{"id":"https://openalex.org/W2091069207","doi":"https://doi.org/10.1046/j.1460-9568.2002.02185.x","title":"The postnatal reorganization of primary afferent input and dorsal horn cell receptive fields in the rat spinal cord is an activity\u2010dependent process","display_name":"The postnatal reorganization of primary afferent input and dorsal horn cell receptive fields in the rat spinal cord is an activity\u2010dependent process","publication_year":2002,"publication_date":"2002-10-01","ids":{"openalex":"https://openalex.org/W2091069207","doi":"https://doi.org/10.1046/j.1460-9568.2002.02185.x","mag":"2091069207","pmid":"https://pubmed.ncbi.nlm.nih.gov/12405985"},"language":"en","primary_location":{"id":"doi:10.1046/j.1460-9568.2002.02185.x","doi":"https://doi.org/10.1046/j.1460-9568.2002.02185.x","is_oa":true,"landing_page_url":"https://doi.org/10.1046/j.1460-9568.2002.02185.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1046/j.1460-9568.2002.02185.x","source":{"id":"https://openalex.org/S171130801","display_name":"European Journal of Neuroscience","issn_l":"0953-816X","issn":["0953-816X","1460-9568"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Neuroscience","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1046/j.1460-9568.2002.02185.x","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072782296","display_name":"Simon Beggs","orcid":"https://orcid.org/0000-0002-1582-8391","observed_orcids":["https://orcid.org/0000-0002-1582-8391"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Simon Beggs","raw_affiliation_strings":["Department of Anatomy and Developmental Biology, University College London, Gower Street, London WC1E 6BT, United Kingdom","Department of Anatomy and Developmental Biology, University College London, Gower Street, London, WC1E 6BT, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy and Developmental Biology, University College London, Gower Street, London WC1E 6BT, United Kingdom","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Department of Anatomy and Developmental Biology, University College London, Gower Street, London, WC1E 6BT, United Kingdom","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007051405","display_name":"Carole Torsney","orcid":"https://orcid.org/0000-0002-2448-3364","observed_orcids":["https://orcid.org/0000-0002-2448-3364"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Carole Torsney","raw_affiliation_strings":["Department of Anatomy and Developmental Biology, University College London, Gower Street, London WC1E 6BT, United Kingdom","Department of Anatomy and Developmental Biology, University College London, Gower Street, London, WC1E 6BT, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy and Developmental Biology, University College London, Gower Street, London WC1E 6BT, United Kingdom","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Department of Anatomy and Developmental Biology, University College London, Gower Street, London, WC1E 6BT, United Kingdom","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025781788","display_name":"Liam Drew","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Liam J. Drew","raw_affiliation_strings":["Department of Anatomy and Developmental Biology, University College London, Gower Street, London WC1E 6BT, United Kingdom","Department of Anatomy and Developmental Biology, University College London, Gower Street, London, WC1E 6BT, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy and Developmental Biology, University College London, Gower Street, London WC1E 6BT, United Kingdom","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Department of Anatomy and Developmental Biology, University College London, Gower Street, London, WC1E 6BT, United Kingdom","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023674616","display_name":"Maria Fitzgerald","orcid":"https://orcid.org/0000-0003-4188-0123","observed_orcids":["https://orcid.org/0000-0003-4188-0123"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Maria Fitzgerald","raw_affiliation_strings":["Department of Anatomy and Developmental Biology, University College London, Gower Street, London WC1E 6BT, United Kingdom","Department of Anatomy and Developmental Biology, University College London, Gower Street, London, WC1E 6BT, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy and Developmental Biology, University College London, Gower Street, London WC1E 6BT, United Kingdom","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Department of Anatomy and Developmental Biology, University College London, Gower Street, London, WC1E 6BT, United Kingdom","institution_ids":["https://openalex.org/I45129253"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I45129253"],"apc_list":{"value":3560,"currency":"USD","value_usd":3560},"apc_paid":null,"fwci":1.8373,"has_fulltext":true,"cited_by_count":152,"citation_normalized_percentile":{"value":0.8451419,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"16","issue":"7","first_page":"1249","last_page":"1258"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.9086999893188477,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.9086999893188477,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.07750000059604645,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10914","display_name":"Tactile and Sensory Interactions","score":0.007600000128149986,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/postnatal-development","display_name":"postnatal development","score":0.7749999761581421},{"id":"https://openalex.org/keywords/spinal-cord-dorsal-horn","display_name":"dorsal horn","score":0.7590000033378601},{"id":"https://openalex.org/keywords/primary-afferent-input","display_name":"primary afferent input","score":0.6909999847412109},{"id":"https://openalex.org/keywords/nmda-receptor","display_name":"NMDA receptor","score":0.777999997138977},{"id":"https://openalex.org/keywords/mk-801","display_name":"MK-801","score":0.9110000133514404},{"id":"https://openalex.org/keywords/c-fiber-afferents","display_name":"C-fiber afferents","score":0.7239999771118164},{"id":"https://openalex.org/keywords/flexion-reflex","display_name":"flexion reflex","score":0.6940000057220459},{"id":"https://openalex.org/keywords/nociceptive-threshold","display_name":"nociceptive threshold","score":0.7400000095367432},{"id":"https://openalex.org/keywords/rat-spinal-cord","display_name":"rat spinal cord","score":0.48899999260902405}],"concepts":[{"id":"https://openalex.org/C2780775167","wikidata":"https://www.wikidata.org/wiki/Q9606","display_name":"Spinal cord","level":2,"score":0.8348951935768127},{"id":"https://openalex.org/C19071747","wikidata":"https://www.wikidata.org/wiki/Q1755207","display_name":"Receptive field","level":2,"score":0.6827666759490967},{"id":"https://openalex.org/C2909382400","wikidata":"https://www.wikidata.org/wiki/Q9606","display_name":"Lumbar Spinal Cord","level":3,"score":0.5970942974090576},{"id":"https://openalex.org/C67018056","wikidata":"https://www.wikidata.org/wiki/Q414896","display_name":"NMDA receptor","level":3,"score":0.5878684520721436},{"id":"https://openalex.org/C83974742","wikidata":"https://www.wikidata.org/wiki/Q179405","display_name":"Reflex","level":2,"score":0.587772786617279},{"id":"https://openalex.org/C15490471","wikidata":"https://www.wikidata.org/wiki/Q2734305","display_name":"Nociception","level":3,"score":0.5630112886428833},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.545752227306366},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.5370802879333496},{"id":"https://openalex.org/C185263204","wikidata":"https://www.wikidata.org/wiki/Q1154774","display_name":"Electrophysiology","level":2,"score":0.4939492344856262},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4688495397567749},{"id":"https://openalex.org/C44575665","wikidata":"https://www.wikidata.org/wiki/Q1293405","display_name":"Lumbar","level":2,"score":0.4520520865917206},{"id":"https://openalex.org/C94487597","wikidata":"https://www.wikidata.org/wiki/Q11101","display_name":"Sensory system","level":2,"score":0.4406375586986542},{"id":"https://openalex.org/C172659308","wikidata":"https://www.wikidata.org/wiki/Q412542","display_name":"Nociceptor","level":4,"score":0.4351939260959625},{"id":"https://openalex.org/C104211972","wikidata":"https://www.wikidata.org/wiki/Q7067309","display_name":"Noxious stimulus","level":4,"score":0.4340662956237793},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.26706624031066895},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.2466573715209961},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.14914274215698242}],"mesh":[{"descriptor_ui":"D000344","descriptor_name":"Afferent Pathways","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000344","descriptor_name":"Afferent Pathways","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000344","descriptor_name":"Afferent Pathways","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000344","descriptor_name":"Afferent Pathways","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D000344","descriptor_name":"Afferent Pathways","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D000344","descriptor_name":"Afferent Pathways","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D000344","descriptor_name":"Afferent Pathways","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000344","descriptor_name":"Afferent Pathways","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000344","descriptor_name":"Afferent Pathways","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000831","descriptor_name":"Animals, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000831","descriptor_name":"Animals, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000831","descriptor_name":"Animals, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003692","descriptor_name":"Delayed-Action Preparations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003692","descriptor_name":"Delayed-Action Preparations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003692","descriptor_name":"Delayed-Action Preparations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004594","descriptor_name":"Electrophysiology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004594","descriptor_name":"Electrophysiology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004594","descriptor_name":"Electrophysiology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005073","descriptor_name":"Evoked Potentials, Somatosensory","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005073","descriptor_name":"Evoked Potentials, Somatosensory","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005073","descriptor_name":"Evoked Potentials, Somatosensory","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009473","descriptor_name":"Neuronal Plasticity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009473","descriptor_name":"Neuronal Plasticity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009473","descriptor_name":"Neuronal Plasticity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011145","descriptor_name":"Polyvinyls","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011145","descriptor_name":"Polyvinyls","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011145","descriptor_name":"Polyvinyls","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016194","descriptor_name":"Receptors, N-Methyl-D-Aspartate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016194","descriptor_name":"Receptors, N-Methyl-D-Aspartate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016194","descriptor_name":"Receptors, N-Methyl-D-Aspartate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016202","descriptor_name":"N-Methylaspartate","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D016202","descriptor_name":"N-Methylaspartate","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D016202","descriptor_name":"N-Methylaspartate","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D016291","descriptor_name":"Dizocilpine Maleate","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D016291","descriptor_name":"Dizocilpine Maleate","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D016291","descriptor_name":"Dizocilpine Maleate","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D018691","descriptor_name":"Excitatory Amino Acid Antagonists","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D018691","descriptor_name":"Excitatory Amino Acid Antagonists","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D018691","descriptor_name":"Excitatory Amino Acid Antagonists","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D020671","descriptor_name":"Posterior Horn Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D020671","descriptor_name":"Posterior Horn Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D020671","descriptor_name":"Posterior Horn Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D020671","descriptor_name":"Posterior Horn Cells","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D020671","descriptor_name":"Posterior Horn Cells","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D020671","descriptor_name":"Posterior Horn Cells","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D020671","descriptor_name":"Posterior Horn Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D020671","descriptor_name":"Posterior Horn Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D020671","descriptor_name":"Posterior Horn Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D036421","descriptor_name":"Nerve Fibers, Unmyelinated","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D036421","descriptor_name":"Nerve Fibers, Unmyelinated","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D036421","descriptor_name":"Nerve Fibers, Unmyelinated","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D036421","descriptor_name":"Nerve Fibers, Unmyelinated","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D036421","descriptor_name":"Nerve Fibers, Unmyelinated","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D036421","descriptor_name":"Nerve Fibers, Unmyelinated","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1046/j.1460-9568.2002.02185.x","doi":"https://doi.org/10.1046/j.1460-9568.2002.02185.x","is_oa":true,"landing_page_url":"https://doi.org/10.1046/j.1460-9568.2002.02185.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1046/j.1460-9568.2002.02185.x","source":{"id":"https://openalex.org/S171130801","display_name":"European Journal of Neuroscience","issn_l":"0953-816X","issn":["0953-816X","1460-9568"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Neuroscience","raw_type":"journal-article"},{"id":"pmid:12405985","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12405985","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The European journal of neuroscience","raw_type":"Journal Article"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:121713","doi":null,"is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/121713/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"EUR J NEUROSCI , 16 (7) 1249 - 1258. (2002)","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1046/j.1460-9568.2002.02185.x","doi":"https://doi.org/10.1046/j.1460-9568.2002.02185.x","is_oa":true,"landing_page_url":"https://doi.org/10.1046/j.1460-9568.2002.02185.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1046/j.1460-9568.2002.02185.x","source":{"id":"https://openalex.org/S171130801","display_name":"European Journal of Neuroscience","issn_l":"0953-816X","issn":["0953-816X","1460-9568"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Neuroscience","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.6240000128746033,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2091069207.pdf","grobid_xml":"https://content.openalex.org/works/W2091069207.grobid-xml"},"referenced_works_count":57,"referenced_works":["https://openalex.org/W146914657","https://openalex.org/W1503057316","https://openalex.org/W1548233628","https://openalex.org/W1603926526","https://openalex.org/W1667361580","https://openalex.org/W1783254105","https://openalex.org/W1805286350","https://openalex.org/W1852230543","https://openalex.org/W1963806203","https://openalex.org/W1963989698","https://openalex.org/W1970324625","https://openalex.org/W1972764278","https://openalex.org/W1974622571","https://openalex.org/W1976860452","https://openalex.org/W1977622088","https://openalex.org/W1985043644","https://openalex.org/W1989670552","https://openalex.org/W1993877941","https://openalex.org/W1994209780","https://openalex.org/W1995679813","https://openalex.org/W2003404396","https://openalex.org/W2005660590","https://openalex.org/W2008566814","https://openalex.org/W2012540168","https://openalex.org/W2013902161","https://openalex.org/W2014007136","https://openalex.org/W2015757835","https://openalex.org/W2017213222","https://openalex.org/W2023215189","https://openalex.org/W2026186914","https://openalex.org/W2027545565","https://openalex.org/W2029980589","https://openalex.org/W2044202654","https://openalex.org/W2047113736","https://openalex.org/W2053513632","https://openalex.org/W2057050792","https://openalex.org/W2061811637","https://openalex.org/W2063170472","https://openalex.org/W2065104375","https://openalex.org/W2071715238","https://openalex.org/W2074382776","https://openalex.org/W2076765847","https://openalex.org/W2079404537","https://openalex.org/W2082477901","https://openalex.org/W2085711502","https://openalex.org/W2086237038","https://openalex.org/W2093611477","https://openalex.org/W2094043543","https://openalex.org/W2106370293","https://openalex.org/W2108841190","https://openalex.org/W2129766810","https://openalex.org/W2136999245","https://openalex.org/W2138716494","https://openalex.org/W2158126393","https://openalex.org/W2171697328","https://openalex.org/W2321643402","https://openalex.org/W2341704959"],"related_works":["https://openalex.org/W2492915263","https://openalex.org/W2142345378","https://openalex.org/W2289556302","https://openalex.org/W2413179330","https://openalex.org/W2013326835","https://openalex.org/W3206832263","https://openalex.org/W2025426835","https://openalex.org/W1867755896","https://openalex.org/W1976863938","https://openalex.org/W1975785408"],"abstract_inverted_index":{"The":[0,147,207],"dorsal":[1,71,174],"horn":[2,72,96,175],"of":[3,20,31,56,69,73,92,106,140,150,192,218],"the":[4,8,39,49,59,70,74,79,86,136,144,173,193,211,223],"spinal":[5,76,99,145,224],"cord":[6,77,225],"in":[7,51,98,109,143,162,172],"newborn":[9],"rat":[10],"is":[11,226],"characterized":[12],"by":[13,108],"large":[14],"cutaneous":[15,52,116],"mechanoreceptive":[16,117],"fields,":[17],"a":[18],"predominance":[19],"A-fibre":[21,28,93,121,141,153,219],"synaptic":[22],"inputs":[23],"and":[24,36,89,119,169,198,215],"diffuse":[25],"primary":[26,154],"afferent":[27,167],"projections,":[29],"all":[30],"which":[32],"are":[33],"gradually":[34],"reduced":[35,185],"refined":[37],"over":[38,58],"first":[40],"postnatal":[41,60,148,213],"weeks.":[42],"This":[43],"may":[44],"be":[45],"partly":[46],"responsible":[47],"for":[48],"reduction":[50],"flexion":[53],"reflex":[54,187],"sensitivity":[55],"rats":[57],"period.":[61],"Here":[62],"we":[63],"show":[64],"that":[65,210],"chronic,":[66],"local":[67],"exposure":[68],"lumbar":[75],"to":[78,156,189,196],"NMDA":[80,231],"antagonist":[81],"MK801":[82,133],"from":[83],"birth":[84],"prevents":[85],"normal":[87,137,212],"functional":[88,216],"structural":[90,138,214],"reorganization":[91,139],"connections.":[94],"Dorsal":[95],"cells":[97],"MK801-treated":[100,180],"animals,":[101,200],"investigated":[102],"at":[103],"eight":[104],"weeks":[105],"age":[107],"vivo":[110],"electrophysiological":[111],"recording,":[112],"had":[113,183],"significantly":[114,184],"larger":[115],"fields":[118],"greater":[120],"evoked":[122,128],"responses":[123,129],"than":[124],"vehicle":[125],"controls.":[126],"C-fibre":[127,166],"were":[130,176],"unaffected.":[131,178,206],"Chronic":[132],"also":[134,182],"prevented":[135],"terminals":[142,168],"cord.":[146],"withdrawal":[149],"superficially":[151],"projecting":[152],"afferents":[155],"deeper":[157],"laminae":[158],"did":[159],"not":[160],"occur":[161],"treated":[163],"animals":[164,181],"although":[165],"cell":[170],"density":[171],"apparently":[177],"Spinal":[179],"behavioural":[186],"thresholds":[188,204],"mechanical":[190],"stimulation":[191],"hindpaw":[194],"compared":[195],"na\u00efve":[197],"vehicle-treated":[199],"whereas":[201],"noxious":[202],"heat":[203],"remained":[205],"results":[208],"indicate":[209],"development":[217],"sensory":[220],"connectivity":[221],"within":[222],"an":[227],"activity-dependent":[228],"process":[229],"requiring":[230],"receptor":[232],"activation.":[233]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":10},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":11},{"year":2012,"cited_by_count":11}],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2025-10-10T00:00:00"}