{"id":"https://openalex.org/W2092385337","doi":"https://doi.org/10.1055/s-2007-988529","title":"Zur Versorgungssituation von Patienten mit chronischer Hepatitis C (cHC) und Leberzirrhose in Deutschland, ein aktueller Statusbericht","display_name":"Zur Versorgungssituation von Patienten mit chronischer Hepatitis C (cHC) und Leberzirrhose in Deutschland, ein aktueller Statusbericht","publication_year":2007,"publication_date":"2007-08-01","ids":{"openalex":"https://openalex.org/W2092385337","doi":"https://doi.org/10.1055/s-2007-988529","mag":"2092385337"},"language":"de","primary_location":{"id":"doi:10.1055/s-2007-988529","doi":"https://doi.org/10.1055/s-2007-988529","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-2007-988529","pdf_url":null,"source":{"id":"https://openalex.org/S189922908","display_name":"Zeitschrift f\u00fcr Gastroenterologie","issn_l":"0044-2771","issn":["0044-2771","1439-7803"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zeitschrift f\u00fcr Gastroenterologie","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038778812","display_name":"D H\u00fcppe","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D H\u00fcppe","raw_affiliation_strings":["Gastroenterologische Praxis, Herne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterologische Praxis, Herne, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070564415","display_name":"S Mauss","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210129859","display_name":"Center for HIV and Hepatogastroenterology","ror":"https://ror.org/03srd4412","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210129859"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"S Mauss","raw_affiliation_strings":["Zentrum f\u00fcr HIV and Hepatogastroenterologie D\u00fcsseldorf, D\u00fcsseldorf, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Zentrum f\u00fcr HIV and Hepatogastroenterologie D\u00fcsseldorf, D\u00fcsseldorf, Germany","institution_ids":["https://openalex.org/I4210129859"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012564454","display_name":"K.H.W. Boeker","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K Boeker","raw_affiliation_strings":["Gastroenterologische Praxis, Hannover, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterologische Praxis, Hannover, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"T Lutz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210116308","display_name":"Infektionsmedizinisches Centrum Hamburg","ror":"https://ror.org/01mp0e364","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210116308"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"T Lutz","raw_affiliation_strings":["Infektiologische Praxis, Frankfurt, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Infektiologische Praxis, Frankfurt, Germany","institution_ids":["https://openalex.org/I4210116308"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051202418","display_name":"Stefan A. Racky","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S Racky","raw_affiliation_strings":["Gastroenterologische Praxis, Bad Schwalbach, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterologische Praxis, Bad Schwalbach, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111040183","display_name":"Wolfgang Ekkehard Schmidt","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W Schmidt","raw_affiliation_strings":["\u00c4rzteforum Seestra\u00dfe, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u00c4rzteforum Seestra\u00dfe, Berlin, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"R Ulrich","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Ulrich","raw_affiliation_strings":["Gastroenterologische Praxis, Krefeld, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterologische Praxis, Krefeld, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079977090","display_name":"I. Sbrijer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"I Sbrijer","raw_affiliation_strings":["Gastroenterologische Praxis, Dortmund, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterologische Praxis, Dortmund, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041124674","display_name":"Renate Heyne","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Heyne","raw_affiliation_strings":["Gastroenterologische Zentrum und Leberambulanz, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterologische Zentrum und Leberambulanz, Berlin, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029356632","display_name":"Andreas Schober","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Schober","raw_affiliation_strings":["Gastroenterologische Praxis, G\u00f6ttingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterologische Praxis, G\u00f6ttingen, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109402459","display_name":"C John","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C John","raw_affiliation_strings":["Gastroenterologische Praxis, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterologische Praxis, Berlin, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065798573","display_name":"KH Hey","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"KH Hey","raw_affiliation_strings":["Gastroenterologische Praxis, Paderborn, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterologische Praxis, Paderborn, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058697669","display_name":"Bernd Bokemeyer","orcid":"https://orcid.org/0000-0003-2016-6991","observed_orcids":["https://orcid.org/0000-0003-2016-6991"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B Bokemeyer","raw_affiliation_strings":["Gastroenterologische Praxis, Minden, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterologische Praxis, Minden, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048475759","display_name":"B. Kallinowski","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B Kallinowski","raw_affiliation_strings":["Gastroenterologische Schwerpunktpraxis, Schwetzingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterologische Schwerpunktpraxis, Schwetzingen, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081677181","display_name":"Burkhard M\u00f6ller","orcid":"https://orcid.org/0000-0001-8769-6167","observed_orcids":["https://orcid.org/0000-0001-8769-6167"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B M\u00f6ller","raw_affiliation_strings":["Gastroenterologische Zentrum und Leberambulanz, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterologische Zentrum und Leberambulanz, Berlin, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020202167","display_name":"Stefan Pape","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S Pape","raw_affiliation_strings":["Gastroenterologische Praxis, Paderborn, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterologische Praxis, Paderborn, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088473419","display_name":"U. Alsh\u00fcth","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094361","display_name":"Roche Pharma AG (Germany)","ror":"https://ror.org/00sh68184","country_code":"DE","type":"company","lineage":["https://openalex.org/I118019719","https://openalex.org/I4210094361"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"U Alshuth","raw_affiliation_strings":["Roche Pharma AG, Hepatitis/HIV/Infektiologie, Grenzach-Wyhlen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Roche Pharma AG, Hepatitis/HIV/Infektiologie, Grenzach-Wyhlen, Germany","institution_ids":["https://openalex.org/I4210094361"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033641882","display_name":"E Zehnter","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E Zehnter","raw_affiliation_strings":["Gastroenterologische Praxis, Dortmund, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterologische Praxis, Dortmund, Germany","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.20411369,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"45","issue":"08","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10151","display_name":"Hepatitis C virus research","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10151","display_name":"Hepatitis C virus research","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.00279999990016222,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-hepatitis-c","display_name":"chronic hepatitis C","score":0.996999979019165},{"id":"https://openalex.org/keywords/liver-cirrhosis","display_name":"liver cirrhosis","score":0.9950000047683716},{"id":"https://openalex.org/keywords/health-care-utilization","display_name":"health care utilization","score":0.527999997138977},{"id":"https://openalex.org/keywords/screening","display_name":"screening","score":0.30399999022483826},{"id":"https://openalex.org/keywords/child-pugh-score","display_name":"Child-Pugh score","score":0.625},{"id":"https://openalex.org/keywords/hcv-genotypes","display_name":"HCV genotypes","score":0.578000009059906},{"id":"https://openalex.org/keywords/peginterferon-alfa-2a","display_name":"peginterferon alfa-2a","score":0.8830000162124634},{"id":"https://openalex.org/keywords/ribavirin","display_name":"ribavirin","score":0.9950000047683716},{"id":"https://openalex.org/keywords/hcv-viral-load","display_name":"HCV RNA viral load","score":0.5260000228881836}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8732589483261108},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.489388644695282}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1055/s-2007-988529","doi":"https://doi.org/10.1055/s-2007-988529","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-2007-988529","pdf_url":null,"source":{"id":"https://openalex.org/S189922908","display_name":"Zeitschrift f\u00fcr Gastroenterologie","issn_l":"0044-2771","issn":["0044-2771","1439-7803"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zeitschrift f\u00fcr Gastroenterologie","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2743094531","https://openalex.org/W2749721091","https://openalex.org/W1996000765","https://openalex.org/W2313667045","https://openalex.org/W2314563101","https://openalex.org/W2028651027","https://openalex.org/W2626304925","https://openalex.org/W2331020288","https://openalex.org/W4396749571","https://openalex.org/W4416643800"],"abstract_inverted_index":{"Einleitung:":[0],"Zur":[1],"Beurteilung":[2],"der":[3,9,157,184,214,233,260],"Versorgungsqualit\u00e4t":[4],"von":[5,47,259,270],"cHC":[6],"Patienten":[7,27,61,122,185,215,226,247,282],"f\u00fchrt":[8],"Bundesverband":[10],"niedergelassener":[11],"Gastroenterologen":[12],"(bng)":[13],"in":[14,219],"Kooperation":[15],"mit":[16,28,167,186,283],"Roche":[17],"eine":[18,32,94,223],"deutschlandweite":[19],"online-AWB":[20],"bestehend":[21],"aus":[22],"Screening-":[23],"und":[24,63,108,229,235],"Therapiedokumentation":[25],"durch.":[26],"cHC,":[29],"die":[30,45,58,103,237,269],"bereits":[31,222],"Leberzirrhose":[33],"entwickelt":[34],"haben,":[35],"sind":[36,227],"besonders":[37],"behandlungsbed\u00fcrftig,":[38],"da":[39],"sie":[40],"ein":[41],"erh\u00f6htes":[42],"Risiko":[43],"f\u00fcr":[44,193],"Entwicklung":[46],"leberassoziierten":[48],"Erkrankungen":[49,278],"bzw.":[50,87,276],"eines":[51],"HCC":[52],"haben.":[53],"Ziel:":[54],"Die":[55,119,165,182,225],"Analyse":[56],"soll":[57],"Versorgungssituation":[59],"obiger":[60],"beschreiben":[62],"aufzeigen,":[64],"ob":[65],"Optimierungsm\u00f6glichkeiten":[66],"bestehen.":[67],"Ergebnis:":[68],"Von":[69],"M\u00e4rz":[70],"2003":[71],"bis":[72],"Mai":[73],"2006":[74],"wurden":[75],"10326":[76],"Screeninguntersuchungen":[77],"dokumentiert,":[78],"davon":[79],"hatten":[80,152],"459/8464":[81],"(5,4%)":[82],"nach":[83,90,109,174],"sonograph.":[84,120],"Befund":[85,92],"(S)":[86,188],"81/2234":[88],"(3,6%)":[89],"histologischem":[91],"(H)":[93],"Zirrhose":[95,104,187],"(F4,":[96],"Desmet":[97],"Scheuer).":[98],"Bei":[99],"310":[100],"(3,0%)":[101],"wurde":[102],"klinisch":[105],"(K)":[106],"befundet":[107],"Child":[110],"Pugh":[111],"klassifiziert:":[112],"A":[113],"86,5%,":[114],"B":[115],"10,0%,":[116],"C":[117],"3,5%.":[118],"gesicherten":[121],"waren":[123,195],"58,2J.":[124],"alt,":[125],"60,6%":[126],"M\u00e4nner,":[127],"BMI":[128],"26,3kg/m":[129],"2":[130],",":[131],"Thrombozyten":[132],"137989/\u00b5l,":[133],"mittlere":[134],"Infektionsdauer:":[135],"19,2J.,":[136],"Infektionsquelle":[137],"(>1":[138],"Antwort":[139],"m\u00f6glich):":[140],"Blutprodukte":[141],"31,4%,":[142],"iv":[143],"Drogenabusus":[144],"23,7%,":[145],"Med.":[146],"Ma\u00dfnahme":[147],"8,7%,":[148],"unbekannt":[149],"35,3%.":[150],"12,2%":[151],"aktuell":[153],"einen":[154],"Alkoholabusus.":[155],"Verteilung":[156],"Genotypen:":[158],"G-1":[159],"75,3%,":[160],"G-2/3":[161],"21,1%,":[162],"G-4":[163],"3,1%.":[164],"Behandlungsquote":[166],"Peginterferon":[168],"alfa-2a":[169],"&":[170],"Ribavirin":[171],"betrug":[172,189],"je":[173],"Befundung":[175],"31,4%":[176],"(S),":[177],"75,3%":[178],"(H),":[179],"42,6%":[180],"(K).":[181],"SVR-Rate":[183],"37,3%":[190],"(28/75).":[191],"Gr\u00fcnde":[192],"Nichttherapie":[194],"(Gruppe":[196],"S):":[197],"dekompensierte":[198],"Erkrankung":[199],"33,6%,":[200],"andere":[201],"Therapie":[202],"10,2%,":[203],"Begleiterkrankung/fortges.":[204],"Drogenkonsum":[205],"25,7%,":[206],"Patientenwunsch":[207],"22,2%,":[208],"Alter":[209],"8,3%.":[210],"Schlussfolgerung:":[211],"Etwa":[212],"3\u20135%":[213],"zeigen":[216],"bei":[217,245,253],"Vorstellung":[218],"einem":[220],"Behandlungszentrum":[221],"Zirrhose.":[224],"\u00e4lter":[228],"l\u00e4nger":[230],"infiziert":[231],"als":[232,255],"Durchschnitt":[234],"haben":[236],"Infektion":[238],"zumeist":[239],"durch":[240],"medizinische":[241],"Eingriffe":[242],"erworben.":[243],"Obgleich":[244],"den":[246,280],"dringender":[248],"Therapiebedarf":[249],"besteht,":[250],"gelingt":[251],"es":[252],"mehr":[254,287],"1/5":[256],"nicht,":[257],"diese":[258],"Indikation":[261],"zu":[262],"\u00fcberzeugen.":[263],"Der":[264],"Therapieerfolg":[265],"erreicht":[266],"unter":[267],"Alltagsbedingungen":[268],"Studien":[271],"bekannte":[272],"Rate.":[273],"Wegen":[274],"Dekompensation":[275],"anderen":[277],"kann":[279],"meisten":[281],"einer":[284],"Interferontherapie":[285],"nicht":[286],"geholfen":[288],"werden.":[289]},"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2016-06-24T00:00:00"}