{"id":"https://openalex.org/W2091581601","doi":"https://doi.org/10.1016/s0304-4165(03)00011-4","title":"Structural characterization of En-1, a cold-adapted protein pheromone isolated from the Antarctic ciliate Euplotes nobilii","display_name":"Structural characterization of En-1, a cold-adapted protein pheromone isolated from the Antarctic ciliate Euplotes nobilii","publication_year":2003,"publication_date":"2003-04-01","ids":{"openalex":"https://openalex.org/W2091581601","doi":"https://doi.org/10.1016/s0304-4165(03)00011-4","mag":"2091581601","pmid":"https://pubmed.ncbi.nlm.nih.gov/12667606"},"language":"en","primary_location":{"id":"doi:10.1016/s0304-4165(03)00011-4","doi":"https://doi.org/10.1016/s0304-4165(03)00011-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0304-4165(03)00011-4","pdf_url":null,"source":{"id":"https://openalex.org/S4210238601","display_name":"Biochimica et Biophysica Acta (BBA) - General Subjects","issn_l":"0304-4165","issn":["0304-4165","1872-8006"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - General Subjects","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076875764","display_name":"Claudio Alimenti","orcid":"https://orcid.org/0000-0003-2231-2948","observed_orcids":["https://orcid.org/0000-0003-2231-2948"]},"institutions":[{"id":"https://openalex.org/I112859197","display_name":"Universit\u00e0 di Camerino","ror":"https://ror.org/0005w8d69","country_code":"IT","type":"education","lineage":["https://openalex.org/I112859197"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Claudio Alimenti","raw_affiliation_strings":["Dipartimento di Biologia Molecolare Cellulare e Animale, University of Camerino, Via Camerini 5, 62032 Camerino (MC), Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento di Biologia Molecolare Cellulare e Animale, University of Camerino, Via Camerini 5, 62032 Camerino (MC), Italy","institution_ids":["https://openalex.org/I112859197"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049828671","display_name":"Claudio Ortenzi","orcid":"https://orcid.org/0000-0002-9051-4085","observed_orcids":["https://orcid.org/0000-0002-9051-4085"]},"institutions":[{"id":"https://openalex.org/I112859197","display_name":"Universit\u00e0 di Camerino","ror":"https://ror.org/0005w8d69","country_code":"IT","type":"education","lineage":["https://openalex.org/I112859197"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Claudio Ortenzi","raw_affiliation_strings":["Dipartimento di Biologia Molecolare Cellulare e Animale, University of Camerino, Via Camerini 5, 62032 Camerino (MC), Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento di Biologia Molecolare Cellulare e Animale, University of Camerino, Via Camerini 5, 62032 Camerino (MC), Italy","institution_ids":["https://openalex.org/I112859197"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113501995","display_name":"Vito Carratore","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210129308","display_name":"Institute of Protein Biochemistry","ror":"https://ror.org/03eqeqg74","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210129308","https://openalex.org/I4210155236"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Vito Carratore","raw_affiliation_strings":["Istituto di Biochimica delle Proteine ed Enzimologia, CNR/IBPE, Via G. Marconi, Naples 80125, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Istituto di Biochimica delle Proteine ed Enzimologia, CNR/IBPE, Via G. Marconi, Naples 80125, Italy","institution_ids":["https://openalex.org/I4210129308"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112487373","display_name":"Pierangelo Luporini","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I112859197","display_name":"Universit\u00e0 di Camerino","ror":"https://ror.org/0005w8d69","country_code":"IT","type":"education","lineage":["https://openalex.org/I112859197"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Pierangelo Luporini","raw_affiliation_strings":["Dipartimento di Biologia Molecolare Cellulare e Animale, University of Camerino, Via Camerini 5, 62032 Camerino (MC), Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento di Biologia Molecolare Cellulare e Animale, University of Camerino, Via Camerini 5, 62032 Camerino (MC), Italy","institution_ids":["https://openalex.org/I112859197"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5112487373"],"corresponding_institution_ids":["https://openalex.org/I112859197"],"apc_list":{"value":3310,"currency":"USD","value_usd":3310},"apc_paid":null,"fwci":0.4713,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.53005182,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"1621","issue":"1","first_page":"17","last_page":"21"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.41019999980926514,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.41019999980926514,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12180","display_name":"Polar Research and Ecology","score":0.2572999894618988,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13326","display_name":"Biochemical and Structural Characterization","score":0.06780000030994415,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antarctic-ciliates","display_name":"Antarctic ciliates","score":0.8190000057220459},{"id":"https://openalex.org/keywords/cold-adaptation","display_name":"cold adaptation","score":0.7960000038146973},{"id":"https://openalex.org/keywords/cysteine-containing-proteins","display_name":"cysteine-containing proteins","score":0.5889999866485596},{"id":"https://openalex.org/keywords/intrachain-disulfide-bonds","display_name":"intrachain disulfide bonds","score":0.9359999895095825},{"id":"https://openalex.org/keywords/protein-hydrophobicity","display_name":"protein hydrophobicity","score":0.6970000267028809},{"id":"https://openalex.org/keywords/solvent-accessibility","display_name":"solvent accessibility","score":0.996999979019165},{"id":"https://openalex.org/keywords/backbone-flexibility","display_name":"backbone flexibility","score":0.9670000076293945}],"concepts":[{"id":"https://openalex.org/C87933860","wikidata":"https://www.wikidata.org/wiki/Q898506","display_name":"Edman degradation","level":4,"score":0.88970947265625},{"id":"https://openalex.org/C2777334866","wikidata":"https://www.wikidata.org/wiki/Q106345","display_name":"Ciliate","level":2,"score":0.7652459144592285},{"id":"https://openalex.org/C2777328355","wikidata":"https://www.wikidata.org/wiki/Q167377","display_name":"Pheromone","level":2,"score":0.718739926815033},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.6478173732757568},{"id":"https://openalex.org/C2775880066","wikidata":"https://www.wikidata.org/wiki/Q186521","display_name":"Threonine","level":4,"score":0.6311161518096924},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5664998888969421},{"id":"https://openalex.org/C2777756961","wikidata":"https://www.wikidata.org/wiki/Q620730","display_name":"Glycine","level":3,"score":0.5543757677078247},{"id":"https://openalex.org/C167625842","wikidata":"https://www.wikidata.org/wiki/Q899763","display_name":"Peptide sequence","level":3,"score":0.5078285336494446},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.49034738540649414},{"id":"https://openalex.org/C10858879","wikidata":"https://www.wikidata.org/wiki/Q899790","display_name":"Signal peptide","level":4,"score":0.4209933280944824},{"id":"https://openalex.org/C64778439","wikidata":"https://www.wikidata.org/wiki/Q7458527","display_name":"Sex pheromone","level":2,"score":0.412354052066803},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.40953949093818665},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.36816054582595825},{"id":"https://openalex.org/C2776414213","wikidata":"https://www.wikidata.org/wiki/Q183290","display_name":"Serine","level":3,"score":0.3144764006137848},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.2214149832725525},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.17483720183372498},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16742822527885437},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.12857210636138916}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000864","descriptor_name":"Antarctic Regions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002918","descriptor_name":"Chymotrypsin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010446","descriptor_name":"Peptide Fragments","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D010675","descriptor_name":"Pheromones","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D010675","descriptor_name":"Pheromones","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015800","descriptor_name":"Protozoan Proteins","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D015800","descriptor_name":"Protozoan Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D016812","descriptor_name":"Euplotes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1016/s0304-4165(03)00011-4","doi":"https://doi.org/10.1016/s0304-4165(03)00011-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0304-4165(03)00011-4","pdf_url":null,"source":{"id":"https://openalex.org/S4210238601","display_name":"Biochimica et Biophysica Acta (BBA) - General Subjects","issn_l":"0304-4165","issn":["0304-4165","1872-8006"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - General Subjects","raw_type":"journal-article"},{"id":"pmid:12667606","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12667606","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et biophysica acta","raw_type":"Comparative Study"},{"id":"pmh:oai:pubblicazioni.unicam.it:11581/115151","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11581/115151","pdf_url":null,"source":{"id":"https://openalex.org/S4306400819","display_name":"Unicam Scientific Publications (University of Camerino)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I112859197","host_organization_name":"Universit\u00e0 di Camerino","host_organization_lineage":["https://openalex.org/I112859197"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:u-pad.unimc.it:11393/35770","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11393/35770","pdf_url":null,"source":{"id":"https://openalex.org/S4377196455","display_name":"U-PAD Unimc - Open Digital Publications (University of Macerata)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I55133342","host_organization_name":"University of Macerata","host_organization_lineage":["https://openalex.org/I55133342"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W1493964527","https://openalex.org/W1581869039","https://openalex.org/W1590768340","https://openalex.org/W1595078586","https://openalex.org/W1971707621","https://openalex.org/W1975304761","https://openalex.org/W1978458479","https://openalex.org/W1980457410","https://openalex.org/W1984547849","https://openalex.org/W1993977185","https://openalex.org/W1997743074","https://openalex.org/W2005080525","https://openalex.org/W2010918394","https://openalex.org/W2015229791","https://openalex.org/W2018891862","https://openalex.org/W2025377293","https://openalex.org/W2030844627","https://openalex.org/W2035146707","https://openalex.org/W2039049597","https://openalex.org/W2041889133","https://openalex.org/W2049204824","https://openalex.org/W2049974299","https://openalex.org/W2055753337","https://openalex.org/W2056911190","https://openalex.org/W2059064121","https://openalex.org/W2059126624","https://openalex.org/W2064560826","https://openalex.org/W2065398981","https://openalex.org/W2065566468","https://openalex.org/W2068945065","https://openalex.org/W2070469372","https://openalex.org/W2072647117","https://openalex.org/W2078413581","https://openalex.org/W2171233622","https://openalex.org/W2322429027","https://openalex.org/W2462140452","https://openalex.org/W4237116547"],"related_works":["https://openalex.org/W2049974299","https://openalex.org/W2041389301","https://openalex.org/W2117410323","https://openalex.org/W2261005386","https://openalex.org/W2077836681","https://openalex.org/W4233256431","https://openalex.org/W2724177292","https://openalex.org/W2076592412","https://openalex.org/W2678602923","https://openalex.org/W2277839600"],"abstract_inverted_index":null,"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}