{"id":"https://openalex.org/W2090935883","doi":"https://doi.org/10.1097/ta.0b013e31825aa9ea","title":"Does treatment of split-thickness skin grafts with negative-pressure wound therapy improve tissue markers of wound healing in a porcine experimental model?","display_name":"Does treatment of split-thickness skin grafts with negative-pressure wound therapy improve tissue markers of wound healing in a porcine experimental model?","publication_year":2012,"publication_date":"2012-07-28","ids":{"openalex":"https://openalex.org/W2090935883","doi":"https://doi.org/10.1097/ta.0b013e31825aa9ea","mag":"2090935883","pmid":"https://pubmed.ncbi.nlm.nih.gov/22846954","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3698483"},"language":"en","primary_location":{"id":"doi:10.1097/ta.0b013e31825aa9ea","doi":"https://doi.org/10.1097/ta.0b013e31825aa9ea","is_oa":false,"landing_page_url":"https://doi.org/10.1097/ta.0b013e31825aa9ea","pdf_url":null,"source":{"id":"https://openalex.org/S4210177186","display_name":"The Journal of Trauma: Injury, Infection, and Critical Care","issn_l":"2163-0755","issn":["2163-0755","2163-0763"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Trauma and Acute Care Surgery","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/articles/PMC3698483","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Christopher Ward","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334536514","display_name":"Maine Medical Center","ror":"https://ror.org/03g5f5777","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334536514"]},{"id":"https://openalex.org/I4210123774","display_name":"Maine Medical Center","ror":"https://ror.org/034c1gc25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210102705","https://openalex.org/I4210123774"]},{"id":"https://openalex.org/I4210146345","display_name":"Maine Medical Center Research Institute","ror":"https://ror.org/03d1wq758","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210102705","https://openalex.org/I4210123774","https://openalex.org/I4210146345"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher Ward","raw_affiliation_strings":["Department of Surgery, Maine Medical Center, Portland 04102, USA. wardc1@mmc.org","Address for reprints: Christopher Ward, MD, Department of Surgery, Maine Medical Center, 22 Bramhall St, Portland, ME 04102","From the Department of Surgery (C.W., D.C., S.D.), Maine Medical Center, Portland","Maine Medical Center Research Institute (L.L., S.P.), Scarborough, Maine","Submitted: December 2, 2011, Revised: April 13, 2012, Accepted: April 16, 2012","This study was presented at the American College of Surgeons Committee on Trauma resident paper competition in Boston in October 2011 and the 25th annual meeting of the Eastern Association for the Surgery of Trauma, January 10\u201314, 2012, in Lake Buena Vista, Florida","email: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Maine Medical Center, Portland 04102, USA. wardc1@mmc.org","institution_ids":["https://openalex.org/I1334536514","https://openalex.org/I4210123774"]},{"raw_affiliation_string":"Address for reprints: Christopher Ward, MD, Department of Surgery, Maine Medical Center, 22 Bramhall St, Portland, ME 04102","institution_ids":["https://openalex.org/I1334536514","https://openalex.org/I4210123774"]},{"raw_affiliation_string":"From the Department of Surgery (C.W., D.C., S.D.), Maine Medical Center, Portland","institution_ids":["https://openalex.org/I1334536514","https://openalex.org/I4210123774"]},{"raw_affiliation_string":"Maine Medical Center Research Institute (L.L., S.P.), Scarborough, Maine","institution_ids":["https://openalex.org/I4210146345"]},{"raw_affiliation_string":"Submitted: December 2, 2011, Revised: April 13, 2012, Accepted: April 16, 2012","institution_ids":[]},{"raw_affiliation_string":"This study was presented at the American College of Surgeons Committee on Trauma resident paper competition in Boston in October 2011 and the 25th annual meeting of the Eastern Association for the Surgery of Trauma, January 10\u201314, 2012, in Lake Buena Vista, Florida","institution_ids":[]},{"raw_affiliation_string":"email: [email\u00a0protected]","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"David Ciraulo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334536514","display_name":"Maine Medical Center","ror":"https://ror.org/03g5f5777","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334536514"]},{"id":"https://openalex.org/I4210123774","display_name":"Maine Medical Center","ror":"https://ror.org/034c1gc25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210102705","https://openalex.org/I4210123774"]},{"id":"https://openalex.org/I4210146345","display_name":"Maine Medical Center Research Institute","ror":"https://ror.org/03d1wq758","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210102705","https://openalex.org/I4210123774","https://openalex.org/I4210146345"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Ciraulo","raw_affiliation_strings":["From the Department of Surgery (C.W., D.C., S.D.), Maine Medical Center, Portland","Maine Medical Center Research Institute (L.L., S.P.), Scarborough, Maine","Address for reprints: Christopher Ward, MD, Department of Surgery, Maine Medical Center, 22 Bramhall St, Portland, ME 04102","Submitted: December 2, 2011, Revised: April 13, 2012, Accepted: April 16, 2012","This study was presented at the American College of Surgeons Committee on Trauma resident paper competition in Boston in October 2011 and the 25th annual meeting of the Eastern Association for the Surgery of Trauma, January 10\u201314, 2012, in Lake Buena Vista, Florida","email: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Surgery (C.W., D.C., S.D.), Maine Medical Center, Portland","institution_ids":["https://openalex.org/I1334536514","https://openalex.org/I4210123774"]},{"raw_affiliation_string":"Maine Medical Center Research Institute (L.L., S.P.), Scarborough, Maine","institution_ids":["https://openalex.org/I4210146345"]},{"raw_affiliation_string":"Address for reprints: Christopher Ward, MD, Department of Surgery, Maine Medical Center, 22 Bramhall St, Portland, ME 04102","institution_ids":["https://openalex.org/I1334536514","https://openalex.org/I4210123774"]},{"raw_affiliation_string":"Submitted: December 2, 2011, Revised: April 13, 2012, Accepted: April 16, 2012","institution_ids":[]},{"raw_affiliation_string":"This study was presented at the American College of Surgeons Committee on Trauma resident paper competition in Boston in October 2011 and the 25th annual meeting of the Eastern Association for the Surgery of Trauma, January 10\u201314, 2012, in Lake Buena Vista, Florida","institution_ids":[]},{"raw_affiliation_string":"email: [email\u00a0protected]","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103177741","display_name":"Michael Coulter","orcid":"https://orcid.org/0000-0001-8098-2734","observed_orcids":["https://orcid.org/0000-0001-8098-2734"]},"institutions":[{"id":"https://openalex.org/I1334536514","display_name":"Maine Medical Center","ror":"https://ror.org/03g5f5777","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334536514"]},{"id":"https://openalex.org/I4210123774","display_name":"Maine Medical Center","ror":"https://ror.org/034c1gc25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210102705","https://openalex.org/I4210123774"]},{"id":"https://openalex.org/I4210146345","display_name":"Maine Medical Center Research Institute","ror":"https://ror.org/03d1wq758","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210102705","https://openalex.org/I4210123774","https://openalex.org/I4210146345"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael Coulter","raw_affiliation_strings":["From the Department of Surgery (C.W., D.C., S.D.), Maine Medical Center, Portland","Maine Medical Center Research Institute (L.L., S.P.), Scarborough, Maine","Address for reprints: Christopher Ward, MD, Department of Surgery, Maine Medical Center, 22 Bramhall St, Portland, ME 04102","Submitted: December 2, 2011, Revised: April 13, 2012, Accepted: April 16, 2012","This study was presented at the American College of Surgeons Committee on Trauma resident paper competition in Boston in October 2011 and the 25th annual meeting of the Eastern Association for the Surgery of Trauma, January 10\u201314, 2012, in Lake Buena Vista, Florida","email: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Surgery (C.W., D.C., S.D.), Maine Medical Center, Portland","institution_ids":["https://openalex.org/I1334536514","https://openalex.org/I4210123774"]},{"raw_affiliation_string":"Maine Medical Center Research Institute (L.L., S.P.), Scarborough, Maine","institution_ids":["https://openalex.org/I4210146345"]},{"raw_affiliation_string":"Address for reprints: Christopher Ward, MD, Department of Surgery, Maine Medical Center, 22 Bramhall St, Portland, ME 04102","institution_ids":["https://openalex.org/I1334536514","https://openalex.org/I4210123774"]},{"raw_affiliation_string":"Submitted: December 2, 2011, Revised: April 13, 2012, Accepted: April 16, 2012","institution_ids":[]},{"raw_affiliation_string":"This study was presented at the American College of Surgeons Committee on Trauma resident paper competition in Boston in October 2011 and the 25th annual meeting of the Eastern Association for the Surgery of Trauma, January 10\u201314, 2012, in Lake Buena Vista, Florida","institution_ids":[]},{"raw_affiliation_string":"email: [email\u00a0protected]","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078813984","display_name":"Steven Desjardins","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334536514","display_name":"Maine Medical Center","ror":"https://ror.org/03g5f5777","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334536514"]},{"id":"https://openalex.org/I4210123774","display_name":"Maine Medical Center","ror":"https://ror.org/034c1gc25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210102705","https://openalex.org/I4210123774"]},{"id":"https://openalex.org/I4210146345","display_name":"Maine Medical Center Research Institute","ror":"https://ror.org/03d1wq758","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210102705","https://openalex.org/I4210123774","https://openalex.org/I4210146345"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven Desjardins","raw_affiliation_strings":["From the Department of Surgery (C.W., D.C., S.D.), Maine Medical Center, Portland","Maine Medical Center Research Institute (L.L., S.P.), Scarborough, Maine","Address for reprints: Christopher Ward, MD, Department of Surgery, Maine Medical Center, 22 Bramhall St, Portland, ME 04102","Submitted: December 2, 2011, Revised: April 13, 2012, Accepted: April 16, 2012","This study was presented at the American College of Surgeons Committee on Trauma resident paper competition in Boston in October 2011 and the 25th annual meeting of the Eastern Association for the Surgery of Trauma, January 10\u201314, 2012, in Lake Buena Vista, Florida","email: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Surgery (C.W., D.C., S.D.), Maine Medical Center, Portland","institution_ids":["https://openalex.org/I1334536514","https://openalex.org/I4210123774"]},{"raw_affiliation_string":"Maine Medical Center Research Institute (L.L., S.P.), Scarborough, Maine","institution_ids":["https://openalex.org/I4210146345"]},{"raw_affiliation_string":"Address for reprints: Christopher Ward, MD, Department of Surgery, Maine Medical Center, 22 Bramhall St, Portland, ME 04102","institution_ids":["https://openalex.org/I1334536514","https://openalex.org/I4210123774"]},{"raw_affiliation_string":"Submitted: December 2, 2011, Revised: April 13, 2012, Accepted: April 16, 2012","institution_ids":[]},{"raw_affiliation_string":"This study was presented at the American College of Surgeons Committee on Trauma resident paper competition in Boston in October 2011 and the 25th annual meeting of the Eastern Association for the Surgery of Trauma, January 10\u201314, 2012, in Lake Buena Vista, Florida","institution_ids":[]},{"raw_affiliation_string":"email: [email\u00a0protected]","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027928145","display_name":"Lucy Liaw","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334536514","display_name":"Maine Medical Center","ror":"https://ror.org/03g5f5777","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334536514"]},{"id":"https://openalex.org/I4210123774","display_name":"Maine Medical Center","ror":"https://ror.org/034c1gc25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210102705","https://openalex.org/I4210123774"]},{"id":"https://openalex.org/I4210146345","display_name":"Maine Medical Center Research Institute","ror":"https://ror.org/03d1wq758","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210102705","https://openalex.org/I4210123774","https://openalex.org/I4210146345"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lucy Liaw","raw_affiliation_strings":["From the Department of Surgery (C.W., D.C., S.D.), Maine Medical Center, Portland","Maine Medical Center Research Institute (L.L., S.P.), Scarborough, Maine","Address for reprints: Christopher Ward, MD, Department of Surgery, Maine Medical Center, 22 Bramhall St, Portland, ME 04102","Submitted: December 2, 2011, Revised: April 13, 2012, Accepted: April 16, 2012","This study was presented at the American College of Surgeons Committee on Trauma resident paper competition in Boston in October 2011 and the 25th annual meeting of the Eastern Association for the Surgery of Trauma, January 10\u201314, 2012, in Lake Buena Vista, Florida","email: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Surgery (C.W., D.C., S.D.), Maine Medical Center, Portland","institution_ids":["https://openalex.org/I1334536514","https://openalex.org/I4210123774"]},{"raw_affiliation_string":"Maine Medical Center Research Institute (L.L., S.P.), Scarborough, Maine","institution_ids":["https://openalex.org/I4210146345"]},{"raw_affiliation_string":"Address for reprints: Christopher Ward, MD, Department of Surgery, Maine Medical Center, 22 Bramhall St, Portland, ME 04102","institution_ids":["https://openalex.org/I1334536514","https://openalex.org/I4210123774"]},{"raw_affiliation_string":"Submitted: December 2, 2011, Revised: April 13, 2012, Accepted: April 16, 2012","institution_ids":[]},{"raw_affiliation_string":"This study was presented at the American College of Surgeons Committee on Trauma resident paper competition in Boston in October 2011 and the 25th annual meeting of the Eastern Association for the Surgery of Trauma, January 10\u201314, 2012, in Lake Buena Vista, Florida","institution_ids":[]},{"raw_affiliation_string":"email: [email\u00a0protected]","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102819387","display_name":"Sarah M. Peterson","orcid":"https://orcid.org/0009-0004-2011-6366","observed_orcids":["https://orcid.org/0009-0004-2011-6366"]},"institutions":[{"id":"https://openalex.org/I1334536514","display_name":"Maine Medical Center","ror":"https://ror.org/03g5f5777","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334536514"]},{"id":"https://openalex.org/I4210123774","display_name":"Maine Medical Center","ror":"https://ror.org/034c1gc25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210102705","https://openalex.org/I4210123774"]},{"id":"https://openalex.org/I4210146345","display_name":"Maine Medical Center Research Institute","ror":"https://ror.org/03d1wq758","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210102705","https://openalex.org/I4210123774","https://openalex.org/I4210146345"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sarah Peterson","raw_affiliation_strings":["From the Department of Surgery (C.W., D.C., S.D.), Maine Medical Center, Portland","Maine Medical Center Research Institute (L.L., S.P.), Scarborough, Maine","Submitted: December 2, 2011, Revised: April 13, 2012, Accepted: April 16, 2012","This study was presented at the American College of Surgeons Committee on Trauma resident paper competition in Boston in October 2011 and the 25th annual meeting of the Eastern Association for the Surgery of Trauma, January 10\u201314, 2012, in Lake Buena Vista, Florida","email: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Surgery (C.W., D.C., S.D.), Maine Medical Center, Portland","institution_ids":["https://openalex.org/I1334536514","https://openalex.org/I4210123774"]},{"raw_affiliation_string":"Maine Medical Center Research Institute (L.L., S.P.), Scarborough, Maine","institution_ids":["https://openalex.org/I4210146345"]},{"raw_affiliation_string":"Submitted: December 2, 2011, Revised: April 13, 2012, Accepted: April 16, 2012","institution_ids":[]},{"raw_affiliation_string":"This study was presented at the American College of Surgeons Committee on Trauma resident paper competition in Boston in October 2011 and the 25th annual meeting of the Eastern Association for the Surgery of Trauma, January 10\u201314, 2012, in Lake Buena Vista, Florida","institution_ids":[]},{"raw_affiliation_string":"email: [email\u00a0protected]","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.0151,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.76788721,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"73","issue":"2","first_page":"447","last_page":"451"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11080","display_name":"Surgical site infection prevention","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11422","display_name":"Burn Injury Management and Outcomes","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/negative-pressure-wound-therapy","display_name":"negative pressure wound therapy","score":0.9900000095367432},{"id":"https://openalex.org/keywords/split-thickness-skin-graft","display_name":"split-thickness skin graft","score":0.9319999814033508},{"id":"https://openalex.org/keywords/skin-graft-fixation","display_name":"skin graft fixation","score":0.8389999866485596},{"id":"https://openalex.org/keywords/graft-survival","display_name":"graft survival","score":0.625},{"id":"https://openalex.org/keywords/graft-incorporation","display_name":"graft integration","score":0.722000002861023},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.8159999847412109},{"id":"https://openalex.org/keywords/vascular-ingrowth","display_name":"vascular ingrowth","score":0.9860000014305115},{"id":"https://openalex.org/keywords/wound-healing","display_name":"wound healing","score":0.7300000190734863},{"id":"https://openalex.org/keywords/pig-model","display_name":"porcine model","score":0.746999979019165},{"id":"https://openalex.org/keywords/von-willebrand-factor","display_name":"von Willebrand factor","score":0.847000002861023}],"concepts":[{"id":"https://openalex.org/C125473707","wikidata":"https://www.wikidata.org/wiki/Q9914","display_name":"H&E stain","level":3,"score":0.8925299048423767},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8265128135681152},{"id":"https://openalex.org/C2779232120","wikidata":"https://www.wikidata.org/wiki/Q1511599","display_name":"Negative-pressure wound therapy","level":3,"score":0.8234918117523193},{"id":"https://openalex.org/C2780269544","wikidata":"https://www.wikidata.org/wiki/Q1509074","display_name":"Wound healing","level":2,"score":0.6735784411430359},{"id":"https://openalex.org/C74864618","wikidata":"https://www.wikidata.org/wiki/Q2332446","display_name":"Staining","level":2,"score":0.6597764492034912},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.6490684747695923},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.5554915070533752},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4523807168006897},{"id":"https://openalex.org/C3018023364","wikidata":"https://www.wikidata.org/wiki/Q425265","display_name":"Significant difference","level":2,"score":0.43584805727005005},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.40337568521499634},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.14018410444259644},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000704","descriptor_name":"Analysis of Variance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001458","descriptor_name":"Bandages","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001707","descriptor_name":"Biopsy, Needle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006084","descriptor_name":"Graft Rejection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006085","descriptor_name":"Graft Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011897","descriptor_name":"Random Allocation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012016","descriptor_name":"Reference Values","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014841","descriptor_name":"von Willebrand Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014945","descriptor_name":"Wound Healing","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D016038","descriptor_name":"Skin Transplantation","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D016038","descriptor_name":"Skin Transplantation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D018919","descriptor_name":"Neovascularization, Physiologic","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D034421","descriptor_name":"Sus scrofa","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D062109","descriptor_name":"Dermatologic Surgical Procedures","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1097/ta.0b013e31825aa9ea","doi":"https://doi.org/10.1097/ta.0b013e31825aa9ea","is_oa":false,"landing_page_url":"https://doi.org/10.1097/ta.0b013e31825aa9ea","pdf_url":null,"source":{"id":"https://openalex.org/S4210177186","display_name":"The Journal of Trauma: Injury, Infection, and Critical Care","issn_l":"2163-0755","issn":["2163-0755","2163-0763"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Trauma and Acute Care Surgery","raw_type":"journal-article"},{"id":"pmid:22846954","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22846954","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The journal of trauma and acute care surgery","raw_type":"Comparative Study"},{"id":"pmh:oai:europepmc.org:2722603","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3698483","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3698483","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3698483","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Trauma Acute Care Surg","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2722603","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3698483","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[{"id":"https://openalex.org/G100136689","display_name":"Phase III  COBRE  in Vascular Biology","funder_award_id":"P30GM103392","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G5472358707","display_name":"Phase III  COBRE  in Vascular Biology","funder_award_id":"P30RR030927","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G5529095544","display_name":"COBRE in Stem Cell Biology and Regenerative Medicine","funder_award_id":"P20RR018789","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G8711097332","display_name":"COBRE in Stem Cell Biology and Regenerative Medicine","funder_award_id":"P20GM103465","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320310956","display_name":"Smith and Nephew","ror":"https://ror.org/03agge938"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W29194542","https://openalex.org/W95718650","https://openalex.org/W143727538","https://openalex.org/W1927733216","https://openalex.org/W1970366049","https://openalex.org/W1972884173","https://openalex.org/W1998996148","https://openalex.org/W2028359498","https://openalex.org/W2030894567","https://openalex.org/W2050214477","https://openalex.org/W2074643062","https://openalex.org/W2076169009","https://openalex.org/W2090333842","https://openalex.org/W2115572243","https://openalex.org/W2139303015","https://openalex.org/W2150312126","https://openalex.org/W2164406730","https://openalex.org/W2900573057","https://openalex.org/W4256286224","https://openalex.org/W4296300806","https://openalex.org/W6756205226"],"related_works":["https://openalex.org/W4400281778","https://openalex.org/W3080896542","https://openalex.org/W2780116575","https://openalex.org/W1530628043","https://openalex.org/W3118526556","https://openalex.org/W4385381192","https://openalex.org/W4281936150","https://openalex.org/W2967113984","https://openalex.org/W4385405306","https://openalex.org/W2981544930"],"abstract_inverted_index":{"BACKGROUND:":[0],"Negative-pressure":[1],"wound":[2,68],"therapy":[3],"(NPWT)":[4],"has":[5,20],"been":[6,21],"used":[7,22],"for":[8,12,119,140,160,177,283],"to":[9,23,32,62,144,242,268,292],"treat":[10],"wounds":[11],"more":[13,18],"than":[14],"15":[15],"years":[16],"and,":[17],"recently,":[19],"secure":[24],"split-thickness":[25,80,91,284],"skin":[26,49,81,92,285],"grafts.":[27],"There":[28],"are":[29,290],"some":[30],"data":[31,190],"support":[33],"this":[34,59],"use":[35],"of":[36,58,96,134,156,188,202,307],"NPWT,":[37],"but":[38],"the":[39,117,132,152,167,189,200,249,261,294,303],"actual":[40],"mechanism":[41],"by":[42,207,296],"which":[43,297],"NPWT":[44,65,170,250,262,278,298],"speeds":[45],"healing":[46],"or":[47,70,224],"improves":[48],"graft":[50,71,104,176,222,246,258,286],"take":[51],"is":[52],"not":[53,217],"entirely":[54],"known.":[55],"The":[56],"purpose":[57],"project":[60],"was":[61,194],"assess":[63],"whether":[64],"improved":[66,257],"angiogenesis,":[67],"healing,":[69],"survival":[72,180,223,259],"when":[73,276],"compared":[74,166],"with":[75],"traditional":[76,280],"bolster":[77,168,281],"dressings":[78],"securing":[79],"grafts":[82,93],"in":[83,199,221,248,260,273],"a":[84,228,253,270],"porcine":[85],"model.":[86],"METHODS:":[87],"We":[88,102,130,150,172,215,265],"performed":[89],"two":[90],"on":[94,106,227],"each":[95,161,175],"eight":[97],"30":[98],"kg":[99],"Yorkshire":[100],"pigs.":[101],"took":[103],"biopsies":[105],"postoperative":[107,182],"days":[108],"2,":[109],"4,":[110],"6,":[111],"8,":[112],"and":[113,115,127,164,169,179,234,252,279,302],"10":[114],"submitted":[116],"samples":[118,251],"immunohistochemical":[120,138],"staining,":[121],"as":[122,124,205],"well":[123],"standard":[125,232],"hematoxylin":[126,233],"eosin":[128,235],"staining.":[129],"measured":[131,206],"degree":[133,201],"vascular":[135,203],"ingrowth":[136,204,275],"via":[137],"staining":[139,236],"von":[141],"Willenbrand's":[142],"factor":[143],"better":[145,244],"identify":[146],"blood":[147,157],"vessel":[148,274],"epithelium.":[149],"determined":[151],"mean":[153,208],"cross-sectional":[154,209],"area":[155,211],"vessels":[158],"present":[159],"representative":[162],"specimen,":[163],"then":[165],"samples.":[171],"also":[173],"assessed":[174],"incorporation":[178,226,247],"at":[181],"day":[183],"10.":[184],"RESULTS:":[185],"Our":[186],"analysis":[187],"revealed":[191],"that":[192,238],"there":[193,240],"no":[195],"statistically":[196],"significant":[197,271],"difference":[198,220,272],"capillary":[210],"(p":[212],"=":[213],"0.23).":[214],"did":[216],"note":[218],"any":[219],"apparent":[225],"macroscopic":[229],"level,":[230],"although":[231],"indicated":[237],"microscopically,":[239],"seemed":[241],"be":[243],"subjective":[245],"nonsignificant":[254],"trend":[255],"toward":[256],"group.":[263],"CONCLUSION:":[264],"were":[266],"unable":[267],"demonstrate":[269],"comparing":[277],"methods":[282],"fixation.":[287],"More":[288],"studies":[289],"needed":[291],"elucidate":[293],"manner":[295],"exerts":[299],"its":[300],"effects":[301],"true":[304],"clinical":[305],"magnitude":[306],"these":[308],"effects.":[309]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2013,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}