{"id":"https://openalex.org/W2091328833","doi":"https://doi.org/10.1084/jem.65.5.735","title":"THE PROBABLE NATURE OF THE INFECTIOUS AGENT OF TRACHOMA","display_name":"THE PROBABLE NATURE OF THE INFECTIOUS AGENT OF TRACHOMA","publication_year":1937,"publication_date":"1937-05-01","ids":{"openalex":"https://openalex.org/W2091328833","doi":"https://doi.org/10.1084/jem.65.5.735","mag":"2091328833","pmid":"https://pubmed.ncbi.nlm.nih.gov/19870631","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2133509"},"language":"en","primary_location":{"id":"doi:10.1084/jem.65.5.735","doi":"https://doi.org/10.1084/jem.65.5.735","is_oa":true,"landing_page_url":"https://doi.org/10.1084/jem.65.5.735","pdf_url":"http://jem.rupress.org/content/jem/65/5/735.full.pdf","source":{"id":"https://openalex.org/S22947807","display_name":"The Journal of Experimental Medicine","issn_l":"0022-1007","issn":["0022-1007","1540-9538"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Experimental Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://jem.rupress.org/content/jem/65/5/735.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052499601","display_name":"L. A. Julianelle","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L. A. Julianelle","raw_affiliation_strings":["From the Oscar Johnson Institute, Washington University School of Medicine, St. Louis"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Oscar Johnson Institute, Washington University School of Medicine, St. Louis","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":null,"display_name":"R. W. Harrison","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. W. Harrison","raw_affiliation_strings":["From the Oscar Johnson Institute, Washington University School of Medicine, St. Louis"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Oscar Johnson Institute, Washington University School of Medicine, St. Louis","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109901533","display_name":"M. C. Morris","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. C. Morris","raw_affiliation_strings":["From the Oscar Johnson Institute, Washington University School of Medicine, St. Louis"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Oscar Johnson Institute, Washington University School of Medicine, St. Louis","institution_ids":["https://openalex.org/I204465549"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I204465549"],"apc_list":null,"apc_paid":null,"fwci":25.7237,"has_fulltext":true,"cited_by_count":16,"citation_normalized_percentile":{"value":0.99833333,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":null,"biblio":{"volume":"65","issue":"5","first_page":"735","last_page":"755"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11826","display_name":"Ocular Infections and Treatments","score":0.9589999914169312,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11826","display_name":"Ocular Infections and Treatments","score":0.9589999914169312,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.014499999582767487,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11688","display_name":"Microbial infections and disease research","score":0.003800000064074993,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/trachoma","display_name":"trachoma","score":0.9990000128746033},{"id":"https://openalex.org/keywords/infectious-agents","display_name":"infectious agents","score":0.9179999828338623},{"id":"https://openalex.org/keywords/filterability","display_name":"filterability","score":0.6389999985694885},{"id":"https://openalex.org/keywords/tissue-culture","display_name":"tissue culture","score":0.7170000076293945},{"id":"https://openalex.org/keywords/thermal-inactivation","display_name":"thermal inactivation","score":0.8029999732971191},{"id":"https://openalex.org/keywords/conjunctiva","display_name":"conjunctiva","score":0.6489999890327454},{"id":"https://openalex.org/keywords/bacterial-coinfection","display_name":"bacterial co-infection","score":0.4620000123977661}],"concepts":[{"id":"https://openalex.org/C2777034029","wikidata":"https://www.wikidata.org/wiki/Q193216","display_name":"Trachoma","level":2,"score":0.8772611021995544},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.543308436870575},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.386196106672287},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.38183683156967163},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.38093212246894836},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.19894498586654663}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1084/jem.65.5.735","doi":"https://doi.org/10.1084/jem.65.5.735","is_oa":true,"landing_page_url":"https://doi.org/10.1084/jem.65.5.735","pdf_url":"http://jem.rupress.org/content/jem/65/5/735.full.pdf","source":{"id":"https://openalex.org/S22947807","display_name":"The Journal of Experimental Medicine","issn_l":"0022-1007","issn":["0022-1007","1540-9538"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Experimental Medicine","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2133509","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2133509","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Exp Med","raw_type":"Text"},{"id":"pmid:19870631","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19870631","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of experimental medicine","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.273.8074","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.273.8074","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/7f/99/J_Exp_Med_1937_Apr_30_65(5)_735-755.tar.gz","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1084/jem.65.5.735","doi":"https://doi.org/10.1084/jem.65.5.735","is_oa":true,"landing_page_url":"https://doi.org/10.1084/jem.65.5.735","pdf_url":"http://jem.rupress.org/content/jem/65/5/735.full.pdf","source":{"id":"https://openalex.org/S22947807","display_name":"The Journal of Experimental Medicine","issn_l":"0022-1007","issn":["0022-1007","1540-9538"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Experimental Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.7246000170707703}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2091328833.pdf","grobid_xml":"https://content.openalex.org/works/W2091328833.grobid-xml"},"referenced_works_count":3,"referenced_works":["https://openalex.org/W99153760","https://openalex.org/W1970506992","https://openalex.org/W6813783480"],"related_works":["https://openalex.org/W304128277","https://openalex.org/W2016014050","https://openalex.org/W2007627531","https://openalex.org/W2279225469","https://openalex.org/W1993290783","https://openalex.org/W1964341123","https://openalex.org/W2415029834","https://openalex.org/W2414503641","https://openalex.org/W2171743377","https://openalex.org/W1710101313"],"abstract_inverted_index":{"1.":[0],"The":[1,18,65,126,171],"infectious":[2,19,88,102,164,177],"agent":[3,20,56,89,103,127,165,178],"of":[4,114,122,156,179],"trachoma":[5,55,180],"can":[6],"be":[7,58],"freed":[8,59],"from":[9,60],"extraneous":[10],"bacteria":[11,61],"by":[12,62,130],"passage":[13],"through":[14],"rabbit":[15,44,105],"testicle.":[16],"2.":[17],"multiplies":[21],"little,":[22],"if":[23],"at":[24,152],"all,":[25],"during":[26],"such":[27],"passage,":[28],"but":[29],"in":[30,42,119,166],"many":[31],"instances":[32],"retains":[33],"its":[34],"infectivity":[35],"undiminished.":[36],"3.":[37],"No":[38],"specific":[39,70],"changes":[40],"occur":[41],"the":[43,48,54,83,87,101,120,123,163,176],"testicle":[45],"incidentally":[46],"to":[47,161],"passage.":[49,64],"4.":[50],"On":[51],"rare":[52],"occasion":[53],"may":[57],"intracerebral":[63],"brain":[66],"tissues":[67,99],"show":[68],"no":[69],"reaction.":[71],"5.":[72],"Filtration":[73],"experiments":[74],"with":[75,92,98],"Seitz,":[76],"Kramer,":[77],"Berkefeld,":[78],"and":[79,137,148],"Elford":[80],"filters":[81],"confirm":[82],"general":[84],"observation":[85],"that":[86,175],"is":[90,128,144,181],"filterable":[91],"difficulty.":[93],"6.":[94],"Tissue":[95],"culture":[96],"experiments,":[97],"containing":[100],"(conjunctiva,":[104],"testicle,":[106],"brain,":[107],"etc.),":[108],"conducted":[109],"under":[110],"a":[111,153,182],"wide":[112],"variety":[113],"conditions,":[115],"proved":[116],"uniformly":[117],"unsuccessful":[118],"cultivation":[121],"agent.":[124],"7.":[125],"inactivated":[129],"bile,":[131],"AgNO(3),":[132],"phenol,":[133],"cocaine,":[134],"tartar":[135],"emetic,":[136],"gentian":[138],"violet.":[139],"Its":[140],"heat":[141],"inactivation":[142],"temperature":[143],"between":[145],"45":[146],"degrees":[147,150],"50":[149],"C.,":[151],"time":[154],"interval":[155],"15":[157],"minutes.":[158],"8.":[159],"Attempts":[160],"preserve":[162],"glycerine":[167],"were":[168],"unsuccessful.":[169],"9.":[170],"accumulated":[172],"evidence":[173],"suggests":[174],"virus.":[183]},"counts_by_year":[],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2016-06-24T00:00:00"}