issn_l":"0028-3835","issn":["0028-3835","1423-0194"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroendocrinology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022929203","display_name":"Arlette J. Burlet","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Arlette Burlet","raw_affiliation_strings":["Facult\u00e9 de M\u00e9decine, Laboratoire d'Histologie A, Vand\u0153uvre-les-Nancy, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Facult\u00e9 de M\u00e9decine, Laboratoire d'Histologie A, Vand\u0153uvre-les-Nancy, France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113986713","display_name":"Marie\u2010Christine Tonon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I62396329","display_name":"Universit\u00e9 de Rouen Normandie","ror":"https://ror.org/03nhjew95","country_code":"FR","type":"education","lineage":["https://openalex.org/I4210105918","https://openalex.org/I62396329"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Marie-Christine Tonon","raw_affiliation_strings":["Groupe de Recherche en Endocrinologie Mol\u00e9culaire, Facult\u00e9 des Sciences de Rouen, Mont-Saint-Aignan, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Groupe de Recherche en Endocrinologie Mol\u00e9culaire, Facult\u00e9 des Sciences de Rouen, Mont-Saint-Aignan, France","institution_ids":["https://openalex.org/I62396329"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026990462","display_name":"Pierre Tankosic","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pierre Tankosic","raw_affiliation_strings":["Facult\u00e9 de M\u00e9decine, Laboratoire d'Histologie A, Vand\u0153uvre-les-Nancy, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Facult\u00e9 de M\u00e9decine, Laboratoire d'Histologie A, Vand\u0153uvre-les-Nancy, France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105303013","display_name":"David H. Coy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Coy","raw_affiliation_strings":["Veterans Administration Medical Center, Tulane University, New Orleans, La., USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Veterans Administration Medical Center, Tulane University, New Orleans, La., USA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5105885862","display_name":"Hubert Vaudry","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I62396329","display_name":"Universit\u00e9 de Rouen Normandie","ror":"https://ror.org/03nhjew95","country_code":"FR","type":"education","lineage":["https://openalex.org/I4210105918","https://openalex.org/I62396329"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Hubert Vaudry","raw_affiliation_strings":["Groupe de Recherche en Endocrinologie Mol\u00e9culaire, Facult\u00e9 des Sciences de Rouen, Mont-Saint-Aignan, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Groupe de Recherche en Endocrinologie Mol\u00e9culaire, Facult\u00e9 des Sciences de Rouen, Mont-Saint-Aignan, France","institution_ids":["https://openalex.org/I62396329"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.3334,"has_fulltext":false,"cited_by_count":119,"citation_normalized_percentile":{"value":0.85355628,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"37","issue":"1","first_page":"64","last_page":"72"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11541","display_name":"Neuroendocrine regulation and behavior","score":0.6869999766349792,"subfield":{"id":"https://openalex.org/subfields/3207","display_name":"Social Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T11541","display_name":"Neuroendocrine regulation and behavior","score":0.6869999766349792,"subfield":{"id":"https://openalex.org/subfields/3207","display_name":"Social Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.26030001044273376,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.019500000402331352,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/corticotropin-releasing-factor","display_name":"corticotropin-releasing factor","score":0.9599999785423279},{"id":"https://openalex.org/keywords/vasopressin","display_name":"vasopressin","score":0.8159999847412109},{"id":"https://openalex.org/keywords/oxytocin","display_name":"oxytocin","score":1.0},{"id":"https://openalex.org/keywords/neurophysin-i","display_name":"neurophysin I","score":0.8330000042915344},{"id":"https://openalex.org/keywords/anterior-hypothalamus","display_name":"anterior hypothalamus","score":0.8040000200271606},{"id":"https://openalex.org/keywords/supraoptic-nucleus","display_name":"supraoptic nucleus","score":0.8899999856948853},{"id":"https://openalex.org/keywords/diabetes-insipidus","display_name":"diabetes insipidus","score":0.800000011920929},{"id":"https://openalex.org/keywords/brattleboro-rats","display_name":"Brattleboro rats","score":0.9190000295639038},{"id":"https://openalex.org/keywords/long-evans-rats","display_name":"Long-Evans rats","score":0.9620000123977661},{"id":"https://openalex.org/keywords/colchicine","display_name":"colchicine","score":0.8119999766349792},{"id":"https://openalex.org/keywords/desmopressin","display_name":"desmopressin","score":0.8059999942779541},{"id":"https://openalex.org/keywords/neurohypophysis","display_name":"neurohypophysis","score":0.7239999771118164},{"id":"https://openalex.org/keywords/neuroendocrine-regulation","display_name":"neuroendocrine regulation","score":0.4090000092983246}],"concepts":[{"id":"https://openalex.org/C6162580","wikidata":"https://www.wikidata.org/wiki/Q5649486","display_name":"Neurophysins","level":3,"score":0.8173530101776123},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.8153188228607178},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8029136061668396},{"id":"https://openalex.org/C2776370428","wikidata":"https://www.wikidata.org/wiki/Q21124841","display_name":"Vasopressin","level":2,"score":0.7782807350158691},{"id":"https://openalex.org/C2776958162","wikidata":"https://www.wikidata.org/wiki/Q220551","display_name":"Diabetes insipidus","level":2,"score":0.7246250510215759},{"id":"https://openalex.org/C2777003273","wikidata":"https://www.wikidata.org/wiki/Q164386","display_name":"Hypothalamus","level":2,"score":0.7235939502716064},{"id":"https://openalex.org/C2776176026","wikidata":"https://www.wikidata.org/wiki/Q169960","display_name":"Oxytocin","level":2,"score":0.7180903553962708},{"id":"https://openalex.org/C2780297037","wikidata":"https://www.wikidata.org/wiki/Q1503735","display_name":"Posterior pituitary","level":4,"score":0.698572039604187},{"id":"https://openalex.org/C2776636253","wikidata":"https://www.wikidata.org/wiki/Q326224","display_name":"Colchicine","level":2,"score":0.5793092846870422},{"id":"https://openalex.org/C118303440","wikidata":"https://www.wikidata.org/wiki/Q419968","display_name":"Neuropeptide","level":3,"score":0.5217652916908264},{"id":"https://openalex.org/C2779029589","wikidata":"https://www.wikidata.org/wiki/Q356002","display_name":"Anterior pituitary","level":3,"score":0.4849238693714142},{"id":"https://openalex.org/C2777687476","wikidata":"https://www.wikidata.org/wiki/Q492272","display_name":"Supraoptic nucleus","level":3,"score":0.47414323687553406},{"id":"https://openalex.org/C2778458438","wikidata":"https://www.wikidata.org/wiki/Q386664","display_name":"Corticotropin-releasing hormone","level":3,"score":0.46919652819633484},{"id":"https://openalex.org/C2777688879","wikidata":"https://www.wikidata.org/wiki/Q904550","display_name":"Urocortin","level":3,"score":0.4491738975048065},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.42322126030921936},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3377167582511902},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.33534467220306396},{"id":"https://openalex.org/C2777658017","wikidata":"https://www.wikidata.org/wiki/Q156871","display_name":"Pituitary gland","level":3,"score":0.31489038467407227},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3021714687347412},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.17290830612182617},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.15653783082962036}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001127","descriptor_name":"Arginine Vasopressin","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D001923","descriptor_name":"Brain Chemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003346","descriptor_name":"Corticotropin-Releasing Hormone","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D003919","descriptor_name":"Diabetes Insipidus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D004326","descriptor_name":"Drinking","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009481","descriptor_name":"Neurophysins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D010121","descriptor_name":"Oxytocin","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D010904","descriptor_name":"Pituitary Gland, Posterior","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D011863","descriptor_name":"Radioimmunoassay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011910","descriptor_name":"Rats, Brattleboro","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014556","descriptor_name":"Urine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1159/000123517","doi":"https://doi.org/10.1159/000123517","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000123517","pdf_url":null,"source":{"id":"https://openalex.org/S84102376","display_name":"Neuroendocrinology","issn_l":"0028-3835","issn":["0028-3835","1423-0194"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroendocrinology","raw_type":"journal-article"},{"id":"pmid:6604239","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6604239","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroendocrinology","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.7699999809265137,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320893","display_name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale","ror":"https://ror.org/02vjkv261"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1972561046","https://openalex.org/W98941923","https://openalex.org/W7095305608","https://openalex.org/W2073918749","https://openalex.org/W1509046486","https://openalex.org/W2062887087","https://openalex.org/W2047048406","https://openalex.org/W2036118884","https://openalex.org/W2092778189","https://openalex.org/W2005405569"],"abstract_inverted_index":{"The":[0],"localization":[1],"of":[2,14,27,40,90,98,106,112],"CRF-41":[3,52,79],"related":[4],"peptide":[5],"was":[6,35,53,61,74],"studied":[7],"in":[8,55,86,94,108,121,128],"the":[9,15,19,28,38,72,87,91,95,99,109],"brain":[10],"and":[11,26,45,69,124],"posterior":[12],"pituitary":[13],"homozygous":[16],"rats":[17,30,123],"for":[18,104],"inherited":[20],"diabetes":[21],"insipidus":[22],"(Brattleboro":[23],"strain,":[24],"DI)":[25],"Long-Evans":[29],"(LE)":[31],"as":[32],"control.":[33],"It":[34],"compared":[36],"to":[37],"distribution":[39],"vasopressin":[41],"(AVP),":[42],"oxytocin":[43],"(OXY)":[44],"OXY-neurophysin":[46],"(N":[47],"I).":[48],"In":[49],"both":[50],"strains,":[51],"identified":[54],"two":[56],"morphologically":[57],"distinct":[58],"systems:":[59],"one":[60],"a":[62,75],"hypothalamoneurohypophysial":[63],"system":[64,77],"simultaneously":[65],"containing":[66,82],"CRF-41,":[67],"OXY":[68],"N":[70],"I;":[71],"other":[73],"hypothalamoinfundibular":[76],"carrying":[78],"only.":[80],"CRF":[81,114],"neurons":[83],"were":[84,116],"located":[85],"periventricular":[88],"area":[89],"anterior":[92],"hypothalamus,":[93],"retrochiasmatic":[96],"part":[97,111],"supraoptic":[100],"nuclei":[101],"(SON)":[102],"and,":[103],"some":[105],"them,":[107],"antechiasmatic":[110],"SON.":[113],"immunostainings":[115],"enhanced":[117],"by":[118,125],"colchicine":[119],"treatment":[120],"LE":[122],"DDAVP":[126],"therapy":[127],"DI":[129],"rats.":[130]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2015,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}