{"id":"https://openalex.org/W2090945178","doi":"https://doi.org/10.1002/ijc.26187","title":"MUC4: A novel prognostic factor of oral squamous cell carcinoma","display_name":"MUC4: A novel prognostic factor of oral squamous cell carcinoma","publication_year":2011,"publication_date":"2011-05-26","ids":{"openalex":"https://openalex.org/W2090945178","doi":"https://doi.org/10.1002/ijc.26187","mag":"2090945178","pmid":"https://pubmed.ncbi.nlm.nih.gov/21618516"},"language":"en","primary_location":{"id":"doi:10.1002/ijc.26187","doi":"https://doi.org/10.1002/ijc.26187","is_oa":true,"landing_page_url":"https://doi.org/10.1002/ijc.26187","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijc.26187","source":{"id":"https://openalex.org/S5382288","display_name":"International Journal of Cancer","issn_l":"0020-7136","issn":["0020-7136","1097-0215"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Cancer","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijc.26187","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103050013","display_name":"Tomofumi Hamada","orcid":"https://orcid.org/0000-0003-2746-3964","observed_orcids":["https://orcid.org/0000-0003-2746-3964"]},"institutions":[{"id":"https://openalex.org/I4210119230","display_name":"Kagoshima University Hospital","ror":"https://ror.org/02dkdym27","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210119230"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Tomofumi Hamada","raw_affiliation_strings":["Department of Oral Surgery, Kagoshima University Hospital, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan. thamada@dent.kagoshima-u.ac.jp","Department of Oral Surgery, Kagoshima University Hospital, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan","Tel: +81-99-275-6232,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral Surgery, Kagoshima University Hospital, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan. thamada@dent.kagoshima-u.ac.jp","institution_ids":["https://openalex.org/I4210119230"]},{"raw_affiliation_string":"Department of Oral Surgery, Kagoshima University Hospital, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan","institution_ids":["https://openalex.org/I4210119230"]},{"raw_affiliation_string":"Tel: +81-99-275-6232,","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Tsunenobu Wakamatsu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107139324","display_name":"Kagoshima University","ror":"https://ror.org/03ss88z23","country_code":"JP","type":"education","lineage":["https://openalex.org/I107139324"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tsunenobu Wakamatsu","raw_affiliation_strings":["Department of Maxillofacial Diagnostic and Surgical Science, Field of Oral and Maxillofacial Rehabilitation, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan","T.H. and T.W. contributed equally to this work"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Maxillofacial Diagnostic and Surgical Science, Field of Oral and Maxillofacial Rehabilitation, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan","institution_ids":["https://openalex.org/I107139324"]},{"raw_affiliation_string":"T.H. and T.W. contributed equally to this work","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017099827","display_name":"Mayumi Miyahara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107139324","display_name":"Kagoshima University","ror":"https://ror.org/03ss88z23","country_code":"JP","type":"education","lineage":["https://openalex.org/I107139324"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mayumi Miyahara","raw_affiliation_strings":["Department of Maxillofacial Diagnostic and Surgical Science, Field of Oral and Maxillofacial Rehabilitation, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Maxillofacial Diagnostic and Surgical Science, Field of Oral and Maxillofacial Rehabilitation, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan","institution_ids":["https://openalex.org/I107139324"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Satoshi Nagata","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107139324","display_name":"Kagoshima University","ror":"https://ror.org/03ss88z23","country_code":"JP","type":"education","lineage":["https://openalex.org/I107139324"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Satoshi Nagata","raw_affiliation_strings":["Department of Maxillofacial Diagnostic and Surgical Science, Field of Oral and Maxillofacial Rehabilitation, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Maxillofacial Diagnostic and Surgical Science, Field of Oral and Maxillofacial Rehabilitation, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan","institution_ids":["https://openalex.org/I107139324"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Masahiro Nomura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107139324","display_name":"Kagoshima University","ror":"https://ror.org/03ss88z23","country_code":"JP","type":"education","lineage":["https://openalex.org/I107139324"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masahiro Nomura","raw_affiliation_strings":["Department of Maxillofacial Diagnostic and Surgical Science, Field of Oral and Maxillofacial Rehabilitation, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Maxillofacial Diagnostic and Surgical Science, Field of Oral and Maxillofacial Rehabilitation, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan","institution_ids":["https://openalex.org/I107139324"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016889753","display_name":"Yoshiaki Kamikawa","orcid":"https://orcid.org/0000-0001-8088-4819","observed_orcids":["https://orcid.org/0000-0001-8088-4819"]},"institutions":[{"id":"https://openalex.org/I4210119230","display_name":"Kagoshima University Hospital","ror":"https://ror.org/02dkdym27","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210119230"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshiaki Kamikawa","raw_affiliation_strings":["Department of Oral Surgery, Kagoshima University Hospital, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral Surgery, Kagoshima University Hospital, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan","institution_ids":["https://openalex.org/I4210119230"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109033442","display_name":"Norishige Yamada","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107139324","display_name":"Kagoshima University","ror":"https://ror.org/03ss88z23","country_code":"JP","type":"education","lineage":["https://openalex.org/I107139324"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Norishige Yamada","raw_affiliation_strings":["Department of Human Pathology, Field of Oncology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Human Pathology, Field of Oncology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan","institution_ids":["https://openalex.org/I107139324"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109225893","display_name":"Surinder K. Batra","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I59130452","display_name":"University of Nebraska Medical Center","ror":"https://ror.org/00thqtb16","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I59130452"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Surinder K. Batra","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, 985870 Nebraska Medical Center, Omaha, NE 68198-5870"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, 985870 Nebraska Medical Center, Omaha, NE 68198-5870","institution_ids":["https://openalex.org/I59130452"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112503305","display_name":"Suguru Yonezawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107139324","display_name":"Kagoshima University","ror":"https://ror.org/03ss88z23","country_code":"JP","type":"education","lineage":["https://openalex.org/I107139324"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Suguru Yonezawa","raw_affiliation_strings":["Department of Human Pathology, Field of Oncology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Human Pathology, Field of Oncology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan","institution_ids":["https://openalex.org/I107139324"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084660769","display_name":"Kazumasa SUGIHARA","orcid":"https://orcid.org/0000-0003-4797-100X","observed_orcids":["https://orcid.org/0000-0003-4797-100X"]},"institutions":[{"id":"https://openalex.org/I107139324","display_name":"Kagoshima University","ror":"https://ror.org/03ss88z23","country_code":"JP","type":"education","lineage":["https://openalex.org/I107139324"]},{"id":"https://openalex.org/I4210119230","display_name":"Kagoshima University Hospital","ror":"https://ror.org/02dkdym27","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210119230"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazumasa Sugihara","raw_affiliation_strings":["Department of Maxillofacial Diagnostic and Surgical Science, Field of Oral and Maxillofacial Rehabilitation, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan","Department of Oral Surgery, Kagoshima University Hospital, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Maxillofacial Diagnostic and Surgical Science, Field of Oral and Maxillofacial Rehabilitation, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan","institution_ids":["https://openalex.org/I107139324"]},{"raw_affiliation_string":"Department of Oral Surgery, Kagoshima University Hospital, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan","institution_ids":["https://openalex.org/I4210119230"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5103050013"],"corresponding_institution_ids":["https://openalex.org/I4210119230"],"apc_list":{"value":5030,"currency":"USD","value_usd":5030},"apc_paid":null,"fwci":5.4318,"has_fulltext":true,"cited_by_count":51,"citation_normalized_percentile":{"value":0.96337224,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"130","issue":"8","first_page":"1768","last_page":"1776"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9336000084877014,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9336000084877014,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.03060000017285347,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":0.005400000140070915,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oral-squamous-cell-carcinoma","display_name":"oral squamous cell carcinoma","score":0.9980000257492065},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.8870000243186951},{"id":"https://openalex.org/keywords/tumor-invasion","display_name":"tumor invasion","score":0.6899999976158142},{"id":"https://openalex.org/keywords/lymph-node-metastasis","display_name":"lymph node metastasis","score":0.8539999723434448},{"id":"https://openalex.org/keywords/local-recurrence","display_name":"local recurrence","score":0.9409999847412109},{"id":"https://openalex.org/keywords/disease-free-survival","display_name":"disease-free survival","score":0.7979999780654907},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.9769999980926514},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.7710000276565552}],"concepts":[{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.6317099332809448},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5958019495010376},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.5635820627212524},{"id":"https://openalex.org/C179264091","wikidata":"https://www.wikidata.org/wiki/Q410862","display_name":"Mucin","level":2,"score":0.5585830807685852},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5495339035987854},{"id":"https://openalex.org/C3019992690","wikidata":"https://www.wikidata.org/wiki/Q92767510","display_name":"Basal cell","level":2,"score":0.5252630114555359},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5194841623306274},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.48784637451171875},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.4714837074279785},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.4288294315338135},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.41739600896835327},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.24742832779884338},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004848","descriptor_name":"Epithelium","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004848","descriptor_name":"Epithelium","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009061","descriptor_name":"Mouth Mucosa","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009061","descriptor_name":"Mouth Mucosa","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D009062","descriptor_name":"Mouth Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D009062","descriptor_name":"Mouth Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D015999","descriptor_name":"Multivariate Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053208","descriptor_name":"Kaplan-Meier Estimate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055264","descriptor_name":"Mucin-4","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1002/ijc.26187","doi":"https://doi.org/10.1002/ijc.26187","is_oa":true,"landing_page_url":"https://doi.org/10.1002/ijc.26187","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijc.26187","source":{"id":"https://openalex.org/S5382288","display_name":"International Journal of Cancer","issn_l":"0020-7136","issn":["0020-7136","1097-0215"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Cancer","raw_type":"journal-article"},{"id":"pmid:21618516","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21618516","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of cancer","raw_type":"Journal Article"},{"id":"mag:2978646454","doi":null,"is_oa":false,"landing_page_url":"http://ci.nii.ac.jp/naid/500000576715","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.1002/ijc.26187","doi":"https://doi.org/10.1002/ijc.26187","is_oa":true,"landing_page_url":"https://doi.org/10.1002/ijc.26187","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijc.26187","source":{"id":"https://openalex.org/S5382288","display_name":"International Journal of Cancer","issn_l":"0020-7136","issn":["0020-7136","1097-0215"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Cancer","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G6786399984","display_name":"Expression of MUC1 splicing variants and its relationship with clinicopathological factors in oral squamous cell carcinoma.","funder_award_id":"21792020","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G6863049964","display_name":null,"funder_award_id":"219447","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G7860235936","display_name":"Membranous mucin expression in oral squamous cell carcinoma and its clinical significance","funder_award_id":"23390466","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2090945178.pdf","grobid_xml":"https://content.openalex.org/works/W2090945178.grobid-xml"},"referenced_works_count":51,"referenced_works":["https://openalex.org/W1496993956","https://openalex.org/W1536690700","https://openalex.org/W1540454282","https://openalex.org/W1836258472","https://openalex.org/W1967930627","https://openalex.org/W1968098999","https://openalex.org/W1972341325","https://openalex.org/W1973445950","https://openalex.org/W1973793754","https://openalex.org/W1976435347","https://openalex.org/W1982081954","https://openalex.org/W1984025643","https://openalex.org/W1988950290","https://openalex.org/W1992087250","https://openalex.org/W1998915751","https://openalex.org/W2001805903","https://openalex.org/W2001882511","https://openalex.org/W2004009058","https://openalex.org/W2006104546","https://openalex.org/W2008037959","https://openalex.org/W2012744533","https://openalex.org/W2014037052","https://openalex.org/W2019388333","https://openalex.org/W2020830322","https://openalex.org/W2030048504","https://openalex.org/W2044243609","https://openalex.org/W2050484748","https://openalex.org/W2055699697","https://openalex.org/W2063896912","https://openalex.org/W2069920887","https://openalex.org/W2074774097","https://openalex.org/W2083495092","https://openalex.org/W2086760843","https://openalex.org/W2090930451","https://openalex.org/W2103953318","https://openalex.org/W2104550930","https://openalex.org/W2106787323","https://openalex.org/W2109120261","https://openalex.org/W2132099830","https://openalex.org/W2138216676","https://openalex.org/W2146797845","https://openalex.org/W2148688801","https://openalex.org/W2150312232","https://openalex.org/W2150999652","https://openalex.org/W2151607890","https://openalex.org/W2151795469","https://openalex.org/W2153359367","https://openalex.org/W2156913035","https://openalex.org/W2161497232","https://openalex.org/W2168640625","https://openalex.org/W2172986177"],"related_works":["https://openalex.org/W2010688378","https://openalex.org/W7222884002","https://openalex.org/W2319440673","https://openalex.org/W7208250763","https://openalex.org/W2969819302","https://openalex.org/W1573106543","https://openalex.org/W2562028509","https://openalex.org/W4377940783","https://openalex.org/W3048875572","https://openalex.org/W4390539902"],"abstract_inverted_index":{"MUC4":[0,19,54,64,81,92,136,162,193,201,213,239,258],"mucin":[1],"is":[2,21,47,241],"now":[3],"known":[4],"to":[5,48,173],"be":[6,174,261],"expressed":[7,83],"in":[8,26,36,56,65,76,84,130,183,227],"various":[9],"normal":[10],"and":[11,124,146,167,187,206,223,232],"cancer":[12,119],"tissues.":[13],"We":[14,58,236],"have":[15],"previously":[16],"reported":[17],"that":[18,135],"expression":[20,55,61,93,137,163,194,202,214,259],"a":[22,216],"novel":[23],"prognostic":[24,51,74],"factor":[25,219,244],"several":[27],"malignant":[28],"tumors;":[29],"however,":[30],"it":[31],"has":[32],"not":[33],"been":[34],"investigated":[35],"oral":[37],"squamous":[38],"cell":[39],"carcinoma":[40],"(OSCC).":[41],"The":[42,185],"aim":[43],"of":[44,53,63,86,118,180,190,248],"our":[45],"study":[46],"evaluate":[49],"the":[50,60,87,212],"significance":[52,75],"OSCC.":[57,91,131,184],"examined":[59],"profile":[62],"OSCC":[66,77,228,255],"tissues":[67],"from":[68],"150":[69,88],"patients":[70,89,191,249,253],"using":[71],"immunohistochemistry.":[72],"Its":[73],"was":[78,82,94,195,215],"statistically":[79,153,175],"analyzed.":[80],"61":[85],"with":[90,97,192,250,254],"significantly":[95,196],"correlated":[96],"higher":[98],"T":[99],"classification":[100],"(p":[101,107,113,121,127,138,143,149,164,170,203,229],"=":[102,108,114,122,128,139,144,150,165,171,208,230,234],"0.0004),":[103],"positive":[104,257],"nodal":[105,225],"metastasis":[106,226],"0.049),":[109],"advanced":[110],"tumor":[111,141],"stage":[112],"0.002),":[115],"diffuse":[116,147,168],"invasion":[117,148,169],"cells":[120],"0.004)":[123,129],"patient's":[125],"death":[126],"Multivariate":[132],"analysis":[133,160],"showed":[134],"0.011),":[140],"location":[142],"0.032)":[145],"0.009)":[151],"were":[152],"significant":[154,176,217],"risk":[155,178,218],"factors.":[156],"Backward":[157],"stepwise":[158],"multivariate":[159],"demonstrated":[161],"0.0015)":[166],"0.018)":[172],"independent":[177,243],"factors":[179],"poor":[181,246],"survival":[182,189],"disease-free":[186],"overall":[188],"worse":[197],"than":[198],"those":[199],"without":[200],"<":[204],"0.0001":[205],"p":[207,233],"0.0001).":[209,235],"In":[210],"addition,":[211],"for":[220,245],"local":[221],"recurrence":[222],"subsequent":[224],"0.017":[231],"first":[237],"report":[238],"overexpression":[240],"an":[242],"prognosis":[247],"OSCC;":[251],"therefore,":[252],"showing":[256],"should":[260],"followed":[262],"up":[263],"carefully.":[264]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}