{"id":"https://openalex.org/W2092250698","doi":"https://doi.org/10.1196/annals.1365.047","title":"Fetal Growth Restriction and Postnatal Development","display_name":"Fetal Growth Restriction and Postnatal Development","publication_year":2006,"publication_date":"2006-12-01","ids":{"openalex":"https://openalex.org/W2092250698","doi":"https://doi.org/10.1196/annals.1365.047","mag":"2092250698","pmid":"https://pubmed.ncbi.nlm.nih.gov/17308157"},"language":"en","primary_location":{"id":"doi:10.1196/annals.1365.047","doi":"https://doi.org/10.1196/annals.1365.047","is_oa":false,"landing_page_url":"https://doi.org/10.1196/annals.1365.047","pdf_url":null,"source":{"id":"https://openalex.org/S8802318","display_name":"Annals of the New York Academy of Sciences","issn_l":"0077-8923","issn":["0077-8923","1749-6632"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the New York Academy of Sciences","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027874206","display_name":"Makarios I. Eleftheriades","orcid":"https://orcid.org/0000-0003-4967-2505","observed_orcids":["https://orcid.org/0000-0003-4967-2505"]},"institutions":[{"id":"https://openalex.org/I124357947","display_name":"University of London","ror":"https://ror.org/04cw6st05","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947"]},{"id":"https://openalex.org/I200777214","display_name":"National and Kapodistrian University of Athens","ror":"https://ror.org/04gnjpq42","country_code":"GR","type":"education","lineage":["https://openalex.org/I200777214"]},{"id":"https://openalex.org/I4210119545","display_name":"Aretaeio Hospital","ror":"https://ror.org/02qvqb543","country_code":"GR","type":"healthcare","lineage":["https://openalex.org/I4210119545"]},{"id":"https://openalex.org/I4210136526","display_name":"Harris Birthright Research Centre for Fetal Medicine","ror":"https://ror.org/03kwycy34","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210136526"]},{"id":"https://openalex.org/I4210153400","display_name":"King's College Hospital","ror":"https://ror.org/044nptt90","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210111135","https://openalex.org/I4210153400"]}],"countries":["GB","GR"],"is_corresponding":true,"raw_author_name":"MAKARIOS ELEFTHERIADES","raw_affiliation_strings":["Harris Birthright Research Centre for Fetal Medicine, King's College Hospital, University of London, London, UK. makarios.eleftheriadis@kcl.ac.uk","Harris Birthright Research Centre for Fetal Medicine, King's College Hospital, University of London, London, United Kingdom","Second Department of Obstetrics and Gynecology, Aretaieio Hospital, University of Athens School of Medicine, Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Harris Birthright Research Centre for Fetal Medicine, King's College Hospital, University of London, London, UK. makarios.eleftheriadis@kcl.ac.uk","institution_ids":["https://openalex.org/I124357947","https://openalex.org/I4210136526","https://openalex.org/I4210153400"]},{"raw_affiliation_string":"Harris Birthright Research Centre for Fetal Medicine, King's College Hospital, University of London, London, United Kingdom","institution_ids":["https://openalex.org/I124357947","https://openalex.org/I4210136526","https://openalex.org/I4210153400"]},{"raw_affiliation_string":"Second Department of Obstetrics and Gynecology, Aretaieio Hospital, University of Athens School of Medicine, Athens, Greece","institution_ids":["https://openalex.org/I200777214","https://openalex.org/I4210119545"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111878425","display_name":"George C. Creatsas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200777214","display_name":"National and Kapodistrian University of Athens","ror":"https://ror.org/04gnjpq42","country_code":"GR","type":"education","lineage":["https://openalex.org/I200777214"]},{"id":"https://openalex.org/I4210119545","display_name":"Aretaeio Hospital","ror":"https://ror.org/02qvqb543","country_code":"GR","type":"healthcare","lineage":["https://openalex.org/I4210119545"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"GEORGE CREATSAS","raw_affiliation_strings":["Second Department of Obstetrics and Gynecology, Aretaieio Hospital, University of Athens School of Medicine, Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Second Department of Obstetrics and Gynecology, Aretaieio Hospital, University of Athens School of Medicine, Athens, Greece","institution_ids":["https://openalex.org/I200777214","https://openalex.org/I4210119545"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080220991","display_name":"Kypros H. Nicolaides","orcid":"https://orcid.org/0000-0003-1266-0711","observed_orcids":["https://orcid.org/0000-0003-1266-0711","https://orcid.org/0000-0003-3515-7684"]},"institutions":[{"id":"https://openalex.org/I124357947","display_name":"University of London","ror":"https://ror.org/04cw6st05","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947"]},{"id":"https://openalex.org/I4210136526","display_name":"Harris Birthright Research Centre for Fetal Medicine","ror":"https://ror.org/03kwycy34","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210136526"]},{"id":"https://openalex.org/I4210153400","display_name":"King's College Hospital","ror":"https://ror.org/044nptt90","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210111135","https://openalex.org/I4210153400"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"KYPROS NICOLAIDES","raw_affiliation_strings":["Harris Birthright Research Centre for Fetal Medicine, King's College Hospital, University of London, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Harris Birthright Research Centre for Fetal Medicine, King's College Hospital, University of London, London, United Kingdom","institution_ids":["https://openalex.org/I124357947","https://openalex.org/I4210136526","https://openalex.org/I4210153400"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5027874206"],"corresponding_institution_ids":["https://openalex.org/I124357947","https://openalex.org/I200777214","https://openalex.org/I4210119545","https://openalex.org/I4210136526","https://openalex.org/I4210153400"],"apc_list":{"value":5080,"currency":"USD","value_usd":5080},"apc_paid":null,"fwci":0.5277,"has_fulltext":false,"cited_by_count":61,"citation_normalized_percentile":{"value":0.46277666,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"1092","issue":"1","first_page":"319","last_page":"330"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11629","display_name":"Birth, Development, and Health","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11629","display_name":"Birth, Development, and Health","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.0142000000923872,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11633","display_name":"Prenatal Substance Exposure Effects","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intrauterine-growth-restriction","display_name":"fetal growth restriction","score":1.0},{"id":"https://openalex.org/keywords/postnatal-development","display_name":"postnatal development","score":0.7599999904632568},{"id":"https://openalex.org/keywords/fetal-programming","display_name":"fetal programming","score":0.6980000138282776},{"id":"https://openalex.org/keywords/hypothalamic-pituitary-adrenal-axis","display_name":"hypothalamic-pituitary-adrenal axis","score":0.9120000004768372},{"id":"https://openalex.org/keywords/neuroendocrine-stress-response","display_name":"neuroendocrine stress response","score":0.7850000262260437},{"id":"https://openalex.org/keywords/uteroplacental-blood-flow","display_name":"uteroplacental blood flow","score":0.9819999933242798},{"id":"https://openalex.org/keywords/fetal-hypoxemia","display_name":"fetal hypoxemia","score":0.8149999976158142},{"id":"https://openalex.org/keywords/perinatal-mortality","display_name":"perinatal mortality","score":0.8920000195503235},{"id":"https://openalex.org/keywords/diabetes-susceptibility","display_name":"diabetes susceptibility","score":0.7620000243186951},{"id":"https://openalex.org/keywords/cardiovascular-disease-susceptibility","display_name":"cardiovascular disease susceptibility","score":0.8140000104904175},{"id":"https://openalex.org/keywords/metabolic-dysfunction","display_name":"metabolic dysfunction","score":0.8989999890327454}],"concepts":[{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6408042311668396},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.584969162940979},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5616414546966553},{"id":"https://openalex.org/C2778780700","wikidata":"https://www.wikidata.org/wiki/Q1671598","display_name":"Intrauterine growth restriction","level":4,"score":0.5323548316955566},{"id":"https://openalex.org/C46699223","wikidata":"https://www.wikidata.org/wiki/Q11078","display_name":"Endocrine system","level":3,"score":0.5318042635917664},{"id":"https://openalex.org/C201614185","wikidata":"https://www.wikidata.org/wiki/Q396833","display_name":"In utero","level":4,"score":0.5115309953689575},{"id":"https://openalex.org/C2993726049","wikidata":"https://www.wikidata.org/wiki/Q2297155","display_name":"Fetal growth","level":4,"score":0.4537116289138794},{"id":"https://openalex.org/C2780352252","wikidata":"https://www.wikidata.org/wiki/Q422543","display_name":"Corticosterone","level":3,"score":0.41981056332588196},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3937000334262848},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.3851451873779297},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.38433724641799927},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.24198654294013977},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09238025546073914}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005317","descriptor_name":"Fetal Growth Retardation","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007030","descriptor_name":"Hypothalamo-Hypophyseal System","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D007030","descriptor_name":"Hypothalamo-Hypophyseal System","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D010913","descriptor_name":"Pituitary-Adrenal System","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D010913","descriptor_name":"Pituitary-Adrenal System","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023421","descriptor_name":"Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1196/annals.1365.047","doi":"https://doi.org/10.1196/annals.1365.047","is_oa":false,"landing_page_url":"https://doi.org/10.1196/annals.1365.047","pdf_url":null,"source":{"id":"https://openalex.org/S8802318","display_name":"Annals of the New York Academy of Sciences","issn_l":"0077-8923","issn":["0077-8923","1749-6632"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the New York Academy of Sciences","raw_type":"journal-article"},{"id":"pmid:17308157","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17308157","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the New York Academy of Sciences","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.979200005531311,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":66,"referenced_works":["https://openalex.org/W183241935","https://openalex.org/W1515251958","https://openalex.org/W1557910385","https://openalex.org/W1633496227","https://openalex.org/W1916395565","https://openalex.org/W1964413701","https://openalex.org/W1966407479","https://openalex.org/W1971440866","https://openalex.org/W1971792043","https://openalex.org/W1972475635","https://openalex.org/W1975468173","https://openalex.org/W1979915761","https://openalex.org/W1980226836","https://openalex.org/W1982307175","https://openalex.org/W1986612174","https://openalex.org/W1993166986","https://openalex.org/W2001688956","https://openalex.org/W2002763203","https://openalex.org/W2010371327","https://openalex.org/W2013094139","https://openalex.org/W2017047206","https://openalex.org/W2022223047","https://openalex.org/W2023676764","https://openalex.org/W2026342628","https://openalex.org/W2028907433","https://openalex.org/W2028944015","https://openalex.org/W2029288555","https://openalex.org/W2035616843","https://openalex.org/W2041005712","https://openalex.org/W2041277193","https://openalex.org/W2043617187","https://openalex.org/W2044669700","https://openalex.org/W2045783445","https://openalex.org/W2046831727","https://openalex.org/W2049079854","https://openalex.org/W2053003164","https://openalex.org/W2054216284","https://openalex.org/W2055001133","https://openalex.org/W2055228751","https://openalex.org/W2056539393","https://openalex.org/W2063109626","https://openalex.org/W2064996282","https://openalex.org/W2068334746","https://openalex.org/W2069619180","https://openalex.org/W2069835471","https://openalex.org/W2070490017","https://openalex.org/W2073974662","https://openalex.org/W2081600521","https://openalex.org/W2086157950","https://openalex.org/W2086376645","https://openalex.org/W2101189704","https://openalex.org/W2110952210","https://openalex.org/W2111793219","https://openalex.org/W2117367121","https://openalex.org/W2126108743","https://openalex.org/W2135550286","https://openalex.org/W2140734898","https://openalex.org/W2151962669","https://openalex.org/W2158973793","https://openalex.org/W2161999371","https://openalex.org/W2171512984","https://openalex.org/W2247136898","https://openalex.org/W2322143790","https://openalex.org/W2339084277","https://openalex.org/W2412622586","https://openalex.org/W4255304519"],"related_works":["https://openalex.org/W841470636","https://openalex.org/W2068273354","https://openalex.org/W2610214361","https://openalex.org/W2934159048","https://openalex.org/W2761515129","https://openalex.org/W7131952277","https://openalex.org/W7096332700","https://openalex.org/W4407084920","https://openalex.org/W1806378060","https://openalex.org/W7167076788"],"abstract_inverted_index":{"The":[0],"interaction":[1],"between":[2],"genetic":[3],"constitution":[4],"and":[5,12,14,27,33,68,73,87,97],"in":[6,21,55,70,88,100,120],"utero":[7],"environment":[8],"determines":[9],"fetal":[10,56],"growth":[11,57,108],"development":[13],"influences":[15],"the":[16,39,89],"susceptibility":[17,94],"to":[18,47,95],"certain":[19],"disorders":[20],"adulthood.":[22,101],"Data":[23],"from":[24],"both":[25],"animal":[26],"human":[28],"studies":[29],"indicate":[30],"that":[31,105],"prenatal":[32],"early":[34,106],"postnatal":[35,107],"malnutrition":[36],"can":[37],"program":[38],"hypothalamus-pituitary-adrenal":[40],"axis":[41],"(HPA":[42],"axis),":[43],"altering":[44],"neuroendocrine":[45],"response":[46],"stressors":[48],"throughout":[49],"lifetime.":[50],"Impaired":[51],"uteroplacental":[52],"perfusion":[53],"results":[54],"restriction":[58],"(FGR).":[59],"In":[60],"FGR":[61,80],"there":[62,91],"is":[63,81,92,103],"evidence":[64,104],"of":[65],"chronic":[66],"hypoxemia":[67],"alterations":[69],"metabolic,":[71],"endocrine,":[72],"hematological":[74],"parameters,":[75],"compatible":[76],"with":[77,83],"starvation.":[78],"Furthermore,":[79],"associated":[82],"increased":[84,93],"perinatal":[85],"mortality":[86],"survivors":[90],"diabetes":[96],"cardiovascular":[98],"disease":[99],"There":[102],"acceleration,":[109],"which":[110],"would":[111],"normally":[112],"be":[113],"considered":[114],"desirable,":[115],"may":[116],"exacerbate":[117],"metabolic":[118],"dysfunction":[119],"later":[121],"life.":[122]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}
