{"id":"https://openalex.org/W2092128564","doi":"https://doi.org/10.1016/0306-4530(90)90029-9","title":"Endogenous opioids modulate the cardiovascular response to mental stress","display_name":"Endogenous opioids modulate the cardiovascular response to mental stress","publication_year":1990,"publication_date":"1990-01-01","ids":{"openalex":"https://openalex.org/W2092128564","doi":"https://doi.org/10.1016/0306-4530(90)90029-9","mag":"2092128564","pmid":"https://pubmed.ncbi.nlm.nih.gov/2255747"},"language":"en","primary_location":{"id":"doi:10.1016/0306-4530(90)90029-9","doi":"https://doi.org/10.1016/0306-4530(90)90029-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0306-4530(90)90029-9","pdf_url":null,"source":{"id":"https://openalex.org/S81924583","display_name":"Psychoneuroendocrinology","issn_l":"0306-4530","issn":["0306-4530","1873-3360"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Psychoneuroendocrinology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"M. Morris","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"M. Morris","raw_affiliation_strings":["Department of Psychology, University College, London"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology, University College, London","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091380756","display_name":"Peter Salmon","orcid":"https://orcid.org/0000-0001-6450-5209","observed_orcids":["https://orcid.org/0000-0001-6450-5209","https://orcid.org/0000-0003-1907-642X"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"P. Salmon","raw_affiliation_strings":["Department of Psychology, University College London, London, England"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology, University College London, London, England","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052338854","display_name":"Hannah Steinberg","orcid":"https://orcid.org/0000-0002-0271-0191","observed_orcids":["https://orcid.org/0000-0002-0271-0191"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"H. Steinberg","raw_affiliation_strings":["Department of Psychology, University College London, London, England"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology, University College London, London, England","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000595262","display_name":"Elizabeth A. Sykes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"E.A. Sykes","raw_affiliation_strings":["Department of Psychology, University College London, London, England"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology, University College London, London, England","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105003642","display_name":"Pierre Marc Bouloux","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1307195382","display_name":"St Bartholomew's Hospital","ror":"https://ror.org/00nh9x179","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307195382","https://openalex.org/I225661044"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"P. Bouloux","raw_affiliation_strings":["Department of Endocrinology, St. Bartholomew's Hospital, London, England","Dept. of Endocrinology, St Bartholomew's Hospital, London, England"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology, St. Bartholomew's Hospital, London, England","institution_ids":["https://openalex.org/I1307195382"]},{"raw_affiliation_string":"Dept. of Endocrinology, St Bartholomew's Hospital, London, England","institution_ids":["https://openalex.org/I1307195382"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085206739","display_name":"Erica Newbould","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1307195382","display_name":"St Bartholomew's Hospital","ror":"https://ror.org/00nh9x179","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307195382","https://openalex.org/I225661044"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"E. Newbould","raw_affiliation_strings":["Department of Endocrinology, St. Bartholomew's Hospital, London, England","Dept. of Endocrinology, St Bartholomew's Hospital, London, England"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology, St. Bartholomew's Hospital, London, England","institution_ids":["https://openalex.org/I1307195382"]},{"raw_affiliation_string":"Dept. of Endocrinology, St Bartholomew's Hospital, London, England","institution_ids":["https://openalex.org/I1307195382"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110144954","display_name":"Lorraine McLoughlin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1307195382","display_name":"St Bartholomew's Hospital","ror":"https://ror.org/00nh9x179","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307195382","https://openalex.org/I225661044"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"L. McLoughlin","raw_affiliation_strings":["Department of Endocrinology, St. Bartholomew's Hospital, London, England","Dept. of Endocrinology, St Bartholomew's Hospital, London, England"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology, St. Bartholomew's Hospital, London, England","institution_ids":["https://openalex.org/I1307195382"]},{"raw_affiliation_string":"Dept. of Endocrinology, St Bartholomew's Hospital, London, England","institution_ids":["https://openalex.org/I1307195382"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111742453","display_name":"G. MICHAEL BESSER","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1307195382","display_name":"St Bartholomew's Hospital","ror":"https://ror.org/00nh9x179","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307195382","https://openalex.org/I225661044"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"G.M. Besser","raw_affiliation_strings":["Department of Endocrinology, St. Bartholomew's Hospital, London, England","Dept. of Endocrinology, St Bartholomew's Hospital, London, England"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology, St. Bartholomew's Hospital, London, England","institution_ids":["https://openalex.org/I1307195382"]},{"raw_affiliation_string":"Dept. of Endocrinology, St Bartholomew's Hospital, London, England","institution_ids":["https://openalex.org/I1307195382"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046852415","display_name":"Ashley Barry Grossman","orcid":"https://orcid.org/0000-0003-1176-6186","observed_orcids":["https://orcid.org/0000-0003-1176-6186"]},"institutions":[{"id":"https://openalex.org/I1307195382","display_name":"St Bartholomew's Hospital","ror":"https://ror.org/00nh9x179","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307195382","https://openalex.org/I225661044"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"A. Grossman","raw_affiliation_strings":["Department of Endocrinology, St. Bartholomew's Hospital, London, England","Dept. of Endocrinology, St Bartholomew's Hospital, London, England"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology, St. Bartholomew's Hospital, London, England","institution_ids":["https://openalex.org/I1307195382"]},{"raw_affiliation_string":"Dept. of Endocrinology, St Bartholomew's Hospital, London, England","institution_ids":["https://openalex.org/I1307195382"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5046852415"],"corresponding_institution_ids":["https://openalex.org/I1307195382"],"apc_list":{"value":3830,"currency":"USD","value_usd":3830},"apc_paid":null,"fwci":1.0561,"has_fulltext":false,"cited_by_count":49,"citation_normalized_percentile":{"value":0.72602198,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"15","issue":"3","first_page":"185","last_page":"192"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.8252000212669373,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.8252000212669373,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.11460000276565552,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.054099999368190765,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/endogenous-opioids","display_name":"endogenous opioids","score":0.9990000128746033},{"id":"https://openalex.org/keywords/psychological-stress","display_name":"psychological stress","score":0.9419999718666077},{"id":"https://openalex.org/keywords/cardiovascular-response","display_name":"cardiovascular response","score":0.9309999942779541},{"id":"https://openalex.org/keywords/naloxone","display_name":"naloxone","score":0.8669999837875366},{"id":"https://openalex.org/keywords/heart-rate","display_name":"heart rate","score":0.9580000042915344},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"blood pressure","score":0.8679999709129333},{"id":"https://openalex.org/keywords/epinephrine","display_name":"epinephrine","score":0.9179999828338623},{"id":"https://openalex.org/keywords/norepinephrine","display_name":"norepinephrine","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cortisol","display_name":"cortisol","score":0.968999981880188},{"id":"https://openalex.org/keywords/acth","display_name":"ACTH","score":0.9990000128746033},{"id":"https://openalex.org/keywords/anxiety","display_name":"anxiety","score":0.8920000195503235}],"concepts":[{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.7324391603469849},{"id":"https://openalex.org/C2778750930","wikidata":"https://www.wikidata.org/wiki/Q4540629","display_name":"(+)-Naloxone","level":4,"score":0.729736864566803},{"id":"https://openalex.org/C3017995582","wikidata":"https://www.wikidata.org/wiki/Q417189","display_name":"Endogenous opioid","level":4,"score":0.7017220258712769},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.5708332657814026},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.5660848021507263},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5458794236183167},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5091208815574646},{"id":"https://openalex.org/C2778514916","wikidata":"https://www.wikidata.org/wiki/Q186242","display_name":"Norepinephrine","level":3,"score":0.4983527660369873},{"id":"https://openalex.org/C2776885963","wikidata":"https://www.wikidata.org/wiki/Q245204","display_name":"Antagonist","level":3,"score":0.4918055832386017},{"id":"https://openalex.org/C2908806481","wikidata":"https://www.wikidata.org/wiki/Q282902","display_name":"Naloxone Hydrochloride","level":5,"score":0.4492553174495697},{"id":"https://openalex.org/C2775859304","wikidata":"https://www.wikidata.org/wiki/Q132621","display_name":"Epinephrine","level":2,"score":0.4451271891593933},{"id":"https://openalex.org/C2775962371","wikidata":"https://www.wikidata.org/wiki/Q908096","display_name":"Opioid antagonist","level":5,"score":0.4328463673591614},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.41721004247665405},{"id":"https://openalex.org/C2781063702","wikidata":"https://www.wikidata.org/wiki/Q427523","display_name":"Opioid","level":3,"score":0.41602978110313416},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4104463458061218},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.16883447766304016},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.08841592073440552},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001007","descriptor_name":"Anxiety","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D004723","descriptor_name":"Endorphins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D004837","descriptor_name":"Epinephrine","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009270","descriptor_name":"Naloxone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D009638","descriptor_name":"Norepinephrine","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D013315","descriptor_name":"Stress, Psychological","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/0306-4530(90)90029-9","doi":"https://doi.org/10.1016/0306-4530(90)90029-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0306-4530(90)90029-9","pdf_url":null,"source":{"id":"https://openalex.org/S81924583","display_name":"Psychoneuroendocrinology","issn_l":"0306-4530","issn":["0306-4530","1873-3360"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Psychoneuroendocrinology","raw_type":"journal-article"},{"id":"pmid:2255747","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2255747","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Psychoneuroendocrinology","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W429936194","https://openalex.org/W1971436310","https://openalex.org/W1993506692","https://openalex.org/W2001828311","https://openalex.org/W2003783857","https://openalex.org/W2039605729","https://openalex.org/W2046364059","https://openalex.org/W2060376092","https://openalex.org/W2062526841","https://openalex.org/W2073680258","https://openalex.org/W2092333372","https://openalex.org/W2107886281","https://openalex.org/W2108059687","https://openalex.org/W2120357670","https://openalex.org/W2167764450","https://openalex.org/W2313220190","https://openalex.org/W2327298537","https://openalex.org/W2418182731","https://openalex.org/W2418333258","https://openalex.org/W2423342107","https://openalex.org/W2809122059","https://openalex.org/W6660252395"],"related_works":["https://openalex.org/W1995308040","https://openalex.org/W2070771711","https://openalex.org/W2323168553","https://openalex.org/W1972530942","https://openalex.org/W2316466220","https://openalex.org/W2086703225","https://openalex.org/W2412512624","https://openalex.org/W2146478526","https://openalex.org/W3175766063","https://openalex.org/W2061372369"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-06-24T00:00:00"}