{"id":"https://openalex.org/W2092394611","doi":"https://doi.org/10.1242/jeb.049213","title":"Patterns of tropomyosin and troponin-T isoform expression in jaw-closing muscles of mammals and reptiles that express masticatory myosin","display_name":"Patterns of tropomyosin and troponin-T isoform expression in jaw-closing muscles of mammals and reptiles that express masticatory myosin","publication_year":2011,"publication_date":"2011-03-09","ids":{"openalex":"https://openalex.org/W2092394611","doi":"https://doi.org/10.1242/jeb.049213","mag":"2092394611","pmid":"https://pubmed.ncbi.nlm.nih.gov/21389191"},"language":"en","primary_location":{"id":"doi:10.1242/jeb.049213","doi":"https://doi.org/10.1242/jeb.049213","is_oa":false,"landing_page_url":"https://doi.org/10.1242/jeb.049213","pdf_url":null,"source":{"id":"https://openalex.org/S20257348","display_name":"Journal of Experimental Biology","issn_l":"0022-0949","issn":["0022-0949","1477-9145"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311847","host_organization_name":"The Company of Biologists","host_organization_lineage":["https://openalex.org/P4310311847"],"host_organization_lineage_names":["The Company of Biologists"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Experimental Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113642236","display_name":"Sabahattin Bicer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sabahattin Bicer","raw_affiliation_strings":["Department of Oral Biology, Ecology and Organismal Biology, Ohio State University, Columbus, OH 43210, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral Biology, Ecology and Organismal Biology, Ohio State University, Columbus, OH 43210, USA","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057421052","display_name":"Radhika J. Patel","orcid":"https://orcid.org/0000-0002-6880-0149","observed_orcids":["https://orcid.org/0000-0002-6880-0149"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Radhika J. Patel","raw_affiliation_strings":["Department of Oral Biology, Ecology and Organismal Biology, Ohio State University, Columbus, OH 43210, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral Biology, Ecology and Organismal Biology, Ohio State University, Columbus, OH 43210, USA","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035810794","display_name":"Joseph B. Williams","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph B. Williams","raw_affiliation_strings":["Department of Evolution, Ecology and Organismal Biology, Ohio State University, Columbus, OH 43210, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Evolution, Ecology and Organismal Biology, Ohio State University, Columbus, OH 43210, USA","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075518537","display_name":"Peter J. Reiser","orcid":"https://orcid.org/0000-0003-3677-4211","observed_orcids":["https://orcid.org/0000-0003-3677-4211"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Peter J. Reiser","raw_affiliation_strings":["Department of Oral Biology, Ecology and Organismal Biology, Ohio State University, Columbus, OH 43210, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral Biology, Ecology and Organismal Biology, Ohio State University, Columbus, OH 43210, USA","institution_ids":["https://openalex.org/I52357470"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5075518537","https://openalex.org/A5113642236"],"corresponding_institution_ids":["https://openalex.org/I52357470"],"apc_list":null,"apc_paid":null,"fwci":0.3891,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.60440644,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"214","issue":"7","first_page":"1077","last_page":"1085"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.6133000254631042,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.6133000254631042,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.36719998717308044,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13100","display_name":"Comparative Animal Anatomy Studies","score":0.010300000198185444,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tropomyosin-isoforms","display_name":"tropomyosin isoforms","score":0.9210000038146973},{"id":"https://openalex.org/keywords/troponin-t-isoforms","display_name":"troponin T isoforms","score":0.9139999747276306},{"id":"https://openalex.org/keywords/jaw-closing-muscles","display_name":"jaw-closing muscles","score":0.9309999942779541},{"id":"https://openalex.org/keywords/thin-filament-proteins","display_name":"thin filament proteins","score":0.6710000038146973},{"id":"https://openalex.org/keywords/carnivora","display_name":"Carnivora","score":0.7329999804496765},{"id":"https://openalex.org/keywords/rodents","display_name":"rodents","score":0.984000027179718},{"id":"https://openalex.org/keywords/marsupials","display_name":"marsupials","score":0.968999981880188},{"id":"https://openalex.org/keywords/reptiles","display_name":"reptiles","score":0.7689999938011169},{"id":"https://openalex.org/keywords/feeding-style","display_name":"feeding style","score":0.6010000109672546},{"id":"https://openalex.org/keywords/muscle-fiber-type","display_name":"muscle fiber type","score":0.5889999866485596},{"id":"https://openalex.org/keywords/phylogenetic-comparison","display_name":"phylogenetic comparison","score":0.5870000123977661}],"concepts":[{"id":"https://openalex.org/C193206974","wikidata":"https://www.wikidata.org/wiki/Q6785539","display_name":"Masticatory force","level":2,"score":0.7690688967704773},{"id":"https://openalex.org/C53345823","wikidata":"https://www.wikidata.org/wiki/Q5531554","display_name":"Gene isoform","level":3,"score":0.756787896156311},{"id":"https://openalex.org/C205875245","wikidata":"https://www.wikidata.org/wiki/Q418454","display_name":"Tropomyosin","level":3,"score":0.7491228580474854},{"id":"https://openalex.org/C6997183","wikidata":"https://www.wikidata.org/wiki/Q271727","display_name":"Myosin","level":2,"score":0.7209393978118896},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7165294289588928},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.5546888113021851},{"id":"https://openalex.org/C2778961482","wikidata":"https://www.wikidata.org/wiki/Q25241","display_name":"Vertebrate","level":3,"score":0.48701268434524536},{"id":"https://openalex.org/C2780451601","wikidata":"https://www.wikidata.org/wiki/Q25306","display_name":"Carnivora","level":2,"score":0.4757014214992523},{"id":"https://openalex.org/C2778950215","wikidata":"https://www.wikidata.org/wiki/Q177601","display_name":"Macaque","level":2,"score":0.42825746536254883},{"id":"https://openalex.org/C90856448","wikidata":"https://www.wikidata.org/wiki/Q431","display_name":"Zoology","level":1,"score":0.40870121121406555},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.39944693446159363},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.2570928931236267},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.18276801705360413},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.1503860056400299},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.13830164074897766},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09217128157615662},{"id":"https://openalex.org/C46312422","wikidata":"https://www.wikidata.org/wiki/Q11024","display_name":"Communication","level":1,"score":0.08362191915512085},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004591","descriptor_name":"Electrophoresis, Polyacrylamide Gel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005075","descriptor_name":"Biological Evolution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005247","descriptor_name":"Feeding Behavior","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007568","descriptor_name":"Jaw","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008322","descriptor_name":"Mammals","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008410","descriptor_name":"Masticatory Muscles","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009218","descriptor_name":"Myosins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012104","descriptor_name":"Reptiles","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014335","descriptor_name":"Tropomyosin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015151","descriptor_name":"Immunoblotting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020107","descriptor_name":"Troponin T","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1242/jeb.049213","doi":"https://doi.org/10.1242/jeb.049213","is_oa":false,"landing_page_url":"https://doi.org/10.1242/jeb.049213","pdf_url":null,"source":{"id":"https://openalex.org/S20257348","display_name":"Journal of Experimental Biology","issn_l":"0022-0949","issn":["0022-0949","1477-9145"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311847","host_organization_name":"The Company of Biologists","host_organization_lineage":["https://openalex.org/P4310311847"],"host_organization_lineage_names":["The Company of Biologists"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Experimental Biology","raw_type":"journal-article"},{"id":"pmid:21389191","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21389191","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of experimental biology","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":67,"referenced_works":["https://openalex.org/W46742610","https://openalex.org/W62960180","https://openalex.org/W91200975","https://openalex.org/W100181733","https://openalex.org/W1503786179","https://openalex.org/W1514549854","https://openalex.org/W1515638484","https://openalex.org/W1523872131","https://openalex.org/W1560559119","https://openalex.org/W1592971923","https://openalex.org/W1890150156","https://openalex.org/W1964600827","https://openalex.org/W1967209412","https://openalex.org/W1972396190","https://openalex.org/W1975446628","https://openalex.org/W1975538320","https://openalex.org/W1978032840","https://openalex.org/W1978398270","https://openalex.org/W1978972120","https://openalex.org/W1981234963","https://openalex.org/W1983155673","https://openalex.org/W1985710170","https://openalex.org/W1987323614","https://openalex.org/W1993621350","https://openalex.org/W1998819333","https://openalex.org/W2015403539","https://openalex.org/W2015550057","https://openalex.org/W2020138719","https://openalex.org/W2021818489","https://openalex.org/W2023451412","https://openalex.org/W2026389814","https://openalex.org/W2027370226","https://openalex.org/W2029908959","https://openalex.org/W2032405270","https://openalex.org/W2039544289","https://openalex.org/W2042048838","https://openalex.org/W2043640284","https://openalex.org/W2043860686","https://openalex.org/W2048682334","https://openalex.org/W2051553136","https://openalex.org/W2059892055","https://openalex.org/W2060957200","https://openalex.org/W2061026314","https://openalex.org/W2064641129","https://openalex.org/W2066272939","https://openalex.org/W2070890509","https://openalex.org/W2075739506","https://openalex.org/W2078865229","https://openalex.org/W2081147724","https://openalex.org/W2081561538","https://openalex.org/W2094038629","https://openalex.org/W2095648190","https://openalex.org/W2098548847","https://openalex.org/W2108792178","https://openalex.org/W2117463248","https://openalex.org/W2120756380","https://openalex.org/W2121459900","https://openalex.org/W2124138766","https://openalex.org/W2136541849","https://openalex.org/W2137110772","https://openalex.org/W2144445280","https://openalex.org/W2149220457","https://openalex.org/W2164590764","https://openalex.org/W2169868647","https://openalex.org/W2176715668","https://openalex.org/W2183214884","https://openalex.org/W2263307112"],"related_works":["https://openalex.org/W2093558781","https://openalex.org/W2121459900","https://openalex.org/W2108792178","https://openalex.org/W2247603041","https://openalex.org/W1978398270","https://openalex.org/W2023451412","https://openalex.org/W2046629954","https://openalex.org/W2026073293","https://openalex.org/W2150983431","https://openalex.org/W2020138719"],"abstract_inverted_index":{"We":[0,163],"recently":[1],"reported":[2],"that":[3,78,165,199],"masticatory":[4,80,183],"('superfast')":[5],"myosin":[6],"is":[7],"expressed":[8],"in":[9,35,68,142,148,168,189,205,216],"jaw-closing":[10,32,70,112,149],"muscles":[11,71,115,150],"of":[12,37,43,54,61,72,90,93,111,116,119,123,127,137,182,211],"some":[13,206],"rodent":[14],"species.":[15],"Most":[16],"mammalian":[17],"limb":[18,114],"muscle":[19,33,191],"fibers":[20,34],"express":[21,39,79],"tropomyosin-\u03b2":[22,29],"(Tm-\u03b2),":[23,30],"along":[24],"with":[25],"fast-type":[26,107],"or":[27,49],"slow-type":[28],"but":[31,154],"members":[36,89,210],"Carnivora":[38],"a":[40],"unique":[41],"isoform":[42,66,109,146,172],"Tm":[44,62,105,143,169],"[Tm-masticatory":[45],"(Tm-M)]":[46],"and":[47,63,74,82,97,106,113,134,144,170,213],"little":[48],"no":[50],"Tm-\u03b2.":[51],"The":[52],"goal":[53],"this":[55],"study":[56],"was":[57],"to":[58,86,102,193],"determine":[59],"patterns":[60,159,174],"troponin-T":[64],"(TnT)":[65],"expression":[67,147,173,181],"the":[69,84,104,166,180],"rodents":[73],"other":[75],"vertebrate":[76],"species":[77,118,122,126,136,207],"myosin,":[81,184],"compare":[83],"results":[85],"those":[87],"from":[88],"Carnivora.":[91],"Comparisons":[92],"electrophoretic":[94],"mobility,":[95],"immunoblotting":[96],"mass":[98],"spectrometry":[99],"were":[100],"used":[101],"probe":[103],"TnT":[108,145,171],"composition":[110],"six":[117,135],"Carnivora,":[120],"eight":[121],"Rodentia,":[124],"five":[125],"Marsupialia,":[128],"big":[129],"brown":[130],"bat,":[131],"long-tailed":[132],"macaque":[133],"Reptilia.":[138],"Extensive":[139],"heterogeneity":[140],"exists":[141],"between":[151,175],"phylogenetic":[152,176],"groups,":[153,177],"there":[155],"are":[156],"fairly":[157],"consistent":[158],"within":[160],"each":[161],"group.":[162],"propose":[164],"differences":[167,188],"which":[178],"share":[179],"may":[185,200],"impart":[186],"fundamental":[187],"thin-filament-mediated":[190],"activation":[192],"accommodate":[194],"markedly":[195],"different":[196],"feeding":[197],"styles":[198],"require":[201],"high":[202,214],"force":[203],"generation":[204],"(e.g.":[208,218],"many":[209],"Carnivora)":[212],"speed":[215],"others":[217],"Rodentia).":[219]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}