{"id":"https://openalex.org/W2090959366","doi":"https://doi.org/10.1016/s0014-2999(97)01241-7","title":"Comparison of the antiplatelet effect of YM337 and abciximab in rhesus monkeys","display_name":"Comparison of the antiplatelet effect of YM337 and abciximab in rhesus monkeys","publication_year":1997,"publication_date":"1997-10-01","ids":{"openalex":"https://openalex.org/W2090959366","doi":"https://doi.org/10.1016/s0014-2999(97)01241-7","mag":"2090959366","pmid":"https://pubmed.ncbi.nlm.nih.gov/9384230"},"language":"en","primary_location":{"id":"doi:10.1016/s0014-2999(97)01241-7","doi":"https://doi.org/10.1016/s0014-2999(97)01241-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0014-2999(97)01241-7","pdf_url":null,"source":{"id":"https://openalex.org/S187816532","display_name":"European Journal of Pharmacology","issn_l":"0014-2999","issn":["0014-2999","1879-0712"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Pharmacology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103381928","display_name":"Kenichi Suzuki","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Ken-ichi Suzuki","raw_affiliation_strings":["Institute for Drug Discovery Research, Yamanouchi Pharmaceutical, Tsukuba, Ibaraki, Japan. suzuki_k@yamanouchi.co.jp","Institute for Drug Discovery Research, Yamanouchi Pharmaceutical, Tsukuba, Ibaraki, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Drug Discovery Research, Yamanouchi Pharmaceutical, Tsukuba, Ibaraki, Japan. suzuki_k@yamanouchi.co.jp","institution_ids":[]},{"raw_affiliation_string":"Institute for Drug Discovery Research, Yamanouchi Pharmaceutical, Tsukuba, Ibaraki, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110166018","display_name":"Yumiko Sakai","orcid":"https://orcid.org/0000-0003-2657-7716","observed_orcids":["https://orcid.org/0000-0003-2657-7716"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yumiko Sakai","raw_affiliation_strings":["Institute for Drug Discovery Research, Yamanouchi Pharmaceutical, 21 Miyukigaoka, Tsukuba, Ibaraki 305, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Drug Discovery Research, Yamanouchi Pharmaceutical, 21 Miyukigaoka, Tsukuba, Ibaraki 305, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043704421","display_name":"Nami Hisamichi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nami Hisamichi","raw_affiliation_strings":["Institute for Drug Discovery Research, Yamanouchi Pharmaceutical, 21 Miyukigaoka, Tsukuba, Ibaraki 305, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Drug Discovery Research, Yamanouchi Pharmaceutical, 21 Miyukigaoka, Tsukuba, Ibaraki 305, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109366616","display_name":"Yuta Taniuchi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yuta Taniuchi","raw_affiliation_strings":["Institute for Drug Discovery Research, Yamanouchi Pharmaceutical, 21 Miyukigaoka, Tsukuba, Ibaraki 305, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Drug Discovery Research, Yamanouchi Pharmaceutical, 21 Miyukigaoka, Tsukuba, Ibaraki 305, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105356564","display_name":"Kazuo Sato","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kazuo Sato","raw_affiliation_strings":["Institute for Drug Discovery Research, Yamanouchi Pharmaceutical, 21 Miyukigaoka, Tsukuba, Ibaraki 305, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Drug Discovery Research, Yamanouchi Pharmaceutical, 21 Miyukigaoka, Tsukuba, Ibaraki 305, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002766649","display_name":"Chinami Terazaki","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chinami Terazaki","raw_affiliation_strings":["Institute for Drug Discovery Research, Yamanouchi Pharmaceutical, 21 Miyukigaoka, Tsukuba, Ibaraki 305, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Drug Discovery Research, Yamanouchi Pharmaceutical, 21 Miyukigaoka, Tsukuba, Ibaraki 305, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062104011","display_name":"Seiji Kaku","orcid":"https://orcid.org/0000-0002-7861-5545","observed_orcids":["https://orcid.org/0000-0002-7861-5545"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Seiji Kaku","raw_affiliation_strings":["Institute for Drug Discovery Research, Yamanouchi Pharmaceutical, 21 Miyukigaoka, Tsukuba, Ibaraki 305, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Drug Discovery Research, Yamanouchi Pharmaceutical, 21 Miyukigaoka, Tsukuba, Ibaraki 305, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041324376","display_name":"Tomihisa Kawasaki","orcid":"https://orcid.org/0000-0001-6050-5893","observed_orcids":["https://orcid.org/0000-0001-6050-5893"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tomihisa Kawasaki","raw_affiliation_strings":["Institute for Drug Discovery Research, Yamanouchi Pharmaceutical, 21 Miyukigaoka, Tsukuba, Ibaraki 305, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Drug Discovery Research, Yamanouchi Pharmaceutical, 21 Miyukigaoka, Tsukuba, Ibaraki 305, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028109593","display_name":"Shinya Yano","orcid":"https://orcid.org/0000-0001-6701-3007","observed_orcids":["https://orcid.org/0000-0001-6701-3007"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shinya Yano","raw_affiliation_strings":["Institute for Drug Discovery Research, Yamanouchi Pharmaceutical, 21 Miyukigaoka, Tsukuba, Ibaraki 305, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Drug Discovery Research, Yamanouchi Pharmaceutical, 21 Miyukigaoka, Tsukuba, Ibaraki 305, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019154004","display_name":"Osamu Inagaki","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Osamu Inagaki","raw_affiliation_strings":["Institute for Drug Discovery Research, Yamanouchi Pharmaceutical, 21 Miyukigaoka, Tsukuba, Ibaraki 305, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Drug Discovery Research, Yamanouchi Pharmaceutical, 21 Miyukigaoka, Tsukuba, Ibaraki 305, Japan","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111600306","display_name":"Yasuhiko Masuho","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yasuhiko Masuho","raw_affiliation_strings":["Institute for Drug Discovery Research, Yamanouchi Pharmaceutical, 21 Miyukigaoka, Tsukuba, Ibaraki 305, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Drug Discovery Research, Yamanouchi Pharmaceutical, 21 Miyukigaoka, Tsukuba, Ibaraki 305, Japan","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5103381928"],"corresponding_institution_ids":[],"apc_list":{"value":3230,"currency":"USD","value_usd":3230},"apc_paid":null,"fwci":0.5559,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.66404382,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"336","issue":"2-3","first_page":"169","last_page":"176"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10746","display_name":"Platelet Disorders and Treatments","score":0.8320000171661377,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10746","display_name":"Platelet Disorders and Treatments","score":0.8320000171661377,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11064","display_name":"Antiplatelet Therapy and Cardiovascular Diseases","score":0.1527000069618225,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.0071000000461936,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/abciximab","display_name":"abciximab","score":0.9679999947547913},{"id":"https://openalex.org/keywords/antiplatelet-drugs","display_name":"antiplatelet agents","score":0.8270000219345093},{"id":"https://openalex.org/keywords/platelet-inhibition","display_name":"platelet aggregation inhibition","score":0.9750000238418579},{"id":"https://openalex.org/keywords/humanized-antibody","display_name":"humanized monoclonal antibody","score":0.7979999780654907},{"id":"https://openalex.org/keywords/chimeric-monoclonal-antibody","display_name":"chimeric monoclonal antibody","score":0.871999979019165},{"id":"https://openalex.org/keywords/therapeutic-window","display_name":"therapeutic window","score":0.6679999828338623},{"id":"https://openalex.org/keywords/rhesus-macaques","display_name":"rhesus monkeys","score":0.6449999809265137},{"id":"https://openalex.org/keywords/continuous-infusion","display_name":"continuous infusion","score":0.5299999713897705}],"concepts":[{"id":"https://openalex.org/C2777871224","wikidata":"https://www.wikidata.org/wiki/Q307088","display_name":"Abciximab","level":4,"score":0.9604430198669434},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.7221431136131287},{"id":"https://openalex.org/C2779216453","wikidata":"https://www.wikidata.org/wiki/Q489957","display_name":"Bleeding time","level":4,"score":0.6676766872406006},{"id":"https://openalex.org/C43376680","wikidata":"https://www.wikidata.org/wiki/Q6580786","display_name":"Bolus (digestion)","level":2,"score":0.5952094793319702},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5939276218414307},{"id":"https://openalex.org/C2993802102","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet aggregation","level":3,"score":0.5441527962684631},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5320908427238464},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.23839136958122253},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.05770242214202881},{"id":"https://openalex.org/C45393284","wikidata":"https://www.wikidata.org/wiki/Q191012","display_name":"Conventional PCI","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000077284","descriptor_name":"Abciximab","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D001760","descriptor_name":"Bleeding Time","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007140","descriptor_name":"Immunoglobulin Fab Fragments","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D007262","descriptor_name":"Infusions, Intravenous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007275","descriptor_name":"Injections, Intravenous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008253","descriptor_name":"Macaca mulatta","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010974","descriptor_name":"Platelet Aggregation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D010975","descriptor_name":"Platelet Aggregation Inhibitors","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D010975","descriptor_name":"Platelet Aggregation Inhibitors","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D019039","descriptor_name":"Platelet Glycoprotein GPIIb-IIIa Complex","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0014-2999(97)01241-7","doi":"https://doi.org/10.1016/s0014-2999(97)01241-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0014-2999(97)01241-7","pdf_url":null,"source":{"id":"https://openalex.org/S187816532","display_name":"European Journal of Pharmacology","issn_l":"0014-2999","issn":["0014-2999","1879-0712"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Pharmacology","raw_type":"journal-article"},{"id":"pmid:9384230","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9384230","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of pharmacology","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W3880031","https://openalex.org/W1007489501","https://openalex.org/W1516954810","https://openalex.org/W1518372943","https://openalex.org/W1552868989","https://openalex.org/W1594700207","https://openalex.org/W1602418150","https://openalex.org/W1901030926","https://openalex.org/W1988504835","https://openalex.org/W2012330153","https://openalex.org/W2017757446","https://openalex.org/W2029231027","https://openalex.org/W2039404414","https://openalex.org/W2043503971","https://openalex.org/W2052899600","https://openalex.org/W2053917461","https://openalex.org/W2078253165","https://openalex.org/W2080109954","https://openalex.org/W2099250201","https://openalex.org/W2152307503","https://openalex.org/W2170352750","https://openalex.org/W2173890895","https://openalex.org/W2240331751","https://openalex.org/W2274031374","https://openalex.org/W2398780564","https://openalex.org/W2406240481","https://openalex.org/W2423281944","https://openalex.org/W3022148767","https://openalex.org/W4239471829","https://openalex.org/W4324114048","https://openalex.org/W6635654501","https://openalex.org/W6694484212"],"related_works":["https://openalex.org/W2398780564","https://openalex.org/W2115013476","https://openalex.org/W2000425963","https://openalex.org/W2810510606","https://openalex.org/W2103622917","https://openalex.org/W2061298133","https://openalex.org/W2032296829","https://openalex.org/W2411781883","https://openalex.org/W2161125864","https://openalex.org/W2211113369"],"abstract_inverted_index":null,"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}