{"id":"https://openalex.org/W2091991379","doi":"https://doi.org/10.1021/js9503744","title":"NCOMP\u2014A Windows-Based Computer Program for Noncompartmental Analysis of Pharmacokinetic Data","display_name":"NCOMP\u2014A Windows-Based Computer Program for Noncompartmental Analysis of Pharmacokinetic Data","publication_year":1996,"publication_date":"1996-04-01","ids":{"openalex":"https://openalex.org/W2091991379","doi":"https://doi.org/10.1021/js9503744","mag":"2091991379","pmid":"https://pubmed.ncbi.nlm.nih.gov/8901075"},"language":"en","primary_location":{"id":"doi:10.1021/js9503744","doi":"https://doi.org/10.1021/js9503744","is_oa":false,"landing_page_url":"https://doi.org/10.1021/js9503744","pdf_url":null,"source":{"id":"https://openalex.org/S130661733","display_name":"Journal of Pharmaceutical Sciences","issn_l":"0022-3549","issn":["0022-3549","1520-6017"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pharmaceutical Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060289424","display_name":"Paul B. Laub","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1289437631","display_name":"Fox Chase Cancer Center","ror":"https://ror.org/0567t7073","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1289437631","https://openalex.org/I4210122924"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Paul B. Laub","raw_affiliation_strings":["Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA","Department of Medical Oncology Fox Chase Cancer Center 7701 Burholme Avenue Philadelphia, PA 19111"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA","institution_ids":["https://openalex.org/I1289437631"]},{"raw_affiliation_string":"Department of Medical Oncology Fox Chase Cancer Center 7701 Burholme Avenue Philadelphia, PA 19111","institution_ids":["https://openalex.org/I1289437631"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5056500955","display_name":"James M. Gallo","orcid":"https://orcid.org/0000-0003-1553-4817","observed_orcids":["https://orcid.org/0000-0003-1553-4817"]},"institutions":[{"id":"https://openalex.org/I1289437631","display_name":"Fox Chase Cancer Center","ror":"https://ror.org/0567t7073","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1289437631","https://openalex.org/I4210122924"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James M. Gallo","raw_affiliation_strings":["Department of Medical Oncology, Fox Chase Cancer Center, 7701 Burholme Avenue, Philadelphia, PA 19111"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, Fox Chase Cancer Center, 7701 Burholme Avenue, Philadelphia, PA 19111","institution_ids":["https://openalex.org/I1289437631"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5060289424"],"corresponding_institution_ids":["https://openalex.org/I1289437631"],"apc_list":{"value":3620,"currency":"USD","value_usd":3620},"apc_paid":null,"fwci":4.862,"has_fulltext":false,"cited_by_count":57,"citation_normalized_percentile":{"value":0.95405519,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"85","issue":"4","first_page":"393","last_page":"395"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12547","display_name":"Pharmaceutical studies and practices","score":0.3499000072479248,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12547","display_name":"Pharmaceutical studies and practices","score":0.3499000072479248,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11235","display_name":"Statistical Methods in Clinical Trials","score":0.3012999892234802,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.13369999825954437,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/non-compartmental-analysis","display_name":"non-compartmental analysis","score":0.996999979019165},{"id":"https://openalex.org/keywords/area-under-the-curve","display_name":"area under the curve","score":0.8640000224113464},{"id":"https://openalex.org/keywords/lagrange-polynomials","display_name":"Lagrange polynomials","score":0.8960000276565552},{"id":"https://openalex.org/keywords/intravenous-bolus","display_name":"intravenous bolus","score":0.8889999985694885},{"id":"https://openalex.org/keywords/continuous-infusion","display_name":"continuous infusion","score":0.9649999737739563},{"id":"https://openalex.org/keywords/oral-administration","display_name":"oral administration","score":0.8989999890327454},{"id":"https://openalex.org/keywords/windows-software","display_name":"Windows applications","score":0.4970000088214874}],"concepts":[{"id":"https://openalex.org/C2777362769","wikidata":"https://www.wikidata.org/wiki/Q40056","display_name":"Computer program","level":2,"score":0.5453881025314331},{"id":"https://openalex.org/C508378895","wikidata":"https://www.wikidata.org/wiki/Q1406","display_name":"Microsoft Windows","level":3,"score":0.5401604771614075},{"id":"https://openalex.org/C2984927552","wikidata":"https://www.wikidata.org/wiki/Q845734","display_name":"Graphical display","level":2,"score":0.5261228680610657},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.48958906531333923},{"id":"https://openalex.org/C3019730874","wikidata":"https://www.wikidata.org/wiki/Q11272","display_name":"Microsoft excel","level":2,"score":0.4335312843322754},{"id":"https://openalex.org/C43376680","wikidata":"https://www.wikidata.org/wiki/Q6580786","display_name":"Bolus (digestion)","level":2,"score":0.41829586029052734},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.36163046956062317},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.3446728587150574},{"id":"https://openalex.org/C121684516","wikidata":"https://www.wikidata.org/wiki/Q7600677","display_name":"Computer graphics (images)","level":1,"score":0.34114766120910645},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.12021216750144958},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.09377396106719971},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.09000179171562195},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D010599","descriptor_name":"Pharmacokinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1021/js9503744","doi":"https://doi.org/10.1021/js9503744","is_oa":false,"landing_page_url":"https://doi.org/10.1021/js9503744","pdf_url":null,"source":{"id":"https://openalex.org/S130661733","display_name":"Journal of Pharmaceutical Sciences","issn_l":"0022-3549","issn":["0022-3549","1520-6017"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pharmaceutical Sciences","raw_type":"journal-article"},{"id":"pmid:8901075","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8901075","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of pharmaceutical sciences","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.504800021648407}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1208288662","display_name":null,"funder_award_id":"CA09035-20","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G6075332347","display_name":"Training Program in Cancer Research","funder_award_id":"T32CA009035","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000285491","display_name":"Comprehensive Cancer Center Program at Fox Chase","funder_award_id":"P30CA006927","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G921727105","display_name":null,"funder_award_id":"CA06927","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320319101","display_name":"Amsterdam University Medical Centers","ror":"https://ror.org/05grdyy37"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":6,"referenced_works":["https://openalex.org/W33851185","https://openalex.org/W2009136130","https://openalex.org/W2037156603","https://openalex.org/W2042925852","https://openalex.org/W2053289371","https://openalex.org/W2080314044"],"related_works":["https://openalex.org/W2418516410","https://openalex.org/W1968365072","https://openalex.org/W4206958872","https://openalex.org/W2083750945","https://openalex.org/W4414151214","https://openalex.org/W1982085623","https://openalex.org/W2396559747","https://openalex.org/W7162352389","https://openalex.org/W3178405466","https://openalex.org/W2059108971"],"abstract_inverted_index":{"The":[0],"computer":[1],"program":[2,60],"NCOMP":[3,49,68],"performs":[4],"noncompartmental":[5],"analysis":[6],"of":[7,19,22,36,66],"pharmacokinetic":[8],"data":[9],"obtained":[10],"from":[11],"iv":[12,92],"bolus,":[13],"continuous":[14],"infusion,":[15],"and":[16,24,41,64,84],"oral":[17],"modes":[18],"administration.":[20],"Integration":[21],"area-under-the-curve":[23],"area-under-the-first-moment-curve":[25],"is":[26,50],"done":[27],"by":[28],"either":[29],"Lagrange":[30],"polynomials":[31],"or":[32],"the":[33,71,79,87],"hybrid":[34],"method":[35],"Purves,":[37],"which":[38],"uses":[39],"parabola-through-the-origin":[40],"log":[42],"trapezoidal":[43],"algorithms.":[44],"Written":[45],"for":[46,61,91],"Microsoft":[47],"Windows,":[48],"designed":[51],"to":[52,77,81],"be":[53],"used":[54],"in":[55,73,85],"conjunction":[56],"with":[57],"a":[58],"spreadsheet":[59],"graphical":[62],"display":[63],"handling":[65],"data.":[67,94],"interactively":[69],"aids":[70],"user":[72],"determining":[74],"how":[75],"best":[76],"extrapolate":[78],"areas":[80],"time":[82,88],"infinity":[83],"estimating":[86],"zero":[89],"concentration":[90],"bolus":[93]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}